• Journal of the Korean Society of Safety
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• v.32 no.2
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• pp.38-45
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• 2017

This paper is an experimental study to find an optimal detection method for detecting fire early in a rack-type warehouse stored with goods. In this study, we constructed rack-type structure with the fourth floor of 13.5 m high and conducted fire experiments which were to measure flow of heat/smoke in rack-type structure and response time of fire detectors. The detectors used at experiments were fixed temperature type detectors, rate of rise detectors, photoelectric smoke detectors, air sampling smoke detectors and flame detectors. The used ignition sources are n-heptane fire for response of heat detection and cotton fire for response of smoke detection. The fixed temperature type detectors, rate of rise detectors and photoelectric detectors were installed to every rack level respectively. The results show that the rate of rise detector should be installed every 2 levels and photoelectric smoke detector should be installed every 4 levels for the early stage fire detection. Air sampling smoke detectors can detect fire early in response to control of sensitivity, but there is a problem in false alarm. The fixed temperature detector is not suitable for early stage fire detection in warehouse and flame detector not worked if flame is not visible, so it need to install combination with other detector.

• Journal of the Korean Society for Marine Environment & Energy
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• v.3 no.1
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• pp.3-24
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• 2000

The provability of major oil spill acidents around Korean coast is very high due to increase of sea traffic and decrease of quality of ships crews and increase of the old-ship. The Strategies of establishment of a advanced response management system against this mass pollution incident are as follows;. 1. Development of Regional Contingency Plan, which is scientifically illuminated, in order to implement the National Contingency Plan efficiently. 2. Early completion of a national response capability twenty thousand tons. 3. To strengthen training and exorcise specialized in the field of marine pollution response. 4. Establishment of a system of response cooperation among neighbor countries by promoting the NOWPAP tasks etc. The response policy in the 21th century should be concentrated to promote a practicle response capability through response operation scientifically specialized and internationalized by establishing the advanced response system early.

• Biotechnology and Bioprocess Engineering:BBE
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• v.10 no.5
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• pp.444-450
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• 2005

Epidermal growth factor (EGF) activates many intracellular effector molecules, which subsequently influence the expression levels of many genes involved in cell growth, apoptosis and signal transduction, etc. In this study, the early response of gene expressions due to EGF treatment was monitored using oligonucleotide DNA microarrays in rat schwannoma cell lines. An immunoblotting experiment showed the successful activation of EGF receptors and an effector protein, STAT5, due to EGF treatment. The microarray study showed that 35 genes were significantly induced and 2 were repressed within 60 min after the treatment. The list of induced genes included early growth response 1, suppressor of cytokine signaling 3, c-fos, interferon regulatory factor 1 and early growth response 2, etc. According to the microarray data, six of these were induced by more than 10-fold, and showed at least two different induction patterns, indicating complicated regulatory mechanisms in the EGF signal transduction.

• The Korean Journal of Physiology
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• v.15 no.2
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• pp.97-101
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• 1981

The early plasma gastrin responses to single oral glucose or casein solution were studied in the same normal subjects on different days. After an overnight fast, glucose or casein solution was ingested within few minutes at the breakfast time. The plasma gastrin responses to these solutions were compared and contrasted with the concentration when the subjects received glucose solution intravenously. Results were as follows: 1) Rapid intravenous glucose infusion did not produce any changes in the plasma gastrin concentration. 2) Plasma gastrin concentration rose and peaked within 10 minutes after an oral liquid ingestion and then decreased substantially by 15 minutes, but remained slightly above fasting levels at 60 minutes. 3) There was no significant difference between the mean plasma gastrin concentrations after glucose of casein ingestion, but each fluid produced a significant increase in serum gastrin above fasting levels. 4) The subjects who produced high plasma gastrin response to glucose solution did so to casein solution. Conversely a low response to one solution reflected a low response to the other solution. 5) From the above results, authors discussed that individual responsibility rather than the sorts of meals is the factor in the determination of the magnitude of the early gastrin response.

• Proceedings of the Acoustical Society of Korea Conference
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• spring
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• pp.439-442
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• 2000

When we measure the acoustical properties of a room using multiple microphone system, it is important to grasp exact time delay of the early reflections from impulse response pair. But it is often very difficult to identify the early reflections in natural shape, because a waveform may be deformed due to the characteristics of a sound source loudspeaker, microphone and reflected wall and overlapping of plural waveform. In this paper to obtain more accurate and enough early reflections, we propose the brand-new five-channel sound receiving system and introduce peak-detecting algorithm. The system has microphones mounted at the origin and four points of a regular tetrahedron. The newly introduced peak-detecting algorithm can show exact peak position in each channel, in spite of deformation due to reflected walls, loudspeaker and microphone.

