• 국제학술발표논문집
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• The 1th International Conference on Construction Engineering and Project Management
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• pp.1028-1035
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• 2005

Traditional Industries were planning the major role for Taiwan's economy. However, we need to face the competition from developing countries. Moving manufacturing department to other low salary countries, such as China, can only temporarily release some limited pressure. The final and complete solutions are to equip on R&D, refine techniques, improve management capabilities, upgrade business, and reform physique. Currently there are some ERP systems on the market; however, they are designed for common purpose and difficult to introduce into industry. The expensive price is another factor to make them be popular. In this research we will Object Oriented, Visual Modeling, ER Model and Windows Environment to develop an Integrated Management System for Sports Requisites Industries (IMSSRI). We will integrate all information from all departments such as development, business, material administration, manufacture, shipping, and financial. When development people construct the all modules, components, cutting molds, materials and accessories, IMSSRI will calculate all needed materials and cost for each product. This cost will be used for quotation to report to our customers. When customers confirm the order, system will transfer all necessary materials into Material Administration System. IMSSRI can generate manufacturing forms and material raw lists for manufacture department. All related information such as stocking, returning goods, material requesting, and material returning can be integrated so we can control all details of the whole enterprise. Through the help of this system, we hope we can save man-power, reduce human mistakes, raise management capabilities for tradition manufacturing industries and create another possibility of eternal operating for Taiwan's Industries.

• 한국발생생물학회지:발생과생식
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• 제11권3호
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• pp.187-193
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• 2007

Ethane 1,2-dimethane sulfonate(EDS)는 Leydig 세포의 선별적 사멸을 유도하는 약물로서 가역적인 테스토스테론 결핍 흰쥐를 만드는데 널리 사용된다. 부정소의 구조와 기능 유지는 크게 보아 정소에서 분비되는 테스토스테론에 의존적이지만, 테스토스테론으로부터 유도되는 dihydroxytestosterone(DHT)와 에스트로겐도 중요한 역할을 한다. 본 연구에서는 EDS 주사 후 7주까지 부정소에서의 스테로이드 호르몬 수용체, cyctochrome P450aromatase(P450arom)와 $5{\alpha}$-reductase의 유전자 발현 양상을 조사하였다. 성숙한 수컷 흰쥐($350{\sim}400\;g$)에 EDS를 1회 복강 주사하고(75 mg/kg i.p.) 주사 후 0, 1, 2, 3, 4, 5, 6, 7주가 경과한 날에 희생하였다. 표적 유전자들의 전사 활성은 반 정량적 역전사 중합효소 반응법(semi-quantitative RT-PCRs)으로 측정하였다. Estrogen receptor alpha($ER{\alpha}$) 전사 수준은 EDS 실험군에서 대조군에 비해 주사 1주후에 유의하게 상승했으나(P<0.01) 2주 후부터는 대조군과 유의적인 차이를 보이지 않았다. Estrogen receptor beta($ER{\beta}$)의 전사 수준은 주사 1주후 EDS 실험군에서 대조군에 비해 유의하게 증가했다가(P<0.05), 2주와 3주에는 감소하였고(P<0.05와 P<0.01), 4주와 6주까지는 변동폭을 보이다가 7주 후에는 대조군에 비해 증가하였다(P<0.05). Androgen receptor(AR) 전사 수준은 주사 2주 후에 유의하게 증가하다가(P<0.01) 3주 후부터는 대조군 수준으로 회복하였다. 반면, P450arom는 주사 1주 후부터 3주까지 급격하게 감소했다가(P<0.01 1주와 2주; P<0.05 3주), 4주에 대조군 수준으로 회복하였다. $5{\alpha}$-reductase type 2($5{\alpha}$-RT2)의 mRNA 수준은 4주 후 유의하게 증가했다가(P<0.01), 이후 대조군 수준으로 회복하였다. 본 연구는 EDS 주사가 성 스테로이드 호르몬 수용체들과 안드로겐 전환 효소들의 전사 활성에 가역적인 변화를 유도함을 보여준 것이다. EDS 주사 모델은 부정소의 생리 조절 기작을 이해하는데 유용할 것으로 사료된다.

