• 한국축산식품학회지
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• 제34권1호
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• pp.106-114
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• 2014

Folic acid, one of the B group of vitamins, is an essential substance for maintaining the functions of the nervous system, and is also known to decrease the level of homocysteine in plasma. Homocysteine influences the lowering of the cognitive function in humans, and especially in elderly people. In order to determine the strains with a strong capacity to produce folic acid, 190 bacteria were isolated from various kinds of jeotgal and chungkuk-jang. In our test experiment, JA71 was found to contain $9.03{\mu}g/mL$ of folic acid after 24 h of incubation in an MRS broth. This showed that JA71 has the highest folic acid production ability compared to the other lactic acid bacteria that were isolated. JA71 was identified as Lactobacillus plantarum by the result of API carbohydrate fermentation pattern and 16s rDNA sequence. JA71 was investigated for its physiological characteristics. The optimum growth temperature of JA71 was $37^{\circ}C$, and the cultures took 12 h to reach pH 4.4. JA71 proved more sensitive to bacitracin when compared with fifteen different antibiotics, and showed most resistance to neomycin and vancomycin. Moreover, it was comparatively tolerant of bile juice and acid, and displayed resistance to Escherichia coli, Salmonella Typhimurium, and Staphylococcus aureus with restraint rates of 60.4%, 96.7%, and 76.2%, respectively. These results demonstrate that JA71 could be an excellent strain for application to functional products.

• Biomolecules & Therapeutics
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• 제28권2호
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• pp.145-151
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• 2020

Alzheimer's disease (AD) is a devastating neurodegenerative disease and a major cause of dementia in elderly individuals worldwide. Increased deposition of insoluble amyloid β (Aβ) fibrils in the brain is thought be a key neuropathological hallmark of AD. Many recent studies show that natural products such as polyphenolic flavonoids inhibit the formation of insoluble Aβ fibrils and/or destabilize β-sheet-rich Aβ fibrils to form non-cytotoxic aggregates. In the present study, we explored the structure-activity relationship of naturally-occurring biflavonoids on Aβ amyloidogenesis utilizing an in vitro thioflavin T assay with Aβ1-42 peptide which is prone to aggregate more rapidly to fibrils than Aβ1-40 peptide. Among the biflavonoids we tested, we found amentoflavone revealed the most potent effects on inhibiting Aβ1-42 fibrillization (IC₅₀: 0.26 µM), as well as on disassembling preformed Aβ1-42 fibrils (EC₅₀: 0.59 µM). Our structure-activity relationship study suggests that the hydroxyl groups of biflavonoid compounds play an essential role in their molecular interaction with the dynamic process of Aβ1-42 fibrillization. Our atomic force microscopic imaging analysis demonstrates that amentoflavone directly disrupts the fibrillar structure of preformed Aβ1-42 fibrils, resulting in conversion of those fibrils to amorphous Aβ1-42 aggregates. These results indicate that amentoflavone affords the most potent anti-amyloidogenic effects on both inhibition of Aβ1-42 fibrillization and disaggregation of preformed mature Aβ1-42 fibrils.

• 복식
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• 제56권4호
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• pp.15-32
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• 2006

The purpose of this study is to research on the actual condition of production and selling in silver apparel market. For the questionnaire, 19 women's wear brands which were in higher ranking of sales in boutiques and madame-zone of department stores were selected. Pattern makers of each brand were questioned about 40 items for this research. The results of the questionnaire were as follows: 1) According to the result of the survey on the made-to-wear production of 19 ready-to-wear manufacturers, there was the gap was in ages between the target and the real consumer. Consumers of these brands were older and aged more broadly than their target ages. 2) Most of the consumers of silver-zone has thick waists, common heights, fat shapes. Custom-made clothes are ordered in many cases because of the big abdomen(50.0%) and H-shape(58.3%) of a somatotype. The body size variation of user population is needed for a good fit. 3) All brands(100%) of this research are using KS standards in the label of clothing, but they don't use these data in their production by reason of unawareness and distrust about these data. These inconsistency between the label and the real size of products may cause a confusion when consumers buy ready-to-wear. 4) Silver apparel manufacturers have need of anthropometry information and dummy(78.6%) suitable for their target consumers to increase their satisfaction about their apparel fit.

