• 제목/요약/키워드: Elderly males

검색결과 344건 처리시간 0.025초

입마름 증상 완화를 위한 기능성 캔디(lozenge) 개발 요구도 조사 (Study on Needs for Functional Candy (lozenges) Development for Oral Dryness)

  • 주경미;정은경;주나미
    • 대한영양사협회학술지
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    • 제26권1호
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    • pp.30-41
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    • 2020
  • As the morbidity of chronic diseases such as diabetes and high blood pressure has increased, the frequency of oral dryness upon taking drugs for a long time or several drugs at the same time has greatly increased. This study was conducted to investigate the status of oral dryness and utilize the data to develop treatment products. Surveys were assembled from October to December 2018, and a statistical analysis of the 144 responses was conducted. The surveyed consisted of 60 males and 84 females, with 31.3% of those in their 70s and older. Among them, 100 people took drugs for chronic diseases, while 27 people took drugs for more than 10 years and less than 20 years. Exactly 23 respondents who took drugs suffered from more than two types of chronic diseases, of which high blood pressure was the most cited, followed by hyperlipidemia and diabetes. Regarding complications, oral dryness (33.8%) was the most frequent, and there were significant differences in the degree of discomfort when taking medicine, especially for oral dryness depending on the age (P<0.05). Groups that took medicine showed severe symptoms of dry mouth, especially when waking up at night or in the morning (P<0.001) and eating food (P<0.01), and had difficulty in swallowing food (P<0.01) and speaking (P<0.01). Exactly 89.6% of the respondents didn't take lozenges (candy) for improvement of oral dryness, and the type of the product that they wanted to purchase the most was candy (45.1%). Respondents worried about rising blood sugar, dental caries, and calories when eating candy for relieving dryness (P<0.01).

Retrospective Review of Effectiveness of Various Pharmacological Agents in Treating Burning Mouth Syndrome

  • Im, Yeong-Gwan;Kim, Byung-Gook;Kim, Jae-Hyung
    • Journal of Oral Medicine and Pain
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    • 제41권1호
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    • pp.21-25
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    • 2016
  • Purpose: Burning mouth syndrome (BMS) is a chronic pain condition involving the oral and perioral regions, often characterized by a burning sensation and pain in elderly patients. In this study, we investigated the effectiveness of pharmacological agents for the treatment of BMS patients through a retrospective chart review. Methods: We enrolled 61 BMS subjects (57 females, 4 males; $66.4{\pm}10.9$ years of age) from among consecutive patients treated pharmacologically from January 2014 to June 2015 at Chonnam National University Dental Hospital. Patients with secondary BMS associated with local factors were excluded. The treatment period, number of pharmacological agents tried, and effectiveness of the drugs administered to each subject were analyzed. Results: The mean treatment period for the management of BMS was 2.5 months. More than three agents were tried to control BMS symptoms in 17 subjects (27.9%); two agents were used in 10 subjects (16.4%), and a single agent in 24 subjects (39.3%). Clonazepam was prescribed most frequently and was effective at relieving symptoms in 30 of 39 subjects (76.9%). Paroxetine was moderately effective, relieving symptoms in 7 of 17 subjects (41.2%). Some of the subjects benefited from tricyclic antidepressants, gabapentin, and lipoic acid. A topical local anesthetic used to supplement other systemic agents had ameliorating effects in four of six subjects. Conclusions: Within the study limitations, clonazepam was the most effective drug and antidepressants were efficacious in some subjects for relieving the symptoms of BMS. These pharmacological agents could be considered as first-line drugs for the management of BMS.

부산지역 백세인의 일상활동 수행능력과 건강관련 삶의 질 (Activities of Daily Living and Health-Related Quality of Life (HRQoL) of Centenarians in Busan)

  • 박형숙;김동희;김윤진;손용진;이정규;임지향
    • 기본간호학회지
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    • 제16권3호
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    • pp.316-324
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    • 2009
  • Purpose: The aim of the study was to identify the relationships among age, activities of daily living and health-related quality of life (HRQoL) for centenarians in Busan. Methods: Forty-nine centenarians (2 males and 47 females) participated in the study, done from April to July, 2006. Pace-to-face interviews were used to collect data. Activities of daily living were measured using K-ADL, K-IADL and health-related quality of life, using the Short Form Health Survey (SF-36). Results: Over 50% of the centenarians reported independence for six-items but not for bathing. With regard to type of dependency, 77.6% were independent in transferring, 71.4%, in using the toilet, 67.3%, in feeding and in continence and 57.1% in dressing but just 24.5% were independent in bathing. Age was significantly associated with K-IADL (r= -.303, p= .03). The centenarians were more impaired in physical health components compared to mental health components for health-related quality of life. Conclusion: These results may contribute to a better understanding of activities of daily living and health-related quality of life of centenarians. The findings are relevant to health professionals, in particular professionals who are developing wellness programs to optimize health-related quality of life and functional status for the extremely old age population.

