• 제목/요약/키워드: Effect Analysis of Risk Factors

검색결과 740건 처리시간 0.031초

근로자의 화학적 노출과 주관적 호흡곤란 증상간의 연관성: 3차 근로환경조사 자료 분석 (Association of Exposure to Chemicals with Dyspnea among Employed Workers: Analysis of the 3rd Korean Working Conditions Survey)

  • 박문영;황성호;홍기명;오세은;이경무
    • 한국산업보건학회지
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    • 제26권1호
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    • pp.64-74
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    • 2016
  • Objectives: The purpose of this study was to investigate whether chemical exposure among workers has relevance to dyspnea using data from the $3^{rd}$ Korea Working Conditions Survey. Methods: The research subjects were 29,711 wage workers. Chemical exposures consist of four factors, (1) breathing in vapors, fumes, dust and dirt, (2) breathing in organic solvent vapors, (3) handling or touching chemicals, and (4) secondhand smoke. Multiple logistic regression analysis was performed to examine the association between chemical exposure and dyspnea in the last 12months using proc surveylogistic in SAS 9.3 statistical software excluding people who had received a diagnosis of hypertension or obesity that can affect the respiratory distress symptoms(n=27,842). Results: Chemical exposure among workers was associated with dyspnea after adjustment for demographics and job characteristics. Prevalence of dyspnea was 4.9 per 1,000 among men and 5.8 per 1,000. Compared to a total score of 0 points of chemical exposure among workers, a total score of 1, 2-3, and 4 points tended to have increased risk of dyspnea in a dose-response manner for both men (OR=1.43, 1.93, and 4.26; P-for trend=0.002) and women(OR=1.10, 2.81, and 7.70; P-for trend=0.002). Stratified analysis by duration of current job showed that the association between chemical exposure and dyspnea tended to get stronger until 15 years and then disappeared afterwards, which reflects healthy worker survivor effect. Conclusions: We observed significant association between chemical exposure and dyspnea using the data of the $3^{rd}$ Korea Working Conditions Survey. Our results warrants providing knowledge related to chemical exposure, performing prevention activities, and creating various health policies to protect workers.

연약 점성토 지반에 시공되는 원형 수직구의 히빙 안정성에 대한 수치해석적 연구 (Numerical study on basal heave stability of a circular vertical shaft constructed in clay)

  • 강석준;조계춘
    • 한국터널지하공간학회 논문집
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    • 제24권3호
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    • pp.231-245
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    • 2022
  • 지반강도가 낮은 연약 점성토 지반을 대상으로 수직구가 시공되는 경우, 굴착면에서의 토압 불균형에 대한 지반의 지지력이 낮아 굴착면이 융기하는 히빙이 발생할 위험이 존재한다. 히빙에 대한 안정성을 평가하기 위해 안전율을 계산하는 방법들이 제안되어왔으나, 이론적인 유도 과정에서 많은 가정사항들이 포함되어 정확한 히빙 안정성 평가가 어렵다는 한계를 가진다. 본 연구에서는 선행 연구를 보완하기 위해 원형 수직구가 연약 점성토 지반에 시공되는 경우를 상정하여 굴착 형상에 따른 지반 지지력의 변화, 지반 점성토의 비균질성, 그리고 관내토의 효과에 대한 이론적 접근을 통해 기존 안전율 제안식을 보완하였다. 보완된 식의 검증과 다양한 사례 연구를 통한 히빙 안정성 검토를 위해 원형 수직구 굴착 시 발생하는 굴착면의 히빙을 3차원 수치해석으로 모사하여 안전율을 도출하였다. 수치해석 및 히빙 안전율 제안식들을 이용하여 다양한 인자의 변화에 따른 히빙 안전율의 변화를 검토한 결과, 본 연구에서 추가적으로 보완된 특성이 3차원 안전율 식 내에 적절하게 반영되었음을 확인하였다. 다양한 사례를 모사하여 수행된 수치해석 결과를 이용하여 수식을 구성하는 인자들이 히빙 안전율에 미치는 영향을 도출하였으며, 깊이에 따른 비배수 전단강도 증가의 고려 여부가 안전율 값 산정에 지배적인 영향을 미치는 것을 확인하였다.

