• Venture DIGEST
• /
• no.1 s.126
• /
• pp.28-29
• /
• 2009

팍팍하게 돌아가는 일상 속에서 나만의 눈부신 무언가 하나를 찾았다면 그 만큼 보람되고 소중한 것이 뭐가 있을까. 대한민국 게임 산업의 메카이자, 전 세계 게이머들의 이목을 받고 있는 글러벌 벤처기업, 위메이드 엔터테인먼트(Wemade Entertainment / 이하 위메이드). 위메이드는 'Fun 경영'을 실천하며 사내동호회 활동을 적극 지원한다. 그 중 꽃꽂이 동호회인 '위메이드 플라워 가든(Wemade Flower Garden)'이 모인 현장을 찾아갔다.

• Journal of the Korean Society of Food Science and Nutrition
• /
• v.31 no.4
• /
• pp.583-588
• /
• 2002

Two microorganisms isolated from soybean curd residue (biji) were identified as Enterococcus faecium (51% homology) and Lactobacillus rhamnosus (99.5% homology) by using gram positive identification (GPI) card and API 50 CHL kit, respectively. Ent. faecium grew well in micronized full-fat soyflour (MFS) milk, indicating pH 4.9, 0.38% acidity and 1.8$\times$10$^{9}$ CFU/$m\ell$ of viable cell counts after fermentation for 20 hr. L. rhamnosus LL showed pH 6.5 and 4.6$\times$10$^{8}$ CFU/$m\ell$ viable cell counts, but enhanced acid production in MFS milk mixture fortified with skim milk or by the addition of 1% of glucose and lactose. On the other hand, Ent. faecium LL did not show increased acid production in MFS/skim milk and MFS milk fortified with sugar. The MFS/skim milk fermented by L. rhmnosus LS and Ent. faecium LL showed 600 mg% and 350 mg% lactic acid, respectively.

• Asian Pacific Journal of Cancer Prevention
• /
• v.15 no.24
• /
• pp.10949-10955
• /
• 2015

Liver cancer is one of leading digestive malignancies with high morbidity and mortality. There is an urgent need for the development of novel therapies for this deadly disease. It has been proven that asparagus polysaccharide, one of the most active derivates from the traditional medicine asparagus, possesses notable antitumor properties. However, little is known about the efficacy of asparagus polysaccharide as an adjuvant for liver cancer chemotherapy. Herein, we reported that asparagus polysaccharide and its embolic agent form, asparagus gum, significantly inhibited liver tumor growth with transcatheter arterial chemoembolization (TACE) therapy in an orthotopic hepatocellular carcinoma (HCC) tumor model, while significantly inhibiting angiogenesis and promoting tumor cell apoptosis. Moreover, asparagine gelatinous possessed immunomodulatory functions and showed little toxicity to the host. These results highlight the chemotherapeutic potential of asparagus polysaccharide and warrant a future focus on development as novel chemotherapeutic agent for liver cancer TACE therapy.

• Korean Journal of Plant Resources
• /
• v.35 no.2
• /
• pp.169-182
• /
• 2022

This study was conducted to predict the distribution of rare·endemic plants (Sophora koreensis Nakai) in the border forests where wildfire damage occurred and to quantify the damage. For this purpose, we tried to derive more accurate results through forest area damage (NBR) according to the Burn severity of wildfires, damage by tree species type (Vegetation map), and MaxEnt model. For Burn severity analysis, satellite imagery (Landsat-8) was used to analyze Burn severity (ΔNBR2016-2015) and to derive the extent of damage. To prepare the Vegetation map, the land cover map prepared by the Ministry of Environment, the Vegetation map prepared by the Korea Forest Service, and the vegetation survey conducted by itself were conducted to prepare the clinical map before and after the forest fire. Lastly, for MaxEnt model analysis, the AUC value was derived by using the habitat coordinates of Sophora koreensis Nakai based on the related literature and self-report data. As a result of combining the Maxent model analysis data with the Burn severity data, it was confirmed that 45.9% of the 44,760 m² of habitat (predicted) area of Sophora koreensis Nakai in the wildfire damaged area or 20,552 m², was damaged.

• Journal of Dental Anesthesia and Pain Medicine
• /
• v.20 no.2
• /
• pp.83-87
• /
• 2020

Foreign body (FB) ingestion is commonly seen in the ear nose and throat (ENT) field, with different presentations and sequelae. FBs can arrest in the upper aerodigestive tract or continue further down into either the airway tract to the bronchus or the digestive tract to the intestines. The pathway of an FB depends on the size and shape of the FB and how sharp its edges are. Since the 20th century, the use of disposable stainless-steel needles in the oral cavity has proven to be an effective and safe method for performing various intraoral procedures like dental infiltration or a root canal wash. Complications from their use are rare. Generally, dental needle breakages are caused by patients biting the needle, incorrect injection techniques, or inadequate preventative measures. The sudden movement of a patient during a procedure is one of the most common causes of breakage. Occasionally, needles are swallowed during dental procedures such as a root canal. Here, we report a case of a patient that swallowed a broken needle during a dental procedure. A few days later, the patient presented with neck pain, swelling, and a FB sensation. When the patient presented, she claimed that her symptoms had onset after consuming a meal containing duck meat. Initially, the patient was diagnosed as having ingested a duck bone. However, intraoperatively, the FB was discovered to be an injection needle that had migrated from the throat to the neck.

