• 약학회지
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• 제48권1호
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• pp.82-87
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• 2004

Mungbean trypsin inhibitor (MBTI) was isolated and purified from Mung bean which has been used as a galenic and traditional food. MBTI and poly(ethylene glycol) were conjugated by using water soluble carbodiimide. We evaluated the therapeutic value of the MBTI and MBTI-PEG conjugate using animal models, sublethal septic shock model in guinea pig caused by pseudomonal elastase, shock model in rat caused by lipopolysaccharide, and the vascular permeability test by using pseudomonal elastase. In two shock model in guinea p Is and in rat, hypotesion shock was inhibited by pretreatment of MBTI. And also the vascular permeability caused by pseudomonal elastase reduced by pretreatment of MBTI. Also, therapeutic value of the MBTI-PEG conjugate was evaluated by using the sublethal septic shock model caused by pseudomonal elastase. The MBTI-PEG conjugate was more effective than native MBTI against pseudomonal elastase induced septic shock in guinea pig model.

• Structural Engineering and Mechanics
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• 제66권4호
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• pp.505-513
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• 2018

Steam flooding is widely used in heavy oil reservoir with coupling effects among the formation temperature change, fluid flow and solid deformation. The effective stress, porosity and permeability in this process can be affected by the multi-physical coupling of thermal, hydraulic and mechanical processes (THM), resulting in a complex interaction of geomechanical effects and multiphase flow in the porous media. Quantification of the state of deformation and stress in the reservoir is therefore essential for the correct prediction of reservoir efficiency and productivity. This paper presents a coupled fluid flow, thermal and geomechanical model employing a program (MATLAB interface code), which was developed to couple conventional reservoir (ECLIPSE) and geomechanical (ABAQUS) simulators for coupled THM processes in multiphase reservoir modeling. In each simulation cycle, time dependent reservoir pressure and temperature fields obtained from three dimensional compositional reservoir models were transferred into finite element reservoir geomechanical models in ABAQUS as multi-phase flow in deforming reservoirs cannot be performed within ABAQUS and new porosity and permeability are obtained using volumetric strains for the next analysis step. Finally, the proposed approach is illustrated on a complex coupled problem related to steam flooding in an oil reservoir. The reservoir coupled study showed that permeability and porosity increase during the injection scenario and increasing rate around injection wells exceed those of other similar comparable cases. Also, during injection, the uplift occurred very fast just above the injection wells resulting in plastic deformation.

• 한국자기학회지
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• 제2권2호
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• pp.91-98
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• 1992

$Co_{67}Fe_{4.5}Nb_{2}Si_{10}B_{15}$ 비정질합금리본에서 2단 어닐링이 자기특성에 미치는 영향을 조사 하였다. 고온인 $480^{\circ}C$ 이상에서 20분간 1단 어닐링한 리본을 저온인 $310^{\circ}C$에서 2시간 동안 2단으로 진공어닐링한 결과 보자력과 각형비는 1단 어닐링한 경우와 거의 비슷한 값들을 나타내었으나, 직류 및 교류투자율은 1단 어닐링에 비해 현저히 높아졌다. 2단 어닐링시 직류 및 1 kHz에서의 교류투자율의 최대치는 각각 약 290,000과 41,000으로서 1단 어닐링에 비해 30% 이상 증가하였다. 어닐링온도에 따른 자성의 변화는 3단계로 나누어 내부응력, 자구크기, cluster 및 결정상의 변화를 주요 요인으로 하여 고찰하였다.

• 한국지반공학회논문집
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• 제18권5호
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• pp.229-236
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• 2002

본 논문은 실용화된 지반개량용 마이크로시멘트 및 보통포틀랜드시멘트의 주입특성에 관한 연구로서 기초물성, 고결율, 침투성과 같이 실험적으로 주입재의 입도와 다짐정도를 조정하고, 주입대상 토사지반의 투수계수를 3종류로 변화시컥 약액주입의 주요 특성을 검토한 것이다. 주입재의 적용성을 평가하기 위하여 고결성 시험 및 침투성 시험을 실시한 결과, 모형토사지반의 상대밀도에 따른 투수계수를 $10^{-4}$~$10^{-2}$cm/sec로 변화시킨 경우, 마이크로시멘트는 투수 계수 $10^{-4}$cm/sec에서 유효고결율 75%, 침투주입율 86%로서 침투성 및 고결성이 우수한 결과를 나타낸 반면, OPC는 $10^{-2}$cm/sec에서 유효고결율 및 침투주입율이 50% 미만으로서 원활한 침투주입이 될 수 없음을 알 수 있었다. 댐 기초 지반 및 연약지반의 보강을 위해 주입재의 침투성이 요구되는 경우에는 마이크로시멘트가 적용성이 매우 우수한 것으로 판단된다. 동수지중 모형시험 결과 유속이 상대적으로 느린 경우 주입압이 높을수록, 완결형 주입재가 고결효과가 우수한 반면, 유속이 빠른 경우에는 완결형의 경우 주입재의 대부분이 외부로 유출되는 등 유효고결율이 매우 낮아 고결효과가 불량함을 알 수 있었다.