창업가 특성요인과 창업코칭활동이 창업성과에 미치는 영향: 의식전환을 매개로 (Impact Analysis of Coaching Activities over Entrepreneur with respect to Entrepreneurs' Personal Characteristics on the Performance of Startups: Focusing on Entrepreneurs's Awareness Conversion Effect)

  • 전은지;양영석;김명숙
    • 벤처창업연구
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    • 제14권1호
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    • pp.47-58
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    • 2019
  • 본 연구는 창업가 개인특성과 환경특성이 창업코칭활동과 창업가 의식전환을 매개로 창업성과에 미치는 영향에 관한 연구이다. 특히 본 논문은 여러 사업실패원인이 있지만, 대다수의 창업가들이 유연하지 못한 사고로 인하여 성공적인 창업을 하지 못하고 좌절하는 것이 큰 문제로 제기되고 있는 상황에서 이 위험을 줄이기 위해 사업 및 시장경험자와 코칭을 통한 협력적 사업실행이 요구됨을 문제제기로 작성되었다. 이에 본 논문은 선행연구를 창업코칭 중심으로 진행하였는데, 이는 멘토링이 창업가의 문제점을 해결함에 있어 멘토의 직접적인 의견을 제시하는 방식으로 진행되어, 창업가가 스스로 문제를 인식하고 해결하는 행동지향적인 과정이 미흡하기 때문이다. 그렇기에 창업가의 근본적인 문제 해결을 위해 창업코칭활동을 통하여 창업가 스스로 본인의 문제점을 인식하고 답을 찾도록 하는 코칭의 중요성이 강조되고 있다. 본 연구는 크게 네 가지 연구를 진행하였다. 첫째, 창업가의 개인특성이 창업코칭활동에 영향을 미치는지 여부 분석, 둘째, 창업가의 환경 특성이 창업코칭활동에 영향을 미치는지 여부, 셋째, 창업코칭활동이 창업가의 의식전환에 영향을 미치는지 여부, 넷째, 이러한 창업가의 의식전환이 창업성과에 미치는 영향분석 등이다. 실증분석의 결과, 본 연구는 창업가 개인특성이 창업코칭활동에 유의미한 영향을 미치지 못하였지만, 창업가 환경특성은 창업코칭활동에 정(+)의 영향을 미치는 것으로 확인되었다. 더불어 창업코칭활동은 창업가의 의식전환에 정(+)의 영향을 미쳤으며, 창업가 의식전환은 창업성과에 정(+)의 영향을 미침을 확인하였다. 이로써 본 연구는 창업코칭활동과 창업가 의식전환이 창업성과에 긍정적인 영향을 주는 것으로 확인할 수 있었다. 본 연구의 결론은 창업코칭활동으로 창업가의 의식이 전환되어, 창업성과를 높이기 위한 목표 재설정과 실행계획 수립에 도움을 주는 것으로 나타났다. 이에 본 연구결과는 창업기업을 대상으로 하는 다양한 실전창업교육 프로그램들에 코칭방식의 진행이 적극 수용되어야 함을 시사점으로 제시하고 있다.

