• 한국자동차공학회논문집
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• 제17권4호
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• pp.10-15
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• 2009

Emission regulations on greenhouse gas(GHG) in automobiles have been stringent because of global warming effect. Over 90% of total GHG emission are carbon dioxides and about 20% of this $CO_2$ emission are emitted from automobiles. In this study, 110 vehicles were tested on a chassis dynamometer and $CO_2$ emissions and fuel economy were measured in order to investigate the characteristics of $CO_2$ emission factor from passenger vehicles which are the most dominant vehicle type in Korea. The characteristics of emissions in accordance with displacements, gross vehicle weight, NIER and CVS-75 speed mode were discussed. It was found that vehicles having larger displacement, heavier gross vehicle weight, automatic transmission and specially at cold start emitted more $CO_2$ emissions. From these results, correlation between $CO_2$ emission and fuel economy was also obtained. This study may contribute to evaluate domestic greenhouse gas emissions and establish national policies on climate changes in future.

• 한국산학기술학회논문지
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• 제19권2호
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• pp.516-529
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• 2018

기업의 사회적 책임에 대한 인식과 요구가 증대되면서, 사회적 기여를 위한 기업의 활동이 다양해지고 있는 추세이다. 그럼에도 불구하고, 정기적으로 실시하는 관련 설문 조사에 따르면 기업의 사회 공헌활동에 대해 국민이 만족하지 못하는 것으로 나타났으며, 기업과 국민의 사회공헌활동에 대한 관점이 다른 것을 파악할 수 있었다. 이에 따라 다양한 사회공헌활동을 구체적으로 분류하여 사회에 미치는 영향을 파악하고자 한다. 본 연구에서는 기업 사회공헌활동과 성과에 대한 연관성을 파악하고자 사회공헌활동을 "사회문화적자원 활동", "사회간접적자원 활동" 및 "경제적자원 활동" 총 3가지 요인으로 분류하고, 요인별로 기업 간 연계활동과 지역발전성과에 미치는 영향을 파악하였다. 분석결과, 첫째, '사회문화적자원'과 '사회간접적자원' 활동은 지역 내 '기업 간 연계 활동'에 정(+)의 영향을 미치는 것으로 나타났다. 둘째, '지역 내 기업 간 연계' 활동이 활발할수록 '지역발전성과'에 정(+)의 영향을 미치는 것으로 나타났다. 셋째, '경제적자원' 활동은 '지역발전성과'에 정(+)의 영향을 미치는 것으로 나타났으며, 넷째, '사회문화적자원'과 '사회간접적자원' 활동은 지역 내 기업 간의 연계를 통해 '지역발전성과'에 간접적인 정(+)의 영향을 미치는 것으로 나타났다. 본 연구를 바탕으로 기업의 사회공헌활동과 성과에 대한 연관성을 정량적으로 파악하고 제시하였다.

• 한국자동차공학회논문집
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• 제19권1호
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• pp.101-108
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• 2011

Understanding the exhaust gas recirculation (EGR) cooler fouling in diesel engine is important factor in the durability characteristic of a EGR system. We develope a test rig and PM feeder using carbon black to examine the effect of fouling on EGR cooler devices those were consisted of flat and shell & tube type. The EGR cooler fouling process is a complex interaction involving heat exchanger shape, boundary condition, constitutes, chemistry and operating mode. As the soot deposited to EGR cooler, these formed a thin deposit layer that was less heat exchange than the fresh status of tube enclosing the exhaust gas, resulting in lower heat exchange effectiveness in both type coolers. But these deposits caused different results in pressure drop, it is increased in flat type, but decreased in Shell & tube type of EGR cooler. A cause was estimated from a change of the flow structure and a decrease of contact area as the EGR cooler fouling.

• 환경영향평가
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• 제12권5호
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• pp.341-348
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• 2003

Seasonal characteristics of water quality and effect of the freshwater discharge during open the tide embankment in Haechang Bay were evaluated. In the freshwater, where interior of the tide embankment, COD and Chl-a exceeded about 4mg/L and $10mg/m^3$, respectively, independent of season, while in the seawater they showed high values in April and July in contrast to the other period due to input of freshwater and increase of phytoplankton, respectively. The content of seawater inorganic nitrogen maintained a relatively high level at inner part of the bay, whereas high values of inorganic phosphorus content was distributed at all over the bay. The limiting factor for algal growth was nitrogen with respect to the N/P ratio. The compass of influence by the freshwater discharge in April was quite different with water pollutants. As a result of the salinity variation with time, the freshwater extended strongly to offshore from the surface layer without mixing with depth when open the tide embankment, and reached within about one hour at a station which is 3.5km from the tide embankment. To effective water quality management of Haechang Bay, discharge rate and pollutant loads should be controlled.

