• 한국언론정보학보
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• 제41권
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• pp.337-382
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• 2008

직장 생활을 하는 여성들이 점점 늘어나고 있다. 그러나 직장 여성들에 대한 담론은 부족한 편이며, 성과 중심이나 불평등과 같은 편중된 시각이 대부분이다. 여성들의 갈등 경험은 직장 내에서 발생할 수 있는 상호 작용의 다양한 측면을 내포하고 있기 때문에 여성들이 처해있는 직장 생활의 현실을 여실히 보여줄 수 있는 좋은 사례이다. 또한 이 연구는 갈등 연구에 적합한 연구 방법의 하나로 현상학적 연구를 제안하고 있다. 기존의 커뮤니케이션을 중심으로 한 갈등 연구들이 갈등대처 유형과 같은 변인을 밝히는데 치중하였다는 한계를 가지기 때문이다. 갈등은 무엇보다 맥락에 상당 부분 의존하며, 역동적인 상호 작용 속에서 이뤄지기 때문에 구체적이며 총체적인 해석이 무엇보다 필요하다. 이러한 관점에서, 본 논문에서는 여성들이 직장 내에서 겪고 있는 갈등 경험을 현상학적 연구방법으로 연구하였다. 그 결과, 다음의 여덟 가지 주제를 확인할 수 있었다. 첫 번째 주제는 '불합리한 상황', 두 번째 주제는 '위계적 질서'이다. 세 번째 주제는 '갈등에 대한 부정적인 생각'이며, 네 번째 주제는 '여자와 남자의 차이 인식', 다섯 번째 주제는 '관계의 문제를 중시함'으로 나타났다. 여섯 번째 주제는 '소극적 대처 행동'이며, 일곱 번째 주제는 '공격적인 대응', 마지막 여덟 번째 주제는 '적극적으로 갈등에 대처'였다. 아울러 이 같은 결과가 갖는 함의와 향후 연구를 위한 제언이 제시되었다.

• Asian Pacific Journal of Cancer Prevention
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• 제14권6호
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• pp.3941-3944
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• 2013

Background: The use of preoperative chemoirradiation is the commonest treatment strategy employed in Malaysia for locally advanced rectal cancer. We need to determine the local control and survival rates for comparison with established rates in the literature. Materials and Methods: This retrospective study analyzed all newly diagnosed patients with rectal adenocarcinoma who underwent long course preoperative radiotherapy (RT) at the Department of Radiotherapy and Oncology, Kuala Lumpur Hospital (HKL) between $1^{st}$ January 2004 and $31^{st}$ December 2010. The aim of the study was to determine the radiological response post radiotherapy, pathological response including circumferential resection margin (CRM) status, 3 years local control, 3 years overall survival (OS) and 3 years disease free survival (DFS). Statistical analysis was performed using the SPSS software. Kaplan-Meier and log rank analysis were used to determine survival outcomes. Results: A total of 507 patients with rectal cancer underwent RT at HKL. Sixty seven who underwent long course preoperative RT were eligible for this study. The median age at diagnosis was 60 years old with a range of 26-78 years. The median tumour location was 6 cm from the anal verge. Most patients had suspicion of mesorectum involvement (95.5%) while 28.4% of patients had enlarged pelvic nodes on staging CT scan. All patients underwent preoperative chemo-irradiation except for five who had preoperative RT alone. Only 38 patients underwent definitive surgery (56.7%). Five patients were deemed to be inoperable radiologically and 3 patients were found to have unresectable disease intraoperatively. The remaining 21 patients defaulted surgery (31.3%). The median time from completion of RT to surgery was 8 weeks (range 5.6 to 29.4 weeks). Fifteen patients (39.5%) had surgery more than 8 weeks after completion of RT. Complete pathological response was noted in 4 patients (10.5%). The pathological CRM positive rate after RT was 18.4%. With a median follow-up of 38.8 months, the 3 year local control rate was 67%. The 3 years rate for CRM positive (<2 mm), CRM clear (>2 mm) and pCR groups were 0%, 88.1% and 100% respectively (p-value of 0.007). The 3 year OS and DFS were 57.3% and 44.8% respectively. Conclusions: In conclusion, the approach of long course preoperative chemoirradiation for rectal cancer needs to be re-examined in our local setting. The high rate of local recurrence is worrying and is mainly due to patient defaulting post-preoperative chemoirradiation or delayed definitive surgery.

