• Korean Journal of Optics and Photonics
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• v.18 no.3
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• pp.208-215
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• 2007

A fiber-coupled laser-diode pumped ceramic Nd:YAG laser for compensating the thermal tensing effect was developed. The thermal tensing effect was compensated using a convex lens, which was 25 mm away from the laser rod, with a focal length of 30 mm and an effective clear aperture of 22 mm. Without a compensator, the laser output power decreased suddenly above a pump power of 6 W. Using a compensator, the laser output power increased linearly according to the pump power. The beam propagation factor $M^{2}$ was 2.4 under a pump power of 12 W.

• Physical Therapy Korea
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• v.20 no.4
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• pp.40-46
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• 2013

The purpose of this study was to determine which spatiotemporal gait parameters obtained during hemiplegic walking could be a predictive factor for the Timed Up and Go test (TUG). Two hundreds nine subjects who had suffered a stroke were recruited for this study. They were participated in two assessments; the TUG test and gait analysis. The relationship between the TUG test and spatiotemporal parameters was analyzed using Pearson's correlation coefficients. In addition, to predict the spatiotemporal gait parameters that correlated most with the TUG scores, we used multiple linear regression analyses (stepwise method). The results show that the normalized velocity was strongly correlated with the TUG performance (r=-.72, p<.001). Additionally, single support percentage (SSP), double support percentage (DSP), step time difference (STD), and step length difference (SLD) significantly were correlated with the TUG test. Normalized velocity, STD, DSP of affected side, and SSP of non-affected side explained 53%, 8%, 3%, 2%, of variance in the TUG test respectively. In conclusion, an increase in gait velocity and a decrease in STD would be effective indicators of improvement on the functional mobility in the stroke rehabilitation.

• Transactions of the Korean Society of Mechanical Engineers
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• v.13 no.5
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• pp.901-910
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• 1989

Corrosion fatigue crack propagation behavior of duplex stainless steel weldments in substitute ocean water was investigated to evalulate effects of micro-structural change and residual stresses. Fatigue crack propagation rate was found influenced markedly .alpha./.gamma. phase ratio but little by residual stresses. Fatigue crack propagation rate is higher in the corrosive environment than in room atmosphere. The crack propagation rate estimated by the measurement of striation spacing was higher than that, obtained by crack length measurement in low .DELTK.K region. At hight .DELTK.K region, however, both crack propagation rates were found to be identical.

• Journal of the Architectural Institute of Korea Structure & Construction
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• v.35 no.5
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• pp.145-152
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• 2019

In this study, rebar QTO(Quantity Take-Off) was quickly produced from the BIM model prepared by Revit in the early design phase, and the available premium rates were quantitatively presented. For this purpose, the amount of rebar calculated using the BuilderHub, which specializes in calculating rebar QTO, was analyzed according to various factors such as member type, rebar diameter, building size, item type, and order length, and the effect of each factor on the rebar QTO was determined. In addition, the BIM model generated on Revit was used to establish parameters and processes required to produce rebar QTO, and proposed a rebar premium rate and a stirrup/hoop premium rate based on the BuilderHub output results. Through this study, it is expected that a rapid and efficient comparative evaluation of rebar QTO will be possible according to various structural design alternatives in the early design phase.

• Animal Systematics, Evolution and Diversity
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• v.36 no.4
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• pp.347-353
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• 2020

Although sea slaters Ligia have a significant role in rocky shore habitats, their taxonomic entities have not been clearly understood. In this study, we investigated whether genetic variation inferred from a nuclear genetic marker, namely amplified fragment length polymorphism (AFLP), would conform to that of a mitochondrial DNA marker. Using both the mitochondrial DNA marker and the AFLP marker amplified by the six selective primer sets, we analyzed 95 Ligia individuals from eight locations from East Asia. The direct sequencing of mitochondrial 16S rRNA gene revealed three distinct genetic lineages, with 9.8-11.7 Kimura 2-parameter genetic distance. However, the results of AFLP genotyping analysis with 691 loci did not support those of mitochondrial DNA, and revealed an unexpectedly high proportion of shared polymorphisms among lineages. The inconsistency between the two different genetic markers may be explained by difference in DNA evolutionary history, for example inheritance patterns, effective population size, and mutation rate. The other factor is a possible genomic island of speciation, in that most of the genomic parts are shared among lineages, and only a few genomic regions have diverged.

• Fashion & Textile Research Journal
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• v.22 no.6
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• pp.826-833
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• 2020

When it is necessary to wear masks for long periods, such as during the current COVID-19 pandemic, the essential function of masks to prevent contamination (or transmission to others) as well as comfortableness are important. For this study, we used three-dimensional (3D) facial measurements of adult women to compile basic face shape data for designing comfortable and effective masks. This study analyzed the 3D facial data of 127 subjects in their 20s to 30s of the 6th Size Korea. Factor analysis of the survey data produced seven factors that formed the composition of adult female faces. These factors combined to produce three facial types: square (long face and a large lower middle face), oval (smallest central and lower body in the middle), and triangle (short face with a small central and lower large nose). These types reflect that the facial types of adult women show the differences in the nose angle, nose length, bitragion-subnasal arc, bitragion-menton arc. Therefore, properly fitting masks for fine dust particle filtration require 3D customization of a mask's breathing apparatus to fit differently shaped central and lower face parts that interfere with mask fit.

