• The Korean Journal of Pain
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• v.9 no.1
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• pp.75-82
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• 1996

Background: Nerve blocks, including epidural analgesia, can be risky for terminal cancer pain patients in generally poor conditions. We performed this study to evaluate the efficacy of intravenous patient-controlled analgesia(PCA) to treat severe pain of terminally ill cancer patients during the last days of life. Methods: We explained the patient's poor general condition to relatives and received a written consent to administer PCA. The starting dose of opioid for PCA in cancer pain management was based on previous 24-hour dose. Previous 24-hour opioid dose was converted to intramuscular morphine equivalent. The concentration of opioid mixed into Basal Bolus $Infusor^{(R)}$ was controlled to allow for one half of the previous 24-hour equianalgesic dose to infuse continuously. Patients controlled their pain by pushing the PCA module themselves. Patients were observed by pain service team. Some discharged patients were treated at home until death. Results: Forty eight patients received PCA for last two years. The most common reason receiving a PCA was the patient's poor general condition(52.0%). The mean starting dose of PCA was $20.6{\pm}16.2$ mg of morphine. Over eighty percents of the patients were in good or tolerable state of analgesia. Half of the patients expired within one week. The mean duration of PCA was $8.7{\pm}7.0$ days. The problems during PCA were: difficulty in maintaining intravenous routes, early loss of mentality after starting PCA, hypotension and nausea. Conclusion: We concluded that PCA, if correctly, is an effective, relatively safe and readily controllable method of pain management in terminally ill cancer patients during the last days of life. For future considerations, terminal patients may expire at the comfort of their own homes after the resolution of legal problems regarding using opioid in home care.

• Journal of Gifted/Talented Education
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• v.13 no.3
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• pp.87-120
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• 2003

The purpose of this study is to verify empirically whether or not the linguistically creative problem-solving ability progress by developing and applying an enrichment learning program for the verbally gifted elementary school students. The total number of the verbally gifted students who participated in this study were 60 children. Half of them were subjects for evaluating the appropriateness of the enrichment learning program and the verbally creative problem-solving ability test developed by the researcher. The other half were divided into three groups for applying the teaching materials by Korean Educational Development Institute, the enrichment learning program by the present researcher, and the textbook enrichment program. The data were analyzed by the statistical method of repeated measures ANOVA. The results were as follows: First, the enrichment learning program developed by this researcher has greatly contributed to the advancement of verbally creative problem-solving ability. The program was especially effective in reading and writing, but not in speaking. second, the sub-category of reading includes factual, inferential·critical, and imaginary understanding. Among them, factual and imaginary understanding had not significantly advanced, while inferential·critical understanding had significant progression. Third, it was found that both logical and creative expression did not improve significantly by the enrichment learning program developed by the present researcher. Speaking is difficult to instruct. In conclusion, it was found that the systematic enrichment learning program was effective in developing language skills of the verbally gifted elementary school children. It was also proved to be more effective to teach them reading and writing together in everyday life. Also, it was turned out that continuous development of the enrichment learning program for the verbally gifted students is needed.

• Journal of the Korean Home Economics Association
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• v.29 no.3
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• pp.227-246
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• 1991

The study examined work and family life of married women employed in a manufacturing industry. Data were gathered from the use of face-to-face interview method from a sample of 230 married working women. The major findings of this study can be summarized as follows: (1) Most of the respondents found the work repetitive and unappealing, with the double burden of a paid work and housework. Thus, it is necessary for the government to implement social policies for married working women, such as establishment of various child care centers, part-time jobs, and dissemination of egalitarian sex-role attitudes. (2) More than half of the respondents were born in rural areas and immigrated to the urban sectors, forming a nuclear family structure. Most of these women were married with love, but some of them could not have a marriage ceremony because of the economic reasons. Thus, it may be necessary to increase the service centers to offer a free marital ceremony. (3) About 30% of the respondents answered they left their preschool aged children unattended, after dismissing from a kindergarden on a private institution. It was shown that working women, even though they were in charge of child-rearing, did not have an effective mechanism to control or protect their children while they were away from home. Most of them frequently used material compensations from their children in order to make up their absence at home. (4) It was found that the strategy for working women to decrease a dual-role conflict is to make a hierachy on the work they to do and to do only basic housework for everyday life and to do the rest of work on a off-day.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.3
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• pp.2059-2065
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• 2013

