• Title/Summary/Keyword: End-products

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Anti-inflmmatory Effects of Scutellaria baicalensis Georgi Water Extract in the THP-1 Cells Activated by Advanced Glycation End Products (황금 물추출물의 당화종말산물로 유도한 THP-1 세포의 염증반응 억제효과)

  • Park, Pyeong-Beom;Kim, Min-Jun;Shin, Kyoung-Ho;Lee, Kwang-Gyu;Lee, Chang-Hyun;Lee, Sang-Ryong;Ha, Ki-Tae;Jeong, Han-Sol
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.26 no.3
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    • pp.273-280
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    • 2012
  • Scutellaria baicalensis Georgi, which has been known to be able to clear away heat and remove dampness, was used for febrile disease. It is now clear that Advanced glycation end products (AGEs) play major roles in the pathogenesis of diabetic complications such as atherosclerosis. In this study, we examined whether Scutellaria baicalensis Georgi suppress the AGE mediated inflammatory responses in the THP-1 cells. AGE treatment increased the gene expression of pro-inflammatory cytokines such as tumor necrosis factor-${\alpha}$ (TNF-${\alpha}$), interleukin-$1{\beta}$ (IL-$1{\beta}$), monocyte chemotactic protein-1 (MCP-1) and cyclooxygenase-2 (COX-2). Reverse transcriptase-polymerase chain reaction and Western blot analysis revealed that S. baicalensis had inhibitory effects on the expression of pro-inflammatory genes and protein levels in AGE-treated THP-1 cells. S. baicalensis had also reduced the production of ROS in the AGE-treated THP-1 cells. These results suggest that S. baicalensis has inhibitory effects for the development of diabetic vascular complication.

Screening of Herbal Medicines from China and Vietnam with Inhibitory Activity on Advanced Glycation End Products (AGEs) Formation (VIII) (중국.베트남 약용식물의 최종당화산물 생성저해활성 검색(VIII))

  • Choi, So-Jin;Song, Yoo Jin;Kim, Young Sook;Kim, Joo Hwan;Hang, Sun;Tran, The Bach;Kim, Jin Sook
    • Korean Journal of Pharmacognosy
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    • v.43 no.4
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    • pp.338-344
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    • 2012
  • Advanced glycation end products (AGEs) have been postulated to play a central role in the development of diabetic complications. A variety of different agents that inhibit AGEs have been under investigation. In this study, 62 herbal medicines from China and Vietnam have been investigated with an in vitro evaluation system using AGEs formation inhibitory activity. Of these, 5 herbal medicines ($IC_{50}$ < $5{\mu}g/ml$) were found to have significant AGEs formation inhibitory activity. Particularly, herbal medicines Albizia odoratissima (twigs and leaves), Rhododendron spinuliferum (twigs and leaves), Dioscorea cirrhosa (stems and leaves), Illicium verum (stems and leaves) and Aglaia perviridis (stems and leaves), showed more potent inhibitory activity (approximately 16-26 fold) than the positive control aminoguanidine ($IC_{50}=76.47{\mu}g/ml$).

The Direction of the Fisheries Policy in Korea after the End of the Uruguay Round of Global Trade Talks (UR타결후의 한국수산정책의 방향)

  • 김경호
    • The Journal of Fisheries Business Administration
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    • v.24 no.2
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    • pp.1-16
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    • 1993
  • Because of the radical changes in the domestic and foreign economic circumstances Koreaa fisheries is confronted with difficulties. Along the end of the UR marine products of other nations are rushing into Korea. Also migration of labor to other industries and rise of wage level in Korean fisheries deteriorate managerial conditions. But in Korea which has little natural resourses fisheries is still more important. That is \circled1 creating job opportunites \circled2 increase of income \circled3 supply of foodstuffs and animal protein \circled4 acquisition of foreign currency \circled5 enlargement of domestic market for industrial products \circled6 development of other interrelated industries \circled7 rational use of domestic resourses \circled8 diversification of population and production activites \circled9 contribution to balanced growth of national economy by the developing regional economy. These roles of fisheries in national economy mentioned above are to be excuted forward. In spite of the radical change in the economic circumstances at the end of the UR fisheries if crucial in Korea as a industry. For this our fisheries is to be made to compete with foreign fisheries. Through the cheap price and high quality our fisheries must be came to compete with foreign fisheries and meet the people's needs for marine products. For this it is necessary to maintain high productivity and competitive power. Now with the exception of a portion of the deep - sea fishing, our fisheries is generally paltry, Especially inshore fishery which is the main stock in our fisheries is very paltry and so productivity and competetive power are very low. So to develop our fisheries which has s comparative disadvantage active polices that follows below are to be promoted on a large scale. \circled1 improvement of structure \circled2 augmentation of productivity in fishing ground by making fisheries resourses \circled3 enlargement of finantial and monetary assistance \circled4 effective administration of fisheries cooperative union \circled5 activation of R&D etc These polices which need to be scientific and comprehensive are very valuable. Especially without making fishieries resources we cannot expect economy of scale, promotion of productivity and development of fisheries. And we do also endeavour to gather the results of the study and investigation about fisheries domestic and foreign and do ceaselessly put these to practical use systimatically.

