• Journal of Digital Convergence
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• v.15 no.8
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• pp.85-93
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• 2017

Kolao Holdings has a dominant market share in Lao Automotive market, wherever Japanese automotive makers have the biggest market share in other Southeast Asian countries. The company that was founded by a Korean in Laos has firstly listed on the Korean Stock Market among companies which Koreans founded abroad. Applying the model of Exploration and Exploitation by March(1991), this study is aiming at finding out what the management strategy leaded to Kolao's success in Laos. In addition, this study figured out the company's process innovation and cultural innovation. In result, it is summarized that the exploitation activities contributed to the entry to Lao market, the exploration activities to expanding market to neighboring countries, the process innovation to creation profits, and cultural innovation to sustainable growth.

• Journal of the Korea Society of Computer and Information
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• v.4 no.1
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• pp.99-113
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• 1999

The Korean distribution market is now faced with various difficult problems. for instance, the withering of domestic demand by effect of IMF support system, the competitive foreign enterprise's entry into domestic distribution market by opening of its market, and the diversity and unexpected change of consumers' needs. Through the comparative study with Japanese distribution industry, we could find out the outline of information strategy that Korean wholesalers and retailers can solve such problems and stand at competitive advantage in Korean distribution market. We use information system in order to get data for consumers' needs quick and diversely. analyze those accurately, and put those into merchandising. So we have to work out the information strategy in line with the three-point principle, such as the integration or linking of information systems, the sustaining improvement and development of information systems, and the sharing of information.

• Journal of the Korean Institute of Landscape Architecture
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• v.29 no.6
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• pp.62-71
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• 2002

How parks are to be made in the twenty-first century should certainly be different. This is the inevitable conclusion of the recent significant international design competition for Downsview Park in Toronto, 2000. The purpose of this critical study is to investigate new strategies for urban park design manifested in the proposals of that competition and to explore alternative ways of landscape design that could solve the recent crisis of urban parks. Tree City, the winning entry, and other final entries proclaim that city is park and park is city. In this sense, Downsview Park marks the end of traditional Olmstedian parks and the dichotomy between city(culture) and park(nature). Rem Koolhaas and Bruce Mau's Tree City will become the model for urban park design in the near future. There are three reasons for this. First, its design is a strategy rather than a form. We can interpret that Tree City is to be developed over time as directed by six strategies: grow the park, manufacture nature, 1000 pathways, sacrifice and save, curate culture, destination and dispersal. Second, it places faith in landscape as a revenue generator instead of a fiscal liability. Third, its implementation is possible with crude installation, requiring virtually no craft. Koolhaas and Mau intend for Downsview to be an environment that is never actually designed but is formed through natural succession, cultural action, and programmatical insertions. Rather than designed objects and formal solutions, their strategy is to allow the landscape to evolve with changing uses.

• Journal of Microbiology
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• v.42 no.4
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• pp.361-364
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• 2004

Internal ribosome entry site (IRES) of the hepatitis C virus (HCV) is known to be essential for HCV replication and most conserved among HCV variants. Hence, IRES RNA is a good therapeutic target for RNA-based inhibitors, such as ribozymes. We previously proposed a new anti-HCV modulation strategy based on trans-splicing ribozymes, which can selectively replace HCV transcripts with a new RNA that exerts anti-HCV activity. To explore this procedure, sites which are accessible to ribozymes in HCV IRES were previously determined by employing an RNA mapping method in vitro. In this study, we evaluate the intracellular accessibility of the ribozymes by comparing the trans-splicing activ­ities in cells of several ribozymes targeting different sites of the HCV IRES RNA. We assessed the intra­cellular activities of the ribozymes by monitoring their target-specific induction degree of both reporter gene activity and cytotoxin expression. The ribozyme capable of targeting the most accessible site iden­tified by the mapping studies then harbored the most active trans-splicing activity in cells. These results suggest that the target sites predicted to be accessible are truly the most accessible in the cells, and thus, could be applied to the development of various RNA-based anti-HCV therapies.

• Advances in aircraft and spacecraft science
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• v.4 no.4
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• pp.449-465
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• 2017

The aim of the present work is to present a computational study of the non-linear aero-elastic behavior of a multi-layered Thermal Protection System (TPS). The severity of atmospheric re-entry conditions is due to the combination of high temperatures, high pressures and high velocities, and thus the aero-elastic behavior of flexible structures can be difficult to assess. In order to validate the specific computational model and the overall strategy for structural and aerodynamics analyses of flexible structures, the simplified TPS sample tested in the 8' High Temperature Tunnel (HTT) at NASA LaRC has been selected as a baseline for the validation of the present work. The von $K{\acute{a}}rm{\acute{a}}n^{\prime}s$ three dimensional large deflection theory for the structure and a hybrid Raleigh-Ritz-Galerkin approach, combined with the first order Piston Theory to describe the aerodynamic flow, have been used to derive the equations of motion. The paper shows that a good description of the physical behavior of the fabric is possible with the proposed approach. The model is further applied to investigate structural and aero-elastic influence of the number of the layers and the stitching pattern.