• 전자공학회논문지CI
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• 제43권6호
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• pp.43-51
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• 2006

본 논문은 영한 기계번역을 위한 예제기반 기계번역에서 예제 문장의 비교를 위한 척도에 관한 것으로 주어진 질의 문장과 가장 유사한 예제 문장을 찾아내는데 사용되는 유사성 척도를 제안한다. 제안하는 척도는 편집거리 알고리즘에 기반을 둔 것으로 표면어가 일치하지 않는 단어에 대해 기본적으로 단어의 표제어 정보와 품사 정보를 이용하여 유사도를 계산한다. 편집거리 척도는 비교 단위의 순서에 의존적이기는 하지만 순서만 일치하면 동일한 유사성 기여도를 갖는 것으로 판단하기 때문에 완전 문맥을 반영하지는 못한다. 따라서 본 논문에서는 완전 문맥 반영을 위해 추가적으로 이들 정보 외에 일치하는 단위 정보를 갖는 연속된 단어들에 대해 연속 정보를 반영한 문맥 가중치를 제안한다. 또한 비유사성 정도를 의미하는 척도인 편집거리 척도를 유사성 척도로 변경하고, 문맥 가중치가 적용된 척도를 문장 비교에 적용하기 위하여 정규화를 수행하며, 이를 통하여 유사도에 따른 순위를 결정한다. 또한 언어적 정보를 이용한 기존 방법류들에 대한 일반화를 시도하였으며, 문맥 가중치가 적용된 척도의 우수성을 증명하기 위해 일반화된 기존 방법류들과의 비교 실험을 수행하였다.

• 한국콘텐츠학회논문지
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• 제18권5호
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• pp.230-240
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• 2018

본 연구는 산후 1개월 및 6개월 완전모유수유율을 파악하고 이에 영향을 미치는 요인을 파악하기 위해 수행하였다. 본 연구는 서술적 조사연구로, 연구자료는 2015년 전국 출산력 및 가족보건복지실태 조사 원시 자료를 이용하였다. 연구대상자는 조사 완료된 기혼여성 중 2013년 1월부터 조사시점에 추산 후 6개월이 경과한 2015년 2월 사이에 자녀를 출산한 1,839명이었다. 자료분석은 SPSS 25.0 프로그램을 이용하여 기술 통계분석, 카이제곱분석 및 다중로지스틱분석을 실시하였다. 연구결과 분만 후 1개월 및 6개월 완전모유수유율은 각각 54.0%, 9.4%로 월령이 증가함에 따라 완전모유수유율이 감소하였다. 산후 1개월 완전모유수유율에 영향을 미치는 요인은 산모의 나이, 아기의 출생순위, 분만형태, 분만 후 1시간 이내 모유수유 여부였으며, 산후 6개월 완전모유수유율에 영향을 미치는 요인은 산모의 나이, 거주지역, 아기의 출생순위, 산후 1개월 완전모유수유 여부였다. 본 연구결과 완전모유수유에 영향을 미치는 요인은 출산 후 시기에 따라 다른 것으로 확인되었다. 따라서 완전모유수유율 향상을 위해 출산 후 각 시기별 완전모유수유에 영향을 주는 요인을 고려한 맞춤형 중재가 필요하다.

• Asian Pacific Journal of Cancer Prevention
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• 제16권11호
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• pp.4685-4690
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• 2015

Purpose: To evaluate the correlation between cosmetic outcome (CO), body image, and quality of life in post breast-conserving therapy (BCT) women. Materials and Methods: This cross-sectional study concerned one-year post-completed BCT Thai women. The data included subjective and objective CO with a questionnaire covering demographic and clinical data, anti-hormonal treatment status, Eastern Cooperative Oncology Group (ECOG) performance status, Self-Reported Cosmetic Outcomes (SRCO), Self-Reported Breast Symmetry (SRBS), Body Image Scale (BIS), and the Functional Assessment of Cancer Therapy with Breast Cancer subscale (FACT-B). Participants had breast photographs taken for the evaluation of objective cosmetic outcome (OCO) after breast cancer conservation treatment. The relationship between CO and FACT-B was tested using Spearman's rank correlation Results: A total 127 participants volunteered for the study. The participant characteristics were age 52(${\pm}9$), Buddhist 87%, married 65%, body mass index 25.0(${\pm}4.6$), breast cup size A-C 91%, college educated 60%, employed 66%, ECOG 0-1 95%, tumor size less than or equal to 2 cm 55%, no lymph node metastasis 98%, and taking tamoxifen 57%. Two percent of the participants regretted their decision to undergo BCT. The SRCO was excellent in 2%, good in 68%, fair in 30%, and poor in 0%. For SRBS, rates were 17%, 58%, 24% and 1% for excellent, good, fair and poor cosmetic outcomes, respectively. The BCCT scores were excellent 24%, good 39%, fair 32%, and poor 6%. The median total QOL score of the participants was 130 (93-144). There was no significant correlation between CO and FACT-B scores. Conclusions: The significance of CO for FACT-B in Thai women with breast cancer could not be assessed in detail because of a very low level of correlation. The results may be due to the effects of cultural background.

