• 한국생명과학회:학술대회논문집
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• 한국생명과학회 2006년도 제47회 학술심포지움 및 추계국제학술대회
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• pp.69.1-69.1
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• 2006

• Molecules and Cells
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• 제25권1호
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• pp.142-147
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• 2008

We recently used degenerate PCR and locus-specific PCR methods to identify the endogenous retroviruses (ERV) in the bovine genome. Using the ovine ERV classification system, the bovine ERVs (BERVs) could be classified into four families. Here, we searched the most recently released bovine genome database with the partial nucleotide sequence of the pro/pol region of the BERV ${\beta}3$ family. This allowed us to obtain and analyze the complete genome of BERV ${\beta}3$. The BERV ${\beta}3$ genome is 7666 nucleotides long and has the typical retroviral organization, namely, 5'-long terminal repeat (LTR)-gag-pro-pol-env-LTR-3'. The deduced open reading frames for gag, pro, pol and env of BERV ${\beta}3$ en- code 507, 271, 879 and 603 amino acids, respectively. BERV ${\beta}3$ showed little amino acid similarity to other betaretroviruses. Phylogenetic analysis showed that it clusters with HERV-K. This is the first report describing the genetic structure and sequence of an entire BERV.

• The Journal of Korean Physical Therapy
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• 제34권5호
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• pp.248-254
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• 2022

Purpose: This study was undertaken to identify the effect of amateur wind musical performance and choir activity on pulmonary function, and to determine the usefulness as a respiration training program by measuring the pulmonary functions of subjects. Methods: A total of 90 subjects (wind instrument players group=30, choir members group=30, control group=30) participated in the experiment. Pulmonary function test (FVC, FEV₁, FEV₁/FVC ratio, MVV, SVC, PEF, FEF 25-75%, IRV, ERV) was conducted using a spirometer (CardioTouch 3000S, Bionet, Seoul, Republic of Korea). Each factor was measured 3 times to meet the American Thoracic Society criteria, and the highest value was used in the analysis. Results: Comparing pulmonary function between the amateur wind instrument players (WP), amateur choir members (CH), and control (CG) groups revealed significant differences in FEV₁, FVC, FEV₁/FVC, and ERV (p<0.05). Highest values were obtained in the WP group. Significant differences were obtained for various factors in the multiple regression analysis of practice year (PY), practice time per week (PTPW), and exercise time per week (ETPW): FEV₁ and FVC in PY, FEV₁/FVC in PTPW, and FEV₁/FVC, MVV, PEF, and FEF (25-75%) in ETPW. Conclusion: Amateur wind instrument performance effectively improves lung function and is useful as a breathing training program for preventing debilitation and improving respiratory function.

• 대한물리치료과학회지
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• 제19권4호
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• pp.47-52
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• 2012

Purpose : The purpose of the study was to examine if a respiratory muscle strengthening training in patients with stroke can improve their pulmonary function. Methods : Volunteers were included for the study if a patient diagnosed stroke more than 6 months and had 24 points or higher in MMSE-K scores. Twenty-eight subjects participated in this study and were randomly divided into two groups; a breathing exercise group(n=14) and a control group(n=14). The intervention for all subjects was conducted for 20minutes, three times a week for 4 weeks. Subjects for the breathing exercise group had the respiratory muscle strengthening training using spiro-tigers, where-as subjects in the control group got their usual treatment ie a postural training. The six-minute walking test(6MWT) and the pulmonary function tests(FVC, $FEV_1$, $FEV_1$/FVC, VC, Vt, IRV and ERV) were employed to assess treatment effects at baseline and after their intervention. Results : Twenty-four subjects finished their 4-week treatment programs. The general characteristics between groups were found to be similar (p>0.05). The pulmonary function between groups were also observed no difference across groups at the baseline measurement (p>0.05). In the post treatment group comparison, subjects in the breathing exercise group showed an increase in lung function with VC ($2.73{\pm}0.80{\ell}$) and Vt ($0.87{\pm}0.38{\ell}$) than those in the control group ($1.91{\pm}0.80{\ell}$ and $0.48{\pm}0.22{\ell}$ respectively) (p<0.05). However, there was no difference found in 6MWT, FVC, $FEV_1$, $FEV_1$/FVC, IRV, and ERV across groups (p>0.05). Conclusion : A significant increase in VC and Vt was found in subjects with stroke, who had four-week training on respiratory muscle strengthening. However, respiratory muscle strengthening showed no effect on walking speed and FVC, $FEV_1$, $FEV_1$/FVC, IRV, and ERV in patients with stroke.

