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Studies on Bioactive Polysaccharide Isolated from Agaricus bisporus (양송이 버섯의 생물활성 다당류에 관한 연구)

  • Lim, En-Jung;Sung, Ha-Chin;Kweon, Mee-Hyang
    • Applied Biological Chemistry
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    • v.41 no.1
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    • pp.60-66
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    • 1998
  • During the screening for anti-complementary activity from 10 kinds of edible mushrooms, an alkali extract of Agaricus bisporus showed the highest activity through the complement fixation test. The crude anti-complementary material(AB-0) from Agaricus bisporus was obtained by the alkali extraction using 1 N NaOH containing 5% urea$(65^{\circ}C)$, followed by methanol reflux, dialysis and lyophilization. The fraction AB-O showed potent anit-complementary and anti-tumor activity against sarcoma-180 injected mice. The fraction AB-0 was divided into 5 fractions(AB-20, AB-40, AB-60, AB-80, AB-A) by gradual acetone precipitation. Among them fraction AB-20 having the highest activity and yield was found to contain 39% carbohydrate and 46% protein. The anti-complementary protein-bound polysaccharide AB-20 consisted of glucose, arabinose, xylose, galactose and mannose in a molar ratio of 6.49 : 1.98 : 1.24 : 1.00 : 0.71, respectively and its main component amino acids were alanine(20.59%), isoleucine(16.85%), glutamine+glutamic acid(14.12%) and leucine (13.83%). The anti-complementary activity of AB-20 was decreased greatly by periodate oxidation, but decreased slightly by pronase digestion. This indicates that polysaccharide moiety is corelated with the anti-complementary activity and that protein is also involved in the activity.

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Design and Implementation of Multiple Filter Distributed Deduplication System Applying Cuckoo Filter Similarity (쿠쿠 필터 유사도를 적용한 다중 필터 분산 중복 제거 시스템 설계 및 구현)

  • Kim, Yeong-A;Kim, Gea-Hee;Kim, Hyun-Ju;Kim, Chang-Geun
    • Journal of Convergence for Information Technology
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    • v.10 no.10
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    • pp.1-8
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    • 2020
  • The need for storage, management, and retrieval techniques for alternative data has emerged as technologies based on data generated from business activities conducted by enterprises have emerged as the key to business success in recent years. Existing big data platform systems must load a large amount of data generated in real time without delay to process unstructured data, which is an alternative data, and efficiently manage storage space by utilizing a deduplication system of different storages when redundant data occurs. In this paper, we propose a multi-layer distributed data deduplication process system using the similarity of the Cuckoo hashing filter technique considering the characteristics of big data. Similarity between virtual machines is applied as Cuckoo hash, individual storage nodes can improve performance with deduplication efficiency, and multi-layer Cuckoo filter is applied to reduce processing time. Experimental results show that the proposed method shortens the processing time by 8.9% and increases the deduplication rate by 10.3%.

Mitral Valve Replacement in Children Less Than 16 years of Age (소아에서의 승모판치환술)

  • 이흥렬;홍유선
    • Journal of Chest Surgery
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    • v.29 no.10
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    • pp.1090-1094
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    • 1996
  • From February 1980 to September 1995, 31 children between 2 months and 15 years of age with mitral valve disease have undergone mitral valve replacement(MVR) at Yonsei Cardiovascular Center and com- plete follow-up has been obtained on 28 patients. There were 10 males and 18 females whose weight ranged from 4.9kg to 56kg. Two patients died early postopeiatively and the overall hospital mortality rate was 7.1%. These two were infants but there were no statistically significant difference in overall mortality among the age groups(p=0.13). The valve related complication rate was 57.1% in children younger than 5 years of age, which showed higher complication rate compared to older patients(p< 0.05). The bioprosthetic valve have been applied in 7 patients, and its 5-year valve failure-free survival rate was 50% . No mechanical valve failu e had occurred in 21 patients. In considering high re-replacement rate of bioprosthetic valve, mechanical valve is recommended despite its possibility of bleeding and thromboembolic complications. However, the consequences of increasing body size and long-term interposition of a rigid prosthesis in a growing heart will require second valve replacement. En conclusion, mitral valve replacement can be performed tilth satisfactory long-term survival in children, although younger mean age of the children has an important influence on early mortality and com- plication rate. And therefore mitral valve replacement in children younger than 5 years of age needs special consideration.

