• Journal of Nutrition and Health
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• v.39 no.4
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• pp.323-330
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• 2006

Peripheral insulin resistance in obese/type II diabetes animals results from an impairment of insulin-stimulated glucose uptake into skeletal muscle. Insulin stimulate the translocation of GLUT4 from intracellular location to the plasma membrane. Soluble N-ethylmaleimide-sensitive factor attachment protein receptors (SNAREs) is implicated in mediation of fusion of GLUT4-containing vesicle with the plasma membrane. Present study investigated regulatory effects of Rhodiola sachalinensis administration and exercise training on the expression of GLUT4 protein and SNAREs protein in skeletal muscles of obese Zucker rats. Experimental animals were randomly assigned into one of five groups ; lean control(LN), obese control(OB), exercise-treated(EXE), Rhodiola sachalinensis-treated(Rho), combine of Rho & EXE (Rho-EXE). All animals of exercise training (EXE, Rho-EXE) performed treadmill running for 8 weeks, and animals of Rho groups (Rho, Rho-EXE) were dosed daily by gastric gavage during the same period. After experiment, blood were taken for analyses of glucose, insulin, and lipids levels. Mitochondrial oxidative enzyme (citrate synthase, CS ; $\beta$-hydroxyacyl-CoA dehydrogenase, $\beta$-HAD) activity were analysed. Skeletal muscles were dissected out for analyses of proteins (GLUT4, VAMP2, syntaxin4, SNAP23). Results are as follows. Exercise and/or Rhodiola sachalinensis administration significantly reduced body weight and improved blood lipids (TG, FFA), and increased insulin sensitivity. Endurance exercise significantly increased the activity of mitochondrial enzymes and the expression of GLUT4 protein, however, administration of Rhodiola sachalinensis did not affect them. The effect of exercise and/or Rhodiola sachalinensis administration on the expression of SNARE proteins was unclear. Our study suggested that improvement insulin sensitivity by exercise and/or Rhodiola sachalinensis administration in obese Zucker rats is independent of expression of SNARE proteins.

• The Journal of Korean Academy of Orthopedic Manual Physical Therapy
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• v.29 no.1
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• pp.33-39
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• 2023

Background: Most Pilates programs for older adults have been based on mat Pilates, and there has been limited research on Pilates with mini-balls. Therefore, this study aims to compare the effects of Pilates with mini-balls and mat Pilates interventions on strength, total body endurance, flexibility, and dynamic equilibrium to determine the differences. Methods: The elderly aged 65 or older living in Gyeongsan, Daegu, were divided into two groups, and the experimental group (n=10) conducted a Pilates exercise program using mini balls for 12 weeks, and the control group (n=10) conducted a mat Pilates exercise program for 12 weeks without mini balls. Strength, endurance, flexibility, and dynamic equlibrium were measured as a pre-test, and post-test was performed in the same way after 12 weeks of application. Results: Comparing the mini-ball Pilates group to the mat Pilates group, there was a significant difference (p<.05) in the 'chair sit and reach' after the intervention. In the within-group comparison, there was a significant increase (p<.05) in 'arm curl right', '30-second chair stand', '2-minute walk', 'back scratch', 'chair sit and reach', and '2.44m up and go' in the experimental group using the mini-ball Pilates program. Mat Pilates program significantly increased the within-group comparisons in '30-second chair stand' and 'chair sit and reach' (p<.05). Conclusion: It is suggested that mini-ball Pilates has a positive effect on the senior fitness and will be a good exercise method for using it as an exercise program for the elderly in the future.

• Journal of the Korea Society of Computer and Information
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• v.29 no.8
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• pp.93-101
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• 2024

The purpose of this study was to the effects of a cervical stabilization exercise using pressure biofeedback intervention on suboccipital muscle tone, deep neck flexor muscle endurance, and craniovertebral angle in college students with forward head posture. The subjects of the study were selected as BCSEG(n=12) and CG(n=12), and the intervention was performed for 50 minutes, 3 times a week for 8 weeks. The results of the study showed that after biofeedback neck stabilization exercises, the suboccipital muscle significantly decreased in stiffness and muscle tone in the BCSEG(p<.01), and the deep neck flexors significantly increased in muscle endurance(p<.01) and craniovertebral angle(p<.01). The results of the cervical stabilization exercises with biofeedback are thought to improve cranio- vertebral angle by improving muscle function of the suboccipital muscles and deep neck flexors, which cervical stabilization exercises with biofeedback may be suggested as an intervention to improve FHP.

