• 한국농공학회논문집
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• 제58권3호
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• pp.71-80
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• 2016

The component-based modeling framework for agricultural water-resources management (COMFARM) is a user-friendly, highly interoperable, lightweight modeling framework that supports the development of watershed-specific domain components. The objective of this study was to evaluate the suitability of the COMFARM for the design and creation of a component-based modeling system of agricultural reservoir watersheds. A case study that focused on a particular modeling system was conducted on a watershed that includes the Daehwa and Dangwol serial irrigation reservoirs. The hydrologic modeling system for the study area was constructed with linkable components, including the modified Tank, an agricultural water supply and drainage model, and a reservoir water balance model. The model parameters were each calibrated for two years, based on observed reservoir water levels. The simulated results were in good agreement with the observed data. In addition, the applicability of the COMFARM was evaluated for regions where reservoir outflows, including not only spillway release but also return flow by irrigation water supply, substantially affect the downstream river discharge. The COMFARM could help to develop effective water-management measures by allowing the construction of a modeling system and evaluation of multiple operational scenarios customized for a specific watershed.

• 물과 미래
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• 제28권1호
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• pp.107-120
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• 1995

본 연구는 네팔의 Modi Khola 강 유역에 건설되는 Modi Khola 수력발전소의 취수구 구조물 및 침사지 구조물에 대한 수리모형실험 연구이다. 취수구 구조물은 축척이 1:20인 정상모형으로, 침사지 구조물은 수직방향 축척이 1:10, 수평방향 축척이 1:15인 왜곡모형으로 제작되었다. 본 실험에서는 이동상 모형이론에 의해 'Anthracite'($\rho_s$ =1.48)를 모형사로 선택하였다. 실험결과 취수구 구조물 부분에서는 세사영역의 유사퇴적을 막기 위해 적정한 높이의 guide wall 설치가 바람직하며, 효율적 배사를 위해 배사수문의 적절한 조작이 필요한 것으로 나타났다. 침사지 구조물 부분에서는 효율적인 침사를 위해 침사지내의 난류호흡을 억제시키는 설계가 요구되었고, 침사지내 퇴사를 처리하기 위하여 설치된 유출구측의 배사 파이프는 침사지 전영역의 배사를 효율적으로 수행하지 못하였으므로 최대 퇴사가 발생하는 지점 근처에 추가로 배사 파이프를 설치하는 것이 바람직하다. 또한 침사효율은 평균 약 95%로 관측되었는데, 비교적 좋은 침사지 설계라 판단된다.

• 공학교육연구
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• 제10권2호
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• pp.5-18
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• 2007

현장 실습의 목적을 달성하기 위한 가장 큰 주체는 공학교육과 관련된 학과임에도 불구하고, 공학교육의 주체들은 실제 시행 시 제반 문제점들을 이유로 현장실습의 필요성과 교육적 기대효과(성취동기 유발)의 중요성을 받아들이지 못하고 있는 실정이다. 본 연구는 한국과 프랑스의 현장실습의 수행제도를 비교 연구하고 그 문제점을 파악하여 한국 실정에 맞는 순환형 현장실습 제도를 위한 기본 틀을 제시 하고자 한다. 또한 실무능력에 맞는 단계적 기본 모형을 몇 가지 기본 단계로 제시하여 산업 현장에서 재교육 기간을 단축하여 현장으로 투입 될 수 있는 적응력을 갖춘 우수한 인력을 제공 받을 수 있는 현실적이며 미래지향적인 우수 인력을 양성할 수 있는 현장실습 체계를 마련 하고자 하였다. 이에 따라 본 연구에서는 13가지 개선을 위한 실천 체크리스트를 제시하고 순황형 시스템에 맞는 기본 실습 모형을 제시하였다.

