• Asian Pacific Journal of Cancer Prevention
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• v.13 no.5
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• pp.1887-1893
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• 2012

The aim of this study was to detail characteristics of mammary Paget's disease (PD) representing the whole population in China. A total of 4211 female breast cancer inpatients at seven tertiary hospitals from seven representative geographical regions of China were collected randomly during 1999 to 2008. Data for demography, risk factors, diagnostic imaging test, physical examination and pathologic characters were surveyed and biomarker status was tested by immunohistochemistry. The differences of demography and risk factors between PD with breast cancer and other lesions were compared using Chi-square test or t-test, with attention to physical examination and pathological characters. The percentage of PD was 1.6% (68/4211) in all breast cancers. The mean age at diagnosis was 48.1, and 63.2% (43/68) patients were premenopausal. There is no difference in demography and risk factors between PD with breast cancer and other breast cancer (P > 0.05). The main pattern of PD in physical exam and pathologic pattern were patients presenting with a palpable mass in breast (65/68, 95.6%) and PD with underlying invasive cancer (82.4%, 56/68) respectively. The rate of multifocal disease was 7.4% (5/68). PD with invasive breast cancer showed larger tumor size, more multifocal disease, lower ER and PR expression and higher HER2 overexpression than those in other invasive breast cancer (P < 0.05). These results suggested that PD in China is a concomitant disease of breast cancer, and that PD with underlying invasive cancer has more multiple foci and more aggressive behavior compared with other breast invasive cancer. We address the urgent needs for establishing diagnostic and therapeutic guidelines for mammary PD in China.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.28 no.3
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• pp.338-346
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• 1995

Studies on activities of hepatocytes and changes of protein and total RNA contents in liver and muscle tissues associated with the gonadal maturation were performed using the adult rockfish, Sebastes schlegeli collected monthly from the adjacent waters at Poryong, Chungnam, Korea. Hepatosomatic index (HSI) of female increased from September and reached the maximum value (2.58) in February (growing stage of ovary). HSI of male began to increase from October (early maturation stage) and revealed the maximum value (3.20) in April (recovery stage). During the period of yolk formation in oocyte, the amount of glycogen particles and lipids in the hepatocytes of female gradually decreased, but total RNA contents increased. In the hepatocytes of male, a number of lipid droplets remained until the mature stage of testis. With the gonadal development of both sexes, granular endoplasmic reticula (Er) became abundant in the hepatocyte. These Ers might be supposed to have the leading role for the syntheses of protein and vitellogenin in the cytoplasm of the hepatocytes. Protein and total RNA contents in the liver and muscle tissues of female began to increase from January (growing stage) and reached the maximum value in early April (maturation stage), and then decreased in late April (gestation stage). In male, their contents began to increase from October (early maturation stage), thereafter reached the maximum value in December (maturation and copulation stage), and decreased in January (degeneration stage).

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.24
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• pp.10643-10646
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• 2015

Background: To study the relationship between mammographic findings and clinical/pathologic features in women with 1-15mm sized invasive breast cancer. Materials and Methods: We investigated a consecutive series of 134 cases diagnosed in Tianjin Medical University Cancer Institute and Hospital in 2007. Mammographic findings were classified into five groups as follows :1) stellate mass without calcification; 2) non-stellate mass without calcification; 3) intermediate suspicious calcification with or without associated mass; 4) higher probability malignant calcification with or without associated mass; 5) focal asymmetry/distortion without associated calcification. Associations between mammographic and clinical/pathological features (menopause status/family history/histologic grade/lymph node status and ER/PR/HER2 status) was analyzed through logistic regression and chi square tests. Results: Compared to the stellate mass without calcification group, higher probability malignant calcification patients were associated significantly with a positive lymph node status, always presenting in patients who were non-menopausal and with a family history of carcinoma. Conclusions: Higher probability malignant calcifications with or without associated tumor masses are associated with clinical/pathologic features of poor prognosis.

