• Journal of Biomedical Engineering Research
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• v.42 no.3
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• pp.71-79
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• 2021

Currently, the naked eyes-based diagnosis of bone metastases on CT images relies on qualitative assessment. For this reason, there is a great need for a state-of-the-art approach that can assess and follow-up the bone metastases with quantitative biomarker. Radiomics can be used as a biomarker for objective lesion assessment by extracting quantitative numerical values from digital medical images. In this study, therefore, we evaluated the clinical applicability of non-invasive and objective bone metastases computer-aided diagnosis using radiomics-based biomarkers in CT. We employed a total of 21 approaches consist of three-classifiers and seven-feature selection methods to predict bone metastases and select biomarkers. We extracted three-dimensional features from the CT that three groups consisted of osteoblastic, osteolytic, and normal-healthy vertebral bodies. For evaluation, we compared the prediction results of the classifiers with the medical staff's diagnosis results. As a result of the three-class-classification performance evaluation, we demonstrated that the combination of the random forest classifier and the sequential backward selection feature selection approach reached AUC of 0.74 on average. Moreover, we confirmed that 90-percentile, kurtosis, and energy were the features that contributed high in the classification of bone metastases in this approach. We expect that selected quantitative features will be helpful as biomarkers in improving the patient's survival and quality of life.

• Journal of Microbiology and Biotechnology
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• v.31 no.2
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• pp.207-216
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• 2021

Supplement of high-protein food plays an important role in improving the symptoms of malnutrition and the immune capacity of the body, but the association of high-protein diet and gut microbiota remained unaddressed. Here, we systematically analyzed the internal organs and gut microbiota in C57(WT) or PD-1H-depleted (KO) mice (T cells were activated) fed with pupae or feed for six weeks. We observed that the body weight gain in the mice fed with pupae increased less significantly than that of the feed group, while the villi and small intestine lengths in the pupa group were reduced compared with that of mice given feed. However, the average body weight of the KO mice increased compared with that of the WT mice fed with pupae or feed. Pupae increased the concentration of blood glucose in WT, but not in KO mice. Moreover, in the feed group, there was no difference in the weight of the internal organs between the WT and KO mice, but in the pupae-fed group, liver weight was decreased and spleen weight was increased compared with that of KO mice. The amounts/plural/amounts of Melainabacteria, Chloroflexi, and Armatimonadetes were specifically upregulated by pupae, and this upregulation was weakened or eliminated by PD-1H depletion. Some bacteria with high abundance in the feed-fed KO mice, such as Deferribacteres, Melainabacteria, Acidobacteria, Bacteroidetes, Spirochaetes and Verrucomicrobia, were decreased in pupae-fed KO mice, and Proteobacteria and Deinococcus were specifically enriched in pupae-fed KO mice. Bacteroidetes, Firmicutes and Akkermansia were associated with weight loss in the pupae-fed group while Lachnospiraceae and Anaerobiospirillum were related glucose metabolism and energy consumption. Based on high-throughput sequencing, we discovered that some gut bacteria specifically regulated the metabolism of a high-protein diet, and PD-1H deficiency improved life quality and sustained blood glucose. Moreover, PD-1H responses to high-protein diet through modulating the type and quantity of gut bacteria. These findings provide evidence about the association among gut microbiota, T cell activation (for PD-1H depletion) and high-protein diet metabolism, have important theoretical significance for nutrition and health research.

• KIPS Transactions on Software and Data Engineering
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• v.10 no.4
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• pp.133-142
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• 2021

With the recent advancements of deep learning, companies such as smart home, healthcare, and intelligent transportation systems are utilizing its functionality to provide high-quality services for vehicle detection, emergency situation detection, and controlling energy consumption. To provide reliable services in such sensitive systems, deep learning models are required to have high accuracy. In order to develop a deep learning model for analyzing previously mentioned services, developers should utilize the state of the art deep learning models that have already been verified for higher accuracy. The developers can verify the accuracy of the referenced model by validating the model on the dataset. For this validation, the developer needs structural information to document and apply deep learning models, including metadata such as learning dataset, network architecture, and development environments. In this paper, we propose a description language that represents the network architecture of the deep learning model along with its metadata that are necessary to develop a deep learning model. Through the proposed description language, developers can easily verify the accuracy of the referenced deep learning model. Our experiments demonstrate the application scenario of a deep learning description document that focuses on the license plate recognition for the detection of illegally parked vehicles.

