• Title/Summary/Keyword: Effective Concentration

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A Study on the Utilization of Yun Chun Andalusite as a Raw Material of High Alumina Refractories (II) -On the Concentration and Purification- (고 알루미나질 내화물 원료로서 연천산 홍주석의 이용에 관한 연구(II) -홍주석의 선광 및 정제-)

  • Ahn, Young-Pil;Choi, Long
    • Journal of the Korean Ceramic Society
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    • v.11 no.1
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    • pp.23-28
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    • 1974
  • 1. Stage crushing by jaw crusher, steel mortar, and ball mill in turn has shown an inclination to increase the distribution of andalusite in coarse particles as well as to increase that of micas in fine particles. 2. Water elutriation was effective for the removal of muscovite and magnetic separation was effective for that of Mg-Fe micas such as biotte and chlorite. The process of concentration and that of purification are diagramatized respectively as follows: Concentration; Raw andalusite${\lightarrow}$Crushing${\lightarrow}$Screening${\lightarrow}$Water elutriation${\lightarrow}$Magnetic separation Purification; Concentrated andalusite${\lightarrow}$Calcination${\lightarrow}$Ball milling${\lightarrow}$Screening${\lightarrow}$Water elutriation${\lightarrow}$Magnetic separation${\lightarrow}$Acid washing.

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Physiological and Psychological Effects of Viewing and Walking in Forest and Urban Area (산림과 도심에서의 조망 및 보행활동이 인체의 생리·심리에 미치는 효과)

  • Ji, Gyeong-Bae;Kim, Kyeong-Nam;Han, Gab-Soo
    • Journal of Environmental Science International
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    • v.21 no.5
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    • pp.605-611
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    • 2012
  • The purpose of this study is to analyze psychological and physiological effects accordance with viewing and walking in the forest and urban area. In the result of measurement of physiological reactions in nervous system, viewing of the forest had a calming effect on the nervous system by reducing blood pressure and heart rate. The other hand, viewing and walking in the urban area compared to the forest area raised stress by increasing blood pressure and heart rate. In addition, viewing in forest area was effective in stress relief by noticeable reduction of the amylase concentration. In contrast, walking in the urban area was also confirmed an increase of stress by increasing the concentration of the amylase. A viewing and walking in forest area was effective in alleviating depressed on anxiety, anger, fatigue and confusion.

Fresnel lens optics simulation with middle sized linear concentration without secondary optics (2차 광학계가 필요없는 프레넬 렌즈를 이용한 중집광 광학계 시뮬레이션)

  • Kang, Sung-Won;Kim, Yong-Sik;Sim, Chang-Ho
    • 한국태양에너지학회:학술대회논문집
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    • 2011.11a
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    • pp.27-33
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    • 2011
  • HCPV(High Concentrated PV) systems have well known for CPV market all over the world. Low concentration type silicon based modules have been introduced in the market. But low cost of standard flat silicon modules made them useless nowadays. High cost of compound semiconductor solar cell reduced cost effective cpv module production than that of recently silicon solar cell. In order to overcome increasing cost of CPV module, we study middle concentration type fresnel lens simulation using concentrated type silicon based solar cell. Linear type fresnel lens made production of CPV module without secondary optics such as light pipe or light tunnel. This type of fresnel lens design makes more cost effective solution for cpv niche market.

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Separation of Lipases Using Reversed Micelles (역미셀을 이용한 리파아제의 분리)

  • 최평호;류희욱이태호장용근
    • KSBB Journal
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    • v.6 no.4
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    • pp.337-344
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    • 1991
  • The liquid-liquid extraction of lipase A from Candide cylindracea and lipase B from porcine pancrease was carried out using reversed micellar organic solvents. Effects of various factors such as ionic strength, pH, and species and concentration of surfactant, on lipase solubilization were studied. A cationic surfactant cetyl-trimethyl ammonium bromide (CTAB) in isooctane/nhexanol(1:1) was found to be an effective solvent and its optimum concentration was 50 mM. KCl among various salts tested was the most effective and the efficiency of solubilization of lipase increased with decreasing the ionic strength of salts. The maximum activity and solubiliz ation of protein were obtained at pH 8. The stripping efficiency has a maximum value at pH 4 and increases with KCl concentration in the range of 0.2∼1.0 M. After the solubilization and stripping, the overall recovery efficiency of mass and specific activity of lipases was 62% and 66%, respectively.