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Prevalence and Risk Factors for Lumbar Spondylosis and Its Association with Low Back Pain among Rural Korean Residents

  • Lee, Sung Yeon;Cho, Nam H.;Jung, Young Ok;Seo, Young Il;Kim, Hyun Ah
    • Journal of Korean Neurosurgical Society
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    • 제60권1호
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    • pp.67-74
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    • 2017
  • Objective : The purpose of this study was to investigate the prevalence of and the relevant risk factors for lumbar spondylosis (LS) among middle-aged and elderly rural Korean residents and to explore the association between radiographic LS and lower back pain (LBP) in relation to age and gender. Methods : This community-based, cross-sectional study evaluated 1512 subjects with available radiograph. The prevalence of LBP was obtained using a questionnaire and disability resulting from LBP was measured using a validated Korean version of the Oswestry disability index (ODI). In lumbar spine radiographs, vertebral levels from L1/2 to L4/5 were evaluated for the presence of osteophytes and joint-space narrowing (JSN), and Kellgren-Lawrence (KL) grading was applied. Results : Of 4261 subjects aged 40-79 years, data from 1512 subjects were included. The prevalence of radiographic LS indicated by grade ${\geq}2$ osteophytes and JSN were 53.9 and 15.8%, respectively. Seventy-three percent of subjects had KL grade ${\geq}2$ spondylosis and LBP was present in 36.5% of subjects. Although LS was more common among males, the prevalence of LBP was higher among females. Age, male gender and history of hand or knee arthritis were risk factors for LS. LS was significantly associated with LBP mostly among females over 60 years old and correlated with the ODI after adjusting for age and gender. Conclusion : Our study among rural Korean residents revealed a high prevalence of LS and LBP. The association between LS and LBP was observed mostly among females and LS was significantly correlated with the severity of back pain.

Estimation of the National Burden of Disease and Vulnerable Population Associated with Natural Disasters in Korea: Heavy Precipitation and Typhoon

  • Han, Hyun-Jin;Kim, Jong-Hun;Chung, Soo-Eun;Park, Jae-Hyun;Cheong, Hae-Kwan
    • Journal of Korean Medical Science
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    • 제33권49호
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    • pp.314.1-314.15
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    • 2018
  • Background: Despite its growing significance, studies on the burden of disease associated with natural disasters from the perspective of public health were few. This study aimed at estimating the national burden of disease associated with typhoons and torrential rains in Korea. Methods: During the period of 2002-2012, 11 typhoons and five torrential rains were selected. Mortality and morbidities were defined as accentual death, injury and injury-related infection, and mental health. Their incidences were estimated from National Health Insurance Service. Case-crossover design was used to define the disaster-related excess mortality and morbidity. Disability-adjusted life years (DALYs) were directly assessed from excess mortality and morbidity. Results: The burden of disease from typhoons increased with the intensity, with 107.7, 30.6, and 36.6 DALYs per 100,000 per event for strong, moderate, and weak typhoons, respectively. Burden of disease from torrential rains were 56.9, 52.8, and 26.4 DALYs per 100,000 per event for strong, moderate, and weak episodes, respectively. Mental disorders contributed more years lived with disability (YLDs) than did injuries in most cases, but the injury-induced YLDs associated with strong typhoon and torrential rain were higher than those of lower-intensity. The elderly was the most vulnerable to most types of disaster and storm intensities, and males younger than 65 years were more vulnerable to a strong torrential rain event. Conclusion: The intensity of torrential rain or typhoon was the strongest determinant of the burden of disease from natural disasters in Korea. Population vulnerable may vary depending on the nature and strength of the disasters.

