• Proceedings of the Korean Society of Applied Pharmacology
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• 2007.11a
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• pp.11-15
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• 2007

Metabolomics is an emerging technology which makes it possible to evaluate change of biological system in response to the physiological, environmental alterations. It has advantages in the simplicity and sensitivity to analyze metabolites since the researcher can use cutting edge instrument, such as mass spectrometry and simple sample preparation method compared to genomics or proteomics. Nowadays this technology has been tried in pharmaceutical area to investigate toxicity and efficacy of drug candidates and drugs in preclinical test. The metabolomic applications on the pharmaceutics for early prediction on toxicity and efficacy are described in this presentation. The multivariate analysis to get metabolic fingerprinting and its relations with the physiological changes are investigated with several drugs. Feasibility of metabolomic application for pharmaceutical area would be suggested from those researches.

• International Journal of Advanced Culture Technology
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• v.9 no.4
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• pp.102-109
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• 2021

Since the 4th Industrial Revolution is implemented based on superintelligence, new insights must be provided through convergence studies with other fields to find optimal solutions to create new ideas. In this paper, we intende to present improvement measures for probability and statistical education, which is an athlete's subject on data analysis and processing in the ICT(Information & Communication Technologies) field in the era of superintelligence of the 4th industrial revolution. This paper aims to strengthen competitiveness through early development and commercialization of new technologies by presenting probabilities and statistical curriculums that require linkage in the ICT field. Second, it is necessary to present an educational system diagram linking probabilities and statistics in the ICT field to prepare a mid- to long-term response strategy for ICT education in response to innovative changes. Third, through a survey, we intend to present an effective educational operation plan linking probability and statistics to ICT major subjects by analyzing the perception of probability, statistical importance, and utilization of majors in this field.

• Journal of the Korean Society of Marine Environment & Safety
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• v.23 no.6
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• pp.684-689
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• 2017

We examined the possibility of developing an early monitoring system using the shell valve movement activity of Pacific oyster (Crassostrea gigas) for early detection of low salinity water in coastal areas. At salinity levels of 30 psu and 20 psu, SVMs were detected $7.32{\pm}3.21times/hr$ and $7.11{\pm}3.90times/hr$, respectively, The patterns and times of SVMs were not significantly different between the two experiment phases. However, at 10 psu and 5 psu, shell valves were observed to be permanently closed in all experiments. Under combined condition (Group 1: temperature $15^{\circ}C$ ${\times}$ salinity 15 psu), SVMs were observed from 20 psu to 30 psu over a 2 - 3 hr period, and then remained closed. In Group 2 (temperature $30^{\circ}C$ ${\times}$ salinity 15 psu), SVMs were observed, which indicated that the physiological condition of the oysters reached a critical point. Thus, it may be possible to utilize SVMs as an early warning signal for low salinity water.

• Journal of Families and Better Life
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• v.32 no.2
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• pp.53-75
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• 2014

The purpose of this study was to develop and validate the "Authentic Parental Competence Scale" for mothers with school-age children. Based on a literature review, the study found that 'authentic parental competence' could be divided into parenting comperence, self-system competence, and social competence. In addition, the scale comprised three factors consisting of 43. The study collected data through behavior event interview(BEI), focus group interview(FGI), and three times Delphi investigation. The scale for mothers of school-age children consisted of a total of 129 items, which included three different dimensions (knowledge, skill, and attitude), and four factors were extracted from factor analysis following a survey of 362 mothers. The factors were labeled as "ability of developmental positive parenting," "ability of playing a role as a citizen and making social contributions," "ability of self-understanding and interpersonal relations," and "ability of self-growth and self-determination." In addition, the results revealed that the "Authentic Parental Competence Scale" showed an appropriate level of construct validity, reliability of the scales, distribution of item response, and item discrimination.

• Land and Housing Review
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• v.2 no.3
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• pp.227-238
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• 2011

There are similarities between Korea and Japan in terms of national planning and development system and housing policies. Japan has suffered from great shifts of social and economic systems due to skyrocketing land prices for three times and the collapse of the bubble economy after the Second World War. The study reviews historically important changes in the national territory and housing policies for last 60 years in Japan. It also investigates changing trends and characteristics of many socioeconomic indicators with regard to population, housing and other fields in response to these policies. First of all, Japan has experienced significant economic growth before and after the 1960's, and the era of national rebuilding projects in the 1970's. After then, the period of the bubble economy has emerged since 1980; however, it suffered from skyrocketing land values between the late 1980's and the early 1990's, and the collapse of Japanese bubble economy in the early 1990's. In response, many urban regeneration policies and projects were proposed to recover the national economy since 2000. It is found that these national territory development and housing supply policies throughout the country have been influenced by the changing characteristics of social and economic conditions. Since the housing supply ratio in 1968 reached up to around 100% on average, Japan has been focusing attention to improving the residential and living quality for existing housing stock rather than supplying new housing units through large-scale new town projects. These experiences are full of helpful suggestions for our future housing and urban regeneration policies as we reach to more than 100% of housing supply ratio on average.