IoT 제품에 관한 소비자의 감성적 소비가치와 구매의도에 관한 연구 - EEG를 활용한 선호도 연구를 중심으로 - (A Study on Consumer's Emotional Consumption Value and Purchase Intention about IoT Products - Focused on the preference of using EEG -)

  • 이영애;김승인
    • 커뮤니케이션디자인학연구
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    • 제68권
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    • pp.278-288
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    • 2019
  • 광범위하고 다양하게 발전해가고 있는 IoT 시장에서 리스크와 사용 편리성이 구매 의도에 미치는 영향분석과 이에 대한 감성적 소비 가치의 조절 효과를 분석하고자 하였다. 본 연구에서는 크게 세 가지 제품군에서 각각 2가지의 제품을 선정해 연구를 시행하였다. 연구의 방법으로는 크게 세 가지로 첫째, 이론적 고찰, 둘째, 연구모형 검증을 위해 IoT 제품의 소비가 가능한 20대 이상의 남녀 250명을 대상으로 survey 분석을 하였으며 분석은 SPSS를 이용하여 기술통계로 신뢰도 분석과 요인분석을 하였다. 셋째, Survey 분석의 오류를 해소하기 위해 남녀 20~30대 8명을 대상으로 심층 인터뷰와 간접적 체험에 따른 뇌전도(EEG)의 변화를 측정하였다. 본 연구의 가설의 실증분석 결과 IoT 제품의 사용 편리성이 구매 의도에 있어서 영향을 미치는 것을 확인할 수 있었다. 리스크가 구매 의도에 부정적인 영향을 보일 것으로 예측하였으나 본 연구에서는 유의미하지 않게 나타났다. 이는 일반적으로 고객이 하이테크제품을 구매할 때 제품구매 비용, 사용 비용, 처분에 관한 비용 등 금전적 손실에 대해서 일반제품의 경우보다 경시되는 경향을 나타낸 것이 아닌가 짐작하였고, 심층 인터뷰와 EEG 분석결과 IoT 제품의 특성상 리스크가 있어도 신기술의 신기한 제품, 나의 삶을 이롭게 할 것이라는 막연한 생각 등으로 구매해보고 사용해보고자 하는 욕구가 있다고 이야기했다. 감성적 소비가치의 하위요소인 심미성, 상징성, 쾌락성 모두 큰 영향을 미치는 것으로 확인되었다. 이는 감성적 소비가치가 구매 의도에 긍정적인 영향을 주는 것으로 나타난 선행연구들과 일치하는 결과이다. 심층 인터뷰와 EEG 분석결과 역시 동일한 결과를 얻을 수 있었다. 본 연구를 통해 감성적 소비가치가 IoT 제품 구매 의도에 영향을 미치는 것을 밝혀냈다. 이는, IoT 제품을 생산하는 기업들은 좀 더 감성적 소비가치를 적용한 마케팅에 집중해야 할 필요성으로 보인다.

산업보건연구에서의 통계학적 분석 (Statistical analyses in an occupational health study)

  • 백도명;최정근;손미아
    • 응용통계연구
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    • 제6권2호
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    • pp.201-215
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    • 1993
  • 산업보건연구의 통계학적 분석은 작업환경측정에 대한 평가방법과 산업보건에 특유한 혼란 변수의 통제 등 건강상태와의 연관성을 분석하는 평가방법에 있어 다른 보건통계분야와 구 별되는 특성을 지니고 있다. 본 논문에서는 주물공장 근로자들의 호흡기 건강상태와 작업환 경에서 폭로되는 유해물질에 대한 조사를 통하여 산업보건연구에 사용되는 통계학적 분석에 대한 기술을 하였다. 조사된 환경측정결과의 일부는 허용폭로기준을 초과하고 있었는 바, 폭 로기준의 준수여부를 판정하기 위하여 작업환경측정결과와 그들의 대수변환치들로부터 얻은 산술평균과 대수평균들이 폭로기준과 다른지에 대한 t-검정을 실시하였다. 환경측정을 비롯 한 위험요인들과 그들로 인한 건강상태와의 관계 분석을 위해, 범주적 건강측정 변수인 경 우에는 $\chi$-square 검정과 다변량 logistic분석을 시행하였고, 연속적 변수인 경우에는 다 변량 회귀분석을 시행하였다. 작업환경내의 오염물질의 농도는 그 측정장소와 측정시점에 따라 매우 가변적이다. 이러한 작업환경의 측정결과를 평가하는데 있어 사용될 수 있는 서 로 다른 여러 지수들의 장단점과 가변적 측정결과들로 인한 오차를 보정할 수 있는 통계학 적 분석방법에 대한 논의를 하였다. 본 조사의 폐기능검사 결과는 직업에서 폭로되는 정도 와 아무 연관성을 보이고 있지 않은 바, 이는 “건강한 그로자 효과”에 기인한 것으로 추정되고 있다.