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A Study on a Clothing Purchase Process Model Using Images of Clothing Merchandise (의류상품 이미지에 의한 의복구매과정 모형 연구)

  • 정은영;이신재
    • Journal of the Korean Society of Clothing and Textiles
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    • v.18 no.5
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    • pp.749-764
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    • 1994
  • It was assumed that a consumer forms images of all the factors related to clothing merchandise such as trademarks, stores, products and prices that he/she perceives in the market and those images deforming his/her preference for a particular piece of clothes and intention of purchase. Under this assumption, this research was designed to find out important factors of clothes that help a consumer form an image of the clothes, among other attributes of the merchandise, and how this image is related to the existing extraneous variables such as the trademark image, the consumer's self image, the price, etc. in leading the consumer to purchase the particular clothes in the end. In the empirical research, a preliminary survey was conducted to select brands of womenswear that were suitable for this study and as the result, 16 brands were chosen. Then one trademark, one store and two products from each of the 16 brands were selected. With these materials, 32 stimulus sheets were prepared, and each of them was composed of 3 photos of a brand's catalog and logo, the interior of a selected store that carried products of the brand, and formal suits selected from each brand's spring/summer 1993 collections. Subjects were 460 women in the age groups of 20-50s who live in Seoul Metropolitan area. Each of the subjects was provided with a survey questionnaire and 16 stimulus sheets. The main findings of this research prove that consumers follow a certain selection process model when they purchase clothes: consumers, first, from images of merchandise based on the trademarks, stares, and products and those formed images work il.: medium variables and in the end they help the consumers decide whether to buy the products.

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An Instance of Selecting Retention Chemicals Based on Simultaneous Analysis of Retention, Drainage and Formation of RDA (Retention and Drainage Analyzer) Sheets (보류, 탈수, 지합을 종합적으로 고려한 Retention and Drainage Analyzer (RDA) 활용 보류향상제의 선정사례)

  • Jeon, Chang-Hoon;Ryu, Jeong-Yong;Song, Bong-Keun;Seo, Young-Bum;Chung, Sung-Hyun
    • Journal of Korea Technical Association of The Pulp and Paper Industry
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    • v.42 no.3
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    • pp.7-13
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    • 2010
  • KOptimization and control of wet-end process provide a key solution to improve paper quality and production efficiency at the same time. Wet-end of paper machine is to determine three important influencing factors of papermaking i.e., retention, drainage and formation. Good formation of paper could be made at the cost of deteriorated retention or drainage. In the same manner increase of retention aid could cause the bad formation of paper. It is very important to find a proper retention chemical which may satisfy one of three factors without the sacrifice of other two. Laboratory scale analyzing or screening chemical additives of wet-end was reported in this study based on RDA sheet molding. Different from the conventional test method, simultaneous consideration of three important wet-end properties could be made by RDA and consequently more reliable prediction of actual paper machine wet-end could be expected.

Dynamic Analysis of the Effect of Network Externality in Vertically Differentiated Market (수직적으로 차별화된 시장 하에서 망외부성이 미치는 영향에 대한 동태적 분석)