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A Phenomenological Approach toward The Problems of Squash Referee's Decision Making Experience (스쿼시 심판들이 경험하는 판정어려움에 대한 현상학적 접근)

  • Lee, Byung-Hyuk;Lee, So-Mi
    • Journal of Digital Convergence
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    • v.16 no.2
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    • pp.471-477
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    • 2018
  • The Journal of Digital Policy & Management. This space is for the abstract of your study in EnThis research aims to analyze the difficulties associated with the squash referee's decision by using the phenomenological analysis of Giorgi. With such approach, this paper investigated the fundamental causes of the difficulties of the decision making process of the referee, and then argues the needs for eliminating such causes. Five referees were recruited as the study participants, among the experienced referees with more than 10-year experience and 2nd grade certification, issued by the Korea Squash Federation. The research was conducted between June 2015 and July 2016. Participatory observation, semi-structured in-depth interview. Following Giorgian four-step phenomenological analysis, all transcribed interview data were categorized into three components-'problems from the individual situation', 'problems from the social situation', and 'problems from the circumstantial situation'. Although the referees are one of major factors that determine the success and failure of the game, their working condition is far from the ideal, as observed in the problems above. Therefore, to improve the quality of the judgement, it is most important to reward the referees, who are the subject of the decision, with better economic treatment. Such improvement of the working condition of the referees is also highly related with the reproduction and professionalization of the referees.

Blood Protein Adsorption and Platelet Activation on an Ultra-hydrophilic Substrate (초친수성 표면에서 혈장 단백의 흡착 및 혈소판의 변화에 관한 연구)

  • Park, Nam-Hee;Chun, Bae-Hyeock;Je, Hyung-Gon;Lee, Jun-Wan;Lee, Jae-Won
    • Journal of Chest Surgery
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    • v.40 no.4 s.273
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    • pp.273-279
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    • 2007
  • Background: We evaluate the efficacy of ultra-hydrophilic coated bypass circuits in comparison with uncoated bypass circuits in a porcine cardiopulmonary bypass model. Material and Method: Normothermic cardiopulmonary bypass was peformed in 10 anesthetized pigs via the left atrium and ascending aorta with a centrifugal biopump. Ultra-hydrophilic coated bypass circuits wore used in 5 pigs (the study group) and uncoated bypass circuits were used for the control group. Platelet counts and platelet aggregation tests were peformed. The thrombin-antithrombin(TAT) complex level and total protein level were evaluated. Result: There were no significant changes En the platelet counts and aggregation ability of both groups. The TAT complex levels were not different between the two groups. The total protein level was significantly lower in the control group after cessation of cardiopulmonary bypass. Conclusion: The clinical effects of ultra-hydrophilic coating circuits were not remarkable, in terms of reducing inflammatory reaction and protection of platelet function. However, the effect of protection for blood protein adsorption might be acceptable.

Production Techniques for Mobile Motion Pictures base on Smart Phone (스마트폰 시장 확대에 따른 모바일 동영상 편집 기법 연구)

  • Choi, Eun-Young;Choi, Hun
    • The Journal of the Korea Contents Association
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    • v.10 no.5
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    • pp.115-123
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    • 2010
  • Because of development of information technology, moving picture can run various platforms. We should consider and apply users' attitude as well as production technique because convergence between mobile and media technology may be increased full-browsing service using mobile device. Previous research related to production technique in various platforms only focus on video quality and adjustment of screen size. However, besides of technical side, production techniques should be changed such as image production as well as image editing by point of view aesthetic. Mise-en-scene such as camera angle, composition, and lighting is changed due to HD image. Also image production should be changed to a suitable full-browsing service using mobile device. Therefore, we would explore a new suitable production techniques and image editing for smart phone. To propose production techniques for smart phone, we used E-learning production system, which are transition, editing technique for suitable converting system. Such as new attempts are leading to new paradigm and establishing their position by applying characteries such as openness, timeliness to mobile. Also it can be extended individual area and established as expression and play tool.

Evaluation of Testosterone Metabolites/Dehydroepiandrosterone As the Indicators of Testosterone Administration in Horse Doping (경주마 약물검사에서 testosterone 투여 여부표지자로서의 testosterone 대사체들에 대한 dehydroepiandrosterone의 비율 평가)

  • Kim, Jin Young;Choi, Man Ho;Kim, Sung Jean;Kyong, Jin Burm;Chung, Bong Chul
    • Analytical Science and Technology
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    • v.12 no.3
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    • pp.190-195
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    • 1999
  • The metabolism of testosterone ($17{\beta}$-hydroxy-androst-4-en-3-one) was confirmed in horse after a single intramuscular administration of testosterone cypionate (750 mg). Solvent extracts of urine obtained with enzymatic hydrolysis and methanolysis were analyzed by GC/MS after oxime t-butyldimethylsilyl (oxime-TBDMS) derivatization. The structures of four urinary metabolite after testosterone administration in horse were determined based on EI mass spectra and $5{\alpha}$-androstane-$3{\beta}$, $17{\alpha}$-diol and $5{\alpha}$-androstane-$3{\beta}$-ol-17-one as major was confirmed with authentic standard. Also the concentrations of $5{\alpha}$-androstane-$3{\beta}$, $17{\alpha}$-diol, $5{\alpha}$-androstane-$3{\beta}$, $17{\beta}$-diol, dehydroepiandrosterone (DHEA), $5{\alpha}$-androstane-$3{\beta}$-ol-17-one and testosterone were determined in the urine of normal subjects and the urine after administration. The recovery and detection limit in the most drugs were 86.3~94.7% and 1~3 ppb, respectively. Correlation coefficients for calibration were in the range of 0.984~0.999. Excretion profile of testosterone presents the rapid and large increasement up to maximum values at days 5 after administration and the slow regression. The relative ratios of testosterone, its metabolites over DHEA were determined for indication of testosterone administration in horse doping.