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스마트폰 위치기반 어플리케이션의 이용의도에 영향을 미치는 요인: 프라이버시 계산 모형의 적용 (Factors Influencing the Adoption of Location-Based Smartphone Applications: An Application of the Privacy Calculus Model)

  • 차훈상
    • Asia pacific journal of information systems
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    • 제22권4호
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    • pp.7-29
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    • 2012
  • Smartphone and its applications (i.e. apps) are increasingly penetrating consumer markets. According to a recent report from Korea Communications Commission, nearly 50% of mobile subscribers in South Korea are smartphone users that accounts for over 25 million people. In particular, the importance of smartphone has risen as a geospatially-aware device that provides various location-based services (LBS) equipped with GPS capability. The popular LBS include map and navigation, traffic and transportation updates, shopping and coupon services, and location-sensitive social network services. Overall, the emerging location-based smartphone apps (LBA) offer significant value by providing greater connectivity, personalization, and information and entertainment in a location-specific context. Conversely, the rapid growth of LBA and their benefits have been accompanied by concerns over the collection and dissemination of individual users' personal information through ongoing tracking of their location, identity, preferences, and social behaviors. The majority of LBA users tend to agree and consent to the LBA provider's terms and privacy policy on use of location data to get the immediate services. This tendency further increases the potential risks of unprotected exposure of personal information and serious invasion and breaches of individual privacy. To address the complex issues surrounding LBA particularly from the user's behavioral perspective, this study applied the privacy calculus model (PCM) to explore the factors that influence the adoption of LBA. According to PCM, consumers are engaged in a dynamic adjustment process in which privacy risks are weighted against benefits of information disclosure. Consistent with the principal notion of PCM, we investigated how individual users make a risk-benefit assessment under which personalized service and locatability act as benefit-side factors and information privacy risks act as a risk-side factor accompanying LBA adoption. In addition, we consider the moderating role of trust on the service providers in the prohibiting effects of privacy risks on user intention to adopt LBA. Further we include perceived ease of use and usefulness as additional constructs to examine whether the technology acceptance model (TAM) can be applied in the context of LBA adoption. The research model with ten (10) hypotheses was tested using data gathered from 98 respondents through a quasi-experimental survey method. During the survey, each participant was asked to navigate the website where the experimental simulation of a LBA allows the participant to purchase time-and-location sensitive discounted tickets for nearby stores. Structural equations modeling using partial least square validated the instrument and the proposed model. The results showed that six (6) out of ten (10) hypotheses were supported. On the subject of the core PCM, H2 (locatability ${\rightarrow}$ intention to use LBA) and H3 (privacy risks ${\rightarrow}$ intention to use LBA) were supported, while H1 (personalization ${\rightarrow}$ intention to use LBA) was not supported. Further, we could not any interaction effects (personalization X privacy risks, H4 & locatability X privacy risks, H5) on the intention to use LBA. In terms of privacy risks and trust, as mentioned above we found the significant negative influence from privacy risks on intention to use (H3), but positive influence from trust, which supported H6 (trust ${\rightarrow}$ intention to use LBA). The moderating effect of trust on the negative relationship between privacy risks and intention to use LBA was tested and confirmed by supporting H7 (privacy risks X trust ${\rightarrow}$ intention to use LBA). The two hypotheses regarding to the TAM, including H8 (perceived ease of use ${\rightarrow}$ perceived usefulness) and H9 (perceived ease of use ${\rightarrow}$ intention to use LBA) were supported; however, H10 (perceived effectiveness ${\rightarrow}$ intention to use LBA) was not supported. Results of this study offer the following key findings and implications. First the application of PCM was found to be a good analysis framework in the context of LBA adoption. Many of the hypotheses in the model were confirmed and the high value of $R^2$ (i.,e., 51%) indicated a good fit of the model. In particular, locatability and privacy risks are found to be the appropriate PCM-based antecedent variables. Second, the existence of moderating effect of trust on service provider suggests that the same marginal change in the level of privacy risks may differentially influence the intention to use LBA. That is, while the privacy risks increasingly become important social issues and will negatively influence the intention to use LBA, it is critical for LBA providers to build consumer trust and confidence to successfully mitigate this negative impact. Lastly, we could not find sufficient evidence that the intention to use LBA is influenced by perceived usefulness, which has been very well supported in most previous TAM research. This may suggest that more future research should examine the validity of applying TAM and further extend or modify it in the context of LBA or other similar smartphone apps.