• Fire Science and Engineering
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• v.28 no.1
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• pp.71-78
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• 2014

Complex ethical issues of Emergency Medical Techinician (EMT) out-of hospital emergency medical scene and the ER (Emergency Room) behaviors were studied. The survey was conducted by 500 EMT group members working in the field of ambulance work and general hospital and it was about their work ethics, discussions and solutions about the transferred patients, and ethics regarding Do Not Attempt Resuscitate (DNAR). The survey includes work ethics, awareness about the target job, a discussion on the transfer of patients, measures, and deathbed. Discussions about the patient's condition and diagnosis results were majorly absent during patient transportation at the emergency care scene. More than 90% of emergency care transfer were inappropriate. Sometimes, EMT working in the field facing morally unethical problems beyond their responsibility. When EMT, who can not make death diagnosis, received deathbed related DNAR issues, they gone through severe ethical conflicts. The institutional support and therapy for EMT was weak. In Korea, especially in the accident site, ethical issues education is more needed than DNAR prevalence of education and guidance. If ethics training and guidance are given to EMT, a lot of moral errors in the field can be resolved.

• Korean Journal of Applied Biomechanics
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• v.19 no.4
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• pp.637-645
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• 2009

The purpose of this study was to investigate the biomechanical alterations in the punching motion of 10 elderly women after 12 weeks of taekwonaerobics training. Seven infrared cameras(Qualisys MCU-240) and 2 force platforms(Kistler-9286AA) were used to acquire raw data. The results were as follows. First, the minimum joint angles of the lower limbs had a statistically significant difference between both the dorsiflexion/plantar flexion(1eft, $p=0.001^*$) and the inversion/eversion(both, $p=0.009^*$, $p=0.04^*$) from the ankle angle. There were differences in abduction/adduction(left, $p=0.04^*$) from the knee angle, as well as internal/external rotation(both, $p=0.07^*$, $p=0.02^*$) from the hip angle. Second, the maximum resultant joint moments of the lower limbs had statistically significant differences in the inversion/eversion moment from the ankle joint(both, $p=0.05^*$, $p=0.05^*$), the abduction/adduction moment(left, $p=0.08^*$) from the knee joint, and the internal/external rotation moment(right, $p=0.09^*$) from the hip joint. Third, the maximum resultant joint powers of the lower limbs had a statistically significant difference both in flexion/extension joint powers(both, $p=0.05^*$, $p=0.01^*$) and in abduction/adduction(both, $p=0.02^*$, $p=0.00^*$) from the hip joint, as well as abduction/adduction(left, $p=0.00^*$) from the knee joint, In conclusion, the elderly women were somewhat changed after 12 weeks of taekwonaerobics training.

• Journal of Applied Biological Chemistry
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• v.60 no.4
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• pp.313-319
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• 2017

Strawberries are one of the main commodities in Korea and have been exported over 30 million dollar. And the safety has recently become an important issue in the agro-trade, pesticide residue is most important matter of safe agricultural products. As strawberries can be cultivated using elevated production system, so it is possible to use the drenching. When spraying the pesticides, the use of drenching can be lower amount of residual than using foliar treatment. In this study, time sequential residual amount of pesticides were compared between drenching and foliar application in strawberries. Pesticides were treated with the standard and double dosage and samples were collected at 0, 3, 6, 9, 13, 16 and 21 day and analyzed by LC and LC-MS/MS after liquid-liquid extraction and QuEChERS. Two pesticides were detected less than 1 mg/kg in all samples for drenching treatment. Carbendazim residues in drenching treatment were 5 to 25 times lower than foliar application. And azoxystrobin was not detected in strawberries of drenching treatment.