• Journal of Preventive Medicine and Public Health
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• 제38권2호
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• pp.208-214
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• 2005

Objectives: This study was performed to examine the factors affecting re-smoking in male workers. Methods: A self-administrated questionnaire survey was conducted during April 2003 to examine the smoking state of 1,154 employees of a company that launched a smoking cessation campaign in1998. Five hundred and eighty seven persons, who had stopped smoking for at least one week, were selected as the final study subjects. This study collected data on smoking cessation success or failure for 6 months, and looked at the factors having an effect on re-smoking within this period. This study employed the Health Belief Model as its theoretical basis. Results: The re-smoking rate of the 587 study subjects who had stopped smoking for at least one week was 44.8% within the 6 month period. In a simple analysis, the re-smoking rates were higher in workers with a low age, on day and night shifts, blue collar, of a low rank, where this was their second attempt at smoking cessation and for those with a shorter job duration (p<0.05). Of the cues to action variables in the Heath Belief Model, re-smoking was significantly related with the perceived susceptibility factor, economic advantages of smoking cessation among the perceived benefits factor, the degree of cessation trial's barrier of the perceived barriers factor, smoking symptom experience, recognition of the degree of harmfulness of environmental tobacco smoke and the existence of chronic disease due to smoking (p<0.05). In the multiple logistic regression analysis for re-smoking, the significant variables were age, perceived susceptibility for disease, economic advantages due to smoking cessation, the perceived barrier for smoking cessation, recognition on the degree of harmfulness of environmental tobacco smoke, the existence of chronic disease due to smoking and the number of attempts at smoking cessation (p<0.05). Conclusion: From the result of this study, for an effective smoking ban policy within the work place, health education that improves the knowledge of the adverse health effects of smoking and the harmfulness of environmental tobacco smoke will be required, as well as counter plans to reduce the barriers for smoking cessation.

• Asian Pacific Journal of Cancer Prevention
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• 제13권3호
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• pp.1015-1018
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• 2012

Objective: To improve the diagnosis of primary gallbladder carcinoma (GBC) with/without hepatic metastases by analyzing our experience of different GBC treatment in our patients. Methods: A retrospective study was carried out to analyze the clinical data of the 139 patients with GBC who underwent hepatic resection in our unit from January 2003 to December 2007. Patients were divided into two groups according to whether they demonstrated hepatic invasion. Tumor presentation, surgical modes, and prognosis of each patient were retrospectively reviewed. Kaplan-Meier curves and log-rank tests were employed to compare the survival rates of those patients undergoing different surgical procedures. Results: Of the 139 patients, 46 were men and 93 were women with the male to female ratio of 1:2.0. Their ages were ranged from 35 to 86 years with a mean age of $62.8{\pm}10.4$ years. There were 73 patients complicated with hepatic invasion (group A), and no hepatic invasion occurred in the other 66 patients (group B). Compared with the group B, the patients with hepatic invasion suffered lower differentiation of tumor (p=0.000), more advanced Nevin staging (p=0.008) and poorer prognosis (p=0.013). Radical resection were more frequently performed in group B (75.76%) than in group A (45.20%) with better outcomes (p=0.000). Conclusion: GBC patients complicated with hepatic invasion had poorer prognosis than those without invasion in long-term follow-ups. Radical resection might result in a satisfied prognosis in patients without hepatic invasion, but appears less favorable than palliative resection in those who were complicated with hepatic invasion.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제23권6호
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• pp.521-530
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• 2020

