• Asian-Australasian Journal of Animal Sciences
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• 제16권3호
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• pp.425-429
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• 2003

Staphylococcus aureus is a major pathogen for cattle, causing various forms of subclinical and clinical mastitis and could be a causative agent of food poisoning, it produces various superantigenic exotoxins which have a great public health significance. A total of 72 S. aureus clinical isolates from dairy farms located in Kyunggi Province Korea were examined for the species identification by biochemical method, and for the detection of $\beta$-lactamase, enterotoxin and other exotoxins genes by PCR. The results of species identification by biochemical method agreed with those of PCR done with species specific primer STA-AU. $\beta$-lactamase is an enzyme closely associated with the resistance to antibiotic penicillin, which is an important means of treatment of mastitis, all the isolates were positive for the presence of genes encoding $\beta$-lactamase, which were reproduced in penicillin susceptibility disc assay. Six types of toxin genes, Staphylococcal enterotoxin (SE)A, SEB, SEC, SEE, toxic shock syndrome toxin (TSST-1) and exfoliative toxin A (ET A) were detected in 72 isolates by PCR associated genotypic method in this study, none of the isolates carried the genes for enterotoxin D (SED) and exfoliative toxin B (ETB). The occurrence rate of exotoxin genes rated as 12.5%, and the precision of the PCR identification results has been confirmed using the reference strains.

• 대한원격탐사학회지
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• 제36권4호
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• pp.645-652
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• 2020

GK2A(GEO-KOMPSAT-2A)satellite has been operating excellently since its launch in Dec 2018. The secondary payload called KSEM (Korean Space Environment Monitor) was equipped into the GK2A satellite along with AMI (Advanced Meteorological Imager) sensor. KSEM is the Korea's first operational geostationary space weather sensor and has been developed collaboratively by KHU (Kyung Hee University) and KARI (Korea Aerospace Research Institute). The interface works between KSEM and GK2A were conducted by KARI. Various interface tests, which aim for evaluating effective functionality of KSEM with the spacecraft, were intensively conducted at KARI facilities. Main tests consisted of mechanical and electrical check-up activities between the KSEM and GK2A. Interface tests of KSEM, which involve pre-launch tests such as ETB and GK2A system level tests, were conducted to evaluate functional and performance of KSEM before the launch. The tests carried out during the GK2A LEOP (Launch and Early Orbit Phase) and IOT (In Orbit Test) period (Dec 2018 ~ June 2019) showed excellent in-orbit performance of KSEM data.

• Preventive Nutrition and Food Science
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• 제9권3호
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• pp.245-252
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• 2004

This study investigated the effects of an ethanol extract of Allium monanthum MAX. (AME) on ethanol-induced hepatotoxicity in rat liver. Sprague-Dawley rats weighing 100～150 g, were divided into 5 groups; normal group (NOR), AME 200 mg/kg treated group (S1), ethanol (35%, 10 mL/kg) treated group (S2), AME 200 mg/kg and ethanol (35%, 10 mL/kg) treated group (S3) and AME 400 mg/kg and alcohol (35%, 10 mL/kg) treated group (S4). AME was fractionated by the following solvents: n-hexane, chloroform, EtOAC and n-BuOH. Antioxidant index of the n-BuOH fraction was 600 ppm, highest among fractions. The growth rate and feed efficiency ratio were decreased by ethanol, but gradually increased to the corresponding level of the normal group by administering AME. The serum ALT activities that were elevated by ethanol were significantly decreased by AME administration. It was also observed that the hepatic activities of SOD, catalase, xanthine oxidase and GSH-Px that were increased by ethanol were also markedly decreased in the AME treated group with compared to ETB. These results suggest that ethanol extracts of Allium monanthum MAX. may have a protective effect on ethanol-induced hepatotoxicity in rat liver.