• Journal of Convergence Society for SMB
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• v.5 no.2
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• pp.33-38
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• 2015

The damage to the security is increasing as public key-based ISP secure payment service is used in online banking payment system. Security technology aspect to ISP secure payment security has no special problems. But, security damage that occurs due to the simplicity of the payment system is a problem. In this paper, we propose response and plan for ISP secure payment service to minimize the damage that occurs due to the simplicity of a security settlement system. Proposed scheme is applicable to various billing systems such as secure payments, online payment, mobile payment, credit card. Proposed scheme is characterized in that can stably support the capabilities of the new billing system. Also, proposed scheme is to analyze the various security threats arising from the payment of the financial services and to describe response and plan technology.

• Transactions of the Korean Society of Automotive Engineers
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• v.9 no.5
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• pp.54-61
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• 2001

It is reported that during the cold starting, especially in gasoline engine, the engine response and the effect of HC emission can be improved by prompting atomization and reducing the quantity of fuel adhered to the range of injector tip, inlet port, and inlet valve. The purposes of this study are to promote atomization of fuel before air-fuel mixture in the inlet port. In order to achieve its goal, the glow plug is to evaluate the feasibility of for the early fuel evaporator and the spray behavior characteristics of gasoline, injected on the surface of glow plug with room temperature(2$0^{\circ}C$) and high temperature(25$0^{\circ}C$) is to examine. Particle motion analysis system(PMAS) was used to measure the SMD and the dropsize distribution of impinging spray and free spray. The results of this experiment, evaporation rate of impinging spray was higher than that of free spray, and the higher evaporation rate win, the smaller peak dropsize was. Especially, during early spray SMD of impinging spray was still smaller than that of fee spray.

• Journal of Broadcast Engineering
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• v.27 no.1
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• pp.80-90
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• 2022

Currently, the domestic early warning system is issued differently for each disaster, and is operated independently by relevant organizations from central government to local governments. Representative domestic disaster warning systems include disaster broadcasting using CBS(Cell Broadcasting Service) and DMB(Digital Multimedia Broadcasting) Automatic Emergency Alert Service, DITS(Disaster Information Transform System) transmitted and displayed on TV screens, automatic response system, automated rainfall warning system, and disaster message board. However, due to the difference in the method of issuing each emergency alert at the site of an emergency disaster, the alerts are issued at different times for each media, and the delivered content is also not integrated. If these systems are integrated, it is expected that damage to people's property and lives will be minimized by sharing and integrated management of disaster information such as voice, video, and data to comprehensively judge and make decisions about disaster situations. Therefore, in this study, we present a plan for the integration of the disaster warning system along with the analysis of the operation status of the domestic early warning system.

• Development and Reproduction
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• v.17 no.4
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• pp.321-327
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• 2013

The innate immune system is the only defense weapon that invertebrates have, and it is the fundamental defense mechanism for fish. The innate immune response is important in newly hatched flounders because it is closely involved in the initial feeding phase, which is why it is essential for survival during the juvenile period. The expression analysis of genes involved in the innate immune response in the olive flounder (Paralichthys olivaceus) in the days after hatching is incomplete. Therefore, we have begun to examine the expression patterns of genes specifically induced during the development of the innate immune system in newly hatched flounders. Microscopic observation showed that pronephron formation corresponded with the expression of perforin-encoding gene. These results suggest that perforin plays a vital role in the innate immunity of the kidney during developmental stages. Perforin expression was strong at the start of the development of the innate immune response, and continued throughout all the development stages. Our findings have important implications with respect to perforin's biological role and the evolution of the first defense mechanisms in olive flounder. Further studies are required to elucidate the perforin-mediated innate immunity response and to decipher the functional role of perforin in developmental stages.

• Journal of the Korea Convergence Society
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• v.8 no.7
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• pp.323-330
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• 2017

Emotion in early childhood has been observed to make an important effect on behavioral development. The teacher has coached to develop good behavior based on considering emotional response rather than rational response. This study was to determine significance of emotional coaching for behavior development according emotion recognized by non-verbal measurement system developed specially in this study. The participants were 44 people and were asked to study in four experimental situation. The experiment was designed to four situation such as class without coaching, behavioral coaching, emotion coaching, and emotion coaching based on emotional recognition system. The dependent variables were subjective evaluation, behavioral amplitude, and HRC (Heart Rhythm Coherence) of heart response. The results showed the highest positive evaluation, behavioral amplitude, and HRC at emotion coaching based on emotional recognition system. In post-doc analysis, the subjective evaluation showed no difference between emotion coaching and system based emotion coaching. However, the behavioral amplitude and HRC showed a significant response between two coaching situation. In conclusion, quantitative data such as behavioral amplitude and HRC was expected to solve the ambiguity of subjective evaluation. The emotion coaching of teacher using emotional recognition system was can be to improve positive emotion and psychological stability for children.