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Anti-inflammatory effects of Chamaecyparis obtusa (Siebold & Zucc.) Endl. Leaf Fractions (편백(Chamaecyparis obtusa (Siebold & Zucc.) Endl.) 잎 분획물의 항염증 효과)

  • Yong-Jin Kwon
    • Journal of the Korean Applied Science and Technology
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    • v.40 no.6
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    • pp.1268-1277
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    • 2023
  • In this study, to evaluate the possibility of utilizing Chamaecyparis obtusa (Siebold & Zucc.) Endl. (C. obtusa) leaf fractions as anti-inflammatory functional materials, C. obtusa extract extracted with 99% ethanol (CO99EL) was fractionated with hexane (CO99EL-H), chloroform (CO99EL-C), ethyl acetate (CO99EL-E), butanol (CO99EL-B) and distilled water (CO99EL-W). The anti-inflammatory effects of each fraction was performed using lipopolysaccharide (LPS)-induced RAW264.7 mouse macrophages. Cytotoxicity was highest in CO99EL-H and CO99EL-C and lowest in CO99EL-W. Interestingly, LPS-induced iNOS expression and NO production were significantly reduced by CO99EL-H and CO99EL-E, and COX-2 expression was significantly reduced by CO99EL-B and CO99EL-W. In addition, interleukin (IL)-1𝛽, an inflammatory cytokine increased by LPS, was significantly reduced by CO99EL-C, CO99EL-E, CO99EL-B and CO99EL-W, and IL-6 was significantly reduced by CO99EL-B and CO99EL-W. Therefore, the janus kinase (JAK)/signaling transducer and activator of transcription (STAT) signaling pathway activated by LPS was significantly reduced by CO99EL-H and CO99EL-C, and the mitogen-activated protein kinase (MAPK) signaling pathway was slightly reduced by CO99EL-H and CO99EL-C. However, nuclear factor (NF)-𝜅B activity was not reduced by any fractions. Based on the results of this study, it was confirmed that CO99EL fractions have different anti-inflammatory mechanisms depending on the solvent used for fractionation.

Enfrentamiento con el trauma a través de análisis de personajes femeninos en (영화, <루시아>의 여성 인물 분석을 통한 트라우마 직면의 문제)

  • Park, Chong-Wook
    • Iberoamérica
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    • v.12 no.1
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    • pp.187-212
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    • 2010
  • El cine como medio de narrar el trauma histórico de los cubanos se formó especialmente en los años sesenta gracias al Instituto Cubano del Arte e Industria Cinematográficos y se sitúa en la cumbre. En el cine hecho por el director cubano Humberto Solás el discurso de historia, trauma y su memoria tiende a relatar básicamente sobre el mensaje de no olvidar el trauma histórico a través de buscar la manera eficaz e intrínseca de narrarlo. El hecho de no olvidar el trauma histórico y de poder enfrentarse con los elementos causantes del trauma significa el poder de tener la posibilidad probable de adquirir la mirada objetiva para observar la experiencia 'histórica' y la memoria 'cotidiana', y sus relaciones. Si consideramos el hecho de que la tendencia de la víctima suele querer olvidar la memoria del trauma por el miedo y dolor de enfrentarse con la representación del trauma, el enfrentarse con el trauma representado ya puede significar que la víctima esté en un trámite de conseguir la penetración con la cual supera lo negativo que le ofrece el trauma a la víctima. Este artículo se dedica especialmente para averiguar la estrategia del director cubano para realizar este fin de encontrar la manera adecuada en narrar el trauma cubano para que los cubanos puedan adquirir la penetración a través de la identificación y la simpatía entre los personajes del cine y los espectadores, enfocando con detalle en los carácteres de los protagonistas femeninas que son tres diferentes individuos en el mismo número de episodios. Cada protagonista, Lucía en cada episodio experimenta el trauma personal con diversos motivos, pero a pesar del dolor y del miedo del trauma histórico se despiertan los espectadores, quienes se identifican con la protagonista a través de la simpatía y la identificación, llegándose al momento de conseguir la penetración con la cual mira el futuro de la sociedad cubana con el objetivismo libre de los traumas históricos.

