• Journal of the Korean Recycled Construction Resources Institute
• /
• v.11 no.4
• /
• pp.484-492
• /
• 2023

The structural behaviour of concrete beam was examined by the three points bending test after the completion of the electrochemical chloride extraction (ECE), rather than bond strength mostly measured in previous studies. It was found that the flexural rigidity of concrete was lowered by the ECE, but the strength was enhanced in terms of the maximum load.The flexural rigidity, in the linear elastic range, was reduced by the loss of effective cross-section area. In fact, the inertia moment was substantially subjected to 70 % loss of the cross-section by the tensile strain at the condition of the failure. However, a lower rate of the inertia moment reduction was achieved by the ECE, implying the higher resistance to the cracking, but the higher risk of deformation.

• Transactions of Materials Processing
• /
• v.32 no.6
• /
• pp.311-320
• /
• 2023

Recently, lightweight of automotive parts has been required to solve environmental problems caused by global warming. Accordingly, research and development are proceeded on manufacturing of parts using aluminum that can replace steel for lightweight of the automotive parts. In addition, high strength aluminum can be applied to body parts in order to meet both requirements of lightening and improving crash safety of vehicle. In this study, hot blow forming of roof side rail is employed to manufacturing of the automotive parts with high strength aluminum tube. In hot blow forming, longer forming times and excessive thinning can be occurred as compared with conventional manufacturing processes. So optimization of process conditions is required to prevent excessive thinning and to uniformize thickness distribution with fast forming time. Mechanical properties of high strength aluminum are obtained from tensile test at high temperature. These properties are used for finite element(FE) analysis to investigate the effect of strain rate on thinning and thickness distribution. Variation of thickness was firstly investigated from the result of FE analysis according to tube diameter, where the shapes at cross section of roof side rail are compared with allowable dimensional tolerance. Effective tube diameter is determined when fracture and wrinkle are not occurred during hot blow forming. Also FE analysis with various pressure-time profiles is performed to investigate the their effects on thinning and thickness distribution which is quantitatively verified with thinning factor. As a results, optimal process conditions can be determined for the manufacturing of roof side rail using high strength aluminum.

• Parasites, Hosts and Diseases
• /
• v.61 no.4
• /
• pp.439-448
• /
• 2023

Tick infestation causes a significant threat to human and animal health, requiring effective immunological control methods. This study aimed to investigate the potential of recombinant Haemaphysalis longicornis enolase protein for tick vaccine development. The exact mechanism of the recently identified enolase protein from the H. longicornis Jeju strain remains poorly understood. Enolase plays a crucial role in glycolysis, the metabolic process that converts glucose into energy, and is essential for the motility, adhesion, invasion, growth, and differentiation of ticks. In this study, mice were immunized with recombinant enolase, and polyclonal antibodies were generated. Western blot analysis confirmed the specific recognition of enolase by the antiserum. The effects of immunization on tick feeding and attachment were assessed. Adult ticks attached to the recombinant enolase-immunized mice demonstrated longer attachment time, increased bloodsucking abilities, and lower engorgement weight than the controls. The nymphs and larvae had a reduced attachment rate and low engorgement rate compared to the controls. Mice immunized with recombinant enolase expressed in Escherichia coli displayed 90% efficacy in preventing tick infestation. The glycolytic nature of enolase and its involvement in crucial physiological processes makes it an attractive target for disrupting tick survival and disease transmission. Polyclonal antibodies recognize enolase and significantly reduce attachment rates, tick feeding, and engorgement. Our findings indicate that recombinant enolase may be a valuable vaccine candidate for H. longicornis infection in experimental murine model.

• Structural Engineering and Mechanics
• /
• v.88 no.2
• /
• pp.159-168
• /
• 2023

Cost-effective high precision hybrid elements are presented in a hierarchical form for dynamic analysis of plates. The costs associated with controlling the vibrations of ferromagnetic plates can be minimized by adequate determination of the amount of electric current and magnetic field. In the present study, the effect of magnetic field and electric current on nonlinear vibrations of ferromagnetic plates is investigated. The general form of Lorentz forces and Maxwell's equations have been considered for the first time to present new relationships for electromagnetic interaction forces with ferromagnetic plates. In order to derive the governing nonlinear differential equations, the theory of third-order shear deformations of three-dimensional plates has been applied along with the von Kármán large deformation strain-displacement relations. Afterward, the nonlinear equations are discretized using the Galerkin method, and the effect of various parameters is investigated. According to the results, electric current and magnetic field have different effects on the equivalent stiffness of ferromagnetic plates. As the electric current increases and the magnetic field decreases, the equivalent stiffness of the plate decreases. This is a phenomenon reported here for the first time. Furthermore, the magnetic field has a more significant effect on the steady-state deflection of the plate compared to the electric current. Increasing the magnetic field and electric current by 10-times results in a reduction of about 350% and an increase of 3.8% in the maximum steady-state deflection, respectively. Furthermore, the nonlinear frequency decreases as time passes, and these changes become more intense as the magnetic field increases.

