• Journal of the Korean Society for Nondestructive Testing
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• v.23 no.3
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• pp.246-253
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• 2003

The initiation and growth of short fatigue cracks in the simulated aircraft structure with a series of rivet holes was detected by acoustic emission (AE). The location and the size of short tracks were determined by AE source location techniques and the measurement with traveling microscope. AE events increased intermittently with the initiation and growth of short cracks to form a stepwise increment curve of cumulative AE events. For the precise determination of AE source locations, a region-of-interest (ROI) was set around the rivet holes based on the plastic zone size in fracture mechanics. Since the signal-to-noise ratio (SNR) was very low at this early stage of fatigue cracks, the accuracy of source location was also enhanced by the wavelet transform do-noising. In practice, the majority of AE signals detected within the ROI appeared to be noise from various origins. The results showed that the effort of structural geometry and SNR should be closely taken into consideration for the accurate evaluation of fatigue damage in the structure.

• Journal of the Korean Institute of Gas
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• v.23 no.2
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• pp.17-27
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• 2019

In recent years, dangerous materials and gas leak accidents have been frequently occurred. The hazardous materials storage facility accidents are not rapidly controlled when a leak is detected, unlike other chemical plants can be controled. Externally, the human has to approach and respond to the source of leaking directly. As a result, the human and material damage are likely to larger result in the process. The current approach has been passive response after ringing the alarm. In this study, the suggested tracking system of the leak resource is designed system to track the resource actively by utilizing the mobile sensor robot platform, which can be made easily through recent rapid development technology, is verified through prototype system. Thus, a suggested system should pave the way for minimizing the spread and damage of the accident based on the exact site situation of the initial leak and quick and early measures.

• Journal of Digital Convergence
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• v.10 no.3
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• pp.121-126
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• 2012

In this paper, a way for maximum use of cancer risk assessment software system CARA which can assess cancer risks by using health related information only without doctor's diagnosis is proposed. A way of maximizing the usage of CARA with use of nation wide internet network is described along with the general description of CARA. If CARA is used, the damage causing by cancer can be reduced since it is possible to sort a group of people with high risks (before diagnosis at a hospital). Also, CARA is helpful for medical research by used as a tool to reveal correlations between personal information and cancers practically. Unlike other preexisting systems, CARA is a new system which can consider 30 different cancers simultaneously and it is very efficient for early detection of cancer.

• Annals of Clinical Neurophysiology
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• v.4 no.2
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• pp.137-139
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• 2002

Background : Subtle status epilepticus (SE) is an end-stage of convulsive SE. This phenomenon might be a clinical expression of neuronal exhaustion caused by sustained electrical discharges. As subtle SE may show diverse clinical features, early detection depends on clinical suspicion. Case : A 68-year-old woman was presented with repetitive involuntary movement of right limbs after two generalized tonic-clonic seizures. She experienced right middle cerebral artery infarction 4 months ago, and after the event, left side hemiplegia sustained. These seizures were first-ever after the cerebral infarction. Orientation and verbal responses were fairly preserved but general cognitive function was minimally slowed. During the video-EEG monitoring, repetitive sharp waves were noted in the right hemisphere and these sharp waves occasionally spread to the contralateral side. Her right side involuntary movement was identifiable when the epileptic discharges were found on her right hemisphere. Conclusion : We suggested that this unexpected convulsive movement is a reflection of earlier exhaustion in the right hemisphere or deefferentation of right hemisphere because of preexisting neuronal damage.

• Clinical and Experimental Pediatrics
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• v.53 no.11
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• pp.931-935
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• 2010

Juvenile idiopathic arthritis (JIA) is comprised of a heterogeneous group of several disease subtypes that are characterized by the onset of arthritis before the age of 16 years and has symptoms lasting at least 6 weeks. The previous classification of JIA included seven different categories, whereas its current classification was compiled by the International League of the Association for Rheumatology, and replaced the previous terms of "juvenile chronic arthritis" and "juvenile rheumatoid arthritis," which were used in Europe or North America, respectively, with the single nomenclature of JIA. As mentioned above, JIA is defined as arthritis of unknown etiology that manifests itself before the age of 16 years and persists for at least 6 weeks, while excluding other known conditions. The clinical symptoms of JIA can be quite variable. Several symptoms that are characteristic of arthritis are not necessarily diagnostic of JIA and may have multiple etiologies that can be differentiated with careful examination of patient history. The disease may develop over days or sometimes weeks, thereby making the diagnosis difficult at the time of presentation. To make a clinical diagnosis of JIA, the first step is to exclude arthritis with known etiologies. Of note, late treatment due to excessive delay of diagnosis can cause severe damage to joints and other organs and impair skeletal maturation. Therefore, early detection of JIA is critical to ensure prompt treatment and to prevent long-term complications including the likelihood of disability in childhood.