• 한국항공우주학회지
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• 제45권7호
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• pp.594-599
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• 2017

본 논문에서는 GK2 위성의 최종 조립시험단계의 극성시험 과정에서 태양센서에 전기자극을 주어 자세오차를 다양하게 모사하는 지상시험장치(Test-aid)의 개발과 검증에 관한 내용을 정리한다. 본 논문에서 GK2 위성에 사용되는 태양센서 Test-aid는 2축 아날로그 태양센서를 대상으로 시험하는 것으로 고장으로 인한 백업을 고려하여 Test-aid의 국산화를 진행하였다. 또한, 시험을 통해 천리안위성에 사용되었던 Test-aid 특성과 국내업체를 통해 제작된 Test-aid의 특성이 기존 장비를 대체할 수 있음을 확인하였다. 본 논문에서 소개하는 국내 제작된 Test-aid는 기존의 천리안위성에 사용되었던 Test-aid와 달리 차이점이 생길시 제어기의 튜닝 기능을 이용하여 기존장비와 동일한 성능을 구사할 수 있음을 보였다.

• 대한화장품학회지
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• 제24권3호
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• pp.134-145
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• 1998

Facial hyperpigmentation in women, which is considered to be a serious cosmetic disability and a cause of mental distress, requires proper management. Melanocyte dendricity is a crucial factor affecting epidermal pigmentation. We found that BQ-788, the endothelin-B (ETB) receptor antagonist, blocks the formation of multi-dendricity which is induced by cocultured keratinocytes. Melanocytes in vivo show numerous dendrites which are in close contact with multiple keratinocytes, forming the epidermal-melanin unit. While melanocytes transfer their melanosomes into the neighboring keratinocytes via dendrites, keratinocytes secrete many growth factors and cytokines that influence viability, morphology, and melanin formation of melanocytes. Endothelin-1 (ET-1), prostaglandin E2(PGE2), and leukotriene-C4 (LT-C4) have been suggested as the candidates for increasing dendricity. Other reports suggested that ET-1 has stimulatory effects on proliferation and melanin formation of melanocytes in vitro. In the present study, using type-specific ET receptor antagonists, we observed how the morphology of melanocytes could be modulated in a coculture system. In addition, the roles of ET-1 for morphology and proliferation on melanocytes were evaluated in different culture media. We suggest that ET-1 increases dendricity and proliferation of melanocytes, and that its dendrite-inducing effect and mitogenic effect are regulated independently.

• 한국우주과학회:학술대회논문집(한국우주과학회보)
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• 한국우주과학회 2009년도 한국우주과학회보 제18권2호
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• pp.28.3-28.3
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• 2009

과학기술위성 3호는 2007년 6월에 사업착수를 시작하여, 동년 8월 시스템요구사항검토회의(SRR)를 통해 임무 요구사항을 도출하였고, 동년 12월에 시스템기본설계검토회의(SDR)과 2008년 9월 시스템예비설계검토회의(PDR)를 개최하여 시험인증모델(EQM, Engineering& Qualification Model) 제작을 시작하여, 납품을 완료하고 ETB(Engineering Test Bed)상에서 유닛의 기능 시험 및 접속시험, 그리고 환경시험을 수행을 완료하였다. 또한 열구조모델 (STM, Structure and Thermal Model)도 제작을 완료하고 발사환경시험과 열평형 환경시험을 완료하였다. 이와같이 시험인증모델 및 열구조모델에 대한 지상에서의 시험과 검증이 완료된 시험결과를 바탕으로 2009년 9월 상세설계를 완료하고 비행모델 제작에 착수할 예정이다. 이 논문에서는 과학기술위성 3호의 시험인증모델에 대한 시험의 목적, 종류 그리고 검증에 대한 결과 그리고 향후 계획에 대해 발표하고자 한다. 참고로 과학기술위성 3호는 주탑재체인 다목적적외선영상시스템(MIRIS)은 우리 은하계의 근적외선 관측, 우주 배경복사 관측 및 지구 지표면의 적외선 영상 획득을 임무로 하고 있고, 부탑재체인 초소형 영상 분광기(COMIS)는 한반도 지역의 다중 스펙트럼 영상을 획득함으로써 대기관측 및 환경감시의 임무를 가지고 있다.

