• Journal of Conservation Science
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• v.36 no.5
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• pp.339-350
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• 2020

This study attempted to apply a hybrid technology that integrated mineral-based fillers and water-repellent agents to control the efflorescence that results from the use of inorganic binders, for the conservation treatment (surface finishing) of cultural heritage materials made up of stone. Herein, different types of mixing ratios of a filler (silica fume 3.4%) and a water repellent (silane-siloxane 1%) were selected for fabricating the inorganic binder, and it was determined that the ratio selected by weight is effective in controlling efflorescence substances. In addition, it was identified that the inorganic binder with the mixing ratio resulted in a higher compressive strength than the standard (20MPa), and the water permeability resistance was high with low water absorption. The result of ion elution from the bilder showed that a smaller number of ions was observed to affect the efflorescence (directly and indirectly) as compared to that of the control group, which was considered to be relatively stable.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.13 no.5
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• pp.2319-2324
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• 2012

In this paper, the design of asymmetric branch line couplers using artificial dielectric substrate (ADS) is described. The effective permittivity and permeability increase in ADS because of the lots of the inserted via-holes. So the physical length and width of transmission lines realized on ADS are reduced compared to the standard lines. This enables one to design size-reduced microwave circuits. As an instance in this work, an asymmetric branch line coupler with the ratio of 3:1 is designed at 2GHz. The designed coupler has a small size of 53.4% compared to the normal circuit while the same performances are preserved. A good agreement between the simulated and measured asymmetric power dividing ratio is shown. The measured loss is only less than 0.2dB, which is a very small value.

• Journal of the Korean institute of surface engineering
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• v.45 no.6
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• pp.248-256
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• 2012

A Pd-based hydrogen membranes for hydrogen purification and separation need high hydrogen perm-selectivity. The surface roughness of the support is important to coat the pinholes free and thin-film membrane over it. Also, The pinholes drastically decreased the hydrogen perm-selectivity of the Pd-based composite membrane. In order to remove the pinholes, we introduced various surface pre-treatment such as alumina powder packing, nickel electro-plating and micro-polishing pre-treatment. Especially, the micro-polishing pretreatment was very effective in roughness leveling off the surface of the porous nickel support, and it almost completely plugged the pores. Fine Ni particles filled surface pinholes with could form open structure at the interface of Pd alloy coating and Ni support by their diffusion to the membrane and resintering. In this study, a $4{\mu}m$ surface pore-free Pd-Cu-Ni ternary alloy membrane on a porous nickel substrate was successfully prepared by micro-polishing, high temperature sputtering and Cu-reflow process. And $H_2$ permeation and $N_2$ leak tests showed that the Pd-Cu-Ni ternary alloy hydrogen membrane achieved both high permeability of $13.2ml{\cdot}cm^{-2}{\cdot}min^{-1}{\cdot}atm^{-1}$ permation flux and infinite selectivity.

• Journal of the Korea institute for structural maintenance and inspection
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• v.15 no.4
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• pp.99-106
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• 2011

This study performed research for improvement on basic concept of PBD applying suitable design method before and after LB-DECK composition. According to study, in this case, before composition, it can reduce minuteness cracks by increasing bending tensile strength utilizing polymer concrete, can expect sensuous effect, improve durability as to low permeability, and was evaluated that can reduce covering depth according as it. Also, because LB-DECK baseplate that apply the empirical design method composite is superior load resistance ability than general baseplate, safety is increased, it is expected to secure constructibility and economic performance at the same time because reinforcement arrangement method and reinforcement amount are fixed even if span effective span is increased at ultimate strength design method application.

• Journal of the Korea institute for structural maintenance and inspection
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• v.15 no.4
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• pp.136-145
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• 2011

For a massive project related to building national industrial complexes on a soft ground applied to PVD after dredging and hydraulic fill, laboratory tests were carried out using undisturbed sample taken from various depth. Piezocone penetration and dissipation tests were carried out to assess horizontal coefficient of consolidation and initial stress in field. The ground consists of upper dredged fill and lower original clay layer having both similar marine clays. It should be, however, considered as multi-layered soft ground having different initial void ratio, initial water content, initial effective stress, and permeability and compressibility with directions. To assess initial stress of those soft layers in which have different stress history related to consolidation, CPTu test results, especially excess pore water pressure, were analyzed. It allows to find out distribution of excess pore water pressure and initial stress inner original clay layer.

• Journal of the Korean Ceramic Society
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• v.41 no.7
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• pp.541-547
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• 2004

Addition of large particles restrains densification by small particles in mixed particle systems. In the present study, large SiC whiskers or particles were introduced into small particles for restraining densification and the mixtures were sintered using yttrium aluminum garnet (Y$_3$A1$\sub$5/O$\sub$12/, YAG) as a sintering additive. By controlling the content of large SiC whiskers or particles and the applied pressure during sintering, porous SiC ceramics, with a porosity ranging from 0.3% to 39%, were fabricated. Porosity increased with increasing the content of restraining materials. SiC whiskers were more effective than large SiC partcles for restraining densification. Permeability of the porous SiC ceramics increased with increasing the porosity. Flexural strength decreased with increasing porosity. A noticeable increase in strain to failure was observed in the porous ceramics with a porosity ranging from 18% to 39%.