• 한국터널지하공간학회 논문집
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• 제12권5호
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• pp.349-358
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• 2010

대부분의 터널은 시간이 지남에 따라 유입량 증가, 작용수압의 변화 등 지하수의 영향을 받는다. 이러한 수리영향에 대응하기 위하여 터널 시공 시 지하수의 유입과 라이닝의 간극수압을 줄이기 위한 그라우팅을 적용한다. 본 연구에서는 효과적인 그라우팅을 위해 수치 해석결과를 바탕으로 다양한 그라우팅 조건에 대한 영향을 분석하였다. 그라우팅 영향 특성을 분석하기 위하여 그라우팅의 상대 투수계수 해석, 그라우팅의 두께, 그라우팅의 거리 등을 영향요소로 다르게 하였다. 해석결과는 지반하중, 수압, 라이닝 위치에 따른 수압, 라이닝 주변 수압분포, 유입량으로 나누어서 고찰하였다. 라이닝의 작용하는 지반 하중은 모든 조건에서 거의 동일했으며, 라이닝에 작용하는 수압은 그라우팅의 투수계수가 감소할수록, 두께가 증가할수록, 그라우팅 영역 거리가 가까울수록 감소하였다 유입량은 그라우팅 투수계수가 작을수록 감소하며, 그라우팅 두께와는 반비례한다. 본 그라우팅 영향 평가를 활용하여 지반 조건에 따른 그라우팅의 효과적인 적용을 할 수 있다.

• 한국세라믹학회지
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• 제34권10호
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• pp.1074-1082
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• 1997

Microstructure and permeability as a function of sintering temperature and composition were studied on the Ni$\delta$Cu0.4-$\delta$Zn0.6Fe2O4 ($\delta$=0, 0.1, 0.2, 0.3, 0.4) which was prepared by Cu2+ substitution for Ni2+ in Ni.0.4Zn0.6Fe2O4, then followed by 8 wt% CuO and 1wt% Bi2O3 as sintering aids. It was found that NiCuZn ferrite in which Cu2+ is substituted for Ni2+ is more effective in reduction of sintering temperature than Ni.0.4Zn0.6Fe2O4, containing CuO as a sintering aid. The specimen $\delta$=0.2 sintered at 90$0^{\circ}C$ for 2hr exhibited the highest initial permeability value ($\mu$o=280 at 1Mhz), but the real permeability decreased at the frequency under 10 MHz. EPMA analysis showed that Ni$\delta$Cu0.4-$\delta$Zn0.6Fe2O4 ($\delta$=0.4), sintered at 95$0^{\circ}C$ for 2hrs consisted of three phase regions of Ni.0.3Cu0.1Zn0.6Fe2O4 region, Cu and Bi liquid existed at the 3-point boundary, although the stabilization energy of Ni2+ is higher than that of Cu2+ in B site.

• Journal of the Korean Wood Science and Technology
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• 제25권3호
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• pp.37-42
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• 1997

This study was carried out to track the heated-air flows within the tree disk through measuring the distribution of wood temperatures during explosing the 7.5mm-thick Japanese cedar disk and to investigate the effects of the time for the first explosion cycle and the number of explosion cycles on the improvement of permeability of tree disk. If the tree disk are explosed when the temperatures of the shell and core of it are not equilibrium yet, all of the inflated airs in the shell after explosion don't flow out toward the autoclave and some of them flow into the core of which the air pressures are lower than those of the shell. It is very effective for the improvement of permeability of tree disk to make the first explosion cycle when the temperatures of the shell and the core equilibrate at the setting temperature of steam in the autoclave. The more tree disks were explosed under the same conditions of first explosion, the more their permeabilities were improved.

