• Progress in Medical Physics
• /
• v.28 no.2
• /
• pp.45-48
• /
• 2017

This paper evaluated the amount of radiation generated by wedge filters during radiation therapy using a high-energy linear accelerator, and the dose to the worker during wedge replacement. After 10-MV photon beam was irradiated with wedge filter, the wedge was removed from the linear accelerator, and the dose rate and energy spectrum were measured. The initial measurement was approximately 1 uSv/h, and the radiation level was reduced to 0.3 uSv/h after 6 min. The effective half-life derived from the dose rate measurement was approximately 3.5 min, and the influence of AI-28 was about 53%. From the energy spectrum measurements, a peak of 1,799 keV was measured for AI-28, while the peak for Co-58 was not measured in the control room. The peaks for Au-106 and Cd-105 were found only measurement was done without wedge removement from the linear accelerator. The additional doses received by the radiation worker during wedge replacement were estimated to be 0.08-0.4 mSv per year.

• Journal of Veterinary Clinics
• /
• v.34 no.1
• /
• pp.18-22
• /
• 2017

The aim of this study was to prove that the hypothesis of half dose (HD) allergen-specific immunotherapy (ASIT) in the treatment of canine atopic dermatitis (CAD) would result in a similar success rate compared to the standard dose (SD) ASIT. Clinical signs were evaluated using a third version of the Canine Atopic Dermatitis Extent and Severity Index (CADESI-03) prior to ASIT (day 0), at the end of induction (day 43), and at three month afterwards (day 90). Of the 18 atopic dogs, 12 dogs (SD group: 6; HD group: 6) had a good - excellent response to the house dust mites-specific immunotherapy. The efficacies of ASIT were 66.6% in both groups. The grades of reduction rate CADESI-03 were not different between two groups. Therefore, half dose protocol of house dust mites-specific immunotherapy is an effective and efficient method to treat CAD.

• Journal of Radiation Protection and Research
• /
• v.26 no.3
• /
• pp.291-298
• /
• 2001

The designed release rate of liquid effluents from radwaste treatment system should be calculated and evaluated during normal operation, including anticipated operational occurrence and be assured that the release concentration and off-site dose at unrestricted area do not exceed the limits of regulation. The expected annual release rate and off-site dose for the currently operating nuclear power plants in Korea had been calculated and evaluated using PWR-GALE and LADTAP-II which was based on USNRC Regulatory Guide 1.109. Recently, the MOST Notice 2001-2 related to release concentration and off-site dose at unrestricted area was revised to reflect the concept of ICRP-60. It is necessary for KORI 3&4 to re-calculate the release concentration and off-site dose and to compare these results with the limits of regulation. As the results of assessment, we confirmed that the release concentrations were less than its limits of MOST Notice 2001-2 and the off-site dose at unrestricted area using K-DOSE60 was 3.61E-03 mSv/yr to the age of five for the effective dose, and 4.10E-2 mSv/yr to thyroid of the age of five for the organ equivalent dose. We also confirmed the off-site dose was within the limits of MOST Notice 2001-2. Therefore, the release concentration and off-site dose re-evaluated at unrestricted area in KORI 3&4 were well below the regulation limits of MOST Notice 2001-2.

• Journal of radiological science and technology
• /
• v.39 no.3
• /
• pp.305-312
• /
• 2016

This study were compared with the direct measurement and indirect dose methods through various dose calculation in head and wrist. And, the modified equation was proposed considering equipment type, setting conditions, tube voltage, inherent filter, added filter and its accompanied back scatter factor. As a result, it decreased the error of the direct measurement than the existing dose calculation. Accordingly, diagnostic radiography patient dose comparison would become easier and radiogrphic exposure control and evaluation will become more efficient. The study findings are expected to be useful in patients' effective dose rate evaluation and dose reduction.

• Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
• /
• v.21 no.3
• /
• pp.371-381
• /
• 2023

Evaluating the effectiveness of the radiation protection measures deployed at the Centralized Radioactive Waste Management Facility in Ghana is pivotal to guaranteeing the safety of personnel, public and the environment, thus the need for this study. Radiagem^TM 2000 was used in measuring the dose rate of the facility whilst the personal radiation exposure of the personnel from 2011 to 2022 was measured from the thermoluminescent dosimeter badges using Harshaw 6600 Plus Automated TLD Reader. The decay store containing scrap metals from dismantled disused sealed radioactive sources (DSRS), and low-level wastes measured the highest dose rate of 1.06 ± 0.92 µSv·h^-1. The range of the mean annual average personnel dose equivalent is 0.41-2.07 mSv. The annual effective doses are below the ICRP limit of 20 mSv. From the multivariate principal component analysis biplot, all the personal dose equivalent formed a cluster, and the cluster is mostly influenced by the radiological data from the outer wall surface of the facility where no DSRS are stored. The personal dose equivalents are not primarily due to the radiation exposures of staff during operations with DSRS at the facility but can be attributed to environmental radiation, thus the current radiation protection measures at the Facility can be deemed as effective.

