• Asian-Australasian Journal of Animal Sciences
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• 제19권4호
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• pp.459-462
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• 2006

Prolactin (PRL) plays an important role in promoting mammalian mammary gland development, and milk production during lactation. Therefore the PRL gene was chosen as a candidate gene for milk traits in Holstein dairy cows. PCR-SSCP and PCR-RFLP were used to analyze genetic variations in the 5' regulation region of the PRL gene. In this part of the gene, two new polymorphic sites were detected in the Chinese Holstein dairy cows. One was a XbaI-RFLP locus, and the other was an SSCP locus. Statistical analysis showed that the XbaI-RFLP locus and the SSCP locus had a significant positive effect on milk traits.

• Journal of Power Electronics
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• 제14권2호
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• pp.282-291
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• 2014

This paper presents a detailed theoretical analysis and performance assessment of the capacitor voltage balancing strategies for staircase modulated modular multilevel converters (MMC) in terms of the algorithm structures, voltage balancing effect, and switching frequency. A constant-frequency redundancy selection (CFRS) method with minimal switching loss is proposed and the function realization of specific modules of the algorithm is given. This method is simple and efficient in both switching frequency and regulation capacity. Laboratory results show very good agreement with the theoretical analysis and numerical simulations.

• 대한인간공학회지
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• 제34권3호
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• pp.265-278
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• 2015

Objective:To study the sources of indoor noise, its effects on human health, noise assessment and regulation through the use of standards, and techniques used to reduce noise. Background: Noise significantly affects the living environment, and there are an increasing number of reports of its impacts on human health. Method: We reviewed domestic and foreign data regarding environmental noise, and examined its effects and the standards used to regulate noise levels. Results: We describe the major sources of indoor noise and suggest possible legal standards, as well as recommended criteria for the control of noise. Conclusion: South Korea has higher legal standards of environmental noise than international standards in terms of threshold values. People in Korea are exposed to various sources of noise, and therefore the reduction of noise is urgently required. Application: Depending on the features of indoor spaces, an appropriate degree of indoor noise can be determined and techniques to reduce excess noise are required.

• 인터넷정보학회논문지
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• 제12권4호
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• pp.51-59
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• 2011

본 연구의 목적은 해외유료방송의 시장집중과 시장성과 간의 실증적인 관계분석을 통해 국내 미디어산업의 바람직한 규제 및 정책 방향을 고찰해 보는 것이다. 세계적으로 방송통신이 융합되어 규제가 완화되고 있음에도 불구하고, 국내의 경우에는 미디어 시장이 특정사업자에 집중될 경우 시장 비효율이 발생하고 다양성이 훼손된다는 전제 하에, 여전히 시장집중현상을 집중적으로 규제하고 있다. 본 연구에서는 전 세계 17개 유료방송시장을 대상으로 1위 사업자의 시장점유 정도가 시장가격과 서비스 보급에 영향을 미치는지 분석하였다. 조사결과 시장집중 현상이 초래되어도 가격이 상향되거나 서비스 보급이 지연되는 않는 것으로 분석되었다. 본 연구결과, 시장성과에 영향을 주는 요인들이 다각화되었기 때문에 단순히 시장집중만을 규제하면 기술혁신 침체와 같은 부작용도 발생하는 것을 포함하여 다양한 시사점들이 도출되었다.

• 한국컴퓨터정보학회논문지
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• 제22권4호
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• pp.123-130
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• 2017

This study investigates the variables associated with the conspicuous consumption patterns of children consumers. The empirical analysis was done on materialism, recognition of advertising, self-regulation ability, and impulsive consumption. The results were as follows. First of all, children consumers tend to a little higher self-directed conspicuous consumption than others-oriented conspicuous consumption. Second, as a result of analyzing conspicuous consumption according to social demographic characteristics, a high tendency of conspicuous consumption was shown in groups that think their household economic status is upper middle class. Third, the variables affecting conspicuous consumption patterns of children consumers were materialism, recognition of advertising, and impulsive consumption. Materialism, recognition of advertising, and impulsive consumption had a positive effect.