  • Cho, Hyung-Rae;Rhee, Minho
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.42 no.2
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    • pp.1-8
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    • 2019
  • Network externalities are essentially dynamic in that the value consumers feel about a product is affected by the size of the existing customer base that uses that product. However, existing studies on network externalities analyzed the effects of network externalities in a static way, not dynamic. In this study, unlike previous studies, the impact of network externalities on price competition in a vertically differentiated market is dynamically analyzed. To this end, a two-period duopoly game model was used to reflect the dynamic aspects of network externalities. Based on the game model, the Nash equilibria for price, sales volume, and revenue were derived and numerically analyzed. The results can be summarized as follows. First, if high-end product has strong market power, the high-end product vendor takes almost all benefits of the network externality. Second, when high-end product has strong market power, the low-end product will take over most of the initial sales volume increase. Third, when market power of high-end product is not strong, it can be seen that the effects of network externalities on the high and low-end products are generally proportional to the difference in quality. Lastly, if there exists a strong network externality, it is shown that the presence of low-end product can be more profitable for high-end product vendor. In other words, high-end product vendor has incentive to disclose some technologies for the market entrance of low-end product, even if it has exclusive rights to the technologies. In that case, however, it is shown that the difference in quality should be maintained significantly.

Offline and Online Channel Sales of Existing Products and New Products: Findings from Experience Goods (오프라인과 온라인 채널상의 기존제품과 신제품의 판매 성과: 경험재에 대한 시계열 분석을 중심으로)

  • Kim, Jeeyeon;Kim, Mingyung;Choi, Jeonghye
    • Knowledge Management Research
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    • v.16 no.4
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    • pp.109-132
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    • 2015
  • We examine offline and online channel sales of experience goods, and compare and contrast the sales patterns of existing products and new products between channels. To this end, we obtain the channel-specific time-series sales data from the leading company selling beauty products, both offline and online. By applying the Vector Autoregressive Model, we empirically find out how the relationship between existing products and new products changes between the shopping channels. Our empirical findings are as follows. First, the sales effects from existing products to new products are significantly positive at both offline and online channels, and this positive effect is greater in the offline channel than in the online channel. Second, the influence of new products on existing products is more positive in the offline channel than in the online channel. Third, the impact of existing products sales on new products sales is greater than that of new products on existing products. Lastly, the inertia effect, the effect within the same shopping channel and the same selling product, is significantly positive in the offline channel but not in the online channel, and this asymmetric inertia effect emerges as we focus on experience goods. Moreover, the impulse response function analysis provides the three important implications. First, companies should pay attention to the same channel but different types of products. Second, the offline channel is more vulnerable to market shock than the online channel. Third, new products sales vary by existing products sales to the greater extent, compared to the opposite relationship. We believe our study contributes theoretically and practically to the fields of marketing and knowledge management.

ON THE TOPOLOGY OF THE NONABELIAN TENSOR PRODUCT OF PROFINITE GROUPS

  • Russo, Francesco G.
    • Bulletin of the Korean Mathematical Society
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    • v.53 no.3
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    • pp.751-763
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    • 2016
  • The properties of the nonabelian tensor products are interesting in different contexts of algebraic topology and group theory. We prove two theorems, dealing with the nonabelian tensor products of projective limits of finite groups. The first describes their topology. Then we show a result of embedding in the second homology group of a pro-p-group, via the notion of complete exterior centralizer. We end with some open questions, originating from these two results.

Petrochemical Industry Overview

  • Won, Ho-Yeon
    • Proceedings of the Polymer Society of Korea Conference
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    • 2006.10a
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    • pp.141-141
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    • 2006
  • Petrochemicals contain a wide variety of monomers and their derivatives which are used in the production of plastics, fibers and synthetic rubber. Until now, petrochemicals have had a dramatic impact on our food, clothing, shelter and leisure because they are the least expensive, most readily available, and can be processed most easily into the end use products. Petrochemical industry, which is known as one of the typical cycle profitability businesses, is now moving downward. In order to overcome the anticipated loss of profit, petrochemical companies are making an effort to offer a value-added upgrading to conventional products. This lecture will discuss a few of issues on the current status and prospect of petrochemical industry.

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A Study on the Quality Improvement of Special Printed Wire Board Using Scale Factor (치수인자를 이용한 특수 인쇄 배선기판의 품질향상에 관한 연구)

  • Chun, Young Ho
    • Journal of Korean Society for Quality Management
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    • v.22 no.4
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    • pp.152-159
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    • 1994
  • A study of improvement of printing accuracy of special PCB has been carried out by applying the corrected data of laminate dimensional variation to real products. The result of this study improved the accuracy of product by decreasing the deviation between design specifications and end products. This paper will be useful when PCB manufacturers using paper phenol laminates make preparation for customer's needs, more complicated specifications. And so, it will be successful for image renovation of any company by assuring the reliabilities to customers.

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