• 한국물환경학회지
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• 제36권3호
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• pp.245-254
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• 2020

Water quality improvement projects are being implemented without predicting the effect of water quality improvement on Lake Sapgyo. As the method of selecting the target stream for the effective conduct of water quality improvement projects the method of rating the streams were studied. To build a stream grading method, 60 major streams in the Lake Sapgyo system were monitored. The selection method of rivers subject to priority management for water quality improvement was applied to the stream grading method using the Analytic Hierarchy Process (AHP). The analysis of importance by site by stream grading method revealed the following: water quality (36.0%), flow (26.1%), travel load (13.4%), TMDL density (12.0%), TMDL (8.9%), and area (3.7%). The pollution level of the river was scored by using the stream grading method, and the ranking of 51 streams was calculated. Based on this, the group was classified into six grades (A-F). Among the groups, the F and E groups were selected as the priority management streams. Cheonan-Cheon (Cheonan City) was selected as the first stream to establish water quality improvement measures in the Lake Sapgyo system, and Seowoo-Cheon (Dangjin City) was selected as the second site, and Oncheon-Cheon (Asan City) was selected as the third site. Each local government is expected to improve the water quality improvement effect with limited resources when establishing and implementing water quality improvement measures for the streams (F group, E group) to be managed in this study.

• Journal of Chest Surgery
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• 제36권9호
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• pp.633-637
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• 2003

일시적인 삼첨판 절개법은 좋은 시야를 제공하고 심실을 열지 않고 심실중격결손의 폐쇄수술을 할 수 있다. 그러나 대부분의 외과의는 삼첨판막의 폐쇄부전의 염려로 주저하게 된다. 특히 최근의 교과서에서는 일시적인 삼첨판 절개법은 장기성적의 발표가 예외적인 방법으로만 기술되어 있고 더 이상의 분석이나 기술이 되어 있지 않다. 대상 및 방법: 1985년부터 1994년까지 수술받은 11명으로부터 술 전의 자료, 술 후 경과, 최근 심초음파와 심전도를 토대로 후향적 연구를 시행하였다. 결과: 심초음파에서 삼첨판폐쇄부전은 없는 경우가 9명, 미세한(trivial) 경우가 2명이었고, 심전도상 의미있는 심전도블록은 없었다. 결론: 삼첨판 절개법은 심실중격결손의 폐쇄수술을 시행하는 데 안전하며 향상된 시야를 제공하는 데 효과적인 방법이며, 삼첨판 이상이나 심전도상에 나쁜 영향을 끼치지 않는다.

• 한국대기환경학회지
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• 제21권6호
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• pp.573-583
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• 2005

Fugitive dust, which is emitted in the ambient air without first passing through a stack or duct designed to control flow, is frequently generated by means of wind erosion from storage yards at Pohang Steel Wokrs. The size distribution of fugitive dust is mostly in the range of coarse particulate which is deposited as soon as emitted and less harm to human health; however $20\%$ of fugitive dust contains PM 10 known as one of most harmful airborne pollutant. Consequently, effective control and reduction of fugitive dust is strongly requested by the local society, but it is not easy so far because the generation and dispersion of fugitive dust highly depends on meteorological conditions, and it being occurred for irregularity. This research presented a fugitive dust control system for each meteorological condition by providing statistical prediction data obtained from a statistical analysis on the probability of generating the threshold velocity at which the fugitive dust begins to occur, and the frequency occurring by season and by time of the wind direction that can generate atmospheric pollution when the dispersed dust spreads to adjacent residential areas. The research also built a fugitive dust detection system which monitors the weather conditions surrounding storage yards and the changes in air quality on a real-time basis and issues a warning message by identifying a situation where the fugitive dust disperses outside the site boundary line so that appropriate measures can be taken on a timely basis. Furthermore, in respect to the spraying of water to prevent the generation of fugitive dust from the storage piles at the storage yard, an advanced statistical meteorological analysis on the weather conditions in Pohang area and a case study of fugitive dust dispersion toward outside of working field during $2002\∼2003$ were carried out in order to decide an optimal water-spraying time and the number of spraying that can prevent the origin of fugitive dust emission. The results of this research are expected to create extremely significant effects in improving surrounding environment through actual reduction of the fugitive dust produced from the storage yard of Pohang Steel Works by providing a high-tech warning system capable of constantly monitoring the leakage of fugitive dust and water-spray guidance that can maximize the water-spraying effects.