Purpose: Malnutrition is a common feature in critically ill children. Enteral nutrition (EN) is the main strategy to nutritionally support critical ill children, but its use can be hindered by the development of intolerance. The study aimed to assess the effectiveness and safety of amoxicillin/clavulanate (A/C) to treat EN intolerance. Methods: We retrospectively evaluated patients admitted to the pediatric intensive care unit from October 2018 to October 2019. We conducted a case-control study: in the first 6 months (October 2018-April 2019) we implemented the nutritional protocol of our Institution with no drug, whereas in the second half (May 2019-October 2019) we employed A/C for 1 week at a dose of 10 mg/kg twice daily. Results: Twelve cases were compared with 12 controls. At the final evaluation, enteral intake was significantly higher than that at baseline in the cases (from 2.1±3.7 to 66.1±27.4% of requirement, p=0.0001 by Wilcoxon matched-pairs signed rank test) but not in the controls (from 0.2±0.8 to 6.0±14.1% of the requirement, p=NS). Final gastric residual volume at the end of the observation was significantly lower in the cases than in the controls (p=0.0398). The drug was well tolerated as shown by the similar safety outcomes in both cases and controls. Conclusion: Malnutrition exposes critically ill children to several complications that affect the severity of disease course, length of stay, and mortality; all may be prevented by early EN. The development of intolerance to EN could be addressed with the use of A/C. Future prospective clinical trials are needed to confirm these conclusions.

• Journal of Pharmaceutical Investigation
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• 제24권2호
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• pp.95-104
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• 1994

Inclusion complexes of ketoconazole(KT) with ${\alpha}^_$, ${\beta}^_$cyclodextrin(CD) and $dimethy1-{\beta}-cyclodextrin$ (CD) and $dimethy1-{\beta}-cyclodextrin(DM{\beta}CD)$ as nasal absorption enhancer were prepared in 1: 2 molar ratios by freeze-drying and solvent evaporation methods. In order to compare with the intrinsic absorptivity of KT in the jejunum(J) and the nasal cavity(N), the in situ simultaneous perfusion method was employed. The in situ recirculation study revealed that KT-CD inclusion complexes with the greater stability constant and the faster dissolution rate proportionally increased the absorption of KT in the J and N of rats. The rank order of apparent KT permeability$(P_{app}\;:\;cm/sec\;{\time}\;1O^{-5}{\pm}S.E.)$, corrected by surface area of absorption, was $5.10{\pm}0.3(N,\; KT-DM{\beta}CD)$ )> $4.13{\pm}0.4(N,\;KT-{\beta}-CD)$ )> $3.52{\pm}0.2(N,\;KT-{\alpha}-CD)$ )> $2.76{\pm}0.3(J,\; KT-DM{\beta}CD)$ )> $2.61{\pm}0.5(J,\;KT-{\beta}-CD)$ )> $2.42{\pm}0.4(J,\;KT-{\alpha}-CD)$ at pH 4.0. The in crease in permeability of $KT-DM{\beta}CD$ inclusion complex was 2.6 folds in the J and 4.5 folds in the N when the perfusing solution was changed from the buffer(pH 4.0) to saline. The absorption rate of $KT-DM{\beta}CD$ inclusion complex after nasal administration was more rapid than those of ketoconazole alone and $KT-DM{\beta}CD$ inclusion complex after oral administration to rats. In comparision with an oral administration of ketoconazole suspension in corn oil, the relative bioavailability was calculated 137.3% for the oral and 195.0% for nasal $KT-DM{\beta}CD$ inclusion complex in rats. The present results suggest that $KT-DM{\beta}CD$ inclusion complex may serve as a potential nasal absorption enhancer for the nasal delivery of ketoconazole.

• 임상간호연구
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• 제28권3호
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• pp.223-232
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• 2022

Purpose: The purpose of this study was to apply patient-engaged bedside handoffs in comprehensive care units, and to evaluate the effects of bedsides to nurses and patients. Methods: This study employed a cluster randomized cross-over design.Electrical Medical Record (EMR)-based handoffs and patient-engaged bedside handoffs were alternatively applied to 104 patients, who were assigned to a total of 30 clusters (nursing handoff teams) in 4 comprehensive care units at the S medical center in Seoul, and the patients evaluated each type of handoffs. A total of 139 nurses were also participated in the same units and evaluated each type of handoffs. Data were analyzed using t-test, Wilcoxon rank sum test, ANOVA, and Kruskal-Walls test. Results: The patient's satisfaction of the patient-engaged bedside handoffs was higher than that of the EMR-based handoffs (Z=-5.16, p<.001). On the other hand, the nurse's satisfaction of the patient-engaged bedside handoffs was significantly lower than that of the EMR-based handoffs (t=13.21, p<.001). There were no differences in length of the reporting time between two types of handoffs (t=-0.48, p=.634). Conclusion: Patient satisfaction with the patient-engaged bedside handoffs was higher than that of EMR-based handoffs, and nurses' satisfaction with the patient-engaged bedside handoffs was significantly lower than that of EMR-based handoffs. Future studies are needed regarding the impacts of patient-engaged bedside handoffs on the quality of healthcare by identifying the benefits of the handoffs.