• Journal of Embryo Transfer
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• v.30 no.3
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• pp.229-237
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• 2015

To improve the developmental potential of bovine somatic cell nuclear transfer (SCNT) embryos, this study compared the developmental rates to blastocyst stage in the SCNT embryos using donor fibroblasts treated with 5-azacytidine (5AC) and S-adenosylhomocysteine (SAH) at different concentrations. Their reprogramming efficiency level was investigated with level of telomerase activity. Donor fibroblasts isolated from adult ear skin of a cow were exposed to 5AC and SAH at different concentrations during 2 passages. After nuclear transfer into enucleated recipient oocytes, the cleavage and developmental rates were significantly (p<0.05) decreased in the SCNT embryos using 5AC-treated fibroblasts (5AC-SCNT embryos), compared with those of non-treated control (control-SCNT embryos) and SAH-treated fibroblasts (SAH-SCNT embryos). The developmental rates to blastocyst stage tended to be slightly increased in the SAH-SCNT embryos at each of the concentrations, and especially, the developmental rates in the SCNT embryos using 1.0 mM SAH-treated fibroblasts were significantly (p<0.05) higher than that of control SCNT embryos. The mean numbers of total and ICM cell in blastocysts were also significantly (p<0.05) decreased in the 5AC-SCNT embryos, compared with those of other SCNT blastocysts. Further, the level of telomerase activity was also significantly (p<0.05) decreased in the 5AC-SCNT embryos than those of control and SAH-SCNT embryos. Whereas, a significantly (p<0.05) up-regulated telomerase activity was observed in SAH-SCNT embryos, compare with that of control-SCNT embryos. In conclusion, SCNT embryos using hypomethylated donor cells with SAH, not 5AC, may improve the developmental potential and reprogramming efficiency.

• Korean Journal of Applied Biomechanics
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• v.24 no.2
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• pp.121-129
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• 2014

The purpose of this study was to investigate the effect of the toe headings on the biomechanics of knee joint in drop landing in an attempt to find the potential risk of non-contact anterior cruciate ligament (ACL) injury. Seventeen male college students ($20.5{\pm}1.1$ yrs; $175.2{\pm}6.4$ cm; $68.8{\pm}5.8$ kg), having no neuromuscular injury within an year, participated in this study. Three different toe headings such as toe-in (TI), neutral (N), and toe-out (TO) positions were tested. Motion capturing system consisting of eight high speed cameras and two force platforms were used to collect three-dimensional motion data and ground reaction force data during landing. Results indicated joint angles and peak joint moments were significantly affected by the toe headings. TI position produced larger valgus angle due to reduce knee distance in addition to higher flexion and valgus moment than other positions, which was somewhat vulnerable to the potential risk of non-contact ACL injury. TO position caused the largest internal rotation angle with smaller joint moments. Therefore, it is recommended that athletes need to land on the ground with neutral toe-heading position as possible in order to minimize the potential risk of non-contact ACL injury.

• The Journal of the Korean dental association
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• v.55 no.4
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• pp.284-294
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• 2017

Recently, education is regarded as a service item and university education services are being exported abroad. In the form of educational export operations, export of educational contents and curriculum, specific consultancy projects for foreign institutes, installation of local educational facilities, or attracting foreign students are being carried out. Korea has the potential and competitiveness to export dental education. The advantages of Korea's dental education services, such as dental equipment and materials, excellent education programs, and high-quality human resources, will enable the export of education services in various ways. Establishment of educational infrastructure and educational programs for overseas dental students, export of educational consulting items, clinical training programs for foreign dentists abroad, invitation for international clinical workshops, dispatch of faculty members, exchange student programs can be considered as exporting dental education service items. Therefore, in a long-term perspective, it is necessary to establish differential and appropriate educational export plans.

• Journal of Korean Elementary Science Education
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• v.22 no.2
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• pp.211-222
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• 2003

Science has developed along with human society and history. In today's society ruled by pluralism, an educational approach using the historical materials which represent their own cultures will make science education more effective. The purpose of this study was to search for the meaning of science education related with a history of science, and to suggest the possibility for science education based on Korean history of science. The conclusions of this study is below: (1) The history of science is useful to teaching science in K-12 setting. That is because it was helpful to make a scientific concept and to invite student's interest about learning science. Moreover, it was most suitable to teach the nature of science as well as the relation between science and society. (2) A model which consists of 15 types of science education materials using Korean history was suggested. This model plays a potential role as a R&D framework of developing teaching & learning materials based on the history of Korean Science.

• Journal of Information Processing Systems
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• v.17 no.5
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• pp.960-971
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• 2021

As the era of the 4th Industrial Revolution enters, the importance of software safety is increasing, but related systematic educational curriculum and trained professional engineers are insufficient. The purpose of this research is to propose the high priority elements for the software safety education program through needs analysis. For this purpose, 74 candidate elements of software safety education program were derived through contents analysis of literature and nominal group technique (NGT) process with five software safety professionals from various industries in South Korea. Targeting potential education participants including industrial workers and students, an on-line survey was conducted to measure the current and required level of each element. Using descriptive statistics, t-test, Borich needs assessment and Locus for focus model, 16 high priority elements were derived for software safety education program. Based on the results, suggestions were made to develop a more effective education program for software safety education.