• The Korean Journal of Pain
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• 제26권4호
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• pp.336-346
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• 2013

Intrathecal drug delivery is an effective and safe option for the treatment of chronic pathology refractory to conventional pain therapies. Typical intrathecal administered drugs are opioids, baclofen, local anesthetics and adjuvant medications. Although knowledge about mechanisms of action of intrathecal drugs are every day more clear many doubt remain respect the correct location of intrathecal catheter in order to achieve the best therapeutic result. We analyze the factors that can affect drug distribution within the cerebrospinal fluid. Three categories of variables were identified: drug features, cerebrospinal fluid (CSF) dynamics and patients features. First category includes physicochemical properties and pharmacological features of intrathecal administered drugs with special attention to drug lipophilicity. In the second category, the variables in CSF flow, are considered that can modify the drug distribution within the CSF with special attention to the new theories of liquoral circulation. Last category try to explain inter-individual difference in baclofen response with difference that are specific for each patients such as the anatomical area to treat, patient posture or reaction to inflammatory stimulus. We conclude that a comprehensive evaluation of the patients, including imaging techniques to study the anatomy and physiology of intrathecal environment and CSF dynamics, could become essential in the future to the purpose of optimize the clinical outcome of intrathecal therapy.

• Membrane and Water Treatment
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• 제7권2호
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• pp.127-141
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• 2016

Electrodialysis (ED) is known to be a useful membrane process for desalination, concentration, separation, and purification in many fields. In this process, it is desirable to work at high current density in order to achieve fast desalination with the lowest possible effective membrane area. In practice, however, operating currents are restricted by the occurrence of concentration polarization phenomena. Many studies showed the occurrence of a limiting current density (LCD). The limiting current density in the electrodialysis process is an important parameter which determines the electrical resistance and the current utilization. Therefore, its reliable determination is required for designing an efficient electrodialysis plant. The purpose of this study is the development of a predictive model of the limiting current density in an electrodialysis process using response surface methodology (RSM). A two-factor central composite design (CCD) of RSM was used to analyze the effect of operation conditions (the initial salt concentration (C) and the linear flow velocity of solution to be treated (u)) on the limiting current density and to establish a regression model. All experiments were carried out on synthetic brackish water solutions using a laboratory scale electrodialysis cell. The limiting current density for each experiment was determined using the Cowan-Brown method. A suitable regression model for predicting LCD within the ranges of variables used was developed based on experimental results. The proposed mathematical quadratic model was simple. Its quality was evaluated by regression analysis and by the Analysis Of Variance, popularly known as the ANOVA.

• Asian Pacific Journal of Cancer Prevention
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• 제16권7호
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• pp.3061-3065
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• 2015

Background: Rac3, a member of the Rac family of small guanosine triphosphatases (GTPases), regulates a variety of cell functions, including the organization of the cytoskeleton, cell migration, and invasion. Overexpression of Rac3 has been reported in several human cancers. However, the role of Rac3 in lung cancer (LC) has not been determined in detail. The purpose of this study was to investigate the effect of silencing of Rac3 expression in human LC cells and the consequences for cell survival. Materials and Methods: Lentivirus small hairpin RNA (shRNA) interference techniques were utilized to knock down the Rac3 gene. Gene and protein expression was quantified by quantitative real-time polymerase chain reaction (qRT-PCR) and Western blotting. LC cell apoptosis was examined by annexin V-APC /propidium iodide staining. Results: Efficient silencing of Rac3 strongly inhibited A549 cell proliferation and colony formation ability, and significantly decreased tumor growth. Moreover, flow cytometry analysis showed that knockdown of Rac3 led to G2/M phase cell cycle arrest as well as an excess accumulation of cells in the G1 and S phase. Conclusions: Thus, functional analysis using shRNAs revealed a critical role for Rac3 in the tumor growth of LC cells. shRNA silencing of Rac3 could provide an effective strategy to treat LC.

• 한국수소및신에너지학회논문집
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• 제18권4호
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• pp.458-463
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• 2007

An experimental study on scale-up of Electro-electrodialysis(EED) to increase the efficiency of HI decomposition section in the IS(Iodine-Sulfur) process was carried out. The EED stack extends the effective area of the membrane to 20 times of that formerly used in a single EED unit cell. The experiment was carried out using HIx solution($HI:H_2O:I_2=1:8.4{\sim}9:1.85{\sim}1.9$) at $100^{\circ}C$ and various solution flow rates of 20, 30, 40 and 50 cc/min. The increased HI molality in catholyte after one-pass throughout from the EED stack was 3 mol/kg-$H_2O$, 2.2 mol/kg-$H_2O$, 2 mol/kg-$H_2O$ and 1.37 mol/kg-$H_2O$ at 20, 30, 40 and 50 cc/min, respectively. These values satisfied the target of HI molality(the increase of HI molality: 2 mol/kg-$H_2O$) in the IS process for hydrogen production of 20 L/hr.