• 한국정보과학회논문지:시스템및이론
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• 제36권1호
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• pp.9-20
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• 2009

마감시간이 있는 주기 태스크와 마감시간이 없는 비주기 태스크가 공존하는 결성 실시간 시스템에서는 주기 태스크의 마감시간과 비주기 태스크의 빠른 응답시간을 보장하는 것이 중요하다. 본 논문에서는 비주기 태스크 처리에 효율적이면서 잘 알려져 있는 알고리즘인 Total Bandwidth Server(TBS) 보다 향상된 알고리즘인 Enhanced TBS(ETBS)를 제시한다. ETBS는 Earliest Deadline First(EDF) 스케줄링 알고리즘을 사용하는 단일처리기 시스템에서 주기 작업의 단위 수행시간마다 확보할 수 있는 잉여 여유시간을 이용해 온라인으로 비주기 태스크에 마감시간을 부여하는 알고리즘이다. 제시한 알고리즘은 주기 및 비주기 태스크들이 처리기의 이용률을 모두 이용할 수 있게 하며 주어진 주기 태스크들의 마감시간을 보장한다. ETBS 알고리즘은 TBS와 같은 계산 복잡도 O(1)을 가지면서도 TBS보다 좋은 응답시간을 가짐을 이론적으로 보였고, 정량적인 응답시간 차이는 모의실험을 통해 보였다.

• 한국동물위생학회지
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• 제45권3호
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• pp.171-180
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• 2022

The aim of this study was to investigate the prevalence of antimicrobial resistance and virulence factors in staphylococci isolated from canine otitis externa. A total 295 causative microorganisms were isolated. The most common isolated species were Staphylococcus (S) pseudintermedius (94 isolates) followed by Pseudomonas aeruginosa (60 isolates), S. schleiferi (25 isolates), Escherichia coli (23 isolates) and Proteus mirabilis (20 isolates). Staphylococci isolates were showed high resistance to penicillin (78.6%), erythromycin (55.9%), tetracycline (52.4%), clindamycin (51.7%) and ciprofloxacin (42.8%). Of the 145 staphylococci isolates, 49 (33.8%) methicillin-resistant staphylococci (MRS) were observed, distributed among S. pseudintermedius (n=34), S. schleiferi (n=6), S. epidermis (n=4), S. hominis (n=2), S. aureus, S. caprae and S. saprophyticus (n=1, respectively). Forty-three (87.8%) of 49 MRS and 10 (10.4%) of 96 methicillin-susceptibility staphylococci harbored mecA gene. About 80% of MRS were multidrug-resistant with resistance to at least one antibiotic in three or more antibiotic classes. Resistance genes blaZ (93/114, 81.5%), ermB (35/81, 43.2%), ermC (3/81, 3.7%), aacA-aphD (50/54, 92.5%), tetM (69/76, 90.7%) and tetK (6/76, 7.8%) were detected among resistant isolates. Virulence factors genes lukF and lukS were found in 100%(145/145) and 43.4%(63/145), respectively. Genes encoding ermA, eta, etb and tsst were not detected. To the best of our knowledge, this is the first study which investigated for the presence of genes encoding antimicrobial resistance and staphylococcal toxins in staphylococci isolated from canine otitis externa. A continuous monitoring and surveillance program to prevent antimicrobial resistance in companion animals is demanded.

• 한국식품저장유통학회지
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• 제11권1호
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• pp.79-87
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• 2004