• The Mathematical Education
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• v.63 no.2
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• pp.387-392
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• 2024

The use of artificial intelligence (AI) in mathematics education has advanced as a means for promoting understanding of mathematical concepts, academic achievement, computational thinking, and problem-solving. From a total of 13 studies in this special issue, this editorial reveals threads of potential and future directions to advance mathematics education with the integration of AI. We generated five themes as follows: (1) using ChatGPT for learning mathematical content, (2) automated grading systems, (3) statistical literacy and computational thinking, (4) integration of AI and digital technology into mathematics lessons and resources, and (5) teachers' perceptions of AI education. These themes elaborate on the benefits and opportunities of integrating AI in teaching and learning mathematics. In addition, the themes suggest practical implementations of AI for developing students' computational thinking and teachers' expertise.

• Journal of the Korean Chemical Society
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• v.46 no.4
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• pp.363-377
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• 2002

The purpose of this study was to improve the problems of the voltaic cell described in the science textbooks of secondary schools. For this purpose, the contents of science textbooks which are related to the voltaic cell were analyzed and the problems which were not explained clearly by theorems were tried to be explained by experiments, and lastly sug-gestions were made toward the improvements regarding the voltaic cell in the science textbooks. The findings are that there are problems on the ways of ensuring whether the voltaic cell operates properly as a chemical battery, on the explanation of why the hydrogen bubbles form at the zinc electrode, on the cell potential, on the unification of the electrode terminology used, and on the mention of the current. Solutions to the problems except the cell potential were suggested. According to the experiment, the theoretical potential was calculated by considering the potentials of redox reactions at the two electrodes of the cell and by taking into account the characteristics of the electrodes such as the work function, ionization energy, stan-dard reduction potential, and electronegativity.The cell potential of the voltaic cell is explained by several factors. In the improved version of the textbook's introduction section to the voltaic cell, it is necessary to describe the voltaic cell his-torically.For the conceptual section, it should be explained in terms of the Daniel cell.

• Asia-Pacific Journal of Business Venturing and Entrepreneurship
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• v.16 no.2
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• pp.123-141
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• 2021

This research examined the relationship between entrepreneurial attitude and entrepreneurial opportunity recognition and university students' entrepreneurial potential in the entrepreneurship of university students. Accordingly, this research confirmed the significant influence between the awareness formation of entrepreneurial opportunities and the attitude toward entrepreneurial, which affect the improvement of the entrepreneurial potential of university students, and analyzed the influence relationship between the variables according to the start-up education and the role model. The results of the study are summarized as follows. First, creativity, leadership, and individual control have a significant effect on information search. Insight and achievement have no statistically significant effect on information search. Second, creativity, leadership, and insight were found to have a significant effect on the information combination, and the sense of achievement and individual control did not significantly affect the information combination statistically. Third, creativity, leadership, and individual control have a significant effect on opportunity capture. Insight and achievement have no statistically significant effect on opportunity capture. Fourth, information seeking and opportunity capture have a significant effect on perceived entrepreneurship prospects, and information combination has no significant effect on statistically recognized entrepreneurship prospects. This research examined the effects of the entrepreneurship education and role model of university students, which are the subjects of entrepreneurship education activities supported by universities and governments, and suggested implications related to the entrepreneurial potential of university students who did not entrepreneurship immediately because the perceived desire for and the perceived feasibility of entrepreneurship are formed.

• Journal of the Korea Society of Computer and Information
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• v.28 no.3
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• pp.177-187
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• 2023

This study aims to validate a tool evaluating MOOCs for higher education from the perspective of education service. Based on the results of related researches, a potential model for evaluating MOOCs (4 factors and 8 sub-factors) was made. An evaluation tool consisting of 18 survey items was delivered to 138 college students. After data cleaning, 136 surveys were used for exploratory factor analysis (principal component analysis. varimax rotation) and reliability analysis that confirmed the fitness of the potential model. Four exploratory constructs and seven sub-factors were extracted: Factor I was labeled as 'Systemic Learning Experience,' Factor II, 'Value Experience,' Factor III, 'Co-creation of Value Experience,' and Factor IV, 'High Order Learning Experience.' Reliability estimates using Cronbach's alpha indicated that the evaluation tool had good internal consistency. In conclusion, the evaluation tool for MOOCs in higher education was proven to be valid and reliable.

• Journal of Microbiology and Biotechnology
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• v.27 no.1
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• pp.92-100
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• 2017

Acetoin (AC) is a volatile platform compound with various potential industrial applications. AC contains two stereoisomeric forms: (3S)-AC and (3R)-AC. Optically pure AC is an important potential intermediate and widely used as a precursor to synthesize novel optically active materials. In this study, chiral (3R)-AC production from meso-2,3-butanediol (meso-2,3-BD) was obtained using recombinant Escherichia coli cells co-expressing meso-2,3-butanediol dehydrogenase (meso-2,3-BDH), NADH oxidase (NOX), and hemoglobin protein (VHB) from Serratia sp. T241, Lactobacillus brevis, and Vitreoscilla, respectively. The new biocatalyst of E. coli/pET-mbdh-nox-vgb was developed and the bioconversion conditions were optimized. Under the optimal conditions, 86.74 g/l of (3R)-AC with the productivity of 3.61 g/l/h and the stereoisomeric purity of 97.89% was achieved from 93.73 g/l meso-2,3-BD using the whole-cell biocatalyst. The yield and productivity were new records for (3R)-AC production. The results exhibit the industrial potential for (3R)-AC production via whole-cell biocatalysis.