• 한국산학기술학회논문지
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• 제22권5호
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• pp.303-309
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• 2021

본 연구는 보행 훈련시 심박수의 변화에 따라 보행속도를 조절하여 뇌졸중 환자의 심폐기능의 변화를 알아보고자 하였다. 대상자는 만성 뇌졸중 환자 20명을 무작위로 실험군과 대조군으로 분류하여 연구를 진행하였다. 실험군은 심박수 측정기를 착용한 상태로 트레드밀에서 심박수의 변화에 따라 보행속도를 증가 또는 감소시키면서 보행훈련을 실시하였고, 대조군은 대상자의 주관적인 속도에 의해 보행훈련을 실시하였다. 보행훈련 사이에 10분 간격으로 1분씩 휴식시간을 부여했으며 주 3회씩 총 6주간 중재를 실시하였다. 대상자들의 중재이후의 변화를 살펴보기 위하여 폐활량(VC), 호기예비용적(ERV), 흡기예비용적(IRV) 노력성 폐활량(FVC), 1초간 노력성 호기량(FEV1), 최대 호기 속도(PEF)를 측정하여 심폐기능의 변화를 확인하였다. 연구결과 폐활량, 흡기예비용적, 호기예비용적에서 집단과 시기사이에서 상호작용을 나타내었으며 주효과인 집단 및 시기 간 유의한 차이도 나타났다(p<.05), 1초간 노력성 호기량, 노력성 폐활량, 최대 호기속도에서는 그룹과 시기사이에서 상호작용이 나타나지 않았다. 주 효과에서는 집단 간 유의한 차이를 보이지 않았으나(p>.05) 시기 간에는 유의한 차이를 보였다(p<.05). 연구결과 보행과정에서 심박수의 변화에 따라 속도를 변화시켜 훈련을 시행할 경우 심폐기능의 유의한 향상을 보인 것으로 보아 보행 훈련시 속도변화를 통해 훈련을 할 경우 심폐기능의 유의한 변화를 이끌어 낼 수 있을 것으로 판단된다.

• 대한물리치료과학회지
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• 제8권1호
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• pp.885-892
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• 2001

The purpose at this study was comparied at effect the pulmonary function to breathing exercise(BE) in water with on land. The result was as follow: FVC(Forced Vital Capacity) was decreased 1.5% in control group, increased 1.5% in BE on land group and increased 6.5% in water group after BE, but no significant difference in water group. FEV1(forced expiratory volume at one second) was increased 0.2% in the control group, decreased 0.7% in BE on land group and increased 5.7% in BE in water group after BE, but no significant difference in water group. MVV(maximal voluntary ventilation) was significant difference in BE in water group who was increased 12.2% after BE. It was decreased 1.0% in the control group and increased 0.2% in BE on land group. VC(vital capacity) was decreased 1.5% in the control group, increased 6.2% in BE on land group and increased in BE in water group after BE, but no significant difference in water group. IC(Inspiratory Capacity) was decreased 0.5% in the control group, increased 7.5% in BE on land group and decreased 2.0% in BE in water group after BE, but no significant difference on land group. ERV(Expiratory Reserve Volume) was decreased 0.5% in the control group, increased 3.0% in BE on land group and increased 8.5% in BE in water group after BE, but no significant difference in water group.