• International conference on construction engineering and project management
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• 2015.10a
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• pp.56-57
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• 2015

This study is to review and re-establish LH disaster response and safety management system of the construction site and rental apartment complex in order to make an effective response and minimize damage in the face of disaster. I suggest directions for the improvement of disaster management systems. To achieve this, I reviewed the existing disaster response organization and accept opinions of the operating department in order to constitute effective organization which respond quickly and efficiently in emergency, and assigned new roles and responsibilities at each organization. Furthermore, I setup and suggested response manuals for each possible disasters.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.15
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• pp.6663-6668
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• 2015

Background: Treatment failure in leukemia is due to either pharmacokinetic resistance or cell resistance to drugs. Materials and Methods: Gene expression of multiple drug resistance protein (MDR-1), multidrug resistance-related protein (MRP) and low resistance protein (LRP) was assessed in 45 pediatric ALL cases and 7 healthy controls by real time PCR. The expression was scored as negative, weak, moderate and strong. Results: The male female ratio of cases was 2.75:1 and the mean age was 5.2 years. Some 26/45 (58%) were in standard risk, 17/45(38%) intermediate and 2/45 (4%) in high risk categorie, 42/45 (93%) being B-ALL and recurrent translocations being noted in 5/45 (11.0%). Rapid early response (RER) at day 14 was seen in 37/45 (82.3%) and slow early response (SER) in 8/45 (17.7%) cases. Positive expression of MDR-1, LRP and MRP was noted in 14/45 (31%), 15/45 (33%) and 27/45 (60%) cases and strong expression in 3/14 (21%), 11/27 (40.7%) and 8/15 (53.3%) cases respectively. Dual or more gene positivity was noted in 17/45 (38%) cases. 46.5 % (7/15) of LRP positive cases at day 14 were in RER as compared to 100% (30/30) of LRP negative cases (p<0.05). All 8 (100%) LRP positive cases in SER had strong LRP expression (p=<0.05). Moreover, only 53.3% of LRP positive cases were in haematological remission at day 30 as compared to 100% of LRP negative cases (p=<0.05). Conclusions: Our study indicated that increased LRP expression at diagnosis in pediatric ALL predicts poor response to early treatment and hence can be used as a prognostic marker. However, larger prospective studies with longer follow up are needed, to understand the clinical relevance of drug resistance proteins.

• The Korean Journal of Ecology
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• v.18 no.3
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• pp.353-366
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• 1995

To study the relationship between the germination response and geographical distribution, the seeds of Rumex acetocella were collected from nine sites (Taegwallyong, Alps lodge, Kans'ong, Sokch'o, Chumunjin, Suwon, Taechon, Sukgok, Mokpo) of different latitudes and altitudes. The populations of Rumex acetocella were subdivided into four groups based on the characteristics of the seed germination. The first group of Rumex acetocella (Taegwallyong, Alps lodge) germinated rapidly in early spring, the second group (Suwon, Teachon) in late summer through early autumn, and the third group(Sukgok, Mokpo) slowly in late autuman with various conditions. The thermal time values needed for the germination rate of 10% to 60% for these three groups indicated that the germination rate was low at the lower latitude, while it was increased as the latitude elevated. The population of the fouth group (Kansong, Sokcho, Chumunjin) showed the narrow optimum temperature range of germination response and the highest thermal time value to germinate 10% to 30% of seeds. The seeds in the high latitude region with relatively mild winter germinated synchronously in early autumn. These different germination responses of Rumex acetocella to geographic variations were thought to be an ecological strategy to survive in different environmental conditions.

• Journal of the Korean Home Economics Association
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• v.50 no.1
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• pp.41-50
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• 2012

The purpose of this study was to examine the response pattern of children of early childhood (ages 4 to 5) to strangers' luring behaviors that suggest imminent crime. Data were collected from registrants offered by four kindergartens and daycare centers. Individual interviews were performed (N = 100) by using a questionnaire. Results were as follows: First, children of early childhood responded unfavorably to strange adults' kindness and request for aids. However, it was found that they did not make the right decision in relation to strange adults' luring behaviors that lead to crime when family related clues were manipulated. Second, children of early childhood responded favorably to strange adults' luring behaviors that are suggestive of criminal intent when candy, ice cream, and toys were offered. Especially, youngsters were more prone to be deceived by these indices than the older children. Third, older children responded unfavorably to strange adults' luring behaviors that suggest a criminal intent In addition, youngsters did not respond cleverly to strange adults' luring behaviors that suggest a criminal intent while showing a reluctant response.

• The Korean Journal of Nuclear Medicine
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• v.36 no.1
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• pp.64-73
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• 2002

FDG-PET has potential as an effective, non-invasive tool to measure tumor response to anticancer therapy. The changes in tumor FDG uptake may provide an early, sensitive guide to the clinical and subclinical response of tumors to cancer treatment, as well as functional assessment of residual viable tumor. This may allow the evaluation of subclinical response to anticancer drugs in early clinical trials and improvements in patients management. However, monitoring tumor responses with FDG-PET is still in its infancy. The methods of measurement of FDG uptake are currently diverse and timing with respect to anti cancer therapy variable. Therefore, there is a need for larger-scale trials along with standardized methodology and a collection of reproducibility data. The recent guideline from the European group seems to be the most comprehensive. In future, the combination of morphological and metabolic images may improve the quantitative nature of these measurements by relating tumor viability to total tumor mass. More data on sensitivity and specificity of FDG-PET technique are needed along with continued advancement of PET methodology.