• BMB Reports
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• v.57 no.7
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• pp.318-323
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• 2024

Regulation of cell fate and lung cell differentiation is associated with Aminoacyl-tRNA synthetases (ARS)-interacting multifunctional protein 2 (AIMP2), which acts as a non-enzymatic component required for the multi-tRNA synthetase complex. In response to DNA damage, a component of AIMP2 separates from the multi-tRNA synthetase complex, binds to p53, and prevents its degradation by MDM2, inducing apoptosis. Additionally, AIMP2 reduces proliferation in TGF-β and Wnt pathways, while enhancing apoptotic signaling induced by tumor necrosis factor-α. Given the crucial role of these pathways in tumorigenesis, AIMP2 is expected to function as a broad-spectrum tumor suppressor. The full-length AIMP2 transcript consists of four exons, with a small section of the pre-mRNA undergoing alternative splicing to produce a variant (AIMP2-DX2) lacking the second exon. AIMP2-DX2 binds to FBP, TRAF2, and p53 similarly to AIMP2, but competes with AIMP2 for binding to these target proteins, thereby impairing its tumor-suppressive activity. AIMP2-DX2 is specifically expressed in a diverse range of cancer cells, including breast cancer, liver cancer, bone cancer, and stomach cancer. There is growing interest in AIMP2-DX2 as a promising biomarker for prognosis and diagnosis, with AIMP2-DX2 inhibition attracting significant interest as a potentially effective therapeutic approach for the treatment of lung, ovarian, prostate, and nasopharyngeal cancers.

• Journal of Korean Society of Transportation
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• v.35 no.4
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• pp.261-277
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• 2017

This study defines influencing sections as the part of the road section where passing vehicles are traveling with the lower speed compared to speed limit due to speed humps. The influencing section was divided into 3 parts; influencing section before the speed hump, interval section, and influencing section after the speed hump. This analysis focused on the changes of each part depending on installation types, vehicle types, and daytime or nighttime. For the interval section, especially, the ratio of distance traveled with lower speed than speed limit to interval section is defined as effective influencing section ratio to be analyzed. Vehicle speed profiles were collected with a speed gun to extract influencing section lengths. The survival analysis was applied and estimated survival functions are compared with each other by several statistical tests. As a consequence, the average length of influencing section on the 50m sequential speed humps was 75.3% longer during the deceleration than that of isolated speed hump, and 18.9% during the acceleration. The effective influencing section ratio for the 30m and 50m sequential speed humps had a small difference of 81.0% and 76.0% while the absolute values of the section that passing speed were less than the speed limit were longer on 50m sequential speed humps, each being 24.3m and 38.0m. Using the log rank test, it was evident that sequential speed humps were more effective to increase the length of influencing sections compared to the isolated speed hump. Vehicle type was the strong factor for influencing section length on the isolated speed hump, but daytime or nighttime was not the effective one. This research result can be used for improving the efficiency selecting the installation point of speed humps for road safety and estimating the standard of the distance between sequential speed humps.

• Journal of Ocean Engineering and Technology
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• v.4 no.2
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• pp.250-250
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• 1990

In this paper, fatigue tests were carried out at stress test levels of 461 MPa, 441 MPa, and 431 MPa by using smooth specimen of$2_{1/4}$ Cr-1 Mo steel with the stress ratio(R) of 0.05. The initiation, growth and coalescense process of the major cracks and sub-cracks among the fatigue cracks on the smooth specimen are investigated and measured under each stress level at a constant cycle ratio by the replica technique with optical microscope. Some of the important results are as follows: In spite of the difference of stress levels, the major crack data gather into a small band in the curve of surface crack length and crack depth against cycle ratio N/Nf. The sub-crack data, however, deviate from the band of the major crack. The growth rates, da/dN, of major and sub-crack plotted against the stress intensity factor range, ${\Delta}K$, have the tendency to be compressed on a relatively small band. But it is more effective to predict fatigue life through major cracks. The propagation behavior of surface microcracks on the smooth specimens coincides with that of the specimen having an artificial small surface defect or through crack.

• Toxicological Research
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• v.28 no.3
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• pp.159-164
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• 2012

Allergic skin inflammation such as atopic dermatitis (AD) is characterized by edema and infiltration with various inflammatory cells such as mast cells, basophils, eosinophils and T cells. Thymic stromal lymphopoietin (TSLP) is produced mainly by epidermal keratinocytes, as well as dermal fibroblasts and mast cells in the skin lesions of AD. Omega-3 polyunsaturated fatty acids in fish oil can reduce inflammation in allergic patients. Fermentation has a tremendous capacity to transform chemical structures. The antiinflammatory effects of fish oil have been described in many diseases, but the beneficial effects by which fermented olive flounder oil (FOF) modulates the allergic response is poorly understood. In this study, we produced FOF and tested its ability to suppress the various allergic inflammatory responses. The ability of FOF to modulate the immune system was investigated using a mouse model of AD. The FOF-treated group showed significantly decreased immunoglobulin E (IgE) and histamine in serum. Also, the increased TSLP expression was significantly inhibited in the FOF group; the FOF-treated group was not appreciably different from the hydrocort cream treatment group. In addition, FOF treatment resulted in a smaller spleen size with reduced the thickness and length compared to the induction group. Splenocytes from mice treated with FOF produced significantly less IFN-${\gamma}$, IL-4, T-box transcription factor (T-bet) and GATA binding protein 3 (GATA3) expression compared with the induction group. These results suggest that FOF may be effective in treating the allergic symptoms of AD. 5.