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Estimation of Survival Rates in Patients with Lung Cancer in West Azerbaijan, the Northwest of Iran

  • Abazari, Malek;Gholamnejad, Mahdia;Roshanaei, Ghodratollah;Abazari, Reza;Roosta, Yousef;Mahjub, Hossein
    • Asian Pacific Journal of Cancer Prevention
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    • 제16권9호
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    • pp.3923-3926
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    • 2015
  • Background: Lung cancer is a fatal malignancy with high mortality and short survival time. The aim of this study was to estimate survival rates of Iranian patients with lung cancer and its associate predictive factors. Materials and Methods: The study was conducted on 355 patients admitted to hospitals of West Azerbaijan in the year 2007. The patients were followed up by phone calls until the end of June 2014. The survival rate was estimated using the Kaplan-Meier method and log-rank test for comparison. The Cox's proportional hazard model was used to investigate the effect of various variables on patient survival time, including age, sex, Eastern Cooperative Oncology Group (ECOG) performance, smoking status, tumor type, tumor stage, treatment, metastasis, and blood hemoglobin concentration. Results: Of the 355 patients under study, 240 died and 115 were censored. The mean and median survival time of patients was 13 and 4.8 months, respectively. According to the results of Kaplan-Meier method, 1, 2, and 3 years survival rates were 39%, 18%, and 0.07%, respectively. Based on Cox regression analysis, the risk of death was associated with ECOG group V (1.83, 95% CI: 1 Conclusions: The survival time of the patients with lung cancer is very short. While early diagnosis may improve the life expectancy effective treatment is not available.

Anti-Oxidative Effect of Myrtenal in Prevention and Treatment of Colon Cancer Induced by 1, 2-Dimethyl Hydrazine (DMH) in Experimental Animals

  • Lokeshkumar, Booupathy;Sathishkumar, Venkatachalam;Nandakumar, Natarajan;Rengarajan, Thamaraiselvan;Madankumar, Arumugam;Balasubramanian, Maruthaiveeran Periyasamy
    • Biomolecules & Therapeutics
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    • 제23권5호
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    • pp.471-478
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    • 2015
  • Colon cancer is considered as the precarious forms of cancer in many developed countries, with few to no symptoms; the tumor is often diagnosed in the later stages of cancer. Monoterpenes are a major part of plant essential oils found largely in fruits, vegetables and herbs. The cellular and molecular activities show therapeutic progression that may reduce the risk of developing cancer by modulating the factors responsible for colon carcinogenesis. Colon cancer was induced with DMH with a dose of (20 mg/Kg/body weight) for 15 weeks by subcutaneous injection once in a week. Myrtenal treatment was started with (230 mg/Kg/body weight) by intragastric administration, one week prior to DMH induction and continued till the experimental period of 30 weeks. The Invivo results exhibit the elevated antioxidant and lipid peroxidation levels in DMH treated animals. The Histopathological analysis of colon tissues well supported the biochemical alterations and inevitably proves the protective role of Myrtenal. Treatment with myrtenal to cancer bearing animals resulted in a remarkable increase in the inherent antioxidants and excellent modulation in the morphological and physiological nature of the colon tissue. It is thus concluded that myrtenal exhibits excellent free radical scavenging activity and anticancer activity through the suppression of colon carcinoma in Wistar albino rats.

