• 한국산학기술학회논문지
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• 제17권9호
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• pp.322-328
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• 2016

본 연구는 열대 유종류인 Metacylis tropica의 최적배양조건을 구명하기 위해 5일 동안 수온, 염분 및 먹이원인 미세조류의 효과를 조사하였다. M. tropica는 작고 투명한 난형의 피갑을 가지며, 피갑의 구강부 지름, 갑장 및 갑폭의 크기는 각각 $36.7{\mu}m$, $49.5{\mu}m$ 및 $44.5{\mu}m$였다. 수온별 실험에서, M. tropica의 최고밀도와 성장률은 수온 $30^{\circ}C$에서 각각 340.7 cells/mL와 1.1/day로 나타났다. 낮은 염분은 M. tropica의 성장에 악영향을 미쳤으며 염분 33 ppt에서 최고밀도가 840 cells/mL로 나타났다. 먹이실험에서, 먹이로 Isochrysis galbana를 공급하였을 때, 가장 높은 성장을 보였다(배양밀도, 413 cells/mL; 성장률, 1.2/day). 본 실험을 종합하여보면, M. tropica는 rotifer에 비해 작은 크기를 가지기 때문에 자어기에 입이 작은 어류의 초기먹이생물로 적합하며, 수온 $30^{\circ}C$, 염분 33 ppt에서 I. galbana를 먹이로 공급하는 것이 M. tropica의 대량배양을 위한 최적배양조건인 것으로 판단된다.

• 방사선산업학회지
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• 제6권2호
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• pp.189-197
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• 2012

This study was carried out to develop the improved useful mutants for yield or composition of stevia plants using the gamma ray or chemical mutagens treatments. The seeds of stevia 'Suwon No. 11' were irradiated up to 400 Gy of gamma ray. Chemical mutagens were treated on the seeds of the 'Suwon No. 11' using 0.07% colchicine, 10 mM sodium azide, or 10 mM NMU for various durations. The germination rate, and shoot and root growth of seedling were estimated at 30 days after gamma ray irradiation or chemical mutagen treatment, and the plant height, the number of branches, and leaf length and width were examined at 3 months after mutagenesis treatments. In the case of gamma ray treatments, the germination rate and early-stage growth were decreased as the increase of radiation dose, and the 50% lethal dose was found to be 200 Gy. the plant height was decreased as the increase of radiation dose, while the number of branches per plant and leaf length were increased. Leaf shape was modified to the relatively longer one compared to the control, which was identified more apparently at the treatments of higher than 150 Gy. In the treatment of chemical mutagens, the rate of germination and survival were decreased as the increase of incubation time. The 50% lethal dose for germination rate were identified as the conditions of the 15 hours incubation in 0.07% colchicine, the 4 hrs in 10 mM sodium azide, and the 2 hrs in 10 mM NMU, in the three chemical mutagens treatments. Chemical mutagens had no influence on shoot growth, while root growth was increased, especially as the incubation time was extended. The highest root growth occurred in the NMU treatment at 6 hrs incubation time. The plant height was decreased as the increase of incubation time in the chemical mutagens treatments. Among the chemical mutagens, NMU was the most effective to induce the mutants with long-shaped or the least lobed leaves.

• 한방안이비인후피부과학회지
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• 제31권1호
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• pp.22-31
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• 2018

Objectives : In this study, we investigated whether Astragali Radix Pharmacocupuncture (ARP) has an effective on the full thickness defect wound healing process of mouse. Methods : A total of 50 mice (ICR mouse, 7 week-old male) were divided into control group and ARP group. A single full thickness skin defect was made on the dorsal side of the each mouse using an 8mm diameter biopsy punch. Control group were treated with 0.2㎖ saline and ARP group were treat with 0.2ml ARP at 8 points around the wound every three days total 4 times during the experimental period. The change in wound size, contraction rate, healing rate, and epithelization rate was measured by digital images taken on days 3, 6, 9, and 13, and evaluated using a digital image analysis program. Tissues were collected for histological analysis, RT-PCR, and Western blot on days 3, 6, 9, and 15. Results : The results are as follows. ARP group accelerated the rate of wound contraction, wound healing and epithelization compared to the control group. ARP group showed the decrease of inflammatory cells in early inflammatory phase compared to the control group. ARP group upregulated PECAM-1 mRNA and protein expression compared to the control group. ARP group inhibited the scar width and area compared to the control group. Conclusions: ARP showed positive effects on wound healing through the inhibition of inflammatory reaction and increase of PECAM-1 expression related to the wound healing process.

