• Title/Summary/Keyword: Effect of alcohol

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Activities of Antioxidation and Alcohol Dehydrogenase Inhibition of Methanol Extracts from Some Medicinal Herbs (약용식물 추출물에 대한 항산화성과 알코올 탈수소효소 저해성 연구)

  • 문지숙;김선재;박윤미;황인식;김의형;박정욱;박인배;김상욱;강성국
    • Food Science and Preservation
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    • v.11 no.2
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    • pp.201-206
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    • 2004
  • The activities of antioxidation and alcohol dehydrogenase in hibitionin methanol extracts of thirty two medical herbs were tested using the method of DPPH activity, nitrite scavenging effect and alcohol dehydrogenase assay in vitro. In DPPH method, Eugenia caryophyllata, Thea sinensis, Paeonia suffruticosa, Alnus japonica showed over 90 % of free radical scavenging activities. The nitrite scavenging ability appeared Zanthoxylum bungeanum, Alnus japonica, Thea sinensis, Hovenia dulcis(cortex) and Illicium verum showed the high value. In connection with in vivo alcohol metabolism, thirteen medicinal herbs were screened for inhibition. As a reasult, we found significant inhibition of ADH by methanolic extracts of Glycyrrhiza uralensis, Pueraria thunbergiana(radix), Alnus japonica. These results indicate that the antioxidative effect was strongly related with alcohol dehydrogenase inhibitor; Thea sinensis and Alnus japonica.

Effect of Extraction Conditions on Yield and Quality of Extracts in Astragalas manbranaceus Bunge, Angelica gigas Nakai (황기, 당귀 추출물의 추출조건이 추출물의 수율 및 품질에 미치는 영향)

  • 이미숙;이근보;한명규;박상순
    • The Korean Journal of Food And Nutrition
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    • v.14 no.6
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    • pp.543-547
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    • 2001
  • The hot water extraction(HWE) has many problems such as a low extract yield and a reduced flagrance by excessive heating during concentration process notwithstanding it has been the general method to get the extract from the traditional chinese medicines Astragalas manbranaceus Bunge and Angelica gigas Nakai. For that reason, adopted the alcohol extraction In this research and got the good results of the 65% and 75% extract yield of Astragalas manbranaceus Bunge and Angelica gigas Nakai respectively, 15% and 36% increased compare with 50% and 39% (w/w) of HWE. The differences of extraction process between the HWE and alcohol extraction is substituting alcohol for water of extraction were concentrated at the relatively low temperature 90$\^{C}$ compare with the thermal extraction temperature 104$\^{C}$ . This alcohol extract, has the outstanding effect collecting the original fragrance at the low temperature. Applying this extract to starch syrup and beverage, expected that those contain a sufficient flavor as well as fragrance without artificial spices.

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Soybean Whey Composition and Alcohol Fermentation by Using Saccharomyces Cerevisiae (두부폐액(廢液)의 조성(組成) 및 Saccharomyces Cerevisiae를 이용(利用)한 Alcohol 발효(醱酵))

  • Choi, Mi-Ae;Choi, Kyoung-Ho
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.11 no.2
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    • pp.31-35
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    • 1982
  • Alcohol fermentation was carried out by using the yeast (S. cerevisiae) and soybean whey as the sole carbon source. The whey was gained form waste after manufacturing of soybean curd. The whey contained approximately one gram sugar per hundred mililter and the sugar was consisted of a 65 per cent of reducing sugar. However, it showed a low protein content of 43mg per the same volume. Ammonium sulfate showed the best effect on the generation of carbon dioxide among three kinds of tested nitrogen sourogen sources, potassium nitrate, urea and ammonium sulfate. Thus, fermentation was carried out with supplement of 2.0g ammonium sulfate to one liter of soybean whey. During fermentation continued for 48 hours, the maximum amount of ethanol 1.86g was produced from one liter of soybean whey. The ethanol fermentation utilized 81 and 94% of its initial sugar and protein contents, respectively.

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Effect of Solvent in the Dyeing System of Acid Dye/Human Hair (산성염료/모발 염색계에 있어서 용매의 효과)

  • Lee, Jin;Lim, Sun-Nye;Jung, Nam-Young;Lee, Woong-Eui;Choi, Chang-Nam
    • Textile Coloration and Finishing
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    • v.23 no.4
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    • pp.250-256
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    • 2011
  • In this work, the effects of surfactant and solvents, such as benzyl alcohol and n-propyl alcohol, on the human hair dyeing with acid dye was investigated including the amount of dyes in hair according to dyeing time, temperature, and pH. And the damage of dyed hair was assessed by water retention, protein release, and SEM images of the dyed hairs. By adding benzyl alcohol in acid dyeing, the dyeing rate was increased and the dyeing equilibrium was established at early stage. The water retention of the dyed hair was increased and the protein release of the dyed hair was decreased. Therefore the hair was damaged less during the dyeing.

