• Journal of the Korean Institute of Telematics and Electronics S
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• v.35S no.6
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• pp.1-8
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• 1998

This paper presents an asynchronous DS/CDMA multiuser detector, which is a two stage, symbol-by-symbol scheme consisting of conventional detectors followed by linear decorrelating detectors. The conventional detector first makes temporal decisions and the detected symbols are delayed by one symbol period to be used for the selection of decorrelating bases in the subsequent decorrelaing detection stage. It also employs a bank of early-late correlators in place of a bank of single correlators taking the small offset of chip timing asynchronism into account. The proposed detector requires only the coarse knowledge of relative time delays of interfering users and is suitable for digital implementation. To verify the detector performance, the analytical BER performance will be given and compared with the simulation results for BPSK DS/CDMA signals in AWGN channel. While the performance of the proposed detector will be analyzed for time-limited signal, the simulation is carried out for both the time-limited and band-limited signals. As can be seen in the simulation results, the proposed scheme shows good results.

• Convergence Security Journal
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• v.13 no.3
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• pp.71-77
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• 2013

In our country security industry biz model analysis methodology fragmentary theory exists, but it is hard to find a comprehensive analysis methodology. Biz model analysis IT companies the external factors and internal factors to integrate the information gathered about the comprehensive analysis of the development of an information system are required. Information support system early in the software architecture of the system design decisions early decision as the design, development, testing, maintenance, has a lasting impact on the project as a guideline in the development of a framework of design abstraction. BMO evaluation support information systems architecture designs system purposes. The mission must support the execution. Information system stakeholders to determine the mission and the environment. All information systems architecture shall have architecture. Technology architecture should be documented with each other can be used. Determine the architecture based architecture descriptions are presented.

• Genomics & Informatics
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• v.15 no.1
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• pp.28-37
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• 2017

Obesity is a highly prevalent, chronic disorder that has been increasing in incidence in young patients. Both epigenetic and genetic aberrations may play a role in the pathogenesis of obesity. Therefore, in-depth epigenomic and genomic analyses will advance our understanding of the detailed molecular mechanisms underlying obesity and aid in the selection of potential biomarkers for obesity in youth. Here, we performed microarray-based DNA methylation and gene expression profiling of peripheral white blood cells obtained from six young, obese individuals and six healthy controls. We observed that the hierarchical clustering of DNA methylation, but not gene expression, clearly segregates the obese individuals from the controls, suggesting that the metabolic disturbance that occurs as a result of obesity at a young age may affect the DNA methylation of peripheral blood cells without accompanying transcriptional changes. To examine the genome-wide differences in the DNA methylation profiles of young obese and control individuals, we identified differentially methylated CpG sites and investigated their genomic and epigenomic contexts. The aberrant DNA methylation patterns in obese individuals can be summarized as relative gains and losses of DNA methylation in gene promoters and gene bodies, respectively. We also observed that the CpG islands of obese individuals are more susceptible to DNA methylation compared to controls. Our pilot study suggests that the genome-wide aberrant DNA methylation patterns of obese individuals may advance not only our understanding of the epigenomic pathogenesis but also early screening of obesity in youth.

• Asian-Australasian Journal of Animal Sciences
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• v.28 no.5
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• pp.686-690
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• 2015