• 한국자원식물학회지
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• 제20권5호
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• pp.471-474
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• 2007

종근크기에 따른 삼백초의 생산성을 구명하여 재배법 확립의 기초자료를 제공하고자 종근 직경 5mm 미만 등 4처리를 두어 시험한 결과, 출아는 종근직경 9mm 이상에서 빨리 출아되었으며, 최종 출아수도 종근 직경 6mm의 8.0개/$m^2$에 비하여 $84{\sim}109%$ 많았다. 줄기의 생육은 종근 직경 6mm에서 초장과 경태가 길거나, 굵어 양호한 경향이었으나, 분얼수는 종근크기가 클수록 많았다. 엽의 생육 중 상품엽수는 종근 직경 9mm 이상에서 많았으나, 엽장, 엽폭, 비상품엽수는 종근 크기 간에 차이가 인정되지 않았다. 상품 경엽의 건물중은 종근 직경 9mm 이상에서 높아, 종근 직경 6mm 대비 $35{\sim}37%$ 높았다. 이상의 결과에서 삼백초 재배 시 종근의 크기는 출아율과 경엽중이 많은 9mm가 가장 적합한 것으로 판단된다.

• 한국토양비료학회지
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• 제48권5호
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• pp.404-412
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• 2015

The slurry composting and bio-filtration (SCB) liquid manure has some obvious advantages including a good source of N, P and K, local availability, effective microorganism and the ability to improve soil properties. This study was conducted to evaluate the influence on the changes of soil chemical properties and yield of red pepper by fertigation cultivation with SCB application for 2 years. Red pepper was transplanted in early May in 2013 and 2014. The treatment with three replication was composed of 4 types as control (N 1.0), SCB 0.5N, SCB 1.0N, and SCB 2.0N standards of recommended nitrogen fertilizer ($19kg\;N\;10a^{-1}$). The fertigation cultivation which was installed the surface drip irrigation system was splitted 10 times as $2.5Mg\;10a^{-1}$ nutritional solution included with chemical fertilizer and SCB every 10 days during the cultivation. The height and width of pepper plant were 7.0% and 5.8% higher in SCB 2.0N treatment than that in control. The yield of red pepper increased with the increasing of SCB application rates from SCB 0.5N to 2.0N. The yield of SCB 1.0N was much better 10% in average than that of control, and there was significant differences among all treatments. pH of control soil after final harvest decreased to 6.1, however pH of SCB treated soils increased from 6.7 to 7.1 depending on SCB application rates. The Exch.-K contents of SCB treated soils were increased 13.7 to 56.9% after final harvest compared with control by $0.51cmol_c\;kg^{-1}$. Accordingly, these results showed that SCB 1.0N application rate as a recommended nitrogen level based on soil testing can be used as an alternative nitrogen management as well as plant nutrition for red pepper cultivation.

• 한국지반공학회논문집
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• 제34권11호
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• pp.57-70
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• 2018

본 논문에서는 항만구조물의 성능기반 내진설계 도입을 위해서 액상화를 포함하는 비선형 유효응력해석기법의 검증을 실시하였다. 중력식 케이슨안벽의 지진시 거동에 대해서 수치해석의 결과는 동적원심모형시험의 결과와 원형스케일로 직접 검증되었다. 중력식 안벽의 모형은 강성토조내에 지진시 과잉간극수압의 증가가 발생하는 포화 사질토 지반위에 조성되었으며, 원심가속도 60g하에서 높이 10m, 폭 6m의 케이슨 안벽을 묘사할 수 있다. 원심모형시험의 원형스케일과 동일하게 2차원 평면 변형율 조건하에서 비선형 유효응력 수치해석 모델을 구성하였다. 지반의 비선형 거동모델과 함께 Byrne의 액상화 모델을 사용하였으며, 경계요소를 적용하여 안벽과 지반의 분리거동을 묘사하였다. 검증결과, 안벽의 잔류변위를 포함하여 지반 및 안벽의 수평가속도와 안벽기초 하부 사질토 지반의 과잉간극수압 증가양상 모두 유사한 결과를 나타내었다.