• Radiation Oncology Journal
• /
• v.14 no.1
• /
• pp.41-52
• /
• 1996

Purpose : This paper reports a dosimetric study of 88 patients treated with a combination of external radiotherapy and high dose rate ICR for FIGO stage IIB carcinoma of the cervix. The purpose is to investigate the correlation between the radiation doses to the rectum, external radiation dose to the whole pelvis, ICR reference volume, TDF BED and the incidence of late rectal complications, retrospectively. Materials and Methods : From November 1989 through December 1992, 88 patients with stage IIB cervical carcinoma received radical radiotherapy at Department of Radiation Oncology in Yonsei University Hospital. Radiotherapy consisted of 44-54 Gy(median 49 Gy) external beam irradiation plus high dose rate intracavitary brachytherapy with 5 Gy per fraction twice a week to a total dose of 30 Gy on point A. The maximum dose to the rectum by contrast(r, R) and reference rectal dose by ICRU 38(dr, DR) were calculated. The ICR reference volume was calculated by Gamma Dot 3.11 HDR planning system, retrospectively The time-dose factor(TDF) and the biologically effective dose (BED) were calculated. Results : Twenty seven($30.7\%$) of the 88 patients developed late rectal complications:12 patients($13.6\%$) for grade 1, 12 patients($13.6\%$) for grade 2 and 3 patients($3.4\%$) for grade 3. We found a significant correlation between the external whole pelvis irradiation dose and grade 2, 3 rectal complication. The mean dose to the whole pelvis for the group of patients with grade 2, 3 complication was Higher, $4093.3\pm453.1$ cGy, than that for the patients without complication, $3873.8\pm415.6$ (0.05$7163.0\pm838.5$ cGy, than that for the Patients without rectal complication, $0772.7\pm884.0$ (p<0.05). There was no correlation of the rate of grade 2, 3 rectal complication with the iCR rectal doses(r, dr), ICR reference volume, TDF and BED. Conclusion : This investigation has revealed a significant correlation between the dose calculated at the rectal dose by ICRU 38(DR) or the most anterior rectal dose by contrast(R) dose to the whole pelvis and the incidence of grade 2, 3 late rectal complications in patients with stage IIB cervical cancer undergoing external beam radiotherapy and HOR ICR. Thus these rectal reference points doses and whole pelvis dose appear to be useful Prognostic indicators of late rectal complication in high dose rate ICR treatment in cervical carcinoma.

• Journal of Radiation Protection and Research
• /
• v.33 no.4
• /
• pp.151-160
• /
• 2008

In Korean nuclear power plants (NPPs), two thermoluminescent dosimeters (TLD) were provided to workers who work in an inhomogeneous radiation field; one on the chest and the other on the head. In this way, the effective dose for radiation workers at NPPs was determined by the high deep dose between two radiation dose from these TLDs. This represented a conservative method of evaluating the degree of exposure to radiation. In this study, to prevent the overestimation of the effective dose, field application experiments were implemented using two-dosimeter algorithms developed by several international institutes for the selection of an optimal algorithm. The algorithms used by the Canadian Ontario Power Generation (OPG) and American ANSI HPS N13.41, NCRP (55/50), NCRP (70/30), EPRI (NRC), Lakslumanan, and Kim (Texas A&M University) were extensively analyzed as two-dosimeter algorithms. In particular, three additional TLDs were provided to radiation workers who wore them on the head, chest, and back during maintenance periods, and the measured value were analyzed. The results found no significant differences among the calculated effective doses, apart from Lakshmanan's algorithm. Thus, this paper recommends the NCRP(55/50) algorithm as an optimal two-dosimeter algorithm in consideration of the solid technical background of NCRP and the convenience of radiation works. In addition, it was determined that a two-dosimeter is provided to a single task which is expected to produce a dose rate of more than 1 mSv/hr, a difference of dose rates depending on specific parts of the body of more than 30%, and an exposure dose of more than 2 mSv.