• Geomechanics and Engineering
• /
• v.35 no.6
• /
• pp.603-615
• /
• 2023

Population growth and urbanization prompted engineers to propose more sophisticated and efficient transportation methods, such as underground transit systems. However, due to limited urban space, it is necessary to construct these tunnels in close proximity to existing infrastructure like high-rise buildings and bridges. Battered piles have been widely used for their higher stiffness and bearing capacity compared to vertical piles, making them effective in resisting lateral loads from winds, soil pressures, and impacts. Considerable prior research has been concerned with understanding the vertical pile response to tunnel excavation. However, the three-dimensional effects of tunnelling on adjacent battered piled foundations are still not investigated. This study investigates the response of a single battered pile to tunnelling at three critical depths along the pile: near the pile shaft (S), next to the pile (T), and below the pile toe (B). An advanced hypoplastic model capable of capturing small strain stiffness is used to simulate clay behaviour. The computed results reveal that settlement and load transfer mechanisms along the battered pile, resulting from tunnelling, depend significantly on the tunnel's location relative the length of the pile. The largest settlement of the battered pile occurs in the case of T. Conversely, the greatest pile head deflection is caused by tunnelling near the pile shaft. The battered pile experiences "dragload" due to negative skin friction mobilization resulting from tunnel excavation in the case of S. The battered pile is susceptible to induced bending moments when tunnelling occurs near the pile shaft S whereas the magnitude of induced bending moment is minimal in the case of B.

• Structural Engineering and Mechanics
• /
• v.89 no.1
• /
• pp.1-11
• /
• 2024

This article introduces a novel analytical model for examining the impact of porosity on shear correction factors (SCFs) in functionally graded porous beams (FGPB). The study employs uneven and logarithmic-uneven modified porosity-dependent power-law functions, which are distributed throughout the thickness of the FGP beams. Additionally, a modified exponential-power law function is used to estimate the effective mechanical properties of functionally graded porous beams. The correction factor plays a crucial role in this analysis as it appears as a coefficient in the expression for the transverse shear stress resultant. It compensatesfor the assumption that the shear strain is uniform across the depth of the cross-section. By applying the energy equivalence principle, a general expression for static SCFs in FGPBs is derived. The resulting expression aligns with the findings obtained from Reissner's analysis, particularly when transitioning from the two-dimensional case (plate) to the one-dimensional case (beam). The article presents a convenient algebraic form of the solution and provides new case studies to demonstrate the practicality of the proposed formulation. Numerical results are also presented to illustrate the influence of porosity distribution on SCFs for different types of FGPBs. Furthermore, the article validates the numerical consistency of the mechanical property changesin FG beams without porosity and the SCF by comparing them with available results.

• Structural Engineering and Mechanics
• /
• v.89 no.1
• /
• pp.33-46
• /
• 2024

The present research delves into the analysis of nonlinear free and forced vibrations of porous functionally graded (FG) shallow shells reinforced with oblique stiffeners, which are embedded in a nonlinear elastic foundation (NEF) subjected to external excitation. Two distinct types of PFG shallow shells, characterized by even and uneven porosity distribution along the thickness direction, are considered in the research. In order to model the stiffeners, Lekhnitskii's smeared stiffeners technique is implemented. With the stress function and first-order shear deformation theory (FSDT), the nonlinear model of the oblique stiffened shallow shells is established. The strain-displacement relationships for the system are derived via the FSDT and utilization of the von-Kármán's geometric assumptions. To discretize the nonlinear governing equations, the Galerkin method is employed. The model such developed allows analysis of the effects of the stiffeners with various angles as desired, in addition to the quantitative investigation on the influence of the surrounding nonlinear elastic foundations. To numerically solve the problem of vibrations, the 4th-order P-T method is used, as this method, known for its enhanced accuracy and reliability, proves to be an effective choice. The validation of the present research findings includes a comprehensive comparison with outcomes documented in existing literature. Additionally, a comparative analysis of the numerical results against those obtained using the 4th Runge-Kutta method is performed. The impact of stiffeners with varying angles and material parameters on the vibration characteristics of the present system is also explored. The researchers and engineers working in this field may use the results of this study as benchmarks in their design and research for the considered shell systems.