• Composites Research
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• v.35 no.4
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• pp.277-282
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• 2022

In this study, a smart material applicable to speed bumps was developed using low-cost starch and waterbased suspensions, and their properties were investigated. Viscosity and shear stress according to the shear rate was measured by a rheometer to observe shear thickening behavior according to starch concentration. The shear thickening phenomenon and applicability to speed bumps were identified macroscopically via drop weight test and bike driving test, measuring the vibration after impact with a driving speed of 5-25 km/h. As a result of the viscosity measurement, shear thickening occurred after the shear thinning region at the beginning, and the critical strain causing the shear thickening phenomenon decreased as the concentration of starch increased. Also, the viscosity and shear stress increased significantly with the increase of the starch concentration. As a result of the drop weight test and the bike driving test, the suspension was changed to a solid-like state in a short time, and the impact energy was absorbed in the fluid. The shear thickening phenomenon easily occurred as the concentration of the fluid and the applied impact (velocity) increased. Therefore, it can be proposed the development of a smart speed bump material that operates in the range of 5-25 km/h with a Non-Newtonian fluid based on water and starch.

• Journal of the Korea Convergence Society
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• v.12 no.11
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• pp.81-90
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• 2021

There are various optimization problems in real world and research continues to solve them. An optimization problem is the problem of finding a combination of parameters that maximizes or minimizes the objective function. Harmony search is a population-based metaheuristic algorithm for solving optimization problems and it is designed to mimic the improvisation of jazz music. Harmony search has been actively applied to optimization problems in various fields such as civil engineering, computer science, energy, medical science, and water quality engineering. Harmony search has a simple working principle and it has the advantage of finding good solutions quickly in constrained optimization problems. Especially there are various application cases showing high accuracy with a low number of iterations by improving the solution through the empirical derivative. In this paper, we explain working principle of Harmony search and classify the leading research in recent 3 years, review them according to category, and suggest future research directions. The research is divided into review by field, algorithmic analysis and theory, and application to real world problems. Application to real world problems is classified according to the purpose of optimization and whether or not they are hybridized with other metaheuristic algorithms.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.50 no.12
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• pp.829-838
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• 2022

This study conducts Hypervelocity Impact(HVI) simulations considering space objects with various shapes and different impact angles. A commercial nonlinear structural dynamics analysis code, LS-DYNA, is used for the present simulation study. The Smoothed Particle Hydrodynamic(SPH) method is applied to represent the impact phenomena with hypervelocity. Mie-Grüneisen Equation of State and Johnson-Cook material model are used to consider nonlinear structural behaviors of metallic materials. The space objects with various shapes are modeled as a sphere, cube, cylinder, and cone, respectively. The space structure is modeled as a thin plate(200 mm×200 mm×2 mm). HVI simulations are conducted when space objects with various shapes with 4.119 km/s collide with the space structures, and the impact phenomena such as a debris cloud are analyzed considering the space objects with various shapes having the same mass at the different impact angles of 0°, 30° and 45° between the space object and space structure. Although space objects have the same kinetic energy, different debris clouds are generated due to different shapes. In addition, it is investigated that the size of the debris cloud is decreased by impact angles.

