• 제목/요약/키워드: EVA1A

검색결과 145건 처리시간 0.019초

Expression Profile and Potential Roles of EVA1A in Normal and Neoplastic Pancreatic Tissues

  • Tao, Ming;Shi, Xue-Ying;Yuan, Chun-Hui;Hu, Jia;Ma, Zhao-Lai;Jiang, Bin;Xiu, Dian-Rong;Chen, Ying-Yu
    • Asian Pacific Journal of Cancer Prevention
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    • 제16권1호
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    • pp.373-376
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    • 2015
  • Background: EVA1A (eva-1 homolog A) is a novel gene that regulates programmed cell death through autophagy and apoptosis. Our objective was to investigate the expression profiles and potential role of EVA1A in normal and neoplastic human pancreatic tissues. Materials and Methods: The expression pattern of EVA1A in normal pancreatic tissue was examined by indirect immunofluorescence and confocal microscopy. Protein levels in paraffin-embedded specimens from normal and diseased pancreatic and matched non-tumor tissues were evaluated by immunohistochemistry. Results: EVA1A colocalized with glucagon but not with insulin, demonstrating production in islet alpha cells. Itwas strongly expressed in chronic pancreatitis, moderately or weakly expressed in the plasma membrane and cytoplasm in pancreatic acinar cell carcinoma, and absent in normal pancreatic acinar cells. Although the tissue architecture was deformed, EVA1A was absent in the alpha cells of pancreatic ductal adenocarcinomas, intraductal papillary mucinous neoplasms, mucinous cystadenomas, solid papillary tumors and pancreatic neuroendocrine tumors. Conclusions: EVA1A protein is specifically expressed in islet alpha cells, suggesting it may play an important role in regulating alpha-cell function. The ectopic expression of EVA1A in pancreatic neoplasms may contribute to their pathogenesis and warrants further investigation.

Characterization of Poly(ethylene-co-vinyl acetate) (EVA) Using Thermal Analytical Techniques

  • Son, Chae Eun;Choi, Sung-Seen
    • Elastomers and Composites
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    • 제54권1호
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    • pp.61-69
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    • 2019
  • Poly(ethylene-co-vinyl acetate) (EVA) is a copolymer of ethylene and vinyl acetate (VA). It is important to determine the VA content of EVA, since the properties of EVA depend highly on the VA content. EVA copolymers have been used in a wide range of applications appropriate for the different VA contents. IR, NMR, and TGA are generally used for determination of the VA content of EVA copolymers. Of these, TGA is the most reliable method and can be applied to cured EVAs. Analytical methods for determination of the VA content and properties of EVA copolymers via TGA were herein reviewed. Thermal behaviors of EVA copolymers (glass transition temperature ($T_g$), melting point ($T_m$), and crystallization temperature ($T_c$)) determined by DSC were also reviewed. Analysis of the related literature revealed that the $T_g$, $T_m$, and $T_c$ decrease by about 0.46, 1.36, and $2.08^{\circ}C$, respectively, for every 1 wt% in VA content. A method for determining the degree of crosslinking of cured EVA copolymers was also reviewed, and the degree of crosslinking tends to increase with the decrease in the VA content.

A Study of Economic Value Added Disclosures in the Annual Reports: Is EVA a Superior Measure of Corporate Performance?

  • Bhasin, Madan Lal
    • 동아시아경상학회지
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    • 제5권1호
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    • pp.10-26
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    • 2017
  • This paper explains the concept of Economic Value Added (EVA) that is gaining popularity in India. We also examine whether EVA is a superior performance measure, both for corporate disclosure and for internal governance. Of late, companies in India have started focusing on shareholders wealth creation by adopting value-based models for measuring shareholder value that helps to align managerial decision-making with the firm preferences. In recent years, the EVA framework is gradually replacing the 'traditional' measures of financial performance on account of its robustness and its immunity from 'creative' accounting. Even though some leading Indian companies have already joined the band wagon of their American counterparts in adapting the EVA-based corporate performance systems, many other are hesitating as there is no strong evidence that the EVA system works in India. Till now, EVA disclosures are "not mandatory for the Indian companies." Also, we examine the value-creation strategies of selected Indian companies by analyzing whether EVA better represents the market-value of these companies in comparison to conventional performance measures. The study indicates that "there is no strong evidence to support Stern Stewart's claim that EVA is superior to the traditional performance measures in its association with MVA." As part of this study, we have also extensively surveyed the EVA disclosures in the Annual Reports made by the same sample group of 500 corporations from India.

