• Title/Summary/Keyword: Effect of alcohol

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The radioprotective effects of green tea and its fractions in Gamma-irradiated mice (감마선 조사 마우스에서 녹차 및 분획의 방사선 장해 경감 효과)

  • Kim, Se-ra;Lee, Hae-june;Kim, Sung-ho
    • Korean Journal of Veterinary Research
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    • v.43 no.4
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    • pp.633-639
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    • 2003
  • We investigated the effect of green tea and its fractions of alcohol and polysaccharide on jejunal crypt survival, endogenous spleen colony formation, and apoptosis in jejunal crypt cells of mice irradiated with high and low dose of gamma-irradiation. Jejunal crypts were protected by pretreatment of green tea (i.p.: 50 mg/kg of body weight, at 12 and 36 hours before irradiation., p.o.: 1.25% water extract, for 7days before irradiation, p<0.01) and alcohol and polysaccharide fractions showed no significant modifying effects. Green tea and its fractions administration before irradiation (i.p. at 12 and 36hours before irradiation) resulted in an increase of the formation of endogenous spleen colony (p<0.05). The frequency of radiation-induced apoptosis in intestinal crypt cells was also reduced by pretreatment of green tea (i.p. at 12 and 36 hours before irradiation, p<0.05., p.o. for 7days before irradiation, p<0.001) and its fractions (p<0.001). These results indicated that green tea might be a useful radioprotector, especially since it is a relatively nontoxic natural product. Further studies are needed to characterize better the promotion nature of green tea and its components.

Mechanical Properties of Concrete Pavement by Low Fraction of Macro Fiber (매크로 섬유의 저혼입에 따른 콘크리트 포장의 역학적 특성)

  • Choi, Sung-Yong;Park, Young-Hwan;Jung, Woo-Tai;Park, Jong-Sup
    • International Journal of Highway Engineering
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    • v.14 no.6
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    • pp.1-11
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    • 2012
  • PURPOSES : The purpose of the study was to examine dynamic features of concrete after mixing a little macro fiber with small aspect ratio and long length utilized for bridge, tunnel and shotcrete for tensile performance and crack control in domestic/overseas countries with cement concrete pavement mix. METHODS : Coarse aggregates with small aspect ratio and macro fibers with maximum length of approximately 32 mm are introduced in small quantities in the mix proportions of concrete pavement so as to prevent loss of the workability. Then, this study intends to evaluate the applicability of macro fibers in the mix proportions of concrete pavement by examining the basic construction performance, as well as the change of toughness, the equivalent bending strength and the flexural toughness index caused by compression, bending, tension and the flexural stress-displacement curve. RESULTS : As the results, in each kind of macro fiber, polyvinyl alcohol fiber and steel fiber displayed a good performance. CONCLUSIONS : In 0.2 and 0.3% of fiber contents, it is appeared that polyvinyl alcohol fiber has a large effect on improvement of tensile performance and steel fiber on improvement of deforming performance of bending stress.

Synthesis and Biocompatibility of PVA/NaCMC Hydrogels Crosslinked by Cyclic Freezing/thawing and Subsequent Gamma-ray Irradiation

  • Shin, Ji-Yeon;Jeong, Heeseok;Lee, Deuk Yong
    • Journal of Biomedical Engineering Research
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    • v.39 no.4
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    • pp.161-167
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    • 2018
  • Polyvinyl alcohol/sodium carboxymethyl cellulose (PVA/NaCMC) hydrogels were prepared by physical crosslinking (cyclic freezing/thawing) and gamma (${\gamma}$)-ray irradiation to evaluate the effect of NaCMC concentration (2~8 wt%) on the mechanical properties and the biocompatibility of the PVA/NaCMC hydrogels. The swelling rate of PVA/NaCMC hydrogels regardless of irradiation rose with increasing NaCMC content from 2 wt% to 8 wt%, while the gelation rate was the reverse. As the NaCMC content increased from 2 wt% to 6 wt%, the compressive strength of the hydrogels increased dramatically from $8.5{\pm}2.0kPa$ to $52.7{\pm}2.5kPa$ before irradiation and from $13.5{\pm}2.9kPa$ to $65.5{\pm}8.7kPa$ after irradiation. When 8 wt% NaCMC was added afterwards, the compressive strength decreased however. The irradiated PVA/NaCMC hydrogels containing 6 wt% NaCMC exhibited the tailored properties of the swelling rate of $118{\pm}3.7%$, the gelation rate of $71.4{\pm}1.3%$, the strength of $65.5{\pm}8.7kPa$, respectively, and no cytotoxicity was observed.