• Nuclear Engineering and Technology
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• v.28 no.3
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• pp.257-264
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• 1996

The conventional Equipment Environment Qualification (EEQ) envelope is developed based on the containment responses during the design basis events. The Safety Depressurization System (SDS) design without In-containment Refueling Water Storage Tank (IRWST) adopted in the Ulchin 3&4 challenges the conventional EEQ envelope during long term Feed and Bleed (F&B) operation due to the direct discharge of high mass and energy into the containment. Therefore, it is necessary to confirm that the containment pressure and temperature history during the long term F&B operation does not violate the conventional EEQ envelope. However, this subject has never been quantitatively assessed before. To investigate the success path of long term F&B operation this paper analyzes the thermal hydraulic response of the containment and Reactor Coolant System (RCS) until the completion of depressurization and cooldown of RCS into Shutdown Cooling System (SCS) entry condition. It is found that the SCS entry condition can be reached within 6 hours without violating the EEQ curve by proper operation of SDS valves, High Pressure Safety Injection (HPSI) pumps and active Containment Heat Removal System (CHRS). The suggested strategy not only demonstrates the feasibility of long term F&B operation but also can be utilized in the preparation of Emergency Procedure Guidelines (EPGs)

• Current Industrial and Technological Trends in Aerospace
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• v.8 no.1
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• pp.104-111
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• 2010

This paper deals with the world civil helicopter market scope, world market analysis based on the operating fleet ages, preconditions for market entry, and market forecast which are necessary for Korean industry to enter into world market. According to the analysis, the heavy single class demand is rapidly declined. The demand is moving toward the heavier class than that operated now. Korean industry had better have strategic positioning to heavy twin and light medium twin classes. A considerable amount of Korean civil helicopter based on Surion can be sold if there are appropriate efforts for price, specification, marketing strategy and so on.

• The Journal of Asian Finance, Economics and Business
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• v.8 no.3
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• pp.267-275
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• 2021

This study investigates the relationship between cultural distance and entry mode choice, where the foreign investor firm and the host country are both from emergent economies. Within this framework, research is limited and the issue is whether companies, regardless of their specific situations, have the same strategy when they meet a high degree of uncertainty in the host environment. In this study, we focused on the influence of informal institutional factors: cultural distance, that has been extensively analyzed in international business, measured by Kogut and Singh index and defined according to Hofstede, Globe Project and Schwartz approaches. The general trend derived from prior research proves that when a company from a developed country is involved; overall more enthusiasm is shown for wholly-owned subsidiaries rather than joint venture. This result still stands validated for corporations from this emergent economy area. Our analysis of a sample of 163 FDI in the Kingdom of Saudi Arabia (KSA) using logistic binary regression model reveals that the foreign firms prefer to establish wholly-owned subsidiaries in the host country over entering into a joint venture with a local firm, taking into consideration the large cultural distance.

• BMB Reports
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• v.56 no.9
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• pp.502-507
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• 2023

Photobiomodulation therapy has been proposed as a promising therapeutic approach for retinal degenerative diseases. However, its effect on the regenerative capacity in mammalian retina and its intracellular signalling mechanisms remain unknown. Here, we show that photobiomodulation with 670 nm light stimulates Müller glia cell cycle re-entry and dedifferentiation into a progenitor-like state in both the uninjured and injured retina. We also find that 670 nm light treatment inhibits the Hippo pathway, which is activated in Müller glia following NaIO₃-induced retinal injury. YAP, a major downstream effector of the Hippo signalling pathway was translocated into the nucleus of Müller glia along with YAP dephosphorylation in retina treated with 670 nm light. Deficiency of YAP attenuated Müller glia cell cycle re-entry and dedifferentiation. Our data reveal that the Hippo-YAP signalling pathway is associated with the photostimulatory effect on regenerative response in mammalian retina, and suggest a potential therapeutic strategy for retinal degenerative diseases.

• International conference on construction engineering and project management
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• 2005.10a
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• pp.1007-1012
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• 2005

Although the design-build (DB) delivery system has been taking great strides in the world and relevant researches have also been quite abundant, few studies have dealt with its potential impacts on the construction industry as a whole. This research first identified the potential entry barrier factors, which may hinder the market access, based on the theory of industrial economics and characteristics of DB project. Then through a nation-wide questionnaire survey involving 103 construction contractors and engineering consultants, the influences of each factor on company's competitiveness and corporate strategies were scrutinized, and consequently, the evolution of the construction industry was examined. It is found that as opposed to the traditional design-bid-build delivery system, the DB delivery system elevates competitive advantages of large organizations in terms of the financial capability, working experience, human resource, and administrative strength, and among them, the financial strength was concluded to be the most significant force in differentiating corporate strategies and widening the gap of competitiveness between companies. It is inferred if the government extensively adopts DB delivery system, large organizations that already possess the competitive advantage tend to obtain both design and construction abilities, and dominate the DB market. Small and medium sized companies will find little room to maneuver and be forced to become specialty sub-contractors.