• Korean Journal of Radiology
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• v.20 no.1
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• pp.102-113
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• 2019

Objective: To assess the accuracy and potential bias of computed tomography (CT) ventricular volumetry using semiautomatic three-dimensional (3D) threshold-based segmentation in repaired tetralogy of Fallot, and to compare them to those of two-dimensional (2D) magnetic resonance imaging (MRI). Materials and Methods: This retrospective study evaluated 32 patients with repaired tetralogy of Fallot who had undergone both cardiac CT and MRI within 3 years. For ventricular volumetry, semiautomatic 3D threshold-based segmentation was used in CT, while a manual simplified contouring 2D method was used in MRI. The indexed ventricular volumes were compared between CT and MRI. The indexed ventricular stroke volumes were compared with the indexed arterial stroke volumes measured using phase-contrast MRI. The mean differences and degrees of agreement in the indexed ventricular and stroke volumes were evaluated using Bland-Altman analysis. Results: The indexed end-systolic (ES) volumes showed no significant difference between CT and MRI (p > 0.05), while the indexed end-diastolic (ED) volumes were significantly larger on CT than on MRI (93.6 ± 17.5 mL/m² vs. 87.3 ± 15.5 mL/m² for the left ventricle [p < 0.001] and 177.2 ± 39.5 mL/m² vs. 161.7 ± 33.1 mL/m² for the right ventricle [p < 0.001], respectively). The mean differences between CT and MRI were smaller for the indexed ES volumes (2.0-2.5 mL/m²) than for the indexed ED volumes (6.3-15.5 mL/m²). CT overestimated the stroke volumes by 14-16%. With phase-contrast MRI as a reference, CT (7.2-14.3 mL/m²) showed greater mean differences in the indexed stroke volumes than did MRI (0.8-3.3 mL/m²; p < 0.005). Conclusion: Compared to 2D MRI, CT ventricular volumetry using semiautomatic 3D threshold-based segmentation provides comparable ES volumes, but overestimates the ED and stroke volumes in patients with repaired tetralogy of Fallot.

• Journal of Embryo Transfer
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• v.32 no.1
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• pp.25-31
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• 2017

This study was conducted to investigate the effect of activation method on the endoplasmic reticulum (ER) stress induction, apoptosis and in vitro development of porcine parthenogenetic embryos. Porcine in vitro matured oocytes were activated by four activation methods; 1) electric stimulus (ES) (E), 2) $ES+10{\mu}M$ Ca-ionophore (A23187) treatment (EC), 3) ES+2 mM 6-dimethylaminopurine (6-DMAP) treatment (ED), or 4) ES+A23187 and 6-DMAP treatments (ECD). Parthenogenetic embryos were sampled to analyze x-box binding protein 1 (Xbp1) mRNA, ER stress-associated genes and apoptosis genes at 3 h after ES and the 1-cell and blastocyst stages. In the EC group, the band intensity of spliced Xbp1 (Xbp1s) mRNA was higher than those of the other groups at the 3 h and 1-cell stage, and higher than that of the E group at the blastocyst stage. Four ER stress-associated genes were expressed at the highest level in the EC group and weakly expressed in the ED group at 3 h after activation. However, most of the genes were highly expressed at the 1-cell and blastocyst stages with some variation in the EC and ECD groups. Expression of Bcl-2-associated X protein (Bax) and caspase-3 mRNA was significantly higher in the EC group than in the other groups at all development stages. The developmental rates to the blastocyst stage were higher in the ED and ECD groups than in the E and EC groups. These results suggest that the intracellular ER stress of parthenogenetic porcine embryos is affected by the activation method and subsequently lead to the apoptosis of embryos.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2013.05a
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• pp.91-92
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• 2013

• Journal of the Korea Institute of Information and Communication Engineering
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• v.19 no.3
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• pp.697-707
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• 2015