• The Journal of Korean Academic Society of Nursing Education
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• v.7 no.2
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• pp.264-274
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• 2001

About the patients who visited the emergency department of a hospital, investigative study was performed to assess and to classify them with triage tool, and to estimate the characteristics of them. 210 patients older than 15 years were investigated. Among them 11 patients who had responded inappropriately were excluded and remaining 210 patients were chosen as study subjects. Investigation had been performed for 30 days from Jan. 10, 2001 to Feb. 9, 2001. The triage tool was designed through the modification of triage tools developed by Kim and Choi. The data were analyzed with the SPSS program using mean, standard deviation, frequency, percentage, ANOVA and Scheffe's test. The results were as follows: 1. Of the characteristics of the study subjects, mean age of patients were 55.76 years and 70-79 years group which included 41 patients(20.6%) were most numerous. 101 (51.8%) patients visited emergency room by 119 emergency service and 91(45.7%) patients walked with assistance. 127 patients were cared in internal medicine department. 2. The distribution of triage scores were from minimum 6 points to maximum 18 points with mean $13.76{\pm}2.58$ points. 3. Triage scores had significant relationship with age(F=13.349,P=0.000), visiting method (F=8.832, P=0.000), walking status(F=28.185, p=0.000), care department(F=2.596, P=0.019), and preexisting disease(F=12.012, P=0.000). 4. After trage there were no urgent patient, 35 emergent patients(17.6%),109 subemergent patients(54.8%), and 55 nonemergent patients (27.6%). The result of emergency care were 80 admission(40.2%), 59 discharge (29.6%), 34 ICU admission(17.1%), 14 transfer to other hospital(7%), 10 operation (5%), and 2 death (2%). 5. About the time required for triage, mean duration to triage were $7.54{\pm}2.28$ mins in emergent patients, mean $7.23{\pm}2.50$ mins in subemergent patients and mean $6.49{\pm}2.19$ mins in nonemergent patients. There were no differences in duration to triage according to the severity of triage. 6. Time required in emergency treatment were mean $116.23{\pm}88.10$ in emergent patients mean $101.61{\pm}73.27$ in subemergent patients and mean $81.56{\pm}61.01$ in nonemergent patients. There were no significant difference among groups. This study depicted that triage scores were below the middle level and there were many geriatric patients in this hospital. Among the characteristics of patients, age, visiting method, walking status, care department, and accompanying disease could be data for triage of emergency patients. With triage score of a patient, the outcome of emergency care of a patient could be anticipated and this could be basal data in determining the priority of emergency nursing.

• Koreanishche Zeitschrift fur Deutsche Sprachwissenschaft
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• v.7
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• pp.85-104
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• 2003

In der vorliegenden Arbeit werden die deutschen Satzmodelle $f\"{u}r$ Zwecke des DaF-Unterrichts in Korea untersucht. Dabei gehen wir davon aus, dass man die deutschen Satzmodelle vergleichend mit den koreanischen neu aufbauen sollte, um sie im Deutschunterricht fur Koraner recht benutzen zu konnen. Dafur haben wir hier zunachst untersucht, wie man die koreanischen Satzmodelle im Hinblick auf den didaktischen Zweck modifizieren muss. Unter $Ber\"{u}cksichtigung$ des dabei erzielten Ergebnisses wurden $anschlie{\ss}end$end die deutschen Satzmodelle rekonstruiert. Im Koreanischen wurden die Satzmodelle ab Ende der 1960er Jahre verschiedenartig untersucht. Zwar gibt es bisher noch keine Arbeit, die Ergebnisse dieser Forschungen zusammenfasst, dennoch versuchen wir hier aus einigen bisherigen Untersuchungen einen begrenzten Rahmen von koreanischen Satzmodellen herauszufinden. Als Resultat haben wir funf grundlegende Satzmolle hergestellt: (1) Subjekt + $Pr\"{a}dikat$, (2) Subjekt + $Pr\"{a}dikativ$ + $Pr\"{a}dikat$, (3) Subjekt + Objektiv + $Pr\"{a}dikat$, (4) Subjekt + Adverbiale + $Pr\"{a}dikat$, (5) Subjekt + Obj. + Obj./$Pr\"{a}dikativ$/Advb. + $Pr\"{a}dikat$. Das Modell (1) $umfa{\ss}t$ drei $Pr\"{a}dikate$, die sich nach den Wortarten unterscheiden: (intransitives) Verb, Adjektiv und Substantiv. Auch beim Fall (5) $k\"{o}nnen$ drei verschiedene Untermodelle nach der $Kombinationsm\"{o}glichkeit$ auftreten: Sub + Obj. + $Pr\"{a}d$., Sub. + Obj. + $Pr\"{a}dikativ$ + $Pr\"{a}d$., Sub. + Obj. + Advb. + $Pr\"{a}d$. Auch im Deutschen kann man ahnlich wie im Koreanischen didaktisch geeignete Satzmodelle herausarbeiten. Auch dabei wurden bisherige Untersuchungen zu den deutschen Satzmodellen herangewgen. Zu der $d\"{a}fur$ $ausgew\"{a}hlten$ Terminologie $geh\"{o}ren$ Subjekt(S), $Pr\"{a}dikat(P)$, $Pr\"{a}dkativerganzung(PE)$, $Objekterg\"{a}nzung(OE)$, $Adverbialerg\"{a}nzung(AE)$. In der deutschen Sprache werden nach den $Valenzm\"{o}glich­keiten$ des $Pr\"{a}dikativteils$ folgende Modelle unterschieden: S + P, S + P + PE, S + P + OE, S + P + AE, S + P + OE + OE/PE/AE. Unter die OE werden okk. OE, dat. OE, $pr\"{a}d$. OE, refl. OE usw. subsumiert. Um die Stichhaltigkeit der in dieser Schrift neu festgestellten Satzmodelle zu $\"{u}berpr\"{u}fen$, sollten sie anhand eines Textkorpus heutiger Texte in weiteren Untersuchungen validiert werden. Ferner ist es zu empfehlen, die Anwendbarkeit der hier vorgestellten Satzrnodelle im Deutschunterricht $f\"{u}r$ Koreaner $gr\"{u}ndlich$ zu testen