• 한국환경농학회지
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• 제40권3호
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• pp.194-202
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• 2021

BACKGROUND: Towards achievement of sustainable agriculture, using microbial inoculants may present promising alternatives without adverse environmental effects; however, there are challenging issues that should be addressed in terms of effectiveness and ecology. Viability and stability of the bacterial inoculants would be one of the major issues in effectiveness of microbial pesticide uses, and the changes within the indigenous microbial communities by the inoculants would be an important factor influencing soil ecology. Here we investigated the stability of the introduced bacterial strains in the soils planted with barley and its effect on the diversity shifts of the rhizosphere soil bacteria. METHODS AND RESULTS: Two different types of bacterial strains of Bacillus thuringiensis and Shewanella oneidensis MR-1 were inoculated to the soils planted with barley. To monitor the stability of the inoculated bacterial strains, genes specific to the strains (XRE and mtrA) were quantified by qPCR. In addition, bacterial community analyses were performed using v3-v4 regions of 16S rRNA gene sequences from the barley rhizosphere soils, which were analyzed using Illumina MiSeq system and Mothur. Alpha- and beta-diversity analyses indicated that the inoculated rhizosphere soils were grouped apart from the uninoculated soil, and plant growth also may have affected the soil bacterial diversity. CONCLUSION: Regardless of the survival of the introduced non-native microbes, non-indigenous bacteria may influence the soil microbial community and diversity.

• Geomechanics and Engineering
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• 제34권6호
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• pp.649-664
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• 2023

Structural inertial interaction is a representative the effect of dynamic soil-foundation-structure interaction (SFSI), which leads to a relative displacement between soil and foundation, period lengthening, and damping increasing phenomena. However, for a system with a significantly heavy foundation, the dynamic inertia of the foundation influences and interacts with the structural seismic response. The structure-to-foundation mass ratio (MR) quantifies the distribution of mass between the structure and foundation for a structure on a shallow foundation. Although both systems exhibit the same vertical factor of safety (FS_v), the MR and corresponding seismic responses attributed to the structure and foundation masses may differ. This study explored the influence of MR on the permanent deformation and seismic response of soil-foundation-structure system considering SFSI via numerical simulations. Given that numerous dimensionless parameters of SFSI described its influence on the structural seismic response, the parameters, except for MR and FS_v, were fixed for the sensitivity analysis. The results demonstrated that the foundation inertia of heavier foundations induced more settlement due to sliding behavior of heavily-loaded systems. Moreover, the structural inertia of heavier structures evidently exhibited foundation rocking behavior, which results in a more elongated natural period of the structure for lightly-loaded systems.

• Biomolecules & Therapeutics
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• 제31권5호
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• pp.550-558
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• 2023

Hair loss is a common condition that can have a negative impact on an individual's quality of life. The severe side effects and the low efficacy of current hair loss medications create unmet needs in the field of hair loss treatment. Hyaluronan and Proteoglycan Link Protein 1 (HAPLN1), one of the components of the extracellular matrix, has been shown to play a role in maintaining its integrity. HAPLN1 was examined for its ability to impact hair growth with less side effects than existing hair loss treatments. HAPLN1 was predominantly expressed in the anagen phase in three stages of the hair growth cycle in mice and promotes the proliferation of human hair matrix cells. Also, recombinant human HAPLN1 (rhHAPLN1) was shown to selectively increase the levels of transforming growth factor-β receptor II in human hair matrix cells. Furthermore, we observed concomitant activation of the ERK1/2 signaling pathway following treatment with rhHAPLN1. Our results indicate that rhHAPLN1 elicits its cell proliferation effect via the TGF-β2-induced ERK1/2 pathway. The prompt entering of the hair follicles into the anagen phase was observed in the rhHAPLN1-treated group, compared to the vehicle-treated group. Insights into the mechanism underlying such hair growth effects of HAPLN1 will provide a novel potential strategy for treating hair loss with much lower side effects than the current treatments.

• 한국환경보건학회지
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• 제23권2호
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• pp.72-82
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• 1997