• International Journal of Control, Automation, and Systems
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• 제1권3호
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• pp.289-300
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• 2003

In this paper, we introduce an identification method in Fuzzy Relation-based Fuzzy Neural Networks (FRFNN) through a hybrid identification algorithm. The proposed FRFNN modeling implement system structure and parameter identification in the efficient form of "If...., then... " statements, and exploit the theory of system optimization and fuzzy rules. The FRFNN modeling and identification environment realizes parameter identification through a synergistic usage of genetic optimization and complex search method. The hybrid identification algorithm is carried out by combining both genetic optimization and the improved complex method in order to guarantee both global optimization and local convergence. An aggregate objective function with a weighting factor is introduced to achieve a sound balance between approximation and generalization of the model. The proposed model is experimented with using two nonlinear data. The obtained experimental results reveal that the proposed networks exhibit high accuracy and generalization capabilities in comparison to other models.er models.

• 정보처리학회논문지A
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• 제11A권7호
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• pp.563-570
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• 2004

유비쿼터스 컴퓨팅 환경은 보안의 강화와 사생활 보호라는 과제를 안고 있다. 접근 제어는 보안 분야의 하나인데, 유비쿼터스 컴퓨팅 환경은 전통적인 정보시스템과는 여러 면에서 특성을 달리하기 때문에 기존의 접근제어 모델을 그대로 적용하기에는 무리가 있다. 본 연구에서는 접근제어 측면에서 유비쿼터스 컴퓨팅 환경을 정의하고 그 환경에서 접근제어의 특성을 분석한 뒤, 그 환경을 위한 접근제어 모델을 개발할 때 필수적으로 고려해야할 요구사항을 제시하였다. 또한 접근제어 모델의 구현시 가능한 세가지 유형에 대해서도 제시하였다.

• 한국전산유체공학회지
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• 제11권2호
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• pp.25-31
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• 2006

A two-dimensional backward facing step flow is simulated by using URANS and Detached Eddy Simulations(DES) approaches. Turbulence models adopted for URANS and DES simulations are Spalart-Allmaras(S-A) model and Shear Stress Transport(SST) model. The target flow with ER=1.125, $Re_H=37,500$ is experimentally studied by Driver & Seegmiller. Various versions of DES have been tested in this paper. Results of the simulations are compared with the experimental data available to evaluate the merits and demerits of URANS and several versions of DES. URANS simulation converges to a steady state and hence unsteady characteristics are not featured. DES simulations in general successfully mimic large scale structures and oscillation characteristics of the flow.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2000년도 하계학술대회 논문집 D
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• pp.2636-2638
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• 2000

In this paper, we show the simple methods of designing the Smith predictor for the long dead time processes. We are using the relay feedback to model the processes in the second-order plus dead time structure. The model is able to represent a various class of processes dynamics including low- or high-order, and monotonic or oscillatory process. A PID type controller is proposed for the main controller in the Smith controller, which insure the stability of overall system. Simulation Examples are also provided to illustrate the effectiveness and applicability of the proposed controller.

• Smart Structures and Systems
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• 제2권1호
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• pp.61-80
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• 2006

The concept of structural vibration control is to absorb vibration energy of the structure by introducing auxiliary devices. Various types of structural vibration control theories and devices have been recently developed and introduced into mechanical systems. One of such devices is damper employing controllable fluids such as ElectroRheological (ER) or MagnetoRheological (MR) fluids. MagnetoRheological (MR) materials are suspensions of fine magnetizable ferromagnetic particles in a non-magnetic medium exhibiting controllable rheological behaviour in the presence of an applied magnetic field. This paper presents the modelling of an MRfluid damper. The damper model is developed based on Newtonian shear flow and Bingham plastic shear flow models. The geometric parameters are varied to get the optimised damper characteristics. The numerical analysis is carried out to estimate the damping coefficient and damping force. The analytical results are compared with the experimental results. The results confirm that MR damper is one of the most promising new semi-active devices for structural vibration control.