• Applied Microscopy
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• v.29 no.2
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• pp.149-162
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• 1999

For investigation of the activated carbon on the mouse kidney treated with Pb, the activated carbon (40 mg/kg) and Pb (30 mg/kg) were treated orally for three and six weeks, respectivelly, and observed by the electron microscope. On the glomerulus of the group with only Pb, the basal membrane thicked, projected, and the foot processes fused. On the proximal convoluted tubules, the number of microvilli were decreased and the number of vacuoles and lysosome increased on the cytoplasm. The mitochondria and endoplasmic reticulum were extended and ribosomes dropped from the ER. On the giomerulus of the group with Pb-activated carbon, the basal membrane and the foot processes were merely changed. On the proximal convoluted tubules, the shapes and number of microvilli were not changed and the number of vacuoles, microbodies, and lysosomes decreased. The shapes of mitochondria and endoplasmic reticulum observed almost similar with control group. Th at is, elongated mitochondria and attached ribosomes to endoplasmic reticulum. As result, the activated carbon has positive effect on reducing toxicity of lead in the mouse kidney in the view of electron microscope.

• Korean Journal of Materials Research
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• v.9 no.3
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• pp.234-239
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• 1999

A Abstract Yttria-stabilized zirconia(YSZ) thin films were synthesized by plasma enhanced chemical vapor deposition process. $Zr[TMHD]_4$ $Y[TMHD]_3$ precursors and oxygen were used with the deposition temperature of $425^{\circ}C$ and rf power ranging 0-100 watt. Effects of the deposition parameters were studied by X-ray diffraction and thickness anal­ysis. YSZ thin films have cubic crystal structure with (200) orientation. From the results of EDX analysis, the converte ed content of TEX>$Y_2O_3$ was determined to be 0-36%, and the film thickness was increased with bubbling temperature which is considered to be due to increasing TEX>$Y_2O_3$ flux. The depth profiles of Zr, Y and 0 appeared relatively $\infty$nstant through film thickness. Columnar grains of $1000~2000\AA$ grew vertical to the substrate surface for the case of Ar carri­er gas. In case of He carrier gas, the grain size was observed to be about $1000~2000\AA$. X-ray diffraction data showed the increase of lattice constant with TEX>$Y_2O_3$ content. It was that the presence of the cracks formed during film deposition, partially released the stress generated by the increase of lattice constant.