• Asian Pacific Journal of Cancer Prevention
• /
• v.16 no.16
• /
• pp.7167-7170
• /
• 2015

Background: Although 3D image based brachytherapy is currently the standard of treatment in cervical cancer, most of the centres in developing countries still practice orthogonal intracavitary brachytherapy due to financial constraints. The quest for optimum dose and fractionation schedule in high dose rate (HDR) intracavitary brachytherapy (ICBT) is still ongoing. While the American Brachytherapy Society recommends four to eight fractions of each less than 7.5 Gy, there are some studies demonstrating similar efficacy and comparable toxicity with higher doses per fraction. Objective: To assess the treatment efficacy and late complications of HDR ICBT with 9 Gy per fraction in two fractions. Materials and Methods: This is a prospective institutional study in Southern India carried on from $1^{st}$ June 2012 to $31^{st}$ July 2014. In this period, 76 patients of cervical cancer satisfying our inclusion criteria were treated with concurrent chemo-radiation following ICBT with 9 Gy per fraction in two fractions, five to seven days apart. Results: The median follow-up period in the study was 24 months (range 10.6 - 31.2 months). The 2 year actuarial local control rate, disease-free survival and overall survival were 88.1%, 84.2% and 81.8% respectively. Although 38.2% patients suffered from late toxicity, only 3 patients had grade III late toxicity. Conclusions: In our experience, HDR brachytherapy with 9 Gy per fraction in two fractions is an effective dose fractionation for the treatment of cervical cancer with acceptable toxicity.

• Applied Chemistry for Engineering
• /
• v.7 no.5
• /
• pp.938-945
• /
• 1996

The present studies are to describe the grafting reaction of styrene in various solvents to polypropylene fabric by the simultaneous method using Co-60. The influence of various factors such as absorbed dose, dose rate, type of solvent, acid and multifunctional monomer were evaluated. At constant absorbed dose, the grafting yield was found to be higher at low dose rate. The initial rate of grafting was found to be proportional to a 0.56 power of dose rate. The inclusion of mineral acid in the grafting solution led to an increase in radiation grafting yield at almost all monomer concentration examined. Multifunctional monomer was also effective to increase grafting yield. The addition of both acid and multifunctional monomer was found to accelerate the grafting yield much more than the separate addition of two additives.

• Asian Pacific Journal of Cancer Prevention
• /
• v.17 no.1
• /
• pp.125-129
• /
• 2016

Background: Patients with differentiated thyroid cancers (DTC) who receive radioactive iodine-131 (RAI) are released from isolation when their dose rate is below the regulatory requirements. The purpose of this study was establish predicting factors for early release from the isolation facility after RAI administration in patients with DTC. Materials and Methods: This was a prospective study which included 96 (58 females and 38 males) patients with DTC who had received RAI from April 2013 till August 2015. The study was duly approved by the ethical committee of the institute. Patients who had complete information of primary tumor size (PTS), serum TSH, stimulated thyroglobulin level [sTg] with antibodies (IU/ml) at the time of RAI treatment were included. All had a normal serum creatinine level. To attain lower effective half-life good hydration and administration of soft laxative were ensured. Dose rate was measured (immediately, 24 h and 36 h) at 1 meter distance from anterior mid trunk and a dose rate <$50{\mu}Sv/h$ was considered as the releasing criterion. At 24 h 50 patients were released while the remaining 46 patients were released at 36 h. A post-ablative whole body scan (PA-WBIS) was performed 5-8 days after RAI ablation in all patients. Results: Patients released after 24 h were significantly younger, had smaller lesions with higher proportion of papillary cancer, lower sTg, lower sTg/TSH ratio and had received a lower dose of RAI as comapred to those who were discharged after 36 h. Serum TSH and gender were not found to have any significant correlation between two cohorts. ROC and multivariate analysis have shown age ${\leq}37years$, PTS ${\leq}3.8cm$, $RAI{\leq}150mCi$, $sTg{\leq}145ng/ml$ and $sTg/TSH{\leq}1.085$ as strong indepedent predictors for early release. Conclusions: We conclude that younger age (${\leq}37years$), smaller tumor size (${\leq}3.8cm$), lower RAI dose (${\leq}150mCi$), lower sTg (${\leq}145ng/ml$) and a lower sTg/TSH ratio (${\leq}1.085$) are significant independent predictors for release at 24 h after RAI treatment in DTC patients. Effective utilization of these factors could help the treating physicians to use limited number of internment facilities with higher throughput, lower cost and lower psychological stress to patients.