• 한국의류산업학회지
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• 제19권5호
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• pp.620-625
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• 2017

In this study, the dyeing conditions(temperature, time, concentration) are changed from various conditions on wool fabrics by using corydalis tuber extract in order to develop new natural dyes. The purpose of this study is to improve the dyeability, color fastness, and functionality and to derive optimal dyeing conditions by comparing and analyzing the changes of K/S values and surface color by dyeing pH changes, mordant method, and mordant type. As a result of the experiment, the optimum dyeing condition of the wool fabrics is shown dyeing temperature:$80^{\circ}C$, dyeing time:90min, dyeing concentration:100%. The dyeability by pH variants of corydalis tuber extract indicates that K/S values is higher alkaline than acidic. The mordant method of corydalis tuber extract showed pre-mordant has high K/S values. In terms of color fastness, marked improvement has not been shown despite of mordant treatment on wool fabrics. In particular, color change of color fastness to washing, color fastness to light indicates the low fastness. In addition, the functionality such as antibacterial activities and deodorization can be given at dyeing with corydalis tuber extract thus it is expected to be applied to underwear or apparel products for the elderly and infirm and children with weak skin that required high functionality.

• 대한의용생체공학회:의공학회지
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• 제36권5호
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• pp.228-234
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• 2015

The balance ability significantly decreased in the elderly because of deterioration of the neural musculature regulatory mechanisms. Several studies have investigated methods of improving balance ability using real-time systems, but it is limited by the expensive test equipment and specialized resources. Recently, Kinect system based on depth data has been applied to address these limitations. Little information about accuracy/inaccuracy of Kinect system is, however, available, particular in motion analysis for evaluation of effectiveness in rehabilitation training. Therefore, the aim of the current study was to evaluate accuracy/inaccuracy of Kinect system in specific rotational movement for balance rehabilitation training. Six healthy male adults with no musculoskeletal disorder were selected to participate in the experiment. Movements of the participants were induced by controlling the base plane of the balance training equipment in directions of AP (anterior-posterior), ML (medial-lateral), right and left diagonal direction. The dynamic motions of the subjects were measured using two Kinect depth sensor systems and a three-dimensional motion capture system with eight infrared cameras for comparative evaluation. The results of the error rate for hip and knee joint alteration of Kinect system comparison with infrared camera based motion capture system occurred smaller values in the ML direction (Hip joint: 10.9~57.3%, Knee joint: 26.0~74.8%). Therefore, the accuracy of Kinect system for measuring balance rehabilitation traning could improve by using adapted algorithm which is based on hip joint movement in medial-lateral direction.

• 한국실내디자인학회논문집
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• 제25권5호
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• pp.111-120
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• 2016

Unlike the past, brick-and-mortar is no longer on the priority list for the shopping activity. Instead, it is replaced by various non-store shopping alternatives, such as Internet, TV, catalog, mobile, etc. As consumers engage digitally, they made fewer trips to stores. Especially, as mobile shopping made the price comparison possible while shopping in the store, new shopping trend of 'showrooming' came to the fore as the serious issue. In order to cope with the this crisis, many brick-and-mortar retailers utilize omni-channel strategy for their countermeasure. This research paper is to suggest the omni-channel strategy that is applicable for the brick-and-mortar retailers. The results are as follows. First, in order to set up the connected-channel shopping environment, consumers have to be exposed to the environment that can deliver the continuous brand experience under the same price policy, brand and store management, etc, as integrating the various purchasing channels into one. Especially, in-store environment needs to change for the place where consumer experience is stressed for the most as using virtual reality devices with augmented reality technology. Also, the online digital kiosk, and tablet that consumer can order the products through the online channel while shopping in-store Second, the barrier-free in-store environment should be offered in order to increase the consumer convenience. This change will allow consumer communicate with the store environment more effectively. Lastly, brick-and-mortar should extend the physical territory as utilizing the offline's advantage and disadvantage through setting up the digital interactive wall or pop-up store for increasing the opportunity of customer interaction with the store. Moreover, visiting service for the elderly, housewife with the baby, or disabled person will be one of the effective substitute.

• 대한인간공학회지
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• 제33권5호
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• pp.313-321
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• 2014