• 한국전문물리치료학회지
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• 제26권3호
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• pp.67-75
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• 2019

Background: Stress urinary incontinence (SUI) is an involuntary leakage of urine from the urethra when intra-abdominal pressure increases, such as from sneezing, coughing, or physical exertion. It is caused by insufficient strength of the pelvic floor and sphincter muscles, resulting from vaginal delivery, obesity, hard physical work, or aging. The pelvic floor electrical stimulator is a conservative treatment generally used to relieve the symptoms of urinary incontinence. it recommended to applied before surgery is performed. Objects: The purpose of this study was to determine if the transcutaneous electrical stimulation (TCES) would be effective for the physiological symptoms and psychological satisfaction of women with SUI for an 8-weeks intervention. Methods: Easy-K is a specially designed user-friendly TCES. Five female who were diagnosed with SUI by a gynecologist but who did not require surgical intervention were included in this study. Intervention was implemented over an 8-week period. Outcome measures included vaginal ultrasonography, Levator ani muscle (LAM) contraction strength, incontinence quality of life (I-QOL), and female sexual function index (FSFI) questionnaires. Results: The bladder neck position significantly decreased across assessment time. Funneling index and urethral width significantly decreased after 8 weeks of intervention (p<.05). The bladder necksymphyseal distance and posterior rhabdosphincter thickness statistically increased and the anterior rhabdosphincter thickness showed a tendency to increase. All participants demonstrated a significant increase in the LAM contraction score across three assessment times (p<.05). Although the total score of the I-QOL did not show significant improvement, it steadily increased and among I-QOL subscales, only the "avoidance" subscale showed statistical improvements (p<.05). The total score of the FSFI statistically improved and the "desire" score significantly changed (p<.05). Conclusion: The TCES is recommended for women who want to apply conservative treatments before surgery and who have suffered from SUI in aspects of sexual function and quality of life.

• 한국산학기술학회논문지
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• 제20권5호
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• pp.27-35
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• 2019

본 연구는 땅밀림과 같이 예측할 수 없는 재해가 발생했을 때 신속 합리 효과적인 복구계획 수립에 기초자료를 제공하고자 수치지형도와 항공 LiDAR 자료를 이용하여 땅밀림 발생지역에서 변위 특성을 분석하였다. 이를 위해 본 연구에서는 항공 LiDAR 자료를 통하여 땅밀림 발생지점을 탐지하고 지형변화와 발생규모를 정량적으로 분석하였다. 그 결과 본 연구대상지는 국내 땅밀림 발생의 일반적 형태인 말굽형태로 나타났고, 붕괴방향은 북쪽이었다. 땅밀림 발생의 전체 면적은 약 2.5ha, 활락애는 길이 약 327.3m, 평균 폭 19.3m, 평균 깊이 8.6m로 분석되었다. 땅밀림이 대규모로 발생한 것은 아니지만, 도로가 위치한 인접사면에서 발생하여 옹벽 도로가 파손되는 등 큰 피해가 발생하였다. 땅밀림 발생지의 현장조사는 접근성, 안전성 등의 문제로 제한사항이 있지만 항공 LiDAR를 통하여 정확한 분석이 가능한 장점이 있었다. 그러나 항공 LiDAR는 비용이 많이 드는 단점이 있기 때문에 신속 지속 장기적인 모니터링에는 무인기에 LiDAR를 탑재하는 기술을 개발하여 이를 활용하는 것이 효율적이다. 이러한 땅밀림 발생지에서는 땅밀림의 이동방향, 규모 변화와 같은 정보를 지속적으로 획득해서 복구계획 수립 및 피해를 예방하는데 있어 활용해야한다.