(-) Epigallocatechin gallate restores ethanol-induced alterations in hepatic detoxification system and prevents apoptosis

  • Anuradha, Carani V;Kaviarasan, Subramanian
    • Advances in Traditional Medicine
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    • v.7 no.3
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    • pp.311-320
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    • 2007
  • The present study was designed to estimate the protective effect of (-) epigallocatechin gallate (EGCG) on ethanol-induced liver injury in rats. Chronic ethanol administration (6 g/kg/day ${\times}$ 60 days) caused liver damage that was manifested by the elevation of markers of liver dysfunction - aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase, lactate dehydrogenase, bilirubin and ${\gamma}$-glutamyl transferase in plasma and reduction in liver glycogen. The activities of alcohol metabolizing enzymes such as alcohol dehydrogenase and aldehyde dehydrogenase were found to be altered in alcohol-treated group. Ethanol administration resulted in the induction of cytochrome p450 and cytochrome-$b_{5}$ activities and reduction of cytochrome-c reductase and glutathione-S-transferase, a phase II drug metabolizing enzyme. Further, ethanol reduced the viability of isolated hepatocytes (ex vivo) as assessed by trypan blue exclusion test and induced hepatocyte apoptosis as assessed by propidium iodide staining. Treatment of alcoholic rats with EGCG restored the levels of markers of liver injury and mitigated the alterations in alcohol metabolizing and drug metabolizing enzymes and cyt-c-reductase. Increased hepatocyte viability and reduced apoptotic nuclei were observed in alcohol + EGCG-treated rats. These findings suggest that EGCG acts as a hepatoprotective agent against alcoholic liver injury.

Quality Properties of Gangha-ju Liquor According to the Preparation Method (제조방법에 따른 강하주의 품질 특성)

  • Yu, Young-Ju;Jung, Soon-Teck
    • Journal of the Korean Society of Food Culture
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    • v.18 no.2
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    • pp.111-122
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    • 2003
  • This studies were performed to develop a Korean traditional folk liquor namely Gangha-ju has been prepared at Bosung district in Korea, and manufacturing conditions and anti-oxidation activity and anti-microbial activity of Gangha-ju were investigated. Ethyl-alcohol 20% and 30% Gangha-ju were brewed with glutinous rice wine, distilled liquor and 6 herbs of ginger, cinnamon, etc. Chemical and physical properties of 30% Gangha-ju were acidity 0.22, pH 4.31, amino acidity 3.26, transmittance 59 and conductivity $911\;{\mu}s/m$, and 20% Gangha-ju were 0.43, 4.20, 6.26, 62 and $924\;{\mu}s/m$. Volatile flavor compounds of ethyl alcohol, acetic acid, butanol, n-amyl alcohol, iso-pentyl alcohol, ethyl acetate, butyl acetate, acetaldehyde and furfural were detected, and main aroma compounds of Gangha-ju were isopentyl alcohol and ethyl acetate. Anti-oxidation activity by DPPH method was evaluated 31.32%, and nitrite scavenging effect was 31.79%. Anti-microbial activity against several microorganisms was pronounced strong activity over a wide range of test organisms, and Leuconostoc mesenteroids and Salmonella Ttyphimurium, Staphylococcus epidermidis were found to be more sensitive to Gangha-ju than Escherichia coli and Aspergillus flavus.

The Effect of Personal Value on Drinking Motive: Focus on Undergraduate Student Drinkers (개인의 가치가 음주동기에 미치는 영향: 대학생 음주자를 중심으로)

  • Kim, Maeng-Jin
    • Journal of the Korean Society of Food Culture
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    • v.24 no.4
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    • pp.376-384
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    • 2009
  • The purpose of the present study was to examine the relationship between personal value and the motivation for drinking of Korean undergraduate student alcohol drinkers. Data were obtained from undergraduate students experienced in alcohol consumption in Seoul, Kyeonggi-do, and Kyeongsangnam-do. Trained researchers for this particular study conducted the survey and data from 208 students was analyzed using the SPSS package program. In this study, two personal values were examined: 'internal value' and 'external value', and four motives for drinking alcohol were identified: social motive, coping motive, enhancement motive, and conformity motive. The results of the present study showed that personal value had significant effects on the motives for drinking of Korean undergraduate student alcohol drinkers: 1) The internal value was significant on the coping motive and enhancement motive. 2) The external value was significant on the social motive. 3) Neither value was significant on the conformity motive. Based on the findings of the present study, personal value would be a useful variable in the field of alcoholic beverage marketing such as alcohol consumption, consumer behaviors and segmentation of the alcoholic beverage market.