This goal of this research was to evaluate the cost-effectiveness of the National Cancer Screening Program (NCSP) for breast cancer in the Republic of Korea from a government expenditure perspective. In 2002-2003 (baseline), a total of 8,724,860 women aged 40 years or over were invited to attend breast cancer screening by the NCSP. Those who attended were identified using the NCSP database, and women were divided into two groups, women who attended screening at baseline (screened group) and those who did not (non-screened group). Breast cancer diagnosis in both groups at baseline, and during 5-year follow-up was identified using the Korean Central Cancer Registry. The effectiveness of the NCSP for breast cancer was estimated by comparing 5-year survival and life years saved (LYS) between the screened and the unscreened groups, measured using mortality data from the Korean National Health Insurance Corporation and the National Health Statistical Office. Direct screening costs, indirect screening costs, and productivity costs were considered in different combinations in the model. When all three of these costs were considered together, the incremental cost to save one life year of a breast cancer patient was 42,305,000 Korean Won (KW) (1 USD=1,088 KW) for the screened group compared to the non-screened group. In sensitivity analyses, reducing the false-positive rate of the screening program by half was the most cost-effective (incremental cost-effectiveness ratio, ICER=30,110,852 KW/LYS) strategy. When the upper age limit for screening was set at 70 years, it became more cost-effective (ICER=39,641,823 KW/LYS) than when no upper age limit was set. The NCSP for breast cancer in Korea seems to be accepted as cost-effective as ICER estimates were around the Gross Domestic Product. However, cost-effectiveness could be further improved by increasing the sensitivity of breast cancer screening and by setting appropriate age limits.

• Journal of Fashion Business
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• v.10 no.1
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• pp.132-147
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• 2006

The purpose of this study is to provide for the basic data useful to the effective production and marketing of the foundation garment befitting adult women's shapes and preferences, and thereby, help them improve their apparel life. For this purpose, 563 Korean women aged between 20-59 were sampled to survey their recognition and actual wearing condition of foundation garments and positively identify the factors affecting the practices and thereupon, determine the correlations among them by age group. The raw data of this study is processed by SPSS Win(10.1) and analyzed by using frequency, percentage, $x^2$-test, ANOVA, Duncan-test. The most of adult women were aware of their foundation size and the absolute majority of them wore brassieres, while a half of them used the girdles. The adult women had 5.7 Brassieres and 2.2 Girdles. The use of the foundation depended much on user's age or seasons. They had begun to wear Brassieres at their age of 15 on an average and Girdle around their age of 19 depending their individual needs. It has been found through this study that adult women's is actual wearing condition of foundation garments differ by age group, which may well suggest that foundation production need to consideration this age-wise practices when setting up their foundation production and marketing strategies.

• Journal of Power Electronics
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• v.16 no.4
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• pp.1469-1482
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• 2016

In hybrid energy storage systems, supercapacitors are usually connected in series to meet the required voltage levels. Equalizers are effective in prolonging the life of hybrid energy storage systems because they eliminate the voltage imbalance on cells. This study proposes a modularized equalizer, which is based on a combination of a half-bridge inverter, an inductor, and two auxiliary capacitors. The proposed equalizer inherits the advantages of inductor-based equalization systems, but it also offers unique merits, such as low switching losses and an easy-to-use control algorithm. The zero-voltage switching scheme is analyzed, and the power model is established. A fixed-frequency operation strategy is proposed to simplify the control and lower the cost. The switching patterns and conditions for zero-voltage switching are discussed. Simulation results based on PSIM are presented to verify the validity of the proposed equalizer. An equalization test for two supercapacitor cells is performed. An experimental hybrid energy storage system, which consists of batteries and supercapacitors, is established to verify the performance of the proposed equalizer. The analysis, simulation results, and experimental results are in good agreement, thus indicating that the circuit is practical.