• Childhood Kidney Diseases
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• v.20 no.2
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• pp.83-87
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• 2016

Congenital chloride diarrhea (CLD) is a rare autosomal recessive disease that is difficult to diagnose. CLD requires early treatment to correct electrolyte imbalance and alkalosis and to prevent severe dehydration. Renal injury is clearly associated with defective electrolyte balance induced by CLD, particularly during the first months or years of life. A 7-year-old boy was diagnosed with CLD following detection of a homozygous mutation (c.2063-1G>T) in SLC26A3 at 6 months of age. During treatment with electrolyte supplements, mild proteinuria was detected at 8 months of age, and is still present. Renal biopsy showed the presence of focal renal dysplasia, with metaplastic cartilage and mononuclear cell infiltration, calcification, and fibrosis in the interstitium. Up to two-thirds of the glomeruli exhibited global obsolescence, mostly aggregated in the dysplastic area. In nondysplastic areas, the glomeruli were markedly increased in size and severely hypercellular, with increased mesangial matrix, and displayed segmental sclerosis. The marked glomerular hypertrophy with focal segmental glomerulosclerosis suggested a compensatory reaction to the severe nephron loss or glomerular obsolescence associated with renal dysplasia, with superimposed by CLD aggravating the tubulointerstitial damage.

• Toxicological Research
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• v.17
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• pp.59-69
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• 2001

Arsenic exposure is associated with several human diseases, including cancers, atherosclerosis, hypertension, and cerebrovascular diseases. In cultured cells, arsenite, an inorganic arsenic com-pound, was demonstrated to interfere with many physiological functions, such as enhancement of oxidative stress, delay of cell cycle progression, and induction of structural and numerical changes of chromosomes. The objective of this study is to investigate the effects of arsenic exposure on gene expression profiles by colorimetric cDNA microarray technique. HFW (normal human diploid skin fibroblasts), CL3 (human lung adenocarcinoma cell line), and HaCaT (immortalized human keratinocyte cell line) were treated with 5 $\mu\textrm{M}$ or 10 $\mu\textrm{M}$ sodium arsenite for 6 or 16 h, respectively. By a dual-color detection system, the expression profile of arsenite-treated cultures was compared to that of control cultures. Several genes expressed differentially were identified on the microarray membranes. For example, MDM2, SWI/SNF, ubiquitin specific protease 4, MAP3K11, RecQ protein-like 5, and Ribosomal protein Ll0a were consistently induced in all three cell types by arsenite, whereas prohibitin, cyclin D1, nucleolar protein 1, PCNA, Nm23, and immediate early protein (ETR101) were apparently inhibited. The present results suggest that arsenite insults altered the expression of several genes participating in cellular responses to DNA damage, stress, transcription, and cell cycle arrest.

• Journal of Digital Contents Society
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• v.18 no.1
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• pp.225-229
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• 2017

In this paper, various units of industrial disaster safety threats as well as local and national facilities unit real-time detection and prevention refer to the corresponding system goes into disaster management preparedness, prevention, response recovery of phase I systematic ICT skills that can be managed more efficiently. In addition, the immediate disaster prevention and preparedness for early forecasting preemptive damage scale and high-tech information exchange technology to overcome the limitations of a human disaster in the field against the analysis and strategy of preemptive disaster safety management with smart risk management and prevention in response and recovery and the scene quickly and efficient mutual cooperation and effective collaboration and cooperation of the Community Center social security presented a smart disaster safety management system.

• Journal of Korean Neurosurgical Society
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• v.47 no.1
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• pp.51-54
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• 2010

Surgery has a key role in the treatment of malignant peripheral nerve sheath tumors (MPNSTs), but the resectability of paraspinal MPNSTs is only 20%. Therefore, spinal MPNSTs show frequent recurrence and poor prognosis. Local recurrence is much more common than metastasis for MPNSTs, and surgery still has a key role in the treatment of local recurrence. Therefore, it is important that recurrence must be detected before resectability is lost. However, no evidence-based follow-up protocol has been established for MPNST. The authors performed gross total resection in a 34-year-old woman presented with thoracic MPNST. Adjuvant radiotherapy and chemotherapy were not administered since these adjuvant therapies generally do not improve survival in MPNST and may cause additional neurovascular damage. Instead, the authors monitored the primary site every 3 months using magnetic resonance imaging to detect local recurrence at the earliest opportunity. The tumor recurred locally on two occasions without overt symptoms at 21 and 24 months postoperatively. These recurrences were treated successfully by gross total removal.

• 한국방재학회:학술대회논문집
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• 2008.02a
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• pp.369-372
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• 2008

Recently, landslides have frequently occurred on natural slopes during periods of intense rainfall. With a rapidly increasing population on or near steep terrain in Korea, landslides have become one of the most significant natural hazards. Thus, it is necessary to protect people from landslides and to minimize the damage of houses, roads and other facilities. To accomplish this goal, many landslide prediction methods have been developed in the world. In this study, a simple landslide prediction system that enables people to escape the endangered area is introduced. The system is focused to debris flows which happen frequently during periods of intense rainfall. The system is based on the wireless sensor network (WSN) that is composed of sensor nodes, gateway, and server system. Sensor nodes comprising a sensing part and a communication part are developed to detect ground movement. Sensing part is designed to measure inclination angle and acceleration accurately, and communication part is deployed with Bluetooth (IEEE 802.15.1) module to transmit the data to the gateway. To verify the feasibility of this landslide prediction system, a series of experimental studies was performed at a small-scale earth slope equipped with an artificial rainfall dropping device. It is found that sensing nodes installed at slope can detect the ground motion when the slope starts to move. It is expected that the landslide prediction system by wireless senor network can provide early warnings when landslides such as debris flow occurs.