Inverter Design and Control for Driving Electro-Luminescence Sheet (EL 시트 구동을 위한 인버터의 설계 및 제어)

  • Lee, Seung-Yo
    • The Transactions of the Korean Institute of Power Electronics
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    • v.14 no.5
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    • pp.355-364
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    • 2009
  • Electro-Luminescence (EL) sheets have been widely used in lighting displays, mainly used as advertisement panels. To drive the ELs in optimal conditions, it is required to understand the load profile of the EL. Hence, in this paper, a modeling for an EL sheet was performed to analyze the load characteristics of the EL. Based on the extracted model of the EL, a topology for inverter system was chosen and the optimal design parameters were obtained. The validity of the designed EL driver system was verified through computer simulations and experiments.

Formas Pronominales de Tratamiento en la Enseñanza del Español como Lengua Extranjera (스페인어 교육과 대명사 호칭어)

  • Kim, Uh-Sung
    • Iberoamérica
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    • v.11 no.2
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    • pp.65-89
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    • 2009
  • El presente trabajo tiene como objetivo proporcionar una explicación simplificada pero suficiente sobre el uso de las formas pronominales de tratamiento en los países de habla española, y hacer una propuesta para la enseñanza de los pronombres de tratamiento en la enseñanza del español en Corea. En la actualidad, en el mundo hispánico existen varios sistemas de tratamiento pronominal. La distribución dialectal de sus formas es bastante complicada. En la norma de España se usa el tú para el trato informal en oposición con el usted para el trato formal. Mientras tanto, en Hispanoamérica se usan el tú y el vos para el trato informal, y el usted para el trato formal. Sin embargo, la mayoría de las gramáticas didácticas y manuales no ofrece una explicación suficiente en cuanto a las diferencias de las formas y el uso de los pronombres de tratamiento. En Corea, en la mayoría de las clases de español se enseñan sólo la norma de España, que es minoitaria entre la comunidad global de hispanohablantes. Eso no les permitiría a los estudiantes tener una interacción exitosa con personas que dominen otras normas del tratamiento pronominal. Para que los alumnos tengan una competencia comunicativa que sea lo más universalmente válida, es necesario ofrecer una perspectiva de los fenómenos lingüísticos y culturales que toman en cuenta las variedades del sistema del tratamiento pronominal que se usan hoy en día en el dominio hispánico. Por último, los intereses y el nivel de los alumnos son variables que determinan qué o cuánto hacer en la enseñanza de las formas pronominales de tratamiento.

Study of the Relationship between the East Asian Marginal SST and the Two Different Types of El Niño (서로 다른 두 유형의 엘니뇨와 동아시아 인근 해역 표층 온도 상관성 연구)

  • Yoon, Jin-Hee;Yeh, Sang-Wook
    • Ocean and Polar Research
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    • v.31 no.1
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    • pp.51-61
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    • 2009
  • In this study we define the two different types of El $Ni{\tilde{n}}o$, i.e., the eastern Pacific El $Ni{\tilde{n}}o$ (i.e., EP-El $Ni{\tilde{n}}o$) versus the central Pacific El $Ni{\tilde{n}}o$ (i.e., CP-El $Ni{\tilde{n}}o$), during the boreal summer (June-July-August, JJA) and winter (December-January-February, DJF) using the two NINO indices in the tropical Pacific. The two different types of El $Ni{\tilde{n}}o$ significantly differ in terms of the location of the maximum anomalous sea surface temperature (SST) in the tropical Pacific. The CP-El $Ni{\tilde{n}}o$ has been observed more frequently during recent decades compared to the EP-El $Ni{\tilde{n}}o$. In addition, our analysis indicates that the statistics of CP-El $Ni{\tilde{n}}o$ during JJA is closely associated with the warming trend in the central equatorial Pacific. We also examine the different responses of the East Asian marginal SST to the two types of El $Ni{\tilde{n}}o$ during JJA and DJF. The CP-El $Ni{\tilde{n}}o$ during both JJA and DJF is concurrent with warm SST anomalies around the Korean Peninsula including the East China Sea, which is in contrast to the EP-El $Ni{\tilde{n}}o$. Such different responses are associated with the difference in tropics/mid-latitude teleconnections via atmosphere between the two types of El $Ni{\tilde{n}}o$. Furthermore, our results indicate that atmospheric diabatic forcing in relation to the precipitation variability is different in the tropical Pacific between the EP-El $Ni{\tilde{n}}o$ and the CP-El $Ni{\tilde{n}}o$.