플라즈마 처리에 의한 EVA Foam의 표면변화 및 접착특성에 관한 연구 (Studies on the Surface Changes and Adhesion of EVA Foam by Plasma Treatment)

  • 최명진;김동호;김구니
    • 접착 및 계면
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    • 제9권1호
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    • pp.9-15
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    • 2008
  • 산소 플라즈마를 이용하여 처리시간을 다르게 하면서 EVA foam 표면의 개질을 시도하였다. EVA foam 표면 특성에 대한 플라즈마 처리 효과는 FT-IR ATR, XPS, 접촉각 측정기, SEM을 통해 연구하였으며 EVA foam의 접착특성은 박리접착강도를 측정하여 확인하였다. 플라즈마를 이용한 표면처리 결과, 유기화합물의 제거, 산소함유량의 증가, 표면의 물리적 변화 효과를 얻을 수 있었으며 EVA foam의 접착특성이 향상되었다. 플라즈마 처리 시간이 길어질수록 친수성과 EVA foam 표면의 물리적 변화가 증가하였고 각각 180초와 420초 처리에서 최대치를 나타내었다. 접착력은 420초 처리에서 최고를 나타내었으며 결과적으로 EVA foam표면의 물리적 변화가 접착력에 가장 큰 영향을 미치는 것으로 나타났다.

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마이크로캡슐의 제조와 응용 - 분산중합에 의한 core/shell 구조를 지닌 Poly(vinyl alcohol) Microsphere의 제조와 특성 - (Preparation and Application of Microcapsule - Preparation and Properties of Suspension-Polymerized Poly(vinyl alcohol) Microsphere with Core-Shell Structure -)

  • 김혜인;김효정;박수민
    • 한국염색가공학회지
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    • 제15권4호
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    • pp.65-72
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    • 2003
  • Poly(ethylene-co-vinylacetate) (EVA) microspheres were prepared by a thermally induced phase separation. Poly(vinyl Alcohol) (EVAL) microsphere with Core-Shell Structure were synthesized by a saponification on sheath of EVA microspheres. The size of EVA core/EVAL shell microsphere was decreased from $4.09\mu{m}\;to\;2.55\mu{m}$ by partial saponification of $NaOH/Na_2SO_4$/methanol(2 : 1 : 1 by weight) at $60^\circ{C}$ for 4h to produce a saponified surface layer of about 60% of original radius. In this process, the surface layer of EVAL microsphere was dissolved partially and morphology of surface was not showed. Add-on of cotton and silk printed with EVA core/EVAL shell microsphere was increased and that of printed PET was decreased. In case of EVA core/EVAL shell microsphere, Hand of cotton and silk printed was flexible and fullness.

굴 패각 분말을 함유한 항균성 복합 필름의 제조 및 특성 연구 (Preparation and Characterization of Antimicrobial Composite Film Containing Calcined Oyster Shell Powder)