Objective: The purpose of this study is to develop products that prevent muscular skeletal disease of farm workers, which would bring improvement for an efficient harvesting work. Background: A pretest for product development and a survey research was carried out to inspect the problems of current harvesting work procedure. The product was developed and assessed based on ideas to supplement and improve these weak points. Method: A total of twenty men were recruited to evaluate the effects of harvest baskets on the upper-limb muscle activity, working hours. For the usability evaluation, electromyogram and working hours of previous working method (disuse of harvest basket, one-hand carriage of the basket) and new working method with the usage of newly-developed harvest basket was examined. The whole anterior deltoid, biceps brachii and erector spinae on both sides, which make a total of six muscle parts, were used for this experiment. The results were analyzed using ANOVA with muscle activity (%MVC) of each three forms of work and required work time from SPSS 18.0. Results: According to the test result, all muscles did not demonstrate any statistically significant difference, with an exception of the backbone erector (right). The muscle activity of backbone erector (right) in the work method that uses the harvest basket developed in this study was detected to be approximately 23% less than that of the previous working method. Moreover, compared to the previous working method, the required work time decreased to a statistically significant degree. Conclusion: As such, the decrease in the amount of waist muscle usage at harvesting work would enable the prevention of muscular skeletal disease and stabilization of lumbar spine. Application: Which in turn would increase the effectiveness and reduce personnel expense (labor costs) while enhancing productivity with a decreased working hours.

• 재활복지공학회논문지
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• 제9권4호
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• pp.309-317
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• 2015

본 연구에서는 노약자들의 등산활동 시 많이 사용되는 등산스틱의 안전과 성능의 평가를 위한 등산스틱 시험규격 안을 제안하였다. 연관규격조사, 관련 특허 및 논문 조사, 제품현황조사, 파손사례조사, 전문가조사 등을 통해 9가지 등산스틱 성능(안전)요인을 도출하였으며 이 요인들을 시험하기 위한 규격시험장비 3종(비틀림 및 직진도 시험장비, 내구성 시험장비, 스파이크 및 팁 내구성 시험장비)을 설계 제작하였다. 시험에 사용한 시료는 2014년 9월 네이버 쇼핑 기준 판매순위 상위 브랜드 15개의 일자형 손잡이 제품(각 제품별 6개 시료)을 선정하여 사용하였다. 성능요인에 대한 실제시료시험결과 및 전문가회의를 통해 총 6가지의 시험규격 항목 안(편심하중, 길이조절부 압축, 손목걸이 하중, 바스켓 하중, 스파이크 및 팁 내구성, 등산스틱 당김)을 도출하였다.

• Journal of Nutrition and Health
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• 제40권3호
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• pp.249-258
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• 2007

Benign prostatic hyperplasia (BPH) is one the most common prostate diseases in middle aged and elderly men. This study was conducted to investigate diet and lifestyle risk factors for benign prostatic hyperplasia in a community-dwelling free-living population group. The dietary data were collected from the 601 male subjects aged 50-79 years using the 24-hour recall method. The mean age of the BPH group ($63.0{\pm}7.9$ years) was significantly higher than that of the non-BPH ($58.8{\pm}7.4$ years). Among many nutrients, the amount of animal fat intake was increased while that of carbohydrate intake decreased in subjects with BPH compared to those with non-BPH. In BPH subjects, the proportion of energy from fat was also greater than in subjects with non-BPH. The logistic regression analysis on the food consumption data showed that the consumption of total animal food was increased while that of mushrooms was decreased in patients with BPH compared to the subjects with non-BPH. The age-adjusted odds ratios and 95% confidences limits for BPH incidence in subjects whose milk and milk products, beverages and alcoholic liquors intake was greater than the median were 1.796 (1.167-2.782) and 1.738 (1.129-2.676) respectively, compared to those in subjects whose intakes were below the median. These results may be applicable in the development of a nutrition intervention and education program toward a reduction in the risk for benign prostatic hyperplasia.

• KIEAE Journal
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• 제7권1호
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• pp.5-13
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• 2007

Since aging has become one of most hot and serious issues in the whole global world, universal design as a strategic concept to enable the elderly age in place has received much attention and its importance is getting recognized. Japan has undergone the Aging phenomenon much earlier than Korea and other countries. During that time, through much trials and errors, it accumulated the wisdoms and techniques to precede aging friendly environment and products. Therefore current Japan house is a comprehensive setting which embraces lots of universal design features that has a valuable implication for Korean development that faces fast aging future. The purpose of this study was to delineate characteristics of universal design features appeared in Japanese Model houses. One site of housing park in the city where various model houses of representative housing construction companies was selected as a cluster area for data collecting. Data were collected mainly through field survey at the housing park of Tokyo during November, 2006, and additional data were collected through website and company information of relevant company. Universal design features were extracted for 17 houses of the housing park and sorted and analyzed according to the analysis frame. The frame were made using 2 major clusters; space area, and 8 universal design principle. Results showed a range of universal design feature and its detail universal design principle satisfied. The 8 principle currently developed became to house realistic practical examples and theory became proved its impractical power. The academic, educational and industrial implication were documented.