Un Estudio sobre la Organización Nacional de República Argentina Moderna : Enfocando en el Conflicto entre los Federales y los Unitarios (독립 후 아르헨티나공화국의 수립과정 연구 : 연방파와 통합파의 갈등을 중심으로)

  • Cho, Young-Shil
    • Iberoamérica
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    • v.13 no.1
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    • pp.287-317
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    • 2011
  • En este trabajo tratamos de investigar el proceso la constitución nacional de la República Argentina moderna, enfocando en la contradicción entre los federales y los unitarios. En el capítulo II, ante todo hemos definido el origen y el contexto de formación de cada ideología y partido. El centro de los federales estaba en las provincias interiores y litorales, mientras que los unitarios hacen de centro la provincia de Buenos Aires. En el capítulo III, mostramos las causas de esta contradicción histórica y tratamos de caracterizar las diferencias. Explícitamente el conflicto se basa en la distinción de la visión política e ideológica, es decir, la distinción de cómo orientar la constitución nacional de la república incipiente. Sin embargo, es inevitable referir la división administrativa histórica durante la época colonial. Al mismo tiempo no debemos faltar el conflicto de interés económico respecto al puerto de Buenos Aires. En el capítulo IV, analizamos comparando las ideas de dos intelectuales, las cuales hacen un papel importante en la organización nacional. Primero analizamos el pensamiento civilizatorio de Sarmiento, y después, demostramos el pensamiento federalista de Alberdi como origen de la constitución argentina de 1853, y de la inmigración europea. Como consecuencia del estudio, podemos llegar a la conclusión de que los esfuerzos por realizar la organización nacional no siempre estaban en línea paralela de ambos partidos divididos, sino tenemos un ejemplo dialéctico y combinatorio como el caso de Alberdi.

Isolation and Characteristics of Endolichenic Fungi Producing Antifungal Compound (항진균성 물질을 생산하는 지의류 내생 곰팡이의 선별 및 특성)

  • Hwang, Hyun-Gook;Kim, Yi-Na;Baik, Keun-Sik;Choi, Sang-Ki
    • Korean Journal of Microbiology
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    • v.47 no.1
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    • pp.97-101
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    • 2011
  • To isolate a novel antifungal compound, we obtained 107 kinds of endolichenic fungi from Lichen Bioresources Center and examined their antifungal capability. Two fungi EL123 and EL156 showed high antifungal activity against Candida albicans in both MYA and EMM media. Nucleotide sequence analysis and NCBI Blast analysis in ITS region including 5.8S rRNA revealed that EL123 has 95% homology with Thielavia microspora and EL156, 99% with Cryptosporiopsis diversispora which belong to Ascomycetes. It observed that EL156 formed a branched mycelium whereas EL123 formed a straight one. EL156 also produced the antifungal substance faster than EL123 when they grew on MY liquid medium.

Studies on Utilization of Diaminododecane by Microbacterium sp. EL-0112 L (Microbacterium sp. EL - 0112L의 Diaminododecane 자화에 관한 연구)

  • 이미연;이상준
    • Journal of Environmental Health Sciences
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    • v.11 no.2
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    • pp.65-75
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    • 1985
  • Microorganisms capable of utilizing diaminododecane containing amine groups diterminally were isolated from the soil by enrichment culture. One strain of these isolated strain, designated as EL-0112L, was selected for this study. The results of this study were as follows. 1. This isolated strain EL-0112L was identified as Microbacterium, from the results of morphological, cultural, and biochemical tests. This isolated strain was named temporarily Microbacterium sp. EL-0112L for convenience. 2. Microbacterium sp. EL-0112L was tested for ability to utilize different kinds of substitued alkanes containing cyan, amine, chloro, and thiol groups(monoterminally or diterminall substituted) as carbon source. Pentamethylenediamine, hexamethylenediamine, n-decane, laurylamine, and alkane derivatives containing cyan, chloro, and thiol groups were not utilized by Microbacterium sp. EL-0112L. 3. The alkane derivatives that did not serve as growth substrates were tested further in oxidation tests using resting cell preparation of Microbacterium sp. EL-0112 L. Alkane derivatives containing cyan, chloro, thiol groups, and n-decane were oxidized by Microbacterium sp. EL-0112 L. It is possible that this isolated strain is also able to degrade their substituted counterparts since they are structually similar to diaminododecane. The remarkable substrates that were being oxidized were dichlorodecane, and 1-dodecanethiol. Microbacterium sp. EL- 0112L could not oxidize pentamethylenediamine, and hexamethylenediamine. 4. The metabolic products formed from diaminododecane by Microbacterium sp. EL-0112 L were acid compound containing carboxyl group and not containing amine group. On the thin layer chromatography, Rf values of these metabolic products were different from that of the product formed by Corynebacterium sp. EL-0112L. These results suggested the specificity of diaminododecane as carbon source.