• Clinical and Experimental Vaccine Research
• /
• v.12 no.4
• /
• pp.304-312
• /
• 2023

Purpose: Due to the many problems with commercially available vaccines, the production of effective vaccines against brucellosis is a necessity. The aim of this study was to evaluate the immune responses caused by the chimeric protein consisting of trigger factor, Bp26, and Omp31 (TBO) along with aluminum hydroxide (AH/TBO) and selenium (Se/TBO) nanoparticles (NPs) as adjuvants in mouse model. Materials and Methods: Recombinant antigen expression was induced in Escherichia coli BL21 (DE3) bacteria using IPTG (isopropyl-d-1-thiogalactopyranoside). Purification and characterization of recombinant protein was conducted through NiFe₃O₄ NPs, sodium dodecyl sulfate-polyacrylamide gel electrophoresis, and Western blot. NP characteristics, including morphology and particle size, were measured in vitro. The recombinant TBO was loaded on to AH and Se NPs and were administered subcutaneously. After mice immunization, measurement of antibody titter and protection assay was performed. Results: The average sizes of AH and Se NPs were about 60 nm and 150 nm, respectively. The enzyme-linked immunosorbent assay results showed that the serum of mice immunized by subcutaneous injection with both nanovaccines produced significant immunoglobulin G (IgG) responses against the chimeric antigen. The results of TBO-specific IgG isotype (IgG2a/IgG1) analysis showed that both AH and Se NPs induced a type to T-helper immune response. In addition, the results of the challenge with the pathogenic strain of Brucella melitensis 16M showed that vaccinated mice with AH/TBO NPs indicated a higher reduction of bacterial culture than immunized mice with Se/TBO NPs and TBO alone. Conclusion: The results showed that AH NPs carrying chimeric antigen can be a promising vaccine candidate against brucellosis by producing protective immunity.

• Structural Engineering and Mechanics
• /
• v.89 no.3
• /
• pp.225-238
• /
• 2024

In this paper, a quasi-3D hyperbolic shear deformation theory for the bending responses of a functionally graded (FG) porous micro-beam is based on a modified couple stress theory requiring only one material length scale parameter that can capture the size influence. The model proposed accounts for both shear and normal deformation effects through an illustrative variation of all displacements across the thickness and satisfies the zero traction boundary conditions on the top and bottom surfaces of the micro-beam. The effective material properties of the functionally graded micro-beam are assumed to vary in the thickness direction and are estimated using the homogenization method of power law distribution, which is modified to approximate the porous material properties with even and uneven distributions of porosity phases. The equilibrium equations are obtained using the virtual work principle and solved using Navier's technique. The validity of the derived formulation is established by comparing it with the ones available in the literature. Numerical examples are presented to investigate the influences of the power law index, material length scale parameter, beam thickness, and shear and normal deformation effects on the mechanical characteristics of the FG micro-beam. The results demonstrate that the inclusion of the size effects increases the microbeams stiffness, which consequently leads to a reduction in deflections. In contrast, the shear and normal deformation effects are just the opposite.

• Advances in nano research
• /
• v.16 no.3
• /
• pp.231-249
• /
• 2024

When the amplitude of the vibrations is equivalent to that clearance, the vibrations for small amplitudes will really be significantly nonlinear. Nonlinearities will not be significant for amplitudes that are rather modest. Finally, nonlinearities will become crucial once again for big amplitudes. Therefore, the concrete panel system may experience a big amplitude in this work as a result of the high temperature. Based on the 3D modeling of the shell theory, the current work shows the influences of the von Kármán strain-displacement kinematic nonlinearity on the constitutive laws of the structure. The system's governing Equations in the nonlinear form are solved using Kronecker and Hadamard products, the discretization of Equations on the space domain, and Duffing-type Equations. Thermo-elasticity Equations. are used to represent the system's temperature. The harmonic solution technique for the displacement domain and the multiple-scale approach for the time domain are both covered in the section on solution procedures for solving nonlinear Equations. An effective data-driven solution is often utilized to predict how different systems would behave. The number of hidden layers and the learning rate are two hyperparameters for the network that are often chosen manually when required. Additionally, the data-driven method is offered for addressing the nonlinear vibration issue in order to reduce the computing cost of the current study. The conclusions of the present study may be validated by contrasting them with those of data-driven solutions and other published articles. The findings show that certain physical and geometrical characteristics have a significant effect on the existing concrete panel structure's susceptibility to temperature change and GPL weight fraction. For building construction industries, several useful recommendations for improving the thermo-mechanics' behavior of structural concrete panels are presented.