• Journal of Korean Academy of Nursing
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• v.37 no.4
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• pp.568-575
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• 2007

Purpoes: The study was done to investigate the effects of an exercise program on body composition, cardiopulmonary function and physical fitness in obese children. Methods: Thirty nine children in grades 4, 5, and 6 in elementary school were employed: experimental group(20) and control group(19). The subjects in the experimental group participated in an exercise program for 8weeks, thirty five minutes per session, four times per week. This data was analyzed by ANCOVA and paired t-test. Result: The Height(F=2.615, p=0.027) of the experimental group was significantly different from the control group. Also, in the experimental group, there were significant differences of height(t=4 79, p=0.000), cardiac rate(t=-6.461, p=0.000), body mass index(t=-2.13 p=0.046), muscle strength(t=3.48, p=0.003), and muscle endurance(t=3.20, p=0.005). Otherwise, in the control group, there were significant differences of weight(t=2.27, p=0.036), waist-hip ratio(t=3.16, p=0.005), and muscle endurance(t=-2.38, p=0.030). Conclusion: Jumping rope improved the body composition, cardiopulmonary function, and physical fitness for obese children.

• Journal of Nutrition and Health
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• v.33 no.1
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• pp.13-22
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• 2000

Effects of high fat diet and/or endurance exercise training on hepatic total and phospholipid(PL) fatty acid compositions were evaluated in rats fed one of the following diets for 31 days. control diet(CD, 5 wt% corn oil) or high fat diet(HFD, 35 wt% corn oil). Half of the rats in each group were exercise-trained regularly on a treadmill for 90 minutes/day during the entire feeding period. Total and PL fatty acid compositions of hepatic lipid extracts were determined by a gas-liquid chromatograph),. Endurance exercise training did not change the daily food intake, but significantly reduced body weight gain and feed efficiency ratio of rats, which were most prominent in animals fed HFD. Exercise training did not significantly change the percentages of ∑saturated fatty acids (SFA) and ∑polyunsaturated fatty acids(PUEA), but decreased the percentage of ∑monounsaturated fatty acids(MUFA) in hepatic total fatty acids, which might be associated with the decrease in (equation omitted) 9-desaturation index of hepatic total fatty acid metabolism. Exercise training significantly lowered the percentages of 16 : 0 and 22 : 5$\omega$3, and increased the percentages of 20 : 1 and 20 : 3$\omega$3 in both total and PL fatty acid compositions in rat liver. Both total fatty acid and PL fatty acid compositions of rat liver responded more sensitively to changes in dietary fat content than to endurance exercise training in this study. Feeding HFD, whoch contains high level of linoleic acid(LA, 18 : 2$\omega$6), significantly decreased the percentages of ∑SFA and $\Sigma$MUFA, and increased the percentages of ∑PUFA and ∑$\omega$6 fatty acids of hepatic total fatty acids. Hepatic total fatty acid composition was affected by dietary fat content and dietary fatty acid composition more sensitively than those found in hepatic PL fatty acid composition. HFD significantly decreased most of desaturation indices, while exercise training significantly decreased elongation index(20 : 5$\omega$3⇒22 : 5$\omega$3) of hepatic total and PL fatty acid metabolism in rats. (Korean J Nutrition 33(1) : 13-22, 2000)

• Journal of the Korean Society of Food Science and Nutrition
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• v.41 no.10
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• pp.1409-1416
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• 2012

This study examined the effects of four herbal sports drinks containing Prunus mume, Liriope platyphylla, and Acanthopanax senticosus fruit extracts on body fat and endurance of rats trained by a progressive loaded exercise program. Forty male Sprague-Dawley rats (6 weeks old) were divided into five groups and fed experimental diets for 6 weeks according to the following protocol: C, exercise-trained control group (n=8); A, exercise group with Acanthopanax senticosus extract (n=8); L, exercise group with Liriope platyphylla extract (n=8); PA, exercise group with Prunus mune fruit extract plus Acanthopanax senticosus extract (n=8); PL, exercise group with Prunus mune fruit extract plus Liriope platyphylla extract (n=8). Endurance was measured by a progressive loaded exercise test using a treadmill. PA and PL supplementation significantly extended time to exhaustion compared to the control group (p<0.05). Further, the four herbal sports drinks all significantly reduced epididymal and interscapular white adipose tissue weights compared to the control group (p<0.05). Plasma triglyceride concentration was significantly lower in the A group compared to the control group. Plasma free fatty acid concentration was higher in the A group compared to the control group. On the other hand, Acanthopanax senticosus fruit extract supplementation tended to reduce the plasma glucose concentration compared to the control group. PA and PL supplementation significantly increased gastrocnemius muscle LDH activities compared to the control group (p<0.05). These results show that sports drink containing Acanthopanax senticosus improved endurance capacity, plasma lipids, and glucose concentrations. Sports drink with Prunus mume and Liriope platyphylla or Acanthopanax senticosus was synergistically improved endurance.