• Advances in concrete construction
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• 제13권 2호
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• pp.133-152
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• 2022

Ecological issues such as natural resource reduction and enormous waste disposals are increasingly leading in developing civilization toward sustainable construction. The two primary environmental issues are the depletion of natural resources and the disposal of trash in open landfills. Waste steel fiber (WSF) was investigated for usage as a cement-based concrete (CBC) constituent in this research. Recycling waste fibers both makes cement composites more long and cost-effective, also aids in pollution reduction. The objective of this study is to analyze the impacts of waste fiber on the fresh and mechanical features of concrete using recycled additives. A comparative research on the durability and mechanical qualities of fiber-reinforced concrete (FRC) constructed with natural aggregates was conducted for this aim. The obstacles to successful WSF recycling methods application in the building industry have been investigated, resulting that CBCs with these fibers make an economic and long lasting choice to deal with waste materials. The workability of fiber enhanced concrete was found to be comparable to that of normal concrete. Fibers have a considerable impact on the splitting tensile strength, flexural and compressive strength of recycled concrete. Fiber may enhance the water permeability. When the WSF content is 0.6 kg/m3, the water absorption is nearly half. Fibers would have no effect on its permeability.

• 한국지반환경공학회 논문집
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• 제5권4호
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• pp.57-63
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• 2004

강널말뚝(sheet pile)은 지하수의 침투저하 및 누수방지를 위하여 토목공사에서 폭넓게 이용되고 있으며, 특히 최근에는 강널말뚝의 지수효과로 인하여 오염된 지역의 지하수 흐름 또는 침출수의 차폐에도 사용되고 있다. 따라서 본 논문에서는 Z형 강널말뚝을 오염지역의 오염물질 차폐방법으로 적용할 경우에 대하여 살펴보았다. 이를 위하여 지수재의 도포조건과 강널말뚝의 시공조건 그리고 지반조건에 따른 Z형 강널말뚝의 연결부에 대한 실내 및 현장실험을 실시하였다. 실험결과, Z형 강널말뚝에 대한 모형실험을 통하여 지반조건에 따른 강널말뚝의 팽창지수재 도포방법, 강널말뚝 설치방법, 지반조건, 압력수두에 따른 투수특성을 파악하였으며, Z형 강널말뚝 연결부분의 효과적인 지수방안을 강구하였다. Z형 강널말뚝의 장기적인 지수효과는 강널말뚝 연결부의 자연적인 막힘 현상에 의하여 얻을 수 있으며 단기적인 지수효과는 지수재 도포에 의하여 효과적으로 얻을 수 있다. 본 실험결과로 인하여 Z형 강널말뚝이 오염지역의 차폐에 효과적으로 적용될 수 있는 것으로 나타났다.

• 한국막학회:학술대회논문집
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• 한국막학회 1997년도 추계 총회 및 학술발표회
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• pp.69-70
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• 1997

Polyimides and related polymers, when synthesized from aromatic monomers, have generally rigid chain structures resulting in a low gas permeability. The rigidity of polymer chains reduces the segmental motion of chains and works as a good barrier against gas transport. To overcome the limit of use as materials of gas separation membranes due to low gas permeability, block copolymers with the incorporation of flexible segments like siloxane linkage and ether linkage have been studied. These block copolymers have microphase-separated structures composed of microdomains of flexible poly(dimethylsiloxane) or polyether segments and of rigid polyimides segments. In case of rigid-flexible block copolymers, the characteristics of both phases for gas permeation are of great difference. The permeation of gas molecules occurs favorably through microdomains of flexible segments, whereas those of rigid segments hinder the permeation of gas molecules. Accordingly the increase of content of flexible segments in a rigid polymer matrix will increase the gas permeability of the membrane linearly. However, this prediction does not satisfy enough many experimental results and in particular the drastic increase of the permeability is observed in a certain volume fraction. It was proposed that the gas transport mechanism is dominated by diffusion rather than gas solubility in a certain content of flexible phase if solution-diffusion mechanism is adopted. However, the transition from solubility-dependent to diffusion-dependent cannot be explained by the understanding of mechanism itself. Therefore, we consider an effective chemical path which permeable phase can form in a microheterogenous medium, and percolation concept is introduced to describe the permeability transition at near threshold where for the first time a percolation path occurs. The volume fraction of both phases is defined as V$_{\alpha}$ and V$_{\beta}$ in block copolymers, and the volume of $\beta$ phase in the threshold forming geometrically a traversing channel is defined as V$_{\betac}$. The formation mechanism of shortest chemical channel is schematically depicted in Fig. 1.