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Suppressive Effects of Divalent Cations on Self-splicing Inhibition by Spectinomycin of Group 1 Intron RNA

  • Park, In-Kook
    • Journal of Microbiology
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    • v.37 no.4
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    • pp.243-247
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    • 1999
  • Effects of divalent cations on self-splicing inhibition by the antibiotic spectinomycin of the phage T4 thymidylate synthase intron (td) have been investigated. $Ca^{2+}$ ion at 1mM concentration suppressed splicing inhibition of spectinomycin by 10% and 50 ${\mu}M\;Co^{2+}$ ion also suppressed splicing inhibition of specinomycin by 10%. $Mg^{2+}$ ion at 6 mM concentration decreased splicing inhibition of spectinomycin by 42% while $Mn^{2+}$ ion decreased the splicing inhibition by 10%. $Zn^{2+}$ ion at 10 uM concentration lowered the splicing inhibition by spectinomycin of 15%. Of all divalent cations tested, $Mg^{2+}$ ion was the most effective in suppressing splicing inhibition by specinomycin whereas $Ca^{2+}$ ion was the least effective. The results suggest that spectinomycin may interact with specific and functional $Mg^{2+}$-binding sites within intron RNA that lead to a displacement of $Mg^{2+}$ essential for catalytic activity.

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Stabilization of Hydrogen Peroxide using Malonic Acid in Fenton and Fenton-like reactions (펜톤 및 펜톤 유사반응에서 말론산을 이용한 과산화수소의 안정화)

  • Kim, Jee-Eun;Ha, Tae-Wook;Kim, Young-Hun
    • Journal of Soil and Groundwater Environment
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    • v.18 no.7
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    • pp.25-31
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    • 2013
  • Hydrogen peroxide takes much of the cost for Fenton reaction applied for treatment of organic contaminants. Therefore, the effective use of hydrogen peroxide makes the technology more cost effective. The effective use of hydrogen peroxide is especially needed in the soil and groundwater remediation where complete mixing is not possible and it takes a long time for reactive species to transport to the fixed target compounds. Stabilization ability for hydrogen peroxide of malonic acid was evaluated in Fenton and Fenton-like reactions in this study. Malonic acid contributes on the stabilization of hydrogen peroxide by weak interaction between iron and the stabilizer and inhibiting the catalytic role of iron. The stabilization effect increased as the solution pH decrease below the $pK_{a1}$. The stabilization effect increased as the concentration of malonic acid increased and the effect was maximized at the malonic acid concentration of about ten times higher than the iron concentration. The model organic contaminant was successfully oxidized in the presence of the stabilizer but the degradation rate was slower than the system without the stabilizer. The stabilization effect was also proved in a Fenton-like reaction where magnetite and hematite were used instead of soluble iron species.

Multiple Shoot Formation from Flower Stalk Tissue Culture of Phalaenopsis Hybrids (팔레높시스 화경절편조직 배양에 의한 다신초 형성)

  • Choi, Jin Young;Koh, Jae Chul
    • FLOWER RESEARCH JOURNAL
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    • v.17 no.3
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    • pp.165-171
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    • 2009
  • This experiment was conducted to extend utility of in-vitro culture material stalk and to mass produce uniform plants in Phalaenopsis. The optimal concentration of hyponex medium and plant hormone were examined. The most effective concentration of the hyponex in the flower stalk tissue culture of Phalaenopsis was $4mg{\cdot}L^{-1}$. The most effective concentration of TDZ and BA on the formation of multiple shoots in Phalaenopsis flower stalk culture was $0.3mg{\cdot}L^{-1}$ and $5mg{\cdot}L^{-1}$, respectively. TDZ was more effective for formation of the shoots and multiple shoots than BA at the basic medium with hyponex $4g{\cdot}L^{-1}$.