• 감성과학
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• 제24권1호
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• pp.37-44
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• 2021

본 논문에서는 시야의 좌측과 우측만 가리는 시야 가리개를 이용하여 주변 시야 가림에 따른 집중력 향상 효과에 대한 연구를 수행하였다. 사용한 시야 가리개는 가로와 세로 5 cm × 4.8 cm 의 사다리꼴 모양으로 안경의 좌측과 우측에 고정 클립으로 부착할 수 있도록 하였다. 재질은 검정색의 폴리프로필렌(Polyprolylene)소재를 이용하였으며 클립을 포함하여 무게는 2.3 gram이었다. 건강한 20대 대학생 50명을 대상으로 15일간 시야 가리개를 사용하도록 한 후 정성평가와 정량평가를 수행하였다. 정성평가는 집중력 향상과 시야 가리개의 구조에 대한 설문조사로 진행하였다. 정량평가를 위하여 주의력 집중이 필요한 학습 동영상을 시청하도록 하면서 뇌파를 측정하였고 전두엽(frontal lobe) 영역인 F4 위치에 대한 Mid β 밴드(15~20Hz) 신호의 파워(power)와 ERD/S 분석을 수행하였다. 분석 결과 50명 중 80%인 40명이 시야 가리개를 착용하였을 때 집중력이 향상되었다고 보고하였다. 정량평가 결과 시야 가리개를 착용하고 동영상을 시청하였을 때 ERS peak(p=.023)와 ERD+ERS peak 값이 유의(p=.017)한 차이를 나타내었다. 결론적으로 좌측과 우측의 시야 가리개만을 사용하여도 집중력이 향상되는 결과를 도출하였다. 시야를 모두 가리는 덮개 형태 또는 시야의 상측과 하측을 가리지 않더라도 집중력을 향상시킬 수 있기 때문에 향후 간편한 방법으로 집중이 필요한 다양한 환경에서 활용이 가능할 것으로 기대된다.

• Journal of Dental Anesthesia and Pain Medicine
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• 제20권6호
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• pp.367-375
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• 2020

Background: Intraosseous anesthesia (IO) allows the anesthetic solution to be injected directly into the cancellous bone. The anesthetic solution immediately reaches the periapical region, and thus the axonal area of the nerve, where it can temporarily disable the sodium pump. The effect is felt almost without any time delay, and only a small amount of anesthetic solution is required. Methods: This study aims to investigate the efficacy of IO using the AnestoⓇ device after infiltration anesthesia (IA) and/or inferior alveolar nerve block anesthesia (IANB) failed to work in symptomatic irreversible pulpitis (hot tooth). The 33 patients included in the study were treated additionally with 1.7 ml articaine hydrochloride with 1:100,000 epinephrine hydrochloride (UltracainⓇ D-S, Sanofi-Aventis, Frankfurt, Germany) IO. Results: The electrical pulp test showed that 95.76% of the volunteers reacted positively to the combination of IANB or IA with the IO. In women, the additive IO was effective at 97.22%. In men, the IO led to pain elimination in 94.00% of cases. The duration of the IO was less than a quarter of an hour (13.03 min). The IO worked longer in women than in men (13.61 min vs. 12.33 min). Overall, more than every third tooth that needed trepanation was located in the posterior area of the mandible (36.4%). Treatment of hot teeth in this area was associated with an increased pulse rate and increased residual pain. There was a moderate correlation (Spearman-Rho [IRI] = 0.280) between the Visual Analog Scale (VAS) score and bone density, and a significant correlation (IRI = 0.612) between subjective residual pain and bone width. The IO resulted in a moderate, transient increase in the pulse rate by approximately 20 bpm. This is similar to the temporary increase in heart rate after conventional anesthesia techniques in non-preloaded patients and can be considered clinically irrelevant. Conclusion: IO with the AnestoⓇ device as an extension and deepening of local pain elimination is recommended for the treatment of hot teeth.