• Asian Oncology Nursing
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• v.9 no.2
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• pp.95-103
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• 2009

Purpose: The purpose of this study was to examine nursing students' attitude toward death and perception on hospice care. Methods: The survey was performed with 277 nursing students in three universities in Daegu and Busan. The data was collected by questionnaires and were analyzed using descriptive statistics. Results: Regarding the attitude on death, 93.9% of the subjects had ever thought about death. They worried about separation and sadness with family (39.7%). About half (48.7%) of the subjects considered death as a final process of the life. With regard to the perception of hospice, 93% of the subjects heard about hospice through books or nursing courses (83.8%). The best hospice management institution was considered the one run by religious groups or non-profit organizations with government support (33.9%). Ideal model of hospice setting in Korea was hospital or institution specialized with hospice care (47.7%). The barriers the subjects thought to effective hospice care in Korea was the lack of the public consensus on the need for hospice program (37.9%). The average perceptions about the purpose of hospice care was 4.38, whereas, the average of the need of hospice care was 4.06. Conclusion: The findings of the study provides the basis for expanding nursing practice and education related to hospice care.

• Journal of Pharmaceutical Investigation
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• v.38 no.3
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• pp.151-155
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• 2008

Circadian variations of acebutolol and its main metabolite, diacetolol pharmacokinetics were studied after a single oral administration of acebutolol (10 mg/kg) to eight rabbits at 10 : 00 AM (in the morning) and 10 : 00 PM (at night). The plasma concentration profiles of acebutolol were significantly different (P<0.05) between 10 : 00 AM and 22 : 00 PM, suggesting circadian variations of pharmacokinetic behaviors. A significant circadian rhythm of pharmacokinetic parameters was noted in rabbits, showing higher total body clearance (CL/F), and lower the area under the plasma concentration-time curves (AUC) of acebutolol than that at night. The half-life ($t_{1/2}$) of acebutolol and diacetolol were also significantly shorter in the morning than at night (P<0.05). Metabolite-parent AUC ratio at night significantly decreased compared to in the morning, implying that night time could inhibit acebutolol metabolism than in the morning. From this study there was an administration-time difference of acebutolol pharmacokinetics in the rabbits. The optimized dosing regimen of acebutolol can be decided by considering circadian rhythm so that the effective therapies are established for patients.

• YAKHAK HOEJI
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• v.53 no.1
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• pp.34-40
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• 2009

The glycosylation of therapeutic glycoproteins can affect their efficacy, stability, solubility, and half-life. Analyzing the composition of monosaccharides, such as that of neutral and amino sugars, is the first step for elucidating the structure of glycan attached to glycoproteins. In the present study, neutral and amino sugars of lectin obtained from Maackia fauriei were analyzed using an enzyme-linked lectinsorbent assay (ELLA) and high-performance anion exchange chromatography with pulsed amperometric detection (HPAEC-PAD). Peroxidase-labeled lectins such as concanavalin A, Ricinus communis agglutinin, and soybean agglutinin were used for ELLA, since they specifically bind to the monosaccharide residue most frequently encountered in a glycan. The hydrosylate of lectin was prepared by treatment with trifluoroacetic acid, which resulted in the lectin mainly possessing the N-glycan consisting of 98.1 pmol Fuc, 342.1 pmol GlcN, 51.9 pmol Gal, 678.9 pmol Man, and 330.7 pmol Xyl. The present results demonstrate that ELLA and HPAEC-PAD are very effective methods for rapidly estimating the types and relative amounts of monosaccharides in intact glycoproteins.

• Journal of Families and Better Life
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• v.28 no.3
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• pp.113-127
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• 2010

This study explores the factors that affect the lottery purchasing intentions of university students. Self-administered questionnaires were completed by 504 students attending four universities in Kwangju South Korea. The conclusions are as follows: First, approximately 43% of respondents participated in at least one lottery purchase and the frequency of lottery purchases during the last 12 months was 4.84. Gender issues were considered since almost twice as many males reported lottery purchases. Second, males were affected by attitudes toward lotteries; females were affected by past behavior, subjective norms, and attitudes toward lotteries. It was hypothesized that the attitudinal message would change behavior for male students while the accurate information and the normative message would also be effective for female students. The fact that just about half of the respondents have previously participated in gambling vis-$\grave{a}$-vis lotteries shows consumer educators that lottery purchases by youth is a social policy issue in need of systematic and scientific attention.