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The Effectiveness of a New Systemic Fungicide EL-291 for the Control of Rice Blast Disease (새로운 침투성살균제 EL291의 벼 도열병 방제효과)

  • Hwang Byung Kook;Lee Eun Jong;Park Chang Seuk;Lee Kyung Hee
    • Korean journal of applied entomology
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    • v.15 no.2 s.27
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    • pp.57-60
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    • 1976
  • Experiments were carried out to determine the effectiveness of a new systemic fungicide EL-291 (5-Methyl-1, 2,4-triazolo (3,4-b) benzothiazole) for the control of rice blast disease in greenhouse and paddy field. The efficiency of EL-291 was much greater when applied before inoculation than when applied after inoculation. Kasugamin and Benlate were most effective as eradicants. For control of leaf blast, effectiveness of EL-291 was not significantly different than either Kasugamin or Benlate. However, EL-291 was considered more economical and reliable than either Kasugamin or Benlate. EL-291 required only a single foliar application or a transplant root soak, whereas two applications of the other fungicides were required. EL-191 was also more effective against panicle blast when applied only once, compared with two applications of Kasugamin or Benlate. The highest riceyields were obtained in plots treated with EL-29l.

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Hydrological variability in the Han River basin during different phases of El Ni$\tilde{n}$o (서로 다른 엘니뇨 형태에 따른 한강유역의 수문학적 변동성 분석)

  • Kim, Jong-Suk;Yoon, Sun-Kwon;Lee, Joo-Heon;Moon, Young-Il
    • Proceedings of the Korea Water Resources Association Conference
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    • 2012.05a
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    • pp.197-197
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    • 2012
  • 본 연구에서는 대기 순환패턴 및 수문 환경변화에 영향을 미치는 주요인자인 El Ni$\tilde{n}$o-Southern Oscillation (ENSO)의 서로 다른 형태인 Warm-pool (WP) El Ni$\tilde{n}$o, Cold-tongue (CT) El Ni$\tilde{n}$o에 따른 한강유역의 봄철 (March~May)과 여름철 (June~August) 강수 및 유출의 특성을 분석하였다. 봄철 강수량의 경우, WP El Ni$\tilde{n}$o 시기에 증가추세를 보이며, 강수의 변동특성 또한 크게 나타났다. 여름철 강수량의 경우, CT El Ni$\tilde{n}$o 시기에는 평년보다 대체로 건조한 경향을 보이나, WP El Ni$\tilde{n}$o 시기에는 유역 전체에서 습한 경향을 보였으며 강수의 변동성은 매우 작은 것으로 분석되었다. 봄철 유출량의 경우, CT El Ni$\tilde{n}$o 시기와 WP El Ni$\tilde{n}$o 시기에 모두 평년치보다 크게 나타났으며, WP El Ni$\tilde{n}$o 시기에 한강 남부 대부분 유역에서 유출량이 통계적으로 유의한 증가 경향을 보였다. 여름철 유출량의 경우, CT El Ni$\tilde{n}$o 시기에는 대부분 유역에서 평년치보다 감소하나 수문 변량의 변동성은 큰 것으로 분석되었다. WP El Ni$\tilde{n}$o 시기에는 거의 모든 유역에서 유출이 증가하는 것으로 나타났으며, 특히 13개 중권역에서는 유출의 변동성이 작고 통계적으로 유의한 증가패턴이 분석되었다. 따라서 본 연구는 서로 다른 두가지 형태의 El Ni$\tilde{n}$o패턴에 대하여 한강유역의 봄철과 여름철 수자원 변동성에 민감하게 영향을 미치고 있음을 확인하였으며 수자원의 효율적인 예측 및 관리와 안정적인 용수공급을 위한 수문기상인자와 수문자료간의 관계 규명에 유용하게 활용될 것으로 기대한다.

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