감잎 phenolic compounds가 횐쥐에서 에탄올투여로 생성된 oxygen free radical대사와 각종 효소활성에 미치는 영향을 검토하기 위하여 실험동물을 정상군, 감잎 phenolic compounds 투여군(70 mg/kg), 에탄을 단독투여군, 에탄올과 감잎 phenolic compounds 소량 병합투여군(70 mg/kg), 에탄올과 감잎 phenolic compounds 대량 병합투여군(140 mg/kg)의 5군으로 나누어 6주간 사육하여 체중증가율, 식이효율 및 혈청중 ALT, ALP 및 LDH활성 측정과 간손상 억제효과를 검토하기 위하여 간조직중 유리기 생성계 효소인 XO활성, 유리기 해독계 효소인 SOD, calaase 및 GSH-Px활성과 지질과산화물인 TBARS 및 GSH함량을 측정한 결과는 다음과 같다. 각 분획의 항산화력은 EtOAC, n-BuOH, chloroform, n-hexane, water 분획순으로 EtOAC분획의 항산화력이 가장 우수하였다. 에탄올만을 투여한 군은 정상군에 비하여 체중증가율과 식이효율이 유의적으로 감소되었고 감잎 phenolic compounds를 병합투여한 군은 체중증가율과 식이효율이 정상군에 근접하게 상승되었다. 간 손상의 지표로 알려진 ALT, ALP 및 LDH활성은 에탄올투여로 정상군에 비하여 유의하게 증가되었으나 감잎 phenolic compounds를 투여하여 Elf에 비하여 많은 감소를 보였다. 간조직중 유리기 생성계 효소인 XO활성은 에탄올투여로 정상군에 비하여 큰 폭의 증가를 보였으나 본 실험기간내에서는 유의성 있는 변화는 아니었으며 감잎 phenolic compounds를 투여하여 에탄올투여로 증가된 효소활성이 ETB에 비하여 감소는 되었으나 유의한 변화는 아니었다. 유리기 해독계 효소인 SOD, catalase 및 GSH-Px 활성은 에탄올투여로 정상군에 비하여 크게 증가되었으나 감잎 phenolic compounds투여로 ETB에 비하여 뚜렷한 저하효과를 나타냈다. TBA반응성생산물량에서 에탄올투여로 과산화지질함량이 CON에 비하여 많이 증가되어 유의한 변화를 나타냈으나 감잎phenolic compounds는 에탄올투여로 증가된 함량을 ETH에 비하여 1/3∼$\frac{1}{2}$정도 용량의존적으로 감소시켰으며 PEI의 경우 그 함량이 CON보다 오히려 낮았다. 또한 에탄올투여로 감소된 간조직중 GSH함량은 감잎 phenolic compounds 투여로 정상군보다 증가되었다. 이상의 실험결과 에서 감잎 phenolic compounds가 에탄올투여로 증가된 유리기 해독계 효소인 GSH-Px활성을 큰 폭으로 감소시키고 에탄올투여로 감소된 비효소적 항산화작용을 나타내는 GSH함량을 다량 증가시킴으로서 지질과산화물에 대한 방어력이 증가되어 나타난 결과로 여겨지며, 또한 혈청중의 ALT, ALP 및 LDH활성을 유의성있게 감소시키므로서 감잎 phenolic compounds가 에탄올에 의한 간세포 손상에 대한 해독 및 보호작용이 있는 것으로 사료된다.

• Journal of Ecology and Environment
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• 제43권2호
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• pp.85-97
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• 2019

Background: Despite the increasing role of dry forests in climate change adaptation and mitigation, these versatile resources has got less attention in the national and regional planning, their potential to enhance the local and national economy has been overlooked, and their contribution to sustainable environmental management has not been recognized. Hence, the objective of this study was to assess the socioeconomic contribution of dry forests and forest products to climate change adaptation in the Liben Woreda, Southern Oromia region of Ethiopia. Methods: For this study, an integrated qualitative and quantitative approach was used. A total of 74 households from villages in the Bulbul, Boba, and Melka-Guba kebeles were randomly selected for the household survey. Results: Results showed that 75% of the respondents in the area indicated that climate change has become their major sources of vulnerability, where drought has been manifested in the form of crops failure and massive death of livestock particularly cattle species. The main income strategies of the study households include livestock, crop, forests such as gum and resins, firewood and charcoal and non-farm activities such as in the form of petty trade, wage and aid. The average total household income was ETB 11,209.7. Out of this, dry forest income constituted 15% of the total income. In addition to using dry forests as rangeland for livestock, the communities collect wood for construction, fodder, traditional medicine, and forest food both for subsistence and for sale. On the other hand, dry forest products could be considered as less vulnerable, rather resilient livelihood strategies to climate- and environment-related risks compared to livestock and crop production such as in the face of drought periods. More than 48.6% of the households argued that the income generated from dry forests increased substantially due to increment in the level of engagement of family members in forest based income activities. On the other hand, 35.8% of the households responded that livestock production, particularly camels and goats, have been making the livelihood strategies of the respondents more resilient indicating the shift made from grazers browsers to livestock. In general trends show that, the trends of livelihood dependency on dry forest were highly increasing indicating the importance of dry forest income in responsse to frequent droughts. Conclusions: Dry forest income has been becoming crucial livelihood staretgy in response to frequent droughts in the study area and hence, it is important to improve the management of dry forests for livelihood enhancement, while also securing their long-term ecological functions.