• Journal of Ginseng Research
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• v.42 no.4
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• pp.512-523
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• 2018

Background: 20(S)-Protopanaxadiol (20S-PPD) is a fully deglycosylated ginsenoside metabolite and has potent dermal antiaging activity. However, because of its low aqueous solubility and large molecular size, a suitable formulation strategy is required to improve its solubility and skin permeability, thereby enhancing its skin deposition. Thus, we optimized microemulsion (ME)-based hydrogel (MEH) formulations for the topical delivery of 20S-PPD. Methods: MEs and MEHs were formulated and evaluated for their particle size distribution, morphology, drug loading capacity, and stability. Then, the deposition profiles of the selected 20S-PPD-loaded MEH formulation were studied using a hairless mouse skin model and Strat-M membrane as an artificial skin model. Results: A Carbopol-based MEH system of 20S-PPD was successfully prepared with a mean droplet size of 110 nm and narrow size distribution. The formulation was stable for 56 d, and its viscosity was high enough for its topical application. It significantly enhanced the in vitro and in vivo skin deposition of 20S-PPD with no influence on its systemic absorption in hairless mice. Notably, it was found that the Strat-M membrane provided skin deposition data well correlated to those obtained from the in vitro and in vivo mouse skin studies on 20S-PPD (correlation coefficient $r^2=0.929-0.947$). Conclusion: The MEH formulation developed in this study could serve as an effective topical delivery system for poorly soluble ginsenosides and their deglycosylated metabolites, including 20S-PPD.

• Bulletin of the Korean Chemical Society
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• v.33 no.11
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• pp.3676-3680
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• 2012

An Epstein-Barr virus (EBV)-based plasmid contains the EBV nuclear antigen 1 (EBNA1) gene and EBV replication origin (oriP) sequence. Since EBNA1 (the only EBV-encoded protein) is combined with oriP, it is replicated simultaneously with chromosomal DNA in human, primate, and canine cells and is faithfully segregated at a stable copy number upon cell division. Consequently, it can be used to stably express gene inserts over a prolonged time in target cells. We have previously shown that the polyamidoamine (PAMAM) dendrimer can be surface-modified with L-arginine. Arginine is present at a high frequency in the transactivator of transcription (Tat) sequences of human immunodeficiency virus (HIV). It presents high membrane permeability and permits effective transfer of DNA inside the cells. In this study, we constructed two kinds of recombinant DNA by inserting the luciferase gene and enhanced green fluorescence protein (eGFP) gene as reporter genes into the pCEP4 plasmid vector. We measured dynamic light scattering (DLS) and zeta potential after preparing PAMAM-based cationic polymer/EBV-based plasmid complexes. We performed transfection of HEK 293 cell lines with the polyplexes, and monitored luciferase activity and green fluorescence protein (GFP) expression. Our results show that PAMAM-based cationic polymer/EBV plasmid complexes provide enhanced and sustained gene expression.

• Journal of Ocean Engineering and Technology
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• v.30 no.6
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• pp.505-519
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• 2016

If the seabed is exposed to high waves for a long period, the pore water pressure may be excessive, making the seabed subject to liquefaction. As the water pressure change due to wave action is transmitted to the pore water pressure of the seabed, a phase difference will occur because of the fluid resistance from water permeability. Thus, the effective stress of the seabed will be decreased. If a composite breakwater or other structure with large wave reflection is installed over the seabed, a partial standing wave field is formed, and thus larger wave loading is directly transmitted to the seabed, which considerably influences its stability. To analyze the 3-D dynamic response characteristics of the seabed around a composite breakwater, this study performed a numerical simulation by applying LES-WASS-3D to directly analyze the wave-structure-soil interaction. First, the waveform around the composite breakwater and the pore water pressure in the seabed and rubble mound were compared and verified using the results of existing experiments. In addition, the characteristics of the wave field were analyzed around the composite breakwater, where there was an opening under different incident wave conditions. To analyze the effect of the changed wave field on the 3-D dynamic response of the seabed, the correlation between the wave height distribution and pore water pressure distribution of the seabed was investigated. Finally, the numerical results for the perpendicular phase difference of the pore water pressure were aggregated to understand the characteristics of the 3-D dynamic response of the seabed around the composite breakwater in relation to the water-structure-soil interaction.

• KSBB Journal
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• v.10 no.4
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• pp.468-474
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• 1995

The disposable glucose bio-sensor using composite of CTA and PCL membrane was developed for measurement of glucose. The most effective membrane was composed of CTA/PCL(80/20, w/w) and glutaraldehyde one-step immobilization method ($10{\mu}m$ thickness) for glucose sensor gave the best result among various methods, considering oxygen permeability and electronic sensitivity. A scanning electron micrograph of the cross-section of a typical asymmetric CTA/PCL composite membrane showed that the membrane fused with a dense layer covered with a GOD-glutaraldehyde. Glucose oxidase immoblilized on the membrane showed the linearity between difference of absolute amperometric values and glucose concentrations within 7mM when the GOD immobilized electrode was used. About 35% of activity was remained after 8 days when the tyrosinase was immobilized on CTA/PCL (80/20) membrane.