The adrenergic receptor beta 2 (ADRB2) plays a role in various physiological responses of the muscle to exercise, such as contraction and relaxation. Given its important role in muscle function, we investigated the structure of the horse ADRB2 gene and its expression pattern after exercise to determine if it can serve as a putative biomarker for recovery. Evolutionary analyses using synonymous and non-synonymous mutation ratios, were compared with other species (human, chimpanzee, mouse, rat, cow, pig, chicken, dog, and cat), and revealed the occurrence of positive selection in the horse ADRB2 gene. In addition, expression analyses by quantitative polymerase chain reaction exhibited ubiquitous distribution of horse ADRB2 in various tissues including lung, skeletal muscle, kidney, thyroid, appendix, colon, spinal cord and heart, with the highest expression observed in the lung. The expression of ADRB2 in skeletal muscle was significantly up-regulated about four folds 30 minutes post-exercise compared to pre-exercise. The expression level of ADRB2 in leukocytes, which could be collected with convenience compared with other tissues in horse, increased until 60 min after exercise but decreased afterward until 120 min, suggesting the ADRB2 expression levels in leukocytes could be a useful biomarker to check the early recovery status of horse after exercise. In conclusion, we identified horse ADRB2 gene and analyzed expression profiles in various tissues. Additionally, analysis of ADBR2 gene expression in leukocytes could be a useful biomarker useful for evaluation of early recovery status after exercise in racing horses.

• Proceedings of the Korean Society of Developmental Biology Conference
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• 1998.07a
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• pp.12-18
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• 1998

Tremendous progress has been made over the past quarter-century studying the genetics of gametogenesis and the resulting gametes and embryos. Studies merging molecular techniques and conventional cytogenetics are now beginning to bridge the gap between what we have learned about the meiotic process in males and females and what we know of the mitotic chromosomes of zygotes. Numerical abnormalities in sperm, oocytes and embryo can now diagnosed by fluorescence in situ hybridization (FISH). "At risk" couples can, therefore, have only unaffected embryos replaced in the sterus and avoid the possibility of terminating a pregnancy that might only be diagnosed as affected later gestation. Single-cell genetic analysis has also provided powerful tools for studying genetic defects arising during early human development. Recent studies of sperms, oocytes and cleavage-stage human embryos have revealed an unexpectedly high incidence. These genetic abnormalities are likely to contribute to early pregnancy loss and have important implications for improving pregnancy rates in infertile couples by assisted reproduction. The widespread use of preimplantation genetic diagnosis (PGD) awaits further documentatio of safety and accuracy. Other issues also must be addressed. First, the ethical issues regarding germ cell and embryo screening must be addressed including what diseases are serious enough to warrant the procedure. Another concern is the use of this technology for non-genetic disorders such as gender selection. Finally, the experimental nature of these procedure must continually be discussed with patients, and long-term follow-up studies must be undertaken. Development of more accurate and less expensive assays coupled with improved assisted reproductive technology success rates may make PGD a more widely use clinical tool. The future awaits these development.velopment.

• Archives of Plastic Surgery
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• v.41 no.4
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• pp.394-397
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• 2014

Background Proximal interphalangeal joint (PIPJ) dislocations represent a significant proportion of hand clinic visits and typically require frequent follow-ups for clinical assessment, orthotic adjustments, and physiotherapy. There are a large number of treatment options available for PIPJ dislocations, yet no prospective or controlled studies have been carried out, largely due to the diversity of the various types of injuries. Methods We retrospectively reviewed all the PIPJ dislocations in our institution over a five-year period and directly compared the different splinting techniques that we have used over this time frame. Results There were a total of 77 dislocations of the PIPJ (57 men and 20 women) that were included in our study. We found that our management has shifted gradually from complete immobilisation to controlled early mobilisation with figure-of-eight splints. Following treatment, the range of motion of the PIPJ in the figure-of-eight group was significantly greater than that in the other three methods (P<0.05) used. There were significantly fewer hospital visits in the figure-of-eight splint group than in the other treatment groups. Conclusions The treatment of PIPJ dislocations has undergone a significant evolution in our experience. Early controlled mobilisation has become increasingly important, and therefore, splints have had to be adapted to allow for this. The figure-of-eight splint has yielded excellent results in our experience. It should be considered for all PIPJ dislocations, but careful patient selection is required to achieve optimum results.