Effect of Streptozotocin-Induced Diabetes on Bone and Heart Development in Juvenile Rats

  • Kim, Joo-Heon;Lee, Young-Jeon;Lee, Sang-Un;Suzuki, Takao;Lee, Sang-Kil;Kang, Tae-Young;Hong, Yong-Geun
    • Reproductive and Developmental Biology
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    • 제34권2호
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    • pp.81-88
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    • 2010
  • Our objective of current study was to investigate the development of bone and heart in association with diabetes mellitus (DM). DM was induced by administering an intraperitoneal injection of streptozotocin (STZ; 60 mg/kg) to 4-week-old Sprague-Dawley rats. Body weight and blood glucose were monitored, and rats were sacrificed after 2 or 5 weeks. The left ventricle (LV), including the interventricular septum, was weighed, and body weight and tibial bone length were assessed. Young diabetic rats showed reduced growth in terms of tibial length and body weight compared to controls. Moreover, diabetic males showed more significant growth suppression and reduced LV size than diabetic females. Morphometric analysis of tibiae from diabetic rats revealed suppressed bone growth at 2 and 5 weeks, with no difference between genders. STZ-induced diabetes decreased bone growth and retarded pre-pubertal heart development. As a result, diabetes may increase cardiovascular risk factors and lead to eventual heart failure. Therefore, new therapeutic approaches are required for diabetic children exhibiting growth retardation. Heart growth factor, exercise, and cardiopulmonary physical therapy may be required to promote heart development and physiological function.

Effects of Antioxidant Tempol on Systematic Inflammation and Endothelial Apoptosis in Emphysematous Rats Exposed to Intermittent Hypoxia

  • Zhao, Haiyan;Zhao, Yaping;Li, Xin;Xu, Leiqian;Jiang, Fangxin;Hou, Wanju;Dong, Lixia;Cao, Jie
    • Yonsei Medical Journal
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    • 제59권9호
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    • pp.1079-1087
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    • 2018
  • Purpose: Obstructive sleep apnea and chronic obstructive pulmonary disease are independent risk factors of cardiovascular disease (CVD), and their coexistence is known as overlap syndrome (OS). Endothelial dysfunction is the initial stage of CVD; however, underlying mechanisms linking OS and CVD are not well understood. The aim of this study was to explore whether OS can lead to more severe inflammation and endothelial apoptosis by promoting endothelial dysfunction, and to assess the intervention effects of antioxidant tempol. Materials and Methods: Male Wistar rats (n=66) were exposed to normal oxygen [normal control (NC) group], intermittent hypoxia (IH group), cigarette smoke (CH group), as well as cigarette smoke and IH (OS group). Tempol intervention was assessed in OS group treated with tempol (OST group) or NaCl (OSN group). After an 8-week challenge, lung tissues, serum, and fresh blood were harvested for analysis of endothelial markers and apoptosis. Results: The levels of intracellular adhesion molecule-1, vascular cellular adhesion molecule-1, and apoptosis in circulating epithelial cells were the highest in OS group and the lowest in NC group. These levels were all greater in IH group than in CH group, and were lower in OST group than in OS and OSN groups (all p<0.001). Conclusion: Synergistic effects of IH with cigarette smoke-induced emphysema produce a greater inflammatory status and endothelial apoptosis. OS-related inflammation and endothelial cell apoptosis may play important roles in promoting cardiovascular dysfunction, and antioxidant tempol could achieve a partial protective effect.