6-sialyllactose ameliorates dihydrotestosterone-induced benign prostatic hyperplasia through suppressing VEGF-mediated angiogenesis

  • Kim, Eun-Yeong;Jin, Bo-Ram;Chung, Tae-Wook;Bae, Sung-Jin;Park, Hyerin;Ryu, Dongryeol;Jin, Ling;An, Hyo-Jin;Ha, Ki-Tae
    • BMB Reports
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    • 제52권9호
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    • pp.560-565
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    • 2019
  • Benign prostatic hyperplasia (BPH), a common disease in elderly males, is accompanied by non-malignant growth of prostate tissues, subsequently causing hypoxia and angiogenesis. Although VEGF-related angiogenesis is one of the therapeutic targets of prostate cancer, there is no previous study targeting angiogenesis for treatment of BPH. Dihydrotestosterone (DHT)-induced expressions of vascular endothelial growth factor (VEGF) in prostate epithelial RWPE-1 cells and human umbilical vascular endothelial cells (HUVECs). Conditioned media (CM) from DHT-treated RWPE-1 cells were transferred to HUVECs. Then, 6SL inhibited proliferation, VEGFR-2 activation, and tube formation of HUVECs transferred with CM from DHT-treated RWPE-1 cells. In the rat BPH model, 6SL reduced prostate weight, size, and thickness of the prostate tissue. Formation of vessels in prostatic tissues were also reduced with 6SL treatment. We found that 6SL has an ameliorative effect on in vitro and in vivo the BPH model via inhibition of VEGFR-2 activation and subsequent angiogenesis. These results suggest that 6SL might be a candidate for development of novel BPH drugs.

Correlation between Telomere Length and Chronic Obstructive Pulmonary Disease-Related Phenotypes: Results from the Chronic Obstructive Pulmonary Disease in Dusty Areas (CODA) Cohort

  • Moon, Da Hye;Kim, Jeeyoung;Lim, Myoung Nam;Bak, So Hyen;Kim, Woo Jin
    • Tuberculosis and Respiratory Diseases
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    • 제84권3호
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    • pp.188-199
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    • 2021
  • Background: Chronic obstructive pulmonary disease (COPD) is a common chronic respiratory disease with increased prevalence in the elderly. Telomeres are repetitive DNA sequences found at the end of the chromosome, which progressively shorten as cells divide. Telomere length is known to be a molecular marker of aging. This study aimed to assess the relationship between telomere length and the risk of COPD, lung function, respiratory symptoms, and emphysema index in Chronic Obstructive Pulmonary Disease in Dusty Areas (CODA) cohort. Methods: We extracted DNA from the peripheral blood samples of 446 participants, including 285 COPD patients and 161 control participants. We measured absolute telomere length using quantitative real-time polymerase chain reaction. All participants underwent spirometry and quantitative computed tomography scan. Questionnaires assessing respiratory symptoms and the COPD Assessment Test was filled by all the participants. Results: The mean age of participants at the baseline visit was 72.5±7.1 years. Males accounted for 72% (321 participants) of the all participants. The mean telomere length was lower in the COPD group compared to the non-COPD group (COPD, 16.81±13.90 kb; non-COPD, 21.97±14.43 kb). In COPD patients, 112 (75.7%) were distributed as tertile 1 (shortest), 91 (61.1%) as tertile 2 and 82 (55%) as tertile 3 (longest). We did not find significant associations between telomere length and lung function, exacerbation, airway wall thickness, and emphysema index after adjusting for sex, age, and smoking status. Conclusion: In this study, the relationship between various COPD phenotypes and telomere length was analyzed, but no significant statistical associations were shown.

경남 일부지역 장수노인의 영양섭취상태에 관한 연구 (A Study on Nutritional Status of the Long-lived Elderly People in Kyungnam)