• Korean Journal of Head & Neck Oncology
• /
• v.11 no.1
• /
• pp.24-29
• /
• 1995

Melanoma of the mucous membrane is a rare condition and has the worse prognosis than that of any other sites. It is usually asymptomatic in early stage and difficult to find out the primary lesion by visual examination, and these facts lead to delay in diagnosis and reduce the curability. The major factor of failure in treatment of melanoma is local recurrence rather than regional spread. Because the radical procedure is difficult in head and neck lesion due to anatomical limitation, radiation therapy and chemotherapy can be used in the treatment of local recurrence. We experienced two cases of nasopharyngeal melanoma in advanced stage and treated them with radiation therapy and/or chemotherapy. And both patients showed relatively favorable response to these palliative treatments.

• Journal of Microbiology and Biotechnology
• /
• v.18 no.8
• /
• pp.1357-1363
• /
• 2008

The $P_{entC}$ promoter of the entCERA operon encoding enzymes for enterobactin biosynthesis in Escherichia coli is tightly regulated by the availability of iron in the culture medium. In iron-rich conditions, the $P_{entC}$ promoter activity is strongly repressed by the global transcription regulator Fur (ferric uptake regulator), which complexes with ferrous ions and binds to the Fur box 19-bp inverted repeat. In this study, we have constructed the expression vector pOS2 containing the $P_{entC}$ promoter and characterized its repression, induction, and modulation by quantifying the expression of the lacZ reporter gene encoding $\beta$-galactosidase. $\beta$-Galactosidase activities of E. coli transformants harboring pOS2-lacZ were highly induced in the presence of divalent metal ion chelators such as 2,2'-dipyridyl and EDTA, and were strongly repressed in the presence of excess iron. It was also shown that the basal level $\beta$-galactosidase expression by the $P_{entC}$ promoter was drastically decreased by incorporating the fur gene into the expression vector. Since the newly developed iron chelator-inducible expression system is efficient and cost-effective, it has wide applications in recombinant protein production.

• Asia-Pacific Journal of Business Venturing and Entrepreneurship
• /
• v.10 no.5
• /
• pp.219-231
• /
• 2015

Open innovation is known to have a significant impact on the performance of enterprise innovation. The role of open innovation is more critical due to small scale and limitation on the available resources for the venture company. This study focused on the relationship among Entrepreneurship(ENT), Innovation Capability(IC), and External Cooperation(EC), which affect Technological Innovation Performance(TIP) to maximize TIP. Empirical study was proceeded to analyze the relationships among ENT, IC, EC, and TIP for venture companies in Busan. ENT was verified to have a positive impact on IC, EC, and TIP. IC was done on EC and TIP. EC was done on TIP. Each of IC and EC showed positive mediating role in the relationship between ENT and TIP. Finally, IC and EC together performed positive mediating role in the relationship between ENT and TIC.

• Natural Product Sciences
• /
• v.15 no.1
• /
• pp.50-54
• /
• 2009

A simple and reliable reversed phase HPLC method was developed to determine pharmacologically active compounds ent-continentalic acid, kaurenoic acid, and continentalic acid from the roots of Aralia cordata. Quantitative analysis of diterpenoids of A. cordata were performed by reverse phase C-18 column using a isocratic of acetonitrile : 0.1% trifluoroacetic acid(70:30) with UV detection at 205 nm. The correlation coefficients of each calibration curve of ent-continentalic acid, kaurenoic acid, and continentalic acid were 0.9987, 0.9983, and 0.9986, respectively. The detection limit of ent-continentalic acid, kaurenoic acid, and continentalic acid were $0.5{\sim}1.0\;{\mu}g/mL$, respectively. The contents of ent-continentalic acid (1), kaurenoic acid (2), and continentalic acid (3) of the roots of A. cordata collected from seventeen district markets in Korea were $0.09{\sim}0.75\;mg/g$, $1.09{\sim}5.43\;mg/g$, and $2.69{\sim}9.08\;mg/g$, respectively.

• Journal of Digital Convergence
• /
• v.16 no.1
• /
• pp.125-134
• /
• 2018

This study focused on the study of the moderating effects of absorptive capacity(AC) of venture firms on the technological innovation performance(TIP). For this purpose, this study analyzed the relationship between entrepreneurship(ENT), innovation competence(INC), external cooperation(EXO) and AC affecting the performance of technological innovation activities in venture companies in the area of Busan. As a result of analysis, the AC showed a role of moderating processes, in which ENT have affected the INC, and ENT, INC, and EXO have affected the TIP. Secondly, several relationships which have positively influenced or mediated, have been presented. ENT has positively influenced INC, EXO, & TIC. INC have done so EXC & TIP. EXC have done so TIP. Each of INC and EXC has been positively mediating the relationship between ENT & TIP.