• Journal of Life Science
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• v.31 no.12
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• pp.1120-1127
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• 2021

Depression has a negative impact on social functioning due to its high prevalence and increased suicide rate, and is a disease with a high economic burden. Depression is related to diverse brain-related phenomena, such as neuroinflammation, synaptic dysfunction, and cognitive deficit. As antidepressant drugs used in clinical trials have shown poor therapeutic effects, antidepressant drugs that show rapid efficacy urgently need to be developed. Although studies on various genes, proteins, and signaling pathways related to depression have been conducted, the pathogenesis of depression has not been clearly elucidated. Sirtuin 1 is a nicotinamide-adenine dinucleotide- (NAD+-) dependent histone deacetylase and is involved in cell differentiation, apoptosis, autophagy, and cancer metabolism. Recent genetic studies found that sirtuin 1 is a potential target gene for depression. In addition, preclinical studies reported that sirtuin 1 signaling affects depression-like behavior. In this review, we attempt to present up-to-date knowledge of depression and sirtuin 1. We describe the various roles of sirtuin 1 in the regulation of glial activation, circadian rhythm, neurogenesis, and cognitive function and the effects of its expression on depression. Further, we discuss the effect of sirtuin 1 on the impairment of neural plasticity, one of the key mechanisms of depression, and the associated mechanisms of sirtuin 1.

• Journal of Korea Entertainment Industry Association
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• v.15 no.8
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• pp.351-361
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• 2021

This study was conducted to identify the factors of hypertension treatment in Gwangju and to establish a hypertension cure rate management plan by using local community health surveys to provide the hypertension cure rate management plan centering around the wellness local community. The research collected 13,714 Gwangju research data among a total of 685,820 local community health surveys of KDCA (Korea Disease Control and Prevention Agency) from 2017 to 2019. Among the data, 2,941 subjects, those with diagnosed hypertension aged over 30, were selected and analyzed through SAS 9.4, SAS Enterprise Miner 15.1. The results are as follows. The differences in hypertension diagnosis cure rate in Gwangju based on the subjects' socioeconomic characteristics were shown in gender, age, marital status, level of educational attainment, economic activity status, and monthly income. The significant differences in hypertension cure rate based on health behavior characteristics were shown in current smoking, monthly alcohol consumption, high-risk drinking, breakfast, recognition of good health level, diabetes and treatment, annual unmet medical needs, and annual health center use. As a result of the logistic regression analysis and interactive decision tree analysis to identify the factors affecting hypertension treatment, the research found that the factors that appear are age, marital status, diabetes and treatment, and annual unmet medical needs. Accordingly, to increase the recognition of the importance of hypertension treatment to people of young ages and not to develop complications, public health-educational effort in Gwangju is needed with an effective preparation plan.

• Journal of Korean Home Economics Education Association
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• v.33 no.4
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• pp.1-13
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• 2021

The purpose of this study is to identify trends and potential themes of research on consumption of children and adolescents for 20 years by analyzing keywords. The keywords of 869 studies on consumption of children and adolescents published in journals listed in Korean Citation Index were analyzed using text mining techniques. The most frequent keywords were found in the order of youth, youth consumers, consumer education, conspicuous consumption, consumption behavior, and character. As a result of analyzing the frequency of keywords by dividing into five-year periods, it was confirmed that the frequency of consumer education was significantly higher betwn 2006 and 2010. Research on ethical consumption has been active since 2011, and research has been conducted on various topics instead of without a prominent keyword during the most recent 5-year period. Looking at the keywords based on the TF-IDF, the keywords related to the environment and the Internet were the main keywords between 2001 and 2005. From 2006 to 2010, the TF-IDF values of media use, advertisement education, and Internet items were high. From 2011 to 2015, fair trade, green growth, green consumption, North Korean defector youths, social media, and from 2016 to 2020, text mining, sustainable development education, maker education, and the 2015 revised curriculum appeared as important themes. As a result of topic modeling, eight topics were derived: consumer education, mass media/peer culture, rational consumption, Hallyu/cultural industry, consumer competency, economic education, teaching and learning method, and eco-friendly/ethical consumption. As a result of network analysis, it was found that conspicuous consumption and consumer education are important topics in consumption research of children and adolescents.