  • 최희정;김경업;김성희;강동희;정효숙
    • 한국식품영양과학회지
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    • 제31권5호
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    • pp.877-884
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    • 2002
  • 본 연구는 경남 남해 장수노인들의 영양섭취 상태 및 식품 선호도를 조사 평가함으로써 건강한 장수를 위한 식생활의 기초자료를 얻고자 수행되었는데 그 결과를 요약하면 다음과 같다. 1. 조사 대상자는 남자가 24명, 여자가 76명으로 평균 연령은 남자 88.7$\pm$3.6세, 여자 89.2$\pm$4.2세였다. 남녀 각각 평균 신장은 160.2$\pm$7.1 cm, 147.0$\pm$5.6 cm, 평균 체중은 52.6$\pm$8.4 kg, 44.9$\pm$7.1 k9이었으며 노인 평균 BMI 및 WHR은 208$\pm$3.1, 0.88$\pm$0.1이었고 수축기와 확장기 혈압은 149.9+30.1 mmHg, 87.2$\pm$14.8 mmHg였다 2. 평균 1일 열량 섭취량은 1547$\pm$432.7 kcal로 75세 이상 한국인영양권장량의 91.3%를 차지하였다. 단백질(63.1$\pm$28.2 g), 철분(16.7$\pm$11.2 mg), 비타민 B$_1$(1.04$\pm$0.4 mg) 및 비타민 C(97.0$\pm$45.3 mg)의 섭취는 권장량 이상을 섭취하였고 칼슘(418.1$\pm$189.7 mg) 및 비타민 B$_2$(0.94$\pm$0.5 mg)의 섭취는 각각 권장량의 58%,78%정도로 가장 부족한 실정이었다. 또한 열량 및 대부분의 영양소 섭취량은 여자가 남자보다 많았다. .:. 열량, 단백질 및 지질의 식품군별 섭취 비율을 살펴본 결과 열량 및 단백질의 급원으로 곡류 및 전분류의 의존도가 매우 컸으며 그 다음 순이 육류, 생선, 달걀 및 콩류였는데 이 중 생선류에 대한 의존도가 가장 컸고 육류의 의존도는 현저히 낮았다. 지질은 육류, 생선, 달걀 및 콩류로부터 의 섭취비율이 가장 높았는데 이 중 콩류가 차지하는 비율이 가장 높았다. 4. 식품군별 식품의 선호도에 있어서 곡류 및 전분류에서는 밥을 우리나라 주식 인 만큼 가장 선호하였고 과일 및 채소류에서는 거의 모든 종류의 채소류를 가장 좋아하며 그 다음으로 남자는 해조류를, 여자는 김치를 좋아하였다. 육류, 생선, 달걀 및 콩류에서는 생선류의 선호도는 가장 높은 반면 육류의 선호도는 가장 낮았다 우유 및 유제품류에서는 약 90%의 노인이 요구르트를 선호하였고 유지 및 당류에서는 당류를 가장 선호하였다. 그리고 식품의 맛에 대한 선호도에서는 대부분이 단맛을 좋아하였으며 신맛은 아무도 좋아하지 않았다. 본 연구 결과에서 경남 남해의 장수노인들은 대부분의 영양소 섭취상태가 양호하였고 열량 및 단백질 섭취는 곡류 및 전분류로부터의 의존도가 가장 컸으며 동물성 식품 중에서는 생선 및 어 패류를 가장 선호함과 아울러 그 섭취량이 제일 많은 것으로 나타났다.

영남 일부지역 65세 이상 노인의 섭취상태와 영양지식에 관한 연구 (Nutritional Status and Knowledge of the Elderly over 65 Years in Young-Nam Area)

  • 김성미
    • 동아시아식생활학회지
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    • 제13권2호
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    • pp.98-110
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    • 2003
  • 65세 이상 노인 204명(남자 94명, 여자 110명))을 대상으로 영양소섭취상태와 영양지식점수를 분석한 결과는 다음과 같다. 1) 연령분포는 65~74세 99명(48.5%), 75세 이상 105명(51.5%)이었으며, 가정 총 수입은 99만원 이하 47명(23%), 100만원에서 199만원 115명(56.4%), 200만원이상 42명(20.6%)으로 나타났다. 가족 형태는 핵가족 97명(47.5%), 확대가족 107명(52.5%)이었다. 2)권장량에 비해서 높게 섭취하는 에너지 및 영양소는 단백질, 비타민 C, 비타민 $B_1$.나이아신 및 인 등이었으며 에너지 섭취량이 남자보다 여자가 많았다. 비타민 $B_2$의 경우, 남녀 모두 가장 낮은 섭취상태를 보였고, 칼슘 역시 낮은 섭취상태를 나타내었다. 3) 영양소 적정섭취비(NAR)는 비타민 $B_2$,가 가장 낮아 0.66이었고, 칼슘 역시 0.68로 낮은 값을 보였으며, 가장 높dms 영양소 적정섭취비는 인으로서 남녀전체 0.99, 남자 1.0을 나타내었다. 평균적정섭취비(MAR)는 65~74세 집단에서 남자가 여자보다 높아 남자노인의 식사의 질이 여자노인의 식사의 질보다 높았다. 모든 대상자의 영양의 질적지수(INQ)는 비타민 $B_2$,(0.71)와 칼슘(0.76)을 제외하고 모든 영양소의 값이 1을 넘어섰다. 4) 영양지식점수를 상, 중, 하의 3 집단으로 분류하여 영양소 섭취량(%RDA)을 비교할 때 상 점수 집단이 하 점수집단보다 에너지, 단백질, 비타민 A, 비타민 $B_1$, 비타민 $B_2$.나이아신 및 철의 섭취량이 높게 나타났다. 그러나 영양지식점수 상 집단에서는 단백질, 비타민 C, 비타민 Bl 등의 섭취량이 권장량에 비하여 매우 높았고, 부족 되는 영양소인 비타민 B2와 칼슘은 권장량에 비하여 매우 낮았다. 5) 영양지식점수는 연령과는 매우 유의 적인 음(r=-0.398)의 상관관계가, MAR(r=0.152), 단백질(r=0.151) 등은 유의 적인 양의 상관관계가 있었다. 이상의 결과에서 가장 부족하게 섭취하는 영양소는 비타민 $B_2$와 칼슘으로 나타났다. 반면 인의 섭취량은 권장량을 상회하는 높은 섭취량을 보였으며, 따라서 인과 칼슘의 비가 2를 넘어섰다. 이는 노인의 골격상태에 나쁜 요인으로 작용 할까 우려된다. 또한 영양지식점수가 높은 집단에서도 비타민 $B_2$와 칼슘이 권장량에 비해서 매우 낮은 섭취상태를 보였고, 또한 권장량에 비해서 지나치게 초과 섭취하는 영양소 등이 있음은 올바른 영양소 섭취가 이루어지지 않았음을 나타내었다. 이론적 지식이 실천적 지식으로 활동될 수 있는, 개개인 노인에게 적합한 영양교육이 이루어질 수 있는 방안이 연구되어야 한다고 생각한다.