  • 박기태;;서종철
    • 한국포장학회지
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    • 제27권1호
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    • pp.41-48
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    • 2021
  • 본 연구에서는 EVA/LDPE 복합소재에 OSP의 함량비를 달리한 EVA/LDPE-OSP 복합 필름을 이축압출기로 제조하였다. 제조한 복합 필름의 액티브 포장 소재로의 적용가능성을 평가하기 위해 FT-IR, DSC, TGA, OTR, WVTR, SEM, UTM 및 항균성을 분석한 결과 다음과 같은 결론을 도출하였다. EVA/LDPE-OSP 복합 필름 내 OSP 첨가는 열 안전성을 개선할 수 있었으며, OSP 함량이 높아질수록 항균성은 증가하였다. 그러나, OSP의 응집, EVA/LDPE 폴리머와 OSP 사이의 낮은 상호작용 등의 이유로 OSP의 첨가는 상대적으로 낮은 항균성과 기계적 물성, 차단특성의 저하를 확인할 수 있었다. 결론적으로 EVA/LDPE-OSP 복합 필름은 미생물에 의해 발생할 수 있는 식품의 부패를 방지하는 측면에서 긍정적인 효과를 가져올 수 있지만, 포장재로써 적용을 위해 무기입자인 OSP의 입자크기 조절, 표면처리, 상용화제 도입 등을 통한 분산성을 향상시키는 것이 필요하며 이를 통한 항균성 증진 및 필름의 물성 개선에 관한 추가 연구가 필요할 것으로 판단된다.

헥사메텔렌 디아민이 EVA/Itaconated EPDM 블렌드 발포체의 물성 및 접착강도에 미치는 영향 (I) (Effect of 1,6-Hexamethylenediamine Content on the Properties/Adhesive Strength of EVA/Itaconated EPDM Blend Foams (I))

  • 정현지;이영희;김정수;이동진;김성열
    • 한국염색가공학회지
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    • 제30권2호
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    • pp.107-116
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    • 2018
  • Simplification of the manufacturing process in shoe making is essential to improve productivity and reduce production costs. To improve the adhesion of EVA foam used as a midsole, EVA/itaconated EPDM(EPDM-g-IA)(80/20wt%) blend was prepared using Torque Rheometer-Plasti-Corder, and 1,6-hexamethylenediamine/crosslinking agent/foaming agent/additive were mixed, followed by amidation reaction and foaming to prepare EVA/EPDM-g-IA foam for shoe midsole. In this study, we investigate the effect of the content of 1,6-hexamethylenediamine(0, 0.5, 1.0, 2.0, 3.0) on the mechanical properties, water-contact angle and adhesion of EVA/itaconated EPDM foam. As the content of 1,6-hexamethylenediamine increased, mechanical properties such as tensile strength, tear strength, tensile elastic modulus, hardness, and water-contact angle were lowered, but elongation at break and compression set(%) were increased. Both normal type and non-UV type adhesive strength increased with increasing diamine content. In particular, it was found that the adhesion strength of the non-UV type adhesion increased sharply with increasing diamine content. As a result, an adherend rupture occurs in a foam sample having a content of 1,6-hexamethylenediamine of 3phr. From this, it can be seen that the EVA/itaconated EPDM foam for shoe midsoles, which can be used for non-UV adhesion without primer and UV treatments, have been developed.

EVA 완충재의 형상변환을 통한 복합구조의 바닥충격음 변이 조사 (Investigation of the level difference of floor impact noises through the shape variation of EVA resilient materials with composite floor structure)