• Journal of the Korea institute for structural maintenance and inspection
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• v.27 no.1
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• pp.1-8
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• 2023

At construction sites, interest in the production of precast materials is increasing due to off-site conditions due to changes in construction site conditions due to increased labor costs and the Act on the Punishment of Serious Accidents. In particular, the precast prestressed hollow slab has a hollow shape in the cross section, so structural performance is secured by reducing weight and controlling deflection through stranded wires. With the application of structural standards, the urgency of securing fire resistance performance is emerging. In this study, a fire-resistance cross section was developed by reducing the concrete filling rate in the cross section and improving the upper and lower flange shapes by optimizing the hollow shape in the cross section of the slab to have the same or better structural performance and economic efficiency compared to the existing hollow slab. The PC hollow slab to which this was applied was subjected to a two-hour fire resistance test using the cross-sectional thickness as a variable, and as a result of the test, fire resistance performance (load bearing capacity, heat shielding property, flame retardance property) was secured. Based on the experimental results, it is determined that fire resistance modeling can be established through numerical analysis simulation, and prediction of fire resistance analysis is possible according to the change of the cross-sectional shape in the future.

• Korean Journal of Culture and Social Issue
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• v.29 no.3
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• pp.405-427
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• 2023

This study aimed to identify demographic variables(gender, age group, occupation, living arrangement, economic level, respiratory and chronic diseases, previous medical history), COVID-19 variables(COVID-19 prevention behavior, frequent use of media to obtain COVID-19 information), and psychological behavioral variables(depression, anxiety, loneliness, and increased drinking). From February to March 2021, an online survey of adults was conducted, and a total of 1,434 data were used for analysis. 260 out of 1,434 people were confirmed to have suicide ideation, the prevalence of suicide ideation among adults during the COVID-19 was 18.1%. Logistic regression analyses indicated elevated odds of suicidal ideation among individuals in their 20s and 30s, those living alone, exhibiting fewer COVID-19 preventive behaviors, consuming COVID-19 information more frequently through media, and reporting higher levels of loneliness. Furthermore, within the group experiencing depression, anxiety, and increased drinking, greater levels of these factors correlated with higher odds of suicidal ideation. Based on the results, implications and significance of the study were discussed.

• Journal of Korean Tunnelling and Underground Space Association
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• v.25 no.2
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• pp.43-63
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• 2023

With the concentration of the population in the city center and the saturation of the structures on the ground, the development of the underground structures becomes important and the construction of an adjoining tunnel that can reduce the overall problems is respected. In addition, it is necessary to apply the reinforcement construction method for the pillar part of the adjacent tunnel that can secure stability, economy and workability of the site. In this study, the tunnel pillar reinforcement method using prestress and grouting was reviewed. There are various reinforcement methods that can compensate for the problems of the side tunnel, but as the tunnel pillar construction method using prestress and grouting is judged to be excellent in field applicability, stability and economic feasibility, theoretical and numerical analysis of the actual behavior mechanism are conducted. Numerical analysis is divided into PC stranded wire + steel pipe reinforcement grouting + prestress (Case 1), pillar part tie bolt reinforcement (Case 2), pillar part non-reinforcement (Case 3) under the same ground conditions, and the maximum value of the celling displacement, internal displacement, and member force, the stability was confirmed. Through numerical analysis, it was confirmed that Case 1 which reinforced the PC stranded wire, was the best construction method and if it is verified and supplemented through field experiments later, it will be possible to derive superior results in terms of displacement control and member force than the currently applied reinforcement method was judged.