This paper covered the design and implementation of the demodulation receiver in the ADS-B 1090ES system, which is one of the CNS/ATM's surveillance systems. This researched demodulation performed at the level required by RTCA DO-268B and EUROCAE ED-129. The single signal process method, which applies a baseline multi-sample technique among multi-amplitude sample demodulations, was suggested to improve the quality of the receiver signal, the dynamic range and so on. The suggested multi-signal level tuning method has enhanced the single-signal process method, reducing the unstable reception ratio by the transmit output level difference and manufacturing receiver hardware. The result was that the receiver suggested by the method had 0~87dBm in dynamic range and -90dBm in MTL. This shows a better performance by -3dBm less than the international standard in ADS-B 1090ES ground receiver equipment. The systems which use a similar modulation method, will be considered to be widely applied.

• Journal of the Institute of Electronics Engineers of Korea SC
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• v.38 no.5
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• pp.59-69
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• 2001

Recently many researches concerning heart sound analysis are being processed with development of digital signal processing and electronic components. But there are few researches about recognition of heart sound, especially full cardiac cycled heart sound, In this paper, a new recognition methods about. full cardiac cycled heart sound was proposed. For the first, the database was built by principal components analysis on training heart sound set. This database is used to recognize new input of heart sound, Ilear sounds were classified into seven classes such as normal(NO) class, pre-systolic murmurr(PS) class, early systolic murmur(ES) class, late systolic murmurr(LS) class, early diastolic murmur(EI) class, late diastolic murmur(LD) class and continuous murmuru(CM) class. As a result, we could verify that our new method has better efficiencies for the recognition the characteristics of heart sound than any precedent research. The maximum recognition rates of the new method are 71% for NO, 80% for PS and ES, 78% for LS, 87% for ED, 60% for LD and 20% for CM. Although the present results aren't practically sufficient to use our new method in recognizing heart sound, the importance of this paper is for recognition of heart sound within full cardiac cycle. We can get a better result by building a more efficient database.

• Journal of Veterinary Clinics
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• v.29 no.1
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• pp.27-32
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• 2012

The purpose of this study was to evaluate survival rates of vitrified mouse blastocysts in various vitrification solutions (cryoprotectants) and apparatuses. The mouse blastocysts were harvested from culture of mouse 2 cell embryo and were divided into three group (i) untreated (control); (ii) exposed to cryoprotectant agents; or (iii) cryopreserved by various vitrification apparatuses. Vitrification solutions are 40% ethylene glycol (EG) + 5.8 mg/mL ficoll + 0.5M sucrose (EFS solution), 3M glycerol + 3M EG (ES solution), 20% EG + 20% dimethyl sulfoxide (ED solution), 3M EG + 1.0 m sucrose (ES solution). Vitrification apparatuses consisted of 5 groups ; closed plastic straw (CPS), electron microscope (EM) grid, cryoloop, open pulled straw (OPS), and glass micropippete in plastic straw (GPS). The survival rates of control were 88.0%. The survival rates of exposed blastocysts in EFS, GE, ED, and ES solutions were 70.8%, 43.5% (P<0.01), 83.3% and 65.2%, respectively. The survival rates of vitrified blastocysts in CPS, EM grid, cryoloop, OPS and GPS were 56.5% (P< 0.01), 72.7%, 83.3%, 60.9% (P<0.05) and 54.2% (P<0.01), respectively. Among the vitrification solutions, the highest survival rate was seen in blastocysts vitrified in EG + DMSO (83.3%). The survival rate was not significantly different from that of the control (88%). Blastocysts cryopreserved with glycerol in all groups had an overall low survival rate of 43.5%. Survival rate of mouse blastocysts between vitrification apparatuses showed higher in cryoloop.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2014.10a
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• pp.189-192
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• 2014

Recently, U.S. and Europe, which are advanced to Air Traffic Control Management, are interest in replacing Radar System with Communications, Navigation and Surveillance(CNS) and Air Traffic Management(ATM). They pursue to research the efficient Air Traffic Control Management. This paper covers ADS-B 1090ES system which is one of CNS/ATM surveillance systems. This research satisfied all performance required by RTCA DO-268B and EUROCAE ED-129. It optimized algorism to mainly enhance performance such as quality of receiver signal, dynamic range, and so on. The optimized mechanism provided stable performance of demodulation, tuned the level of signal, and had reduced the false reception ratio by the signal level difference. The analyzed algorism helped great performance and will be considered to apply broad system applications.