Studies on the Efficacies of Water Extract of Propolis (프로폴리스 물추출물의 약효연구)

  • 최혁재;심상범;김남재;김종우
    • Biomolecules & Therapeutics
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    • v.6 no.3
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    • pp.261-268
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    • 1998
  • Propolis is a lipophilic, natural product prepared by mixing the exudates collected from various plants by honeybees with beeswax for the purpose of using to seal hive walls and to strengthen the borders of combs. Because of its versatile bioactivities, propolis has been attracting many investigators'interest. But the pharmacological studies on propolis has, to date, been exclusively performed for an alcohol extract, there is few information of water extract. Therefore, in this study, we investigated the various effects of water extract of Chinese propolis. The water extract of propolis and its fractions of organic solvents showed strong antioxidative activities, especially ether and ethylacetate fractions, and reduced the lipid peroxidation of rat liver in viro. Additionally the ether fraction of propolis (10 mg/ml) inhibited the activity of hyaluronidase by 50%. In vivo, the water extract of propolis considerably decreased s-GOT, s-GPT and s-LDH activities which represent for the hepatotoxicity induced by $CCl_4$ in rats, and prolonged the MST (Medium revival tinge) and ILS (Increasing in MST over control) by 18% in mice which inoculated with sarcoma 180 ascites cells. These results suggest that the water extract of propolis has various bioactivities as well as the alcohol extract.

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Acupuncture treatment of drug addiction

  • Oh, Jin-Kyung;Chae, Youn-Byoung;Shim, In-Sop;Park, Hi-Joon;Lee, Hye-Jung
    • Advances in Traditional Medicine
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    • v.4 no.2
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    • pp.65-69
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    • 2004
  • Acupuncture as a therapeutic intervention has been widely used for treatment for many functional disorders, such as substances abuse and mental dysfunction. In general, acupuncture is known to be simple, economic; painless, non-traumatic, and without untoward reaction, being able to inhibit the abstinence syndrome. Although a number of studies on acupuncture have been reported, a few studies described acupuncture effect on drug addiction. Evidences suggest that substances abuses including nicotine, cocaine and alcohol are in part related to its effects on dopamine neurons in the reward pathways of the brain. The effects of acupuncture on drug addiction may be mediated through the neuronal cells within the limbic structures, which are known to be involved in rewarding properties of drug abuse. This essay reviews clinical and experimental evidences for its effectiveness on the drug addiction, and discusses a plausible explanation for the mechanism of acupuncture on substances abuse.

Preparation and Characterization of Poly(vinyl alcohol)/bentonite Nanocomposites Films with Modified Bentonites (개질된 벤토나이트가 혼입된 폴리비닐알코올/벤토나이트 나노복합 필름의 제조 및 특성분석)

  • Ji, Byung Chul;Yang, Seong Baek;Lee, Jungeon;Park, Jae Min;Han, Myung-Dong;Kim, Ui Ju;Yeum, Jeong Hyun
    • Textile Coloration and Finishing
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    • v.33 no.3
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    • pp.161-167
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    • 2021
  • Polymer nanocomposite is considered a great alternative to solve the limitations that exist in a simple combination material, as well as to produce multifunctional and high-performance results. In this research, PVA/bentonite nanocomposite films were prepared based on the presence or absence of modification of nano-clay(bentonite) a SUPERGEL® product, modification conditions and content, and the structural variation of the prepared PVA/bentonite nanocomposite films were examined. The effect of variations in the internal structure of the nanocomposite on mechanical and thermal properties was investigated. As a result of evaluating the thermal characteristics of the PVA/bentonite nanocomposite film based on the concentration of the modified bentonite, it was verified that the thermal characteristics and stability were improved because of interaction between the polymer and the modified nano-clay.

Effect of PVA Concentration on Strength and Cell Growth Behavior of PVA/gelatin Hydrogels for Wound Dressing

  • Kim, Soyeun;Lim, Hyunju;Kim, Sojeong;Lee, Deuk Yong
    • Journal of Biomedical Engineering Research
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    • v.41 no.1
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    • pp.1-7
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    • 2020
  • Polyvinyl alcohol (PVA)/gelatin hydrogels were prepared by repeating freezing/thawing three times to evaluate the influence of PVA concentration on the strength and the cell growth behavior of the PVA/gelatin hydrogels. The swelling rate of the PVA/gelatin hydrogels decreased with raising the PVA content from 6 wt% to 12 wt% due to the formation of 3-D network inside the hydrogel. No appreciable degradation of the hydrogels was detected. As the PVA content increased from 6 wt% to 12 wt%, the strength of the PVA/gelatin hydrogels increased drastically from 6.4±0.9 kPa to 46.6±9.0 kPa. The PVA/gelatin hydrogels did not show any evidence of causing cell lysis or toxicity, implying that the hydrogels are clinically safe and effective. Although the strength increased with increasing the PVA content, the PVA/gelatin hydrogels containing 8 wt% exhibited the fastest cell growth, which is highly suitable for wound dressing requiring fast healing regeneration.

