• 제목/요약/키워드: Enzyme/metal bicatalysis

검색결과 2건 처리시간 0.017초

Lipase/Ruthenium-Catalyzed Dynamic Kinetic Resolution of β-Hydroxyalkylferrocene Derivatives

  • Lee, Han-Ki;Ahn, Yang-Soo
    • Bulletin of the Korean Chemical Society
    • /
    • 제25권10호
    • /
    • pp.1471-1473
    • /
    • 2004
  • An efficient dynamic kinetic resolution of racemic ${\beta}$-hydroxyalkylferrocene and 1,1'-bis( ${\beta}$-hydroxyalkyl)-ferrocene derivatives was achieved using lipase/ruthenium-catalyzed transesterification in the presence of an acyl donor. The racemic ${\beta}$-hydroxyalkylferrocene derivatives were successfully transformed to the corresponding chiral acetates of high optical purities in high yields.