• Journal of the Korean Society of Environmental Restoration Technology
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• v.6 no.5
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• pp.48-58
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• 2003

This study was carried out to select proper species for early stage replantation in granite forest road cut-slope. From one to thirteen year elapsed forest roads in five regional areas of Chungcheong-do and Kyungsangbuk-do, sample plots were selected, and their vegetations and environmental factors were investigated. Soil organic matter, total nitrogen, soil moisture content, and bulk density in the granite weathering soils were below 0.5%, 0.02%, 10%, and above 1.2g/$cm^3$, respectively. The environmental factors affecting distribution of species in the granite forest road were the elapsed year, elevation, cut-slope aspect, and cut-slope. Sowing plants of Dactylis glomerata, Lolium perenne, and Eragrostis curvula were found in the early stage of forest road-cut. Annual herbs of Youngia denticulata, Erigeron annuus, etc. were found in the 2-3 years elasped forest road-cut. Perennial herbs of Artemisia princeps var. orientalis, Miscanthus sinensis, etc., parachute woody plants of Weigela subsessilis, Pinus densiflora, etc., and gravitative trees of Prunus sargentii, Lindera obtusiloba, Quercus sp., etc. were found in the forest road cut-slope after 3 years of road-cut. Leguma of Lespedeza cureata, Amorpha fruticosa, Lespedeza bicolor, Pueraria thunbergiana, Albizzia julibrissin, etc., herbs of Artemisia keiskeana, Artemisia princeps var. orientalis, Miscanthus sinensis, etc., and woody plants of Rubus crataegifolius, Weigela subsessilis, Zanthoxylum schinifolium, Pinus densiflora, etc. were considered as proper species for replantation in granite forest road cut-slope.

• Journal of the Korea institute for structural maintenance and inspection
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• v.18 no.5
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• pp.19-26
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• 2014

Concrete guide rail and median barrier are an attached RC member, however they are vulnerable to cracking due to slip form construction and large surface of member. In this study, causes and pattern of cracking are analyzed through assessment and NDT (Non-Destructive Technique) evaluation for concrete guide rail and median barrier on highway structure. For this work, analysis on drying shrinkage and hydration heat are performed considering installation period, and plastic shrinkage is also analyzed considering their environmental conditions. From the evaluation, plastic settlement around steel location, drying/ plastic shrinkage, and aggregate segregation are inferred to be the main causes of cracking in the structures. The crack causes and patterns are schematized and techniques of crack-control are suggested. Furthermore concrete guide rail/ median barrier in the bridge on the sea are vulnerable to cracking at early age so that special attentions should be paid at the stages of material selection and construction.

• Journal of the Korea Society of Computer and Information
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• v.13 no.6
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• pp.59-68
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• 2008

In this paper, we propose a method for selecting meaningful event packets from which can receive before anything else from seismograph according to allotted priority and estimate epicenter using selected packets. Event packets which received from each station will be evaluated with their onset time, signal period and SNR by statistical method and will be selected packets related with real earthquake's P-wave. And estimated epicenters using by 'Application of epicenter estimation using first P arrivals'. With local earthquakes occurred in 2007 were announced by KMA, collected event packets on earthquake happened date and selected p-wave related packets and estimated epicenter. After result of experiment, if an earthquake occurred within seismic networks, can estimate epicenter with small misfits just after event packets arrived from above 4 stations. Considering average distance of each station, in case of using all stations' data include other organization, can estimate and alert rapidly. It show this method is useful when construct a local earthquake early warning system later.

• Polymer(Korea)
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• v.39 no.2
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• pp.235-239
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• 2015

In this work, we evaluated catalytic activity of LiOH, $Cu(acac)_2$ and n-butyltin hydroxide oxide hydrate in the early stage of the melt transesterification of isosorbide and bisphenol A as diol monomers and diphenylcarbonate for the melt polymerizaiton of polycarbonate. $Cu(acac)_2$ proved to be the most active catalyst for homopolymerization process, while the catalytic activity of LiOH was higher than the others in case of melt copolymerization depending on the catalytic mechanism and chemical structure of catalyst. We suggested that evaluation of catalytic activity can be used for selection of catalyst system in bio-based copolymerization of polycarbonate.