The Effects of Donepezil, an Acetylcholinesterase Inhibitor, on Impaired Learning and Memory in Rodents

  • Shin, Chang Yell;Kim, Hae-Sun;Cha, Kwang-Ho;Won, Dong Han;Lee, Ji-Yun;Jang, Sun Woo;Sohn, Uy Dong
    • Biomolecules & Therapeutics
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    • v.26 no.3
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    • pp.274-281
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    • 2018
  • A previous study in humans demonstrated the sustained inhibitory effects of donepezil on acetylcholinesterase (AChE) activity; however, the effective concentration of donepezil in humans and animals is unclear. This study aimed to characterize the effective concentration of donepezil on AChE inhibition and impaired learning and memory in rodents. A pharmacokinetic study of donepezil showed a mean peak plasma concentration of donepezil after oral treatment (3 and 10 mg/kg) of approximately $1.2{\pm}0.4h$ and $1.4{\pm}0.5h$, respectively; absolute bioavailability was calculated as 3.6%. Further, AChE activity was inhibited by increasing plasma concentrations of donepezil, and a maximum inhibition of $31.5{\pm}5.7%$ was observed after donepezil treatment in hairless rats. Plasma AChE activity was negatively correlated with plasma donepezil concentration. The pharmacological effects of donepezil are dependent upon its concentration and AChE activity; therefore, we assessed the effects of donepezil on learning and memory using a Y-maze in mice. Donepezil treatment (3 mg/kg) significantly prevented the progression of scopolamine-induced memory impairment in mice. As the concentration of donepezil in the brain increased, the recovery of spontaneous alternations also improved; maximal improvement was observed at $46.5{\pm}3.5ng/g$ in the brain. In conclusion, our findings suggest that the AChE inhibitory activity and pharmacological effects of donepezil can be predicted by the concentration of donepezil. Further, $46.5{\pm}3.5ng/g$ donepezil is an efficacious target concentration in the brain for treating learning and memory impairment in rodents.

The effects of Hwangryunhaedoktang and herbs on Mouse neuroblastoma 2a cells damaged by hypoxia-reoxygenation (황연해독탕(黃連解毒湯)이 Hypoxia-reoxygenation에 의해 손상 받은 Mouse Neuroblastoma 2a Cells에 미치는 영향(影響))

  • Ahn, Sang-Hoon;Kim, Jong-Woo;Kang, Chul-Hun;Whang, Wei-Wan
    • Journal of Oriental Neuropsychiatry
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    • v.17 no.2
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    • pp.37-59
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    • 2006
  • Objective : This study was designed to asses the effect of Hwangryunhaedoktang and herbs on Mouse neuroblastoma 2a cells damaged by hypoxia-reoxygenation. Method : Mouse neuroblastoma 2a (N2a) cells were measured by MTT assay and LDH assay after 48h hypoxia and 6h reoxygenation. Mouse neuroblastoma 2a (N2a) cells were treated by Hwangryunhaedoktang and herbs. Result : 1. Hwangryunhaedoktang was effective on LDH assay of hypoxia and reoxygenation. 2. All of herbs were generally effective on LDH assay of hypoxia and reoxygenation. In LDH assay of hypoxia, the effects of herbs depended on concentration. In MTT assay of hypoxia, Coptidis Rhizoma and Gardeniae Fructus were effective. In MTT assay of reoxygenation most of herbs were not effective. But Phellodendri Cortex was effective in high concentration. Conclusion : The results imply that Hwangryunhaedoktang and all herbs of it nay have protective effect on dementia and aging.

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Antifungal Activity of Chaerophylline and Berberine Hydroxide Isolated from Corydalis Species

  • Tuli, Leepika;Jha, R.N.;Pandey, V.B.;Singh, U.P.
    • Mycobiology
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    • v.29 no.2
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    • pp.100-103
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    • 2001
  • Chaerophylline and berberine hydroxide, both being alkaloids, isolated from Corydalis chaerophylla and C. longipes respectively were assayed against spore germination of some fungi, e.g. Alternaria solani, A. brassicola, A. brassicicola, Helminthosporium penniseti, Helminthosporium sp., Heterosporium sp., Curvularia penniseti, C. maculens and C. palliscens. While chaerophylline inhibited spore germination of most of the fungi at 1000 ppm, being also effective at 50, 100, 200 and 500 ppm, berberine hydroxide was significantly effective at much lower concentration, i.e., 400 ppm against several fungi. This compound was also effective against some fungi at 50, 100, 150, 200 ppm. There was 100% inhibition of spore germination in several fungi at highest concentration of both the compounds. Some of the fungi showed similar results even at lower concentrations.

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