The Effect of Selenium and Vitamin E on Activity of Enzyme Related to the Lipid Peroxidation in Rat with Alcohol Administration (식이내 Selenium과 Vitamin E가 Alcohol을 섭취한 흰쥐의 간 지질 과산화에 관련된 효소의 활성에 미치는 영향)

  • 김갑순;정승용;김석환
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.22 no.2
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    • pp.116-126
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    • 1993
  • The purposes of this study were to investigate the effect of seleniumc (Se) and vitamin E on activity of enzyme relevant to lipid peroxidation in alcohol administrated rats. Seventy two male rats of Sprague-Dawley strain weighing about 58~62g were divided into 12groups. The dietary Se levels were 0, 0.4 and 10mg and the dietary vitamin E levels were 0 and 150mg per kg diet, respectively. Alcohol-administrated groups received drinking water solution containing 10% of ethanol from the 3-weeks of experimental periods. The obtained experimental results are summarized as follow: The ${\gamma}$-GTP activity in plasma was higher in alcohol administrated groups and high selenium group (HSe) and low selenium group (LSe) than in control groups (CSe). The ${\gamma}$-GOT and GPT activities were higher in alcohol groups. The ${\gamma}$-GTP activity was significantly influenced by alcohol in LSe groups than in other groups. The glutathione peroxidase (GSH-Px) activity of plasma was significantly lower in LSe groups than HSe and CSe groups. The GSH-Px activity of microsomal and cytosolic fraction was slightly lower in alcohol groups and was about a half value lower in HSe and LSe groups than CSe groups. There was negative correlation between plasma Se level and GSH-Px activity of cytosolic fraction in HSe groups (r=- 0.662, p<0.001) and positive correlation in LSe groups (r=0.640, p<0.001). The GSH S-transferase activity in microsomal and cytosolic fraction was slightly higher in alcohol administrated but vitamin E nonadministrated groups, and significantly higher in LSe groups than in other groups. The catalase activity in mitochondria was lower in HSe than CSe groups, but rather higher in LSe groups. The superoxide dismutase (SOD) activity in cytosolic fraction of liver was not found any effect in all groups. The cytochrome P-450 was higher in alcohol groups, but significantly lower in HSe groups. In conclusion, the deficiency of Se and vitamin E develops the hyperoxidation of liver lipid through the increase of activity of enzyme related to the lipid peroxidation and alcohol administration appears to further increase of hyperoxidation of liver lipid.

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Effect of Leaf Mustard (Brassica juncea) on Lipid Metabolism of Rat with Chroethanol Administration (갓(Brassica juncea) 첨가식이가 만성적인 알콜 투여시 흰쥐의 지방대사에 미치는 영향)

  • 차연수;정복미
    • Korean Journal of Human Ecology
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    • v.1 no.1
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    • pp.94-102
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    • 1998
  • This study was undertaken to investigate the effects of mustard leaf diet on the lipid metabolism under chronic alcohol administration. Sprague-Dawley male rats were fed either AIN-76 diet(control), control with ethanol, AIN-76 diet plus 5% mustard leaf(mustard leaf), or mustard leaf with ethanol lot 30 days. On the 21st day, all of the rats were given an oral dose of ethanol and blood-ethanol concentration were monitored for the next 5 hours. Lipid and enzyme determinations in serum and liver were carried out after 30 days. The results obtained were summarized as following: 1) Supplementing 5% of mustard leaf did not recover the body weight loss due to chronic alcohol administration. 2) There were no significant differences in blood ethanol concentrations among the experimental groups. 3) Mustard leaf diet decreased the plasma total cholesterol, triglyceride levels increased due to the chronic alcohol administration, but not HDL-, LDL-cholesterol, and liver lipids. 4) Mustard leaf diet decreased ${\gamma}$ -GTP level increased by chronic alcohol administration. Overall, these data suggest that mustard lear can have a recovery function, which was not via ethanol metabolism on the symptoms of alcohol related diseases.(Korean J Human Ecology 1(1) : 94~102, 1998)

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Enhancement of Paper Characteristics by Polyvinyl Alcohol/Polyamide-epichlorohydrin Coating as a Complex Strength Additive (Polyvinyl Alcohol/Polyamide-epichlorohydrin 복합 지력증강제에 의한 종이 특성 향상)

  • Jang, Yunjae;Lee, Hwaljong;Kang, Ho-Jong
    • Polymer(Korea)
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    • v.38 no.5
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    • pp.620-625
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    • 2014
  • The effect of polyvinyl alcohol/polyamide-epichlorohydrin (PVA/PAE) complex strengthening additive on dry and wet strength and surface properties of paper was investigated. The enhancements of dry and wet strength and dimensional stability were found when PVA/PAE was applied as a complex strengthening additive compared with the cases of applying individual PVA or PAE. This was understood as physical crosslinking between PVA and PAE in the PVA/PAE complex strength additive. This complex strengthening additive also lowered surface roughness and increased sizing. As a result, PVA/PAE complex strengthening additive provided the distinctive gain dot in printed papers.