• Korean small business review
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• v.41 no.3
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• pp.107-128
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• 2019

The Employment Permit System (EPS), a system of bringing in low-skilled foreign workers, has been implemented since 2004 to relieve labor shortages in SMEs. Despite the increasing number of foreign workers under this system, due to lack of research we have very limited managerial understanding. Moreover, previous studies focused on economic or legal perspectives, which calls for a different perspective of business and management. In this study, we examined how to foster organizational citizenship behaviors (OCB) of low-skilled immigrant workers at the workplace by integrating two analytical frames-social support from management studies and cultural adjustment from immigrant literature. We tested our model using a sample of 661 immigrant workers from 11 countries working in Korea. Our results indicated that, social support perception triggered not only a direct effect on organizational citizenship behaviors of immigrant workers but also indirect effects via the level of cultural adaptation. Our findings indicated that two views are all meaningful in explaining OCB of immigrants, and provided practical implications to SMEs using EPS.

• Korean Association of Arts Management
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• no.52
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• pp.5-37
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• 2019

Despite a copious volume of work on the relationship between social class and cultural consumption, scholars have paid scant attention to the increasingly apparent observation that a vast majority of the population exhibits indifference toward fine arts regardless of one's socio-economic status. Much of the prior literature on cultural consumption has treated the public's indifference to fine arts not as a distinct analytical category that deserves an explanation of its own, but simply as the opposite of "likes" or the act of consumption, let alone being disentangled from the concept of "dislikes" in taste-formation and consumption behavior. In this paper, we suggest that the seemingly increasing trend toward indifference to fine arts, especially among those who are part of the well-educated and economically well-off, merits close scholarly attention on its own term. As an initial step toward this endeavor, we explore the factors behind indifference toward fine arts among Korean middle-class, using the ground theory method. Our interview findings reveal that much of indifference toward fine arts is attributable to the lack of tastes in fine arts and artistic competence. Our results suggest that research drawing on Bourdieu's theory and Peterson's omnivore hypothesis needs to be further revised through an in-depth investigation of the institutional and societal contexts where art education takes place in Korea. We discuss the implications of our findings for policy-making in the cultural and artistic sphere.

• Tuberculosis and Respiratory Diseases
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• v.86 no.2
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• pp.82-93
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• 2023

Tuberculosis (TB) is a significant public health concern. Globally, TB is among the top 10 and the leading cause of death due to a single infectious agent. Providing standard anti-TB therapy for at least 6 months is recommended as one of the crucial strategies to control the TB epidemic. However, the long duration of TB treatment raised the issue of non-adherence. Non-adherence to TB therapy could negatively affect clinical and public health outcomes. Thus, directly observed therapy (DOT) has been introduced as a standard strategy to improve anti-TB medication adherence. Nonetheless, the DOT approach has been criticized due to inconvenience, stigma, reduced economic productivity, and reduced quality of life, which ultimately could complicate adherence issues. Apart from that, its effectiveness in improving anti-TB adherence is debatable. Therefore, digital technology could be an essential tool to enhance the implementation of DOT. Incorporating the health belief model (HBM) into digital technology can further increase its effectiveness in changing behavior and improving medication adherence. This article aimed to review the latest evidence regarding TB medication non-adherence, its associated factors, DOT's efficacy and its alternatives, and the use of digital technology and HBM in improving medication adherence. This paper used the narrative review methodology to analyze related articles to address the study objectives. Conventional DOT has several disadvantages in TB management. Integrating HBM in digital technology development is potentially effective in improving medication adherence. Digital technology provides an opportunity to improve medication adherence to overcome various issues related to DOT implementation.

• 한국노년학
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• v.31 no.3
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• pp.673-689
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• 2011

It is a qualitative study based on a focus group with an aim to figure out elderly people's experiences in health inequality in vulnerable health zones in agriculture and fisheries areas. Of eups, myeons and dongs selected as 40 vulnerable areas where standardized death rates had continued to be high from 2004 to 2007 in 20 counties and cities in Gyeongsang-do, 15 agriculture and fisheries areas were randomly chosen to extract 8 to 10 elderly people. Explanations were given to study subjects, and 7 to 8 people who agreed to take part in the study joined a regional focus group. Contents of interviews were analyzed with a phenomenological method by Colaizzi (1978) in order to accurately describe pertinent phenomena. The study has found four categories including ecological environmental problems, insufficient services for local community & harmful environmental problems, worsening economic conditions and insufficient health care management in terms of health behavior.