Determination of Uranyl Nitrate with Several Ligands by Spectrophotometry

  • Showkat, Ali Md.;Zhang, Yu-Ping;Kim, Min Seok;Kim, Sang-Ho;Choi, Seong-Ho;Lee, Kwang-Pill
    • Analytical Science and Technology
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    • v.17 no.1
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    • pp.23-28
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    • 2004
  • Trace amount of uranyl (II) has been determined spectrophotometrically by measuring the optical density of the light blue yellowish coloured solutions formed by reaction between the metal ion and nicotinohydroxamic acid (NHx) in presence of different secondary ligands in strong isoamyl alcohol alkaline medium. The absorption maxima for both aqueous and extracted systems measured at their respective optimum pH were found to be 360 and 559 nm (DETA), 375 and 358 nm (EDA), 369 and 362 nm (piperidine), 354 and 341 nm (pyridine) and 363 and 336 nm (3 piperidine), 354 and 341 nm (pyridine) and 363 and 336 nm (3 - picoline), respectively at which Beer's law was obeyed. Effect of pH, reagent concentration, order of addition of reagent, time, temperature and solvent media on the absorption spectra have also been studied. Among the different systems studied, the shortest concentration range of uranyl(II) adhering to Beer's Law was 2.4 - 10.5 ppm observed for $UO_2(II)$ - NHx - DETA system in aqueous medium and also for iso amyl alcohol(IAA) extracted $UO_2$ - NHx - pyridine system was 2.4 - 7.8.

The Effect of Vacuum Films on Physicochemical and Microbiological Characteristics of Hanwoo (Korean Native Cattle)

  • Hwan Hee Yu;Sung Hun Yi;Sang-Dong Lim;Sang-Pil Hong
    • Food Science of Animal Resources
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    • v.43 no.3
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    • pp.441-453
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    • 2023
  • The objective of this study was to investigate the physicochemical and microbiological characteristics of round of Hanwoo by vacuum packaging film materials, polyvinylidene chloride (PVDC) and ethylene vinyl alcohol (EVOH). The packaged beef samples were stored in refrigerated conditions (2±1℃) for 12 weeks. Physicochemical analysis with pH, surface color, thiobarbituric acid reactive substances (TBARS) values, and volatile basic nitrogen (VBN) values and microbiological analysis with aerobic plate count (APC) and metagenomic analysis of packaged beef samples were performed. The pH and surface color did not change substantially during the 12 weeks and EVOH-packaged beef tended to be lower than those of PVDC-packaged beef. PVDC- and EVOH-packaged samples showed low TBARS and VBN values below standard limits. APC did not exceed 7 Log CFU/g for both samples during storage. In metagenomic analysis, Firmicutes and Lactobacillaceae were dominant phylum and family of the PVDC- and EVOH-packaged beef. In both packaged samples, Dellaglioa algida was the dominant species during storage, with the notable difference being the presence of Lactococcus piscium. Therefore, this study provided the information on the quality of vacuum-packaged beef according to different vacuum films for long-term refrigerated storage.

Development of photocatalytic PVA/$TiO_2$ nanofiber membrane by electrospinning and its application for Air Filtration

  • Linh, Nguyen Thuy Ba;Lee, Byong-Taek
    • Proceedings of the Materials Research Society of Korea Conference
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    • 2010.05a
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    • pp.38.1-38.1
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    • 2010
  • Nanofibers have a large potential in air filtration applications. In this work, we have developed a photocatalytic polyvinyl alcohol PVA/$TiO_2$ nanofibers membrane for the treatment of air filtration by using electrospinning method. PVA were electrospun into nanofibrous membranes and $TiO_2$ nanoparticles were loaded in PVA nanofibers in various contents from 10% (w/w) to 50% (w/w). The UV-Vis spectra were conducted for testing the existence of $TiO_2$ nanoparticles in PVA fibers. SEM analysis indicated that $TiO_2$ nanoparticles were loaded on the surface of PVA fibers and dispersed linearly along the fiber direction, which originated from the effect of polarization and orientation caused by high electric field. X-ray diffraction (XRD) was used to determine the crystalline of the membrane. Tensile strength was measured to evaluate the physical properties of the membrane. Therefore, our work suggested that PVA/$TiO_2$ nanofiber membrane has a potential application in air filtration area.

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