• The Journal of Korean Physical Therapy
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• 제21권3호
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• pp.25-32
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• 2009

Purpose: This study examined whether breathing exercises might increase the chest expansion and pulmonary function of stroke patients. Methods: Twenty four patients with stroke were assigned randomly into two groups: a combination of diaphragmatic resistive breathing and pursed-lip breathing exercise (CB) group (n=10) and control group (n=14). The CB group completed a 4-week program of diaphragmatic resistive breathing and pursed-lip breathing exercise. The subjects were assessed using the pre-test and post-test measurements of the chest expansion (length for resting, deep inspiration, deep expiration, deep expiration-inspiration) and pulmonary function (forced vital capacity (FVC), forced expiratory volume at one second (FEV1), FEV1/FVC, peak expiratory flow (PEF), vital capacity (VC), tidal volume (TV), expiratory reserve volume (ERV), inspiratory reserve volume (IRV)). Results: A comparison of the chest expansion between the pre and post tests revealed similar rest, deep inspiration, deep expiration, and deep expiration-inspiration lengths in the CB and control groups (p>0.05). A comparison of the pulmonary function between pre and post tests, revealed significant improvements in the FVC, FEV, PEF, VC, IRV, and ERV in the CB group (p<0.05). There was a significant difference in the FVC, FEV1, PEF, VC and IRV between the 2 groups (p<0.05). Conclusion: These findings suggest that breathing exercise should help improve the pulmonary function, such as the volume and capacity. This suggests that the pulmonary functions of stroke patients might be improved further by a continued respiratory exercise program.

• Molecules and Cells
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• 제26권4호
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• pp.404-408
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• 2008

The genome of replication-competent BERV ${\gamma}4$ provirus, which is the most abundant ERV family in the bovine genome, was characterized in detail. The BERV ${\gamma}4$ genome showed that BERV ${\gamma}4$ harbors 8576 nucleotides and has the typical 5'-long terminal repeat (LTR)-gag-pro-pol-env-LTR-3' retroviral organization with a long leader region positioned before the gag open reading frame. Multiple sequences analysis showed that the nucleotide difference between 5' and 3' LTRs was 4.2% (mean value 0.042) in average, suggesting that the provirus formed at most 13.3 million years ago. Gag separated by a stop codon from pro-pol in the same reading frame, while env resides in another reading frame lacking of a functional surface domain. According to the current bovine genome sequence assembly, the full-length BERV ${\gamma}4$ provirus sequences were only found in the chromosomes 1, 2, 6, 10, 15, 23, 26, 28, X, and unassigned, although the partial sequences almost evenly distributed in the entire bovine genome. This is the first detailed study describing the genome structure of BERV ${\gamma}4$, the most abundant ERV family present in bovine genome. Combined with our recent reports on characterization of ERVs in bovine, this study will contribute to illuminate ERVs in the cattle of which no information was previously available.

• 대한통합의학회지
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• 제3권3호
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• pp.89-94
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• 2015

Purpose : This study was analyzed to researched the improvement of the posture and breathing ability on correction method of posture and breathing exercise in Forward Head Posture(FHP) Method : Eighten forward head posture subjects participated in this study. The control group applied to correction method of posture and the experiment group applied to correction method of posture with breathing exercises. Results : The results showed significant improvement in Craniovertebra-Angle on each two group(P<0.05). All the other result showed non-significant in respiratory(Tidal volume, Expiratory residual volume, Inspiratory residual volume) But value of result is slightly improved in after exercise. Conclusion : CVA angle is increased in each group but not increased between experiment group and control group. Total Volume(TV), Inspiratory Reserve Volume(IRV) and Expiratory Reserve Volume(ERV) are a little increased.

• 한국동물학회:학술대회논문집
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• 한국동물학회 2000년도 한국생물과학협회 학술발표대회
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• pp.273.1-273
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• 2000

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