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Monitoring of Ochratoxin in Alcoholic Beverages (주류의 오크라톡신 모니터링)

  • Lee, Joon-Goo;Kang, Young-Woon;Jeong, Ji-Hye;Noh, Mi-Jung;Ahn, En-Sook;Lee, Kwang-Ho;Kim, Mee-Hye
    • Korean Journal of Food Science and Technology
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    • v.44 no.2
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    • pp.235-239
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    • 2012
  • This research was conducted to monitor ochratoxin A in wine, beer, $makgeolli$ and fermented alcoholic beverages to estimate the exposure to ochratoxin A in the assorted alcoholic beverages. The analytical method for ochratoxin A was based on immuno-affinity column clean up followed by HPLC-FLD. Ochratoxin A was detected in 30 samples of 177 wine (17%), 25 samples of 106 beer (23.6%), 11 samples of 74 $makgeolli$ (14.9%), and 7 samples of 74 fermented alcoholic beverages (9.5%). The average levels of ochratoxin A were 0.039 ng/mL in wine, 0.010 ng/mL in beer, 0.023 ng/mL in $makgeolli$, and 0.014 ng/mL in fermented alcoholic beverages. The daily dietary exposure level of ochratoxin A estimated by using the report on national health and nutrition survey were 0.039 ng/b.w.day from wine, 0.010 ng/b.w.day from beer, 0.023 ng/b.w.day from $makgeolli$, and 0.014 ng/b.w.day from fermented alcoholic beverage.

Performance Evaluation of the Iterative Demapping and Decoding based DVB-T2 BICM module (Iterative Demapping and Decoding 기반 차세대 유럽형 디지털 지상파 방송 시스템(DVB-T2)의 BICM 성능 평가)

  • Jeon, Eun-Sung;Seo, Jeong-Wook;Yang, Jang-Hoon;Kim, Dong-Ku
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.36 no.2A
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    • pp.172-178
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    • 2011
  • In this paper, the performance of bit interleaved of coded and modulation(BICM) module of the second generation of digital terrestrial television broadcasting system(DVB-T2) is evaluated with the help of computer simulation. The frame error rate performance is studied in AWGN, Rayleigh fading and 15% erasure channels. In addition, iterative receiver is considered that exchanges extrinsic information between the rotated demapper and the LDPC decoder. Through the simulation it is observed that under the flat fading Rayleigh channel, about 1.2dB gain at FER of $10^{-4}$ is introduced when rotated constellation and iterative demapping and decoding are employed. Under the 15% earasure channel, rotated constellation gives performance gain of about 5dB at BER of $10^{-4}$ and when IDD is applied, additional performance gain of about 3dB can be achieved.

The Effect of Additives on the Preparation of Nanosized TiO2 Particles (나노크기 TiO2의 제조에 미치는 첨가제 영향)

  • Kim, Seok-Hyeon;Na, Seok-En;Kim, Si-Young;Kim, Seong-Soo;Ju, Chang-Sik
    • Korean Chemical Engineering Research
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    • v.51 no.4
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    • pp.426-431
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    • 2013
  • Nanosized $TiO_2$ particles were prepared from titanium (IV) sulfate solution using base solutions at low reaction temperature ($95^{\circ}C$) and atmospheric pressure by hydrothermal precipitation method without calcination. The effects of preparation conditions, such as kind of base solutions (NaOH, $NH_4OH$, Monoethanolamine, Diethanolamine, Triethanolamine) and surfactants (CTAB, Span 20, SDBS), concentration of surfactants, temperature and pH, on the physical properties of $TiO_2$ particles have been investigated by XRD, SEM and Zeta-potential meter. Absorption area was also investigated by DRS in order to confirm the photocatalytic activity of the nanosized $TiO_2$ particles. It was turned out that, among base solutions, NaOH provides the smallest $TiO_2$ particles with excellent crystallinity. And cationic surfactant (CTAB) prepared smaller $TiO_2$ particles than any other surfactants. When CTAB is added in the concentration ratio of $Ti(SO_4)_2$:CTAB=10:1, $TiO_2$ particles with particle diameter of 5.8 nm were prepared. This is approximately 1/10 of that prepared without CTAB.