• 한국정보기술응용학회:학술대회논문집
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• 한국정보기술응용학회 2001년도 추계공동학술대회 논문자료집 정보화 젼략 패러다임의 변화에 대한 보기술의 대응
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• pp.169-171
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• 2001

본 논문에서는 XML(eXtensible Markup Language)을 위한 데이터 모델을 제시하기 위해 현재 광범위하게 사용되고 있는 관계형 데이터베이스(relational database) 개념을 적용한다. 관계형 데이터베이스는 업무 요구사항의 분석으로부터 고수준의 개념적 데이터 모델을 사용해서 데이터베이스에 대한 개념적 스키마(conceptual schema)를 생성한 다음, 고수준 개념적 데이터 모델을 구현 데이터 모델로 변환하여 논리적 데이터베이스 스키마를 생성한다. 이때, 고수준 개념적 데이터 모델링의 대표적인 방법으로 ER모델을 사용하고, 구현 데이터 모델로 관계 모델(relation model)을 사용한다. XML은 문서의 논리적 구조를 정의하는 DTD와 XML Schema 등을 갖는다. XML의 DTD와 정보 모델링 기법인 E/R 모델은 모두 작은 세계(real world)를 모델링하는 도구들이라고 할 수 있다. 본 논문에서는 XML의 DTD와 E/R 모델의 구성요소들을 분석하여 서로 사상(mapping)시키는 'XML을 위한 데이터 모델(A Data Model for XML)'을 제시한다. 최종적으로 제시된 XML을 위한 데이터 모델에 의해 작은 세계(real world)을 모델링하는 XML DTD에서 정의한 구조(XML Structure)을 따르는 유효한 XML문서(validate XML document)들은 관계형 데이터베이스에 저장할 수 있게 된다.

• Bulletin of the Korean Chemical Society
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• 제21권9호
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• pp.923-928
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• 2000

[FeIII(BBA)DBC]ClO4 as a new functional model for catechol dioxygenases has been synthesized, where BBA is a bis(benzimidazolyl-2-methyl)amine and DBC is a 3,5-di-tert-butylcatecholate dianion.The BBA complex has a structuralfeature that iron cent er has a five-coordinate geometry similar to that of catechol dioxygenase-substrate complex.The BBA complex exhibits strong absorptionbands at 560 and 820 nm in CH3CN which are assigned to catecholate to Fe(III) charge transfer transitions. It also exhibits EPR signals at g = 9.3 and 4.3 which are typical values for the high-spin FeIII (S = 5/2) complex with rhombicsymmetry. Interestingly, the BBA complex reacts with O2 within an hour to afford intradiol cleavage (35%) and extradiol cleavage (60%) products. Surprisingly, a green color intermediate is observed during the oxygenation process of the BBA com-plex in CH3CN. This green intermediate shows a broad isotropic EPR signal at g = 2.0. Based on the variable temperature EPR study, this isotropic signalmight be originated from the [Fe(III)-peroxo-catecholate] species havinglow-spin FeIII center, not from the simple organic radical. Consequently,it allows O2 to bind to iron cen-ter forming the Fe(III)-superoxide species that converts to the Fe(III)-peroxide intermediate. These present data can lead us tosuggest that the oxygen activation mechanism take place for the oxidative cleavingcatechols of the five-coordinate model systems for catechol dioxygenases.

• Asian Pacific Journal of Cancer Prevention
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• 제13권2호
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• pp.479-482
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• 2012

Aim: Soy foods are the major source of isoflavones, which are believed to play important roles in genesis of breast cancer and its progression. We here conducted a prospective study to evaluate the association of soy isoflavone food consumption with breast cancer prognosis. Methods: A prospective study was performed from January 2004 and January 2006 in China. Trained interviewers conducted face-to-face interviews using a structured questionnaire to collect information on dietary habits and potential confounding factors. The relative risk [hazard ratio (HR)] and 95% CI were calculated from the Cox regression model for all significant predictors from cancer diagnosis to the endpoint of the study (event). Results: After a median follow up of 52.1 months (range, 9-60 months), a total of 79 breast cancer related deaths were recorded in our study, risk being inversely associated with a high intake of soy isoflavone. With an average intake of soy isoflavone above 17.3 mg/day, the mortality of breast cancer can be reduced by about 38-36%. We also found the decreased breast cancer death with high soy protein intake, with a HR (95% CI) of 0.71 (0.52-0.98). Stratified analysis with reference to the ER status, further demonstrated a better prognosis of ER positive breast cancer with a high intake of soy isoflavone (HR 0.59, 0.40-0.93). Conclusion: Our study shows the soy food intake is associated with longer survival and low recurrence among breast cancer patients. A cohort study with a larger sample size and long term follow-up is now needed.