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경북지역 장수노인의 저작능력과 건강상태 (The Relationship Between Chewing Ability and Health Status in the Long-lived Elderly of Kyungpook Area)

  • 이희경;이영권
    • Journal of Yeungnam Medical Science
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    • 제16권2호
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    • pp.200-207
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    • 1999
  • 본 연구는 구강보건측면에서의 장수를 위한 노인생활지침을 설정하기 위한 기초자료를 제공하기 위해 85세 이상 노인들의 구강검진을 통하여 구강내 실태조사와 저작능력의 상태를 파악하고 구강상태에 따른 건강상태 및 신체계측치를 비교함으로 다음과 같은 결과를 얻었다. 1. 전체 97명 중 남자가 27.8%, 여자가 72.2%이었고, 평균연령은 $88.14{\pm}3.20$세 이었다. 조사대상자의 노인들이 53.6%가 건강하다고 하였다. 조사 대상자의 평균키는 $148.8{\pm}11.2cm$, 평균몸무게는 $46.9{\pm}10.5kg$, 평균BMI는 $21.2{\pm}3.5kg/m^2$, 평균체지방율은 $26.7{\pm}6.9%$, 평균제지방율은 $73.0{\pm}7.1%$, 평균체수분율은 $53.4{\pm}5.2%$로 나타났다. 2. 잔존치아수는 $3.50{\pm}5.71$개로 상악이 $1.08{\pm}2.88$개, 하악이 $2.41{\pm}3.76$개로 나타났고 최대 잔존치아 수는 22개이었고, 치아가 없는 노인이 전체의 76.3%나 되었다. 저작양상은 상,하 의치를 사용하는 노인이 전체의 52.6%, 자기치아만으로 저작(자연치 교합)하는 노인이 23.7%, 치아도 없으며 의치도 사용하지 않는 노인이 23.7%로 나타났다. 3. 저작양상에 따른 주관적 건강상태와 소화상태, 저작능력을 보면 의치 교합군에서 47.1%, 치아도 없이 의치도 사용 안하는 군에서는 56.5%, 자연치교합군에서는 65.2%가 건강하다고 했고, 소화상태도 의치군이 82.4%, 치아도 없이 의치도 사용 안하는 군이 65.2%, 자연치 교합군이 73.9%로 좋다고 했고, 저작능력도 의치군이 90.2%, 치아도 없이 의치도 사용 안하는 군이 60.9%, 자연치 교합군이 65.2%로 좋다고 하였다. 4. 저작영상에 따른 키, 몸무게, 체지방율, 제지방율, 총수분량을 비교하면 의치교협군에서 $150.0{\pm}10.7cm$, $49.0{\pm}10.9kg$, $26.9{\pm}6.6%$, $72.7{\pm}7.0%$, $53.2{\pm}5.1%$이며 치아도 없이 의치도 사용 안하는 군에서는 $142.7{\pm}6.0cm$, $43.2{\pm}5.5kg$, $29.5{\pm}7.2%$, $70.8{\pm}6.9%$, $51.8{\pm}5.0%$이고 자연치교합군에서는 $152.3{\pm}14.1cm$, $45.9{\pm}12.6kg$, $23.4{\pm}6.0%$, $75.9{\pm}6.9%$, $55.6{\pm}5.1%$로 나타났다. 저작양상 대한 신체계측치는 키, 체지방율, 제지방율, 총수분율에서 의치를 사용하는 군, 자연치교합군, 치아도 없이 의치도 사용 안하는 군의 순으로 유의하게 양호한 것으로 나타났다.

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