• Proceedings of the Korea Water Resources Association Conference
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• 2018.05a
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• pp.107-107
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• 2018

기후 변화가 심해짐에 따라 한반도의 기후 또한 온대에서 아열대로 변화하고 있다. 기후대가 변하게 되면 수문학적 순환 및 식생의 분포 또한 달라지게 된다. 식생의 분포는 결국 토지 이용을 의미하며, 서로 다른 토지 이용은 대기와의 상호작용을 통해 각기 다른 반응을 보이게 된다. 본 연구에서는 기후대가 가장 빠르게 변화하고 있는 제주도를 대상으로 기후 변화 및 토지 이용 변화에 따른 생태수문학적 영향을 Ecosystem Demography Model version 2.2(ED-2.2) 모형을 사용하여 살펴 본다. 제주도의 플럭스 타워 및 산림 조사 자료를 활용하여 ED-2.2 모형을 검증하였다. CRU-NCEP 기상자료 및 Land-Use Harmonization (LUH) 토지이용자료를 활용하여 과거기간(1500~2015)의 잠재 식생 및 실제 식생 상태를 산정하고 그 차이를 분석하였다. 산정된 최종 실제 식생 상태를 바탕으로 기후 및 토지이용 시나리오(RCP 3.0 및 6.0)를 적용하고, 다양한 전지구모형(GFDL-ESM2M, HadGEM2-ES, IPSL-CM5A-LR, MIROC5)의 기상자료에 따라 물 순환, 탄소 순환 및 식생의 분포가 어떻게 달라지는 지 분석한다.

• Journal of Magnetics
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• v.17 no.3
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• pp.229-232
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• 2012

This study examined the correlation between MR cine and myocardium Single-photon emission computed tomography (SPECT) by comparing the measured cardiac ejection fractions. The usefulness of cardiac MRI was also evaluated. Ten patients (8 men, 2 women and average age of 58.6 years), who underwent a myocardium SPECT scan and cardiac cine MRI scan among patients who visited the hospital for the chief complaint of cardiac disorder from June 1, 2010 to February 10, 2011, were enrolled in this study. The cardiac ejection fraction was calculated from the images obtained in both scans. The data was used to examine the correlation. The regression equation the cardiac ejection fraction values of the 10 patients obtained in myocardium SPECT and MRI cine was Y = 1.12X-8.91 ($R^2$ = 0.78, significance of F = 0.001639, and confidence level of 95%). The results were significant when the cardiac ejection fraction obtained from MRI cine was compared with that obtained from myocardium SPECT. Overall, a cardiac examination using MRI enables an investigation of not only the ejection fraction but also the ED and ES volumes, stroke volume, wall thickness, and wall thickening in a higher spatial resolution despite the examination being conducted once. This examination is believed to be very useful for diagnosing patients with cardiac disease.