• Industry Promotion Research
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• v.7 no.3
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• pp.103-113
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• 2022

In this study, in the Nativity birth chart of Classic Astrology, the study was conducted under the premise that 'If the natives are born with different structures to govern their diseases, diseases may appear differently in the lives of natives.' did. In the birth chart, an individual's innate health was analyzed through the strengths and weaknesses of sign, planets, and aspects. In the case of managing congenital diseases, we studied the aspect relationship between the native's ASC constellation and the fixed star and planet in the Nativity Birth Chart. In the case of controlling acquired diseases, it was judged by examining the constellations, rulers, and planets of the 6^th house that control diseases in the Nativity birth chart. In the case of acquired diseases, natives may be exposed to various accidents and diseases throughout their lives. So, we looked at the relationship between diseases through the energy and weakness of the planet coming through Pirdaria, the aspect relationship with the planet, and fixed star. As a result of the study, a native's health status is given differently depending on the strength and weakness of the innate sign and planet in the Nativity Birth Chart. And it has been proven that the health of the native is determined by the state of the 6^th House, who rules over disease, and the disease and accidents that come from Direction are determined by the relationship between the planet and the aspect coming from Pirdaria.

• Journal of Aerospace System Engineering
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• v.17 no.1
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• pp.42-50
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• 2023

In this study, hexagonal ferrite powder with chemical formula SrZn_2-xCo_xFe₁₆O₂₇ was synthesized by a solid-state reaction method and its electromagnetic (EM) wave absorption characteristics were evaluated in the frequency range of 0.1-18 GHz with absorber thickness range of 0 - 10 mm. Reflection loss (RL) affecting electromagnetic wave absorption performance was calculated based on the transmission line theory using measured complex permeabilities and permittivities. RL spectra were also directly measured for some samples. They were well matched with calculated results. High-frequency complex permeability characteristics were changed gradually according to the amount of Co substitution (x). The EM wave absorption frequency band could be tuned accordingly. Hexaferrite samples with x = 1.0, 1.25, and 1.5 exhibited remarkable maximum electromagnetic wave absorption performances with minimum RL (RL_min) lowered than -50 dB. They also showed a very broad frequency band (Δf > 10 GHz) in which more than 90% of the EM wave energy absorption occurred (RL ≤ -10 dB).

• Korean Journal of Poultry Science
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• v.14 no.1
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• pp.9-13
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• 1987

Three-week-old, broiler-type, mixed sex chicks were divided into replicate groups of 10 birds each and fed for 5 weeks. The wheat bran was defatted and added at 0, 10 and 20% levels. A fourth group received the 20% wheat bran plus a cellulase enzyme added at the level of 0.008%. After a five-week experimental period without a marker a 24-pen battery on the four diets were supplemented with 1% chromic oxide and fed 100g daily. After a 2-day preliminary period, feces were collected three times daily from each diet group for two days at 2, 4 or 8 hours after feeding. At the end of 4 days, within each diet group, birds were randomly selected for slaughter at 2, 4 or 8 hours after feeding and the entire gastrointestinal tract was removed and ligated to form five compartments. The lengths of each segment were measured after straightening, and the gizzard was emptied and weighed. The summarized data showed that the group fed on the high-energy basal diet had the lowest gizzard weight (P〈0.05). Chromium turnover time (minutes) in the each segment and entire GI tract of chicks was not influenced by the high fiber diet or cellulase.

• Journal of the Korean Magnetics Society
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• v.3 no.1
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• pp.48-55
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• 1993

We report the photoemission (PES) studies for the Co/Pd multilayter. The Co 3d PES spectrum of Co/Pd exhibits two interesting features, one near the Fermi energy, $E_{F}$, and another at ~2.5 eV below $E_{F}$. The Co 3d peak near $E_{F}$ of Co/Pd is much narrower than that of the bulk Co, consistent with the enhanced Co magnetic moment in Co/Pd compared to that in the bulk Co. The Co 3d feature at ~-2.5 eV resembles the Pd valence band structures, which suggests a substantial hybridization between the Co and Pd sublayers. The Co 3d PES spectrum of Co/Pd is compared with the existing band structures, obtained using the local spin density functional calculations. A reasonable agreement is found concerning the bandwidth of the occupied part of the Co 3d band, whereas a narrow Co 3d peak near $E_{F}$ seems not to be described by the band structure calculations.