This study was performed to investigate the effect of co-existence of BPMC, carbaryl and chlorothalonil on the short-term bioconcentration factor in Carassius auratus(goldfish). The fishes were exposed to the combined treatment of BPMC, carbaryl and chlorothalonil (0.05 ppm+0.05 ppm+0.005 ppm, 0.05 ppm+0.05 ppm+0.010 ppm, 0.05 ppm+0.10 ppm+0.005 ppm, 0.10 ppm+0.05 ppm+0.005 ppm, 0.10 ppm+0.10 ppm+0.005 ppm) for 3 and 5 days, respectively. BPMC, carbaryl and chlorothalonil in fish and in test water were extracted with n-hexane and acetonitrile. GC-ECD was used to detect and quantitate BPMC, carbaryl and chlorothalonil. 3-day and 5-day bioconcentration factors(BCF$_3$ and BCF$_5$) of each pesticide were calculated from the quantitation results. The depuration rate of each pesticide-from the whole body of fish was determined over the 72-h period after combined treatment.The results were as follows: BCF$_3$ values of BPMC were 4.163, 4.011, 4.122, 4.750 and 4.842 when the concentration of BPMC+ carbaryl+chlorothalonil in combined treatment were 0.05 ppm+0.05 ppm+0.005 ppm, 0.05 ppm+0.05 ppm+0.010 ppm, 0.05 ppm+0.10 ppm+0.005 ppm, 0.10 ppm+0.05 ppm+0.005 ppm and 0.10 ppm+ 0.10 ppm+0.005 ppm. BCF$_5$ values of BPMC were 3.465, 3.270, 3.472, 3.162, 4.227 and 4.157, respectively, under the above conditions. While BCF$_3$ values of carbaryl were 4.583, 4.642, 4.571, 3. 637 and 3.529, respectively, and BCF$_5$ values of carbaryl were 3.932, 3.797, 3.843, 4.293 and 4.132, respectively, under the conditions. While BCF$_3$ values of chlorothalonil were 2.024, 3.532, 2.213, 2.157 and 2.271, respectively, and BCF$_5$ of chlorothalonil were 6.712, 7.013, 6.457, 6.694 and 6.597, respectively, under the conditions. Depuration rate constants of BPMC were 0.019, 0.018, 0.020, 0.022 and 0.021 when the concentration of BPMC+carbaryl+chlorothalonil in combined treatment were the same as above. And depuration rate constants of carbaryl were 0.030, 0.029, 0.030, 0.029 and 0.031, respectively, under the same condition of pesticide mixtures. While depuration rate constants of chlorothalonil were 0.004, 0.004, 0.003, 0.004 and 0.003, respectively, under the same condition. It was observed that no significant differences of BCFs and concentrations of the compounds in fish extracts, test water between combined treatment and single treatment. It was considered that no appreciable interaction at experimental concentrations was due to low concentrations, near environmental level, 0.005-0.1 ppm. Coexistence of BPMC, carbaryl and chlorothalonil had no effect on depuration rate of each pesticide and depuration rate of chlorothalonil was investigated 1/8 and 1/6 slower than those of carbaryl and BPMC in combined treatment. It is similar result in comparison with single treatment. Therefore, it is considered that the persistence of chlorothalonil in fish body would be higher than those of carbaryl and BPMC.

• 한국환경성돌연변이발암원학회지
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• 제22권2호
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• pp.83-89
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• 2002

The single cell gel electrophoresis (comet) assay is one of the useful tools for the study of genetic damage in humans exposed to environmental mutagens and carcinogens. This study was undertaken to evaluate the status of DNA damage in peripheral lymphocytes depending on their sex, age, smoking habits, and other factors in normal healthy Korean population. The 99 volunteers included in the study and out of these, 36 volunteers were smoker and 63 volunteers were non-smoker aged between 20-59 years. All individual answered a questionnaire that assessed their general information including smoking habits and the extent of the environmental tobacco smoke (ETS) exposure, and blood samples were obtained. There was a statistically significant difference in the extent of DNA damage between smoker and non-smoker (p<0.001). A significant difference was also observed between male and female (p<0.001) and amongst the different group of age (p<0.005), however, correlation analysis showed that only smoking habit was a significant factor for DNA damage. No significant effect of smoking duration, number of cigarettes smoking a day, SPY (smoke pack years) in smokers and environmental tobacco smoke exposure in non-smokers on the status of DNA damage was observed.

• 한국축산시설환경학회지
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• 제20권4호
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• pp.147-154
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• 2014

Heat stress is a significant burden to animal production in most areas of the world. Improving our knowledge of physiological and metabolic mechanisms of acclimation may contribute to the development of procedures that may help to maintain health and production efficiency under hot temperature. The effect of Ulmus pumila (UP) extract in inducing Heat Shock Proteins (HSPs) expression in heat-stressed RAW264.7 macrophage cells was investigated. Cell viability assay showed a dose dependent increase in cells after treatment with UP for 24 hours. RT-PCR and western blot analysis showed that increasing concentrations of UP induce the expression of Heat Shock Factor 1 (HSF1) and dose dependently upregulated the expression of Heat shock protein 70 (Hsp70) and Hsp90. LPS-induced nitric oxide was dose-dependently reduced while phagocytic activity greatly recovered with UP treatment. These data demonstrated that UP can be a potential candidate in the development of cytoprotective agent against heat stress.