• Proceedings of the Korean Vacuum Society Conference
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• 1999.07a
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• pp.187-187
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• 1999

fcc(110) 표면이나 bcc(110) 표면과 같이 2-fold 대칭성을 갖는 표면 위에 초미세 박막을 성장시킬 경우 토대표면의 두 방향에 대한 비 대칭성으로 흡착물이 비대칭적인 cluster 형태로 성장되는 것이 보고되고 있다. 최근 STM에 의한 Ps(110) 표면 위에나 Si(100) 또는 W(110) 표면 위에 성장 실험은 흡착물이 길게 늘어선 한 줄 형태의 성장 또는 가로 세로가 비대칭적인 cluster 형태로 성장되는 것을 보고하고 있고, 이러한 특정 형태의 성장의 원인으로 흡착 원자의 방향에 따른 분산 속도의 비대칭성, 인접 원자와의 비대칭적인 상호작용, 또는 cluster 경계 방향의 분산 속도 등을 들고 있다. 그러나 아직 대부분의 물질계에 비해 흡착원자의 분산속도 또는 분산 장벽에 대해서는 잘 알려져 있지 않다. 원하는 원자 단위 구조물 제작을 위해서는 흡착물의 분산속도에 대한 이해가 필수적이며, 본 연구는 KMC 시뮬레이션과 실험 결과를 비교하는 방법을 통하여 위치와 조건에 따른 각각의 분산 속도를 구하고자 하는 시도이다. 특히 비대칭적 토대 위에서의 나타나는 다양한 형태의 미시적 성장구조에 관심을 가지며, 연구 방법으로는 KMC 시뮬레이션을 이용한다. 미시적 성장 양식은 분산 장벽 형태에 의해 크게 결정된다. 분산장벽 중에서 성장에 비교적 큰 영향을 미치는 것으로는 테라스 위의 원자가 이동할 때의 분산장벽인 Ed, 계단 끝에 부착된 원자가 분리될 때의 장벽인 Ep, 그리고 위 테라스에서 계단 아래로 떨어져 내려갈 때 만나는 Schwoebel 장벽들이 있다. 먼저 대칭적인 fcc(100) 표면 위에서의 성장 구조를 정리해보면 분산 장벽에 따라 다양한 미시적 성장형태를 볼 수 있었다. 다층 성장의 경우도 그 양식은 sub-ML 성장과 동일한 형태를 가지므로 sub-ML 성장구조로 전체 성장 양식을 예견할 수 있다. 일반적인 경향은 Ep가 커질수록 fractal 성장형태가 되며, Ed가 적을수록 cluster 밀도가 작아지나, 같은 Ed+Ep에 대해서는 동일한 크기의 팔 넓이(수평 수직 방향 cluster 두께)를 가진다. 따라서 실험으로부터 얻은 cluster의 팔 넓이로부터 Ed+Ep 값을 결정할 수 있고, cluster 밀도와 fractal 차원으로부터 각각 Ed와 Ep값을 분리하여 얻을 수 있다. 또한 다층 성장에 대한 거칠기(roughness) 값으로부터 Es값도 구할 수 있다. 양방향 대칭성을 갖지 않은 fcc(110) 표면과 같은 경우, 형태는 다양하지만 동일한 방법으로 추정이 가능하다. (110) 표면의 경우 nearest neighbor 원자가 한 축으로 형성되고 따라서 이 축과 이것과 수직인 축에 대한 상호작용이나 분산 장벽 모두가 비대칭적이다. 따라서 분산 장벽도 x-축, y-축 방향에 따라 분리하여 Edx, E요, Epx, Epy 등과 같이 방향에 따라 다르게 고려해야 한다. 이러한 비대칭적인 분산 장벽을 고려하여 KMC 시뮬레이션을 수행하면 수평축과 수직축의 분산 장벽의 비에 따라 cluster의 두께비가 달라지는 성장을 볼 수 있었고, 한 축 방향으로의 팔 넓이는 fcc(100) 표면의 경우 동일한 Ed+Ep값에 대응하는 팔 넓이와 거의 동일한 결과가 나타나는 것을 볼 수 있다. 따라서 이러한 비대칭적인 모양을 가지는 성장의 경우도 cluster 밀도, cluster 모양, cluster의 양 축 방향 길이 비, 양 축 방향의 평균 팔 넓이로부터 각 축 방향의 분산 장벽을 얻어낼 수 있을 것으로 보인다.