• Journal of Society of Preventive Korean Medicine
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• v.18 no.2
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• pp.115-123
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• 2014

Objective : The objective of this study is to develop a Qigong exercise program to reinforce musculoskeletal system of seniors appropriate for physical strength and conditions of seniors aged 65 years or above based on health Qigong exercise of oriental medicine. Method : Qigong exercise motions that can improve strength, muscular endurance, flexibility, and cardiovascular endurance of seniors were developed by primarily performing literature review of Qigong experts on the fields like oriental medicine, Qigong exercise, physical education and health science and secondarily using motion training for increased validity of motions. Results : The Qigong exercise program for musculoskeletal system of seniors was designed with 12 motions repeated 8 times and 20 minutes per session, including shoulder exercises (alternate turning of left and right shoulders, turning both arms back and forth, holding and lifting elbow to put it aside), waist exercises (wrapping the head with hands to bow, twisting waist while looking at the tip of hand, large spinning of ball, putting hands together to pull back), and knee exercises (going up a down while lifting a rock, balancing the body while lifting a knee, lifting and spreading knees while drawing circle with arms, raising both arms to the side while lifting heels, breathing). Conclusion : Once the effects of Qigong exercise for musculoskeletal system of seniors developed in this study are tested, the program is expected to contribute to development of Qigong exercise, a core part of oriental medicine health improvement project.

• Journal of Physiology & Pathology in Korean Medicine
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• v.31 no.4
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• pp.238-245
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• 2017

This retrospective observational study was aimed to evaluate that Daoyin Exercise therapy improves the symptoms related to lumbar disc herniation. We analyzed the medical records of 7 patients, who satisfied with inclusion and exclusion criteria. The subjects of the study were the patients who were prescribed Daoyin Exercise Therapy and Korean medical treatments for lumbar intervertebral disc herniation at Dunsan Korean Medicine Hospital of Daejeon University from July 25th, 2016 to March 31th, 2017. The effects of Daoyin Exercise Therapy was evaluated by comparing before and after taking Daoyin Exercise Therapy through 0-10 Numeric Rating Scale(NRS), Roland & Morris Disability Questionnaire(RMDQ), Trunk Extension Flexion(TEF) Program, EuroQol five Demension Questionnaire(EQ-5D, EQVAS) of the symptoms including lower back pain. The Daoyin Exercise Therapy combined with Korean medicine treatment reduced NRS($3.357{\pm}3.038$) and RMDQ($9.50{\pm}6.364$), and improved Muscle endurance($44.429{\pm}45.136$), EQ-5D($0.09{\pm}0.12$) and EQVAS($6.571{\pm}19.260$) of the 7 patients without side effects. These results implied that Daoyin Exercise Therapy might helps to improve symptoms of patients with lumbar disc herniation by reducing the symptoms of lower back pain and improving muscle endurance, quality of life, strength enhancement and core muscles.

• Journal of Nutrition and Health
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• v.37 no.10
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• pp.881-887
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• 2004

Elevated plasma homocysteine is an independent risk factor for the development of cardiovascular disease. Exercise is generally believed to reduce the plasma homocysteine levels and therefore, being beneficial for cardiovascular disease (CVD). However, there is a possibility that athletes undergoing strenuous training and competition which increase oxidative stress may suffer from increased plasma homocysteine levels. The purpose of this study was to investigate the influence of endurance training on the plasma concentrations of B vitamins and homocysteine in 23 male adolescent field hockey players. Data collection and blood sampling was performed during the training period and non-training period. Following the training period, significant changes in energy and vitamin B6 intakes were observed in these subjects. Plasma vitamin B2, pyridoxal phosphate (PLP) and homocysteine levels were significantly higher during the training period than non-training period, whereas no difference was observed in plasma folate and vitamin B12 levels. Positive correlation was observed between plasma folate and folic acid intakes. When energy, B vitamin intakes were adjusted there was a significant negative correlation between plasma homocysteine levels and plasma riboflavin, folate and vitamin B12 levels. In conclusion, it is suggested that athletes with oxidative stress by strenuous exercise may need B vitamins since riboflavin, folic acid and vitamin Bl2 were shown to be negatively correlated with plasma homocysteine in athletes during the training period.

• Journal of the Korean Society of Physical Medicine
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• v.17 no.1
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• pp.63-74
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• 2022

PURPOSE: This study aimed to compare the effects of manual therapy with stabilization exercises to manual therapy alone, on neck pain and body functions in patients with chronic mechanical neck pain. METHODS: Twenty patients with chronic mechanical neck pain were recruited and randomly allocated into two groups. A control group(n = 10) was given the manual therapy alone and an experimental group(n = 10) was given the manual therapy with stabilization exercises. The intervention was carried out 3 days per week for 4 weeks. The cervical resting pain, the most painful motion pain, craniocervical flexor endurance, forward head posture and neck disability index were used to assess participants at baseline and after 4 weeks. RESULTS: A comparison of the parameters before and after the intervention showed that both groups experienced significant improvements in the resting pain, the most painful motion pain, craniocervical flexor endurance, and forward head posture except for the forward head posture in the control group. A comparison of the parameters between the groups did not show a significant difference. CONCLUSION: The results of this study suggest that the combined intervention of manual therapy with stabilization exercise does not seem to be more effective than manual therapy alone for improving neck pain, craniocervical flexor endurance, forward head posture, and the neck disability index in patients with chronic mechanical neck pain.