• 미생물학회지
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• 제25권3호
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• pp.189-197
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• 1987

배지성분으로 첨가된 glutamate의 농도가 균의성장고 tylosin 생합성에 미치는 영향을 조사하였다. 그 결과 oxaloacetate를 공동기질로 사용하는 효소의 활성에 의하여 균의 성장과 tylosin의 생합성이 조절됨을 알았다. 즉, citrate synthase와 aspartate aminotransferase의 활성은 균의 성장에 아주 긴요하며 methylmalonyl-CoA carboxytransferase의 활성은 tylosin 생합성에 아주 중요한 효소임을 알았다. Glutamate의 농도는 우의 효소의 활성에 직접적으로 영향을 주고 있음을 알았다.

• International Journal of Industrial Entomology and Biomaterials
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• 제47권2호
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• pp.134-139
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• 2023

SIRT5 and PRDx1 play crucial roles in cancer and are involved in the basic mechanisms of reactive oxygen species detoxification. In our previous studies, we showed that hemolymph extracts of immune-challenged Bombyx mori have antioxidant properties. Following H₂O₂ stimulation, immune-challenged B. mori hemolymph extracts elicited SIRT5 downregulation activity, reaching effective activity at the highest concentration of 100 ppm. Additionally, cells treated with immune-challenged B. mori hemolymph extracts demonstrated increased PRDx1 mRNA expression compared to that of PBS-treated cells. Therefore, immune-challenged B. mori hemolymph extracts offer a potential auxiliary means of treating drug-resistant tumors through downregulation of SIRT5 and upregulation of PRDx1 expression. Nevertheless, further studies on the effects of B. mori hemolymph on SIRT5 and PRDx1 regulation are pertinent for using it as a food or pharmaceutical material and understanding its therapeutic effect on tumors, including those that are drug-resistant.

• The Korean Journal of Physiology and Pharmacology
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• 제7권3호
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• pp.181-185
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• 2003

Whether there exists a sympathetic neural regulation on the aquaporin (AQP) channels in the kidney was examined. Male Sprague-Dawley rats were used. They were renal nerve denervated by stripping the nervous and connective tissues passing along the renal artery and vein, and painting these vessels with 10% phenol solution through a midline abdominal incision. Three days later, the expression of AQP1-4 proteins in the denervated kidneys was determined. The content of norepinephrine was found significantly decreased following the denervation. Accordingly, the expression of AQP2 proteins was markedly decreased. The expression of AQP3 and AQP4 was also slightly but significantly decreased, while that of AQP1 was not. Neither the basal nor the AVP-stimulated accumulation of cAMP was significantly affected in the denervated kidney. It is suggested that the sympathetic nervous system has a tonic stimulatory effect on AQP channels in the kidney.

• Biomolecules & Therapeutics
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• 제32권5호
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• pp.540-545
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• 2024

In this study, the potential effects of pyronaridine, an antimalarial agent, on airway MUC5AC mucin gene expression were investigated. The human pulmonary epithelial NCI-H292 cells were pretreated with pyronaridine for 30 min and then stimulated with phorbol 12-myristate 13-acetate (PMA) for 24 h. The effect of pyronaridine on the PMA-induced nuclear factor kappa B (NF-κB) signaling pathway was also examined. Pyronaridine inhibited glycoprotein production and mRNA expression of MUC5AC mucins induced by PMA through the inhibition of degradation of inhibitory kappa Bα and NF-κB p65 nuclear translocation. These results suggest that pyronaridine suppresses gene expression of mucin through regulation of the NF-κB signaling pathway in human pulmonary epithelial cells.

• Asian-Australasian Journal of Animal Sciences
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• 제23권12호
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• pp.1668-1676
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• 2010

The somatotropic axis plays a key role in proliferation and differentiation of avian organs during both pre- and posthatching periods. This review discusses the complexity of regulation of the endocrine system for chicken development and growth by growth hormone (GH), insulin-like growth factor (IGF), and IGF binding protein (IGFBP). In addition, the thyrotropic axis, including thyrotropin-releasing hormone (TRH) and thyroid hormones ($T_4$ and $T_3$), is also involved in the GH-secreting pattern. In mammals, IGFI and -II are always sequestered in a 150 kDa non-covalent ternary complex. This complex consists of one molecule each of IGF-I or IGF-II, IGFBP-3 or IGFBP-5 and an acid labile subunit (ALS). Chick ALS is identified in different strains for the first time, and further investigation of the expression of ALS on developmental stage and ALS effect on IGF bioavailability may be addressed in the future.