  • 이야긴;이승민;한찬훈
    • 한국음향학회지
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    • 제43권1호
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    • pp.60-71
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    • 2024
  • 본 연구는 일반적인 평평한 에틸렌 비닐 아세테이트(Ethylen Vinyl Acetate, EVA) 완충재의 형상을 변화시켜 다양한 차음소재와 조합하여 복합구조의 바닥충격음 변화를 조사하는 데에 목적이 있다. 바닥충격음 저감에 효과적인 완충재를 선정하기 위해 Flat, Deck, Cavity type의 EVA, EPS, PET 흡음재, PP판넬, 고무발판 등 다양한 완충재를 조합하여 뱅머신을 이용한 1차 실험을 진행하였다. 1차 실험 데이터에 대해 통계분석한 결과 완충재 두께가 40 mm에 가까울수록 바닥충격음 저감효과가 증가하였으며 PET 흡음재, PP시트, 고무발판 등을 조합한 복합완충재에서 바닥충격음 효과가 증가하는 것을 알 수 있었다. 이에따라 2차 실험에서 모든 복합완충재의 두께는 40 mm로 통일하였으며, 1차 실험에 사용된 Flat, Deck, Cavity type 및 EVA를 발판형태로 가공한 Mount type 등 4가지 형태의 복합완충재를 설계하였다. 또한, Mount type을 제외한 3가지 기본 형태에서 각각 PET 흡음재(7 mm)를 추가했을 시 바닥충격음 변화를 살펴보았으며, Mount type의 경우 EVA발판 개수에 따른 바닥충격음 변화에 대해 고무공 충격원을 이용한 2차 실험을 진행하였다. 모든 실험은 공인인증시험기관의 목업실험실에서 진행하였다. 실험 결과, 기본형태의 Flat, Deck, Cavity type에서 PET를 추가할 경우 통계적으로 경량 5 dB ~ 9 dB, 중량 1 dB ~ 5 dB의 저감효과가 나타난 것을 알 수 있었다. 특히, Mount type의 경우 발판 수가 36개 이상일 때 경량 및 중량충격음에서 우수한 것으로 나타났다. 또한, 4가지 기본형태에 따라 동탄성계수가 높아질수록 바닥충격음의 저감이 증가하는 것으로 나타났다.

기업재무구조에의한 경제적 부가가치 분석 (The EVA Analysis by the Financial Structure of the Firm)

  • 윤석곤
    • 한국컴퓨터정보학회논문지
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    • 제4권2호
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    • pp.155-163
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    • 1999
  • This study is intended to analyze what trend the EVA technique recently actively studied shows according to the financial structure of the firm. As a result of analysis, it was found that the firm with the entire sum of its capitals depleted showed the negative value in both the EVA on the basis of operating profit and the EVA on the basis of cash flow from 5 years before its capitals were depleted. Especially, its EVA showed the negative value more strongly than the cash flow accruing by business activity. In analyzing the EVA of the firm with more than 1,500% of the debt to equity ratio, its EVA also showed the negative value from 5 years ago. But the firm with the good financial structure of the debt to equity of less than 35% showed the positive value in the EVA on the basis of its cash flow from 5 years ago. As can be seen from this result, the fact is that the firm can survive only when it raises its EVA through its structural change(re-engineering) and business innovation. Therefore, firms need to seek to turn their business philosophy or policy into the promotion of business innovation and business management emphasizing technology in order to improve their EVA indicators.

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용매 처리에 의한 EVA foam 표면 특성에 관한 연구 (Studies on the Characteristics of EVA Foam by Solvent Treatment)

  • 천제환;김구니;홍순영;유종선;오상택
    • 접착 및 계면
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    • 제2권3호
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    • pp.9-15
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    • 2001
  • 표면 에너지가 낮아 접착이 어려운 EVA foam을 용해도 파라미터와 표면장력이 다른 용매로 표면처리하여 표면의 상태 변화를 SEM, 접촉각 측정 등으로 조사하였으며 표면의 변화가 접착력에 미치는 영향을 고찰하였다. Zismann plot에 의해 계산된 EVA foam의 임계표면장력 (${\gamma}_{c,0}$)은 27.08 dyne/cm이었다. 용매 처리에 의해 EVA foam 표면의 형태 및 임계포면장력이 변화하였으며 EVA foam의 팽윤도가 용해도 파라미터에 의해 영향을 받는 것에 비해 표면의 변화 정도는 용매의 표면장력에 더 크게 의존하였다. 표면의 변화는 용매의 표면장력 (${\gamma}_L$)이 EVA foam의 임계표면장력 보다 낮아 wetting이 잘될수록 커지는 것으로 나타났다. 용매 처리된 EVA foam을 접착한 결과 처리하지 않은 것에 비해 접착력이 600% 이상 크게 향상되었으며, ${\gamma}_c$가 프라이머의 ${\gamma}_{L,p}$에 근접하여 ${\gamma}_c/{\gamma}_{L,p}$가 1에 가까워질수록 접착력이 증가하였다.

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