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Associations Between Heart Rate Variability and Symptom Severity in Patients With Somatic Symptom Disorder (신체 증상 장애 환자의 심박변이도와 증상 심각도의 연관성)

  • Eunhwan Kim;Hesun Kim;Jinsil Ham;Joonbeom Kim;Jooyoung Oh
    • Korean Journal of Psychosomatic Medicine
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    • v.31 no.2
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    • pp.108-117
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    • 2023
  • Objectives : Somatic symptom disorder (SSD) is characterized by the manifestation of a variety of physical symptoms, but little is known about differences in autonomic nervous system activity according to symptom severity, especially within patient groups. In this study, we examined differences in heart rate variability (HRV) across symptom severity in a group of SSD patients to analyze a representative marker of autonomic nervous system changes by symptoms severity. Methods : Medical records were retrospectively reviewed for patients who were diagnosed with SSD based on DSM-5 from September 18, 2020 to October 29, 2021. We applied inverse probability of treatment weighting (IPTW) methods to generate more homogeneous comparisons in HRV parameters by correcting for selection biases due to sociodemographic and clinical characteristic differences between groups. Results : There were statistically significant correlations between the somatic symptom severity and LF (nu), HF (nu), LF/HF, as well as SD1/SD2 and Alpha1/Alpha2. After IPTW estimation, the mild to moderate group was corrected to 27 (53.0%) and the severe group to 24 (47.0%), and homogeneity was achieved as the differences in demographic and clinical characteristics were not significant. The analysis of inverse probability weighted regression adjustment model showed that the severe group was associated with significantly lower RMSSD (β=-0.70, p=0.003) and pNN20 (β=-1.04, p=0.019) in the time domain and higher LF (nu) (β=0.29, p<0.001), lower HF (nu) (β=-0.29, p<0.001), higher LF/HF (β=1.41, p=0.001), and in the nonlinear domain, significant differences were tested for SampEn15 (β=-0.35, p=0.014), SD1/SD2 (β=-0.68, p<0.001), and Alpha1/Alpha2 (ß=0.43, p=0.001). Conclusions : These results suggest that differences in HRV parameters by SSD severity were showed in the time, frequency and nonlinear domains, specific parameters demonstrating significantly higher sympathetic nerve activity and reduced ability of the parasympathetic nervous system in SSD patients with severe symptoms.

Nutritional Status of Intensive Care Unit Patients According to the Referral to the Nutrition Support Team and Compliance with the Recommendations (영양집중지원팀 자문 의뢰 및 순응 여부에 따른 중환자실 환자의 영양상태 비교)

  • Sohn, Yunjin;Hyun, Taisun
    • Korean Journal of Community Nutrition
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    • v.27 no.2
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    • pp.121-131
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    • 2022
  • Objectives: This study aimed to examine the effectiveness of the intervention of the nutrition support team (NST) on the nutritional status of critically ill patients. Methods: The medical records of 176 adult patients who were admitted to the intensive care unit and received enteral or parenteral nutrition for more than 7 days were retrospectively analyzed. The patients were classified into the NST and non-NST groups according to whether they were referred to the NST or not. The NST group was further classified into the compliance and non-compliance groups depending on their compliance with the NST recommendations. Results: The NST referral rate was 56.8%, and the rate of compliance with the NST recommendations was 47.0%. Significantly higher energy and protein were provided to the NST and the compliance groups than to the non-NST and the non-compliance groups. The proportion of patients who reached the target calories after the initiation of enteral nutrition was significantly higher in the NST and the compliance groups than in the non-NST and the non-compliance groups. The serum albumin and hemoglobin levels significantly decreased in every group, but the changes were significantly lower in the compliance group. The nutritional status at discharge from the intensive care unit compared to the status at admission was significantly worse in the NST, non-NST, and non-compliance groups. However, the status was maintained in the compliance group. The length of stay in the intensive care unit was significantly shorter in the compliance group. Conclusions: Compliance with the NST recommendations was found to provide more calories and protein and prevent the deterioration of the nutritional status of critically ill patients. Therefore, effective communication between medical staff and the NST from the early stages of admission to the intensive care unit is needed to improve referrals to the NST and compliance with the recommendations.

A Study on the Ametropia of High School Students in Jeonbuk Province (전북 지역 고등학생 비정시에 관한 연구)

  • Doo, Ha-Young;Sim, Sang-Hyun;Choe, Oh-Mok;Gang, Myoung-Jin
    • Journal of Korean Ophthalmic Optics Society
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    • v.7 no.2
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    • pp.67-71
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    • 2002
  • To investigate the ametropia and refractive error of 364 ametropic eyes en the 182 high school students in Jeonbuk provicne, the visual acuity test was performed by the object and subject method. The results were as follows. 1. The eye types were 85.7% positive for myopia, 6.6% for emmetropia and 7.6% hyperopia, respectively. 2. The abnormal refraction eyes were 30.8% positive for simple myopia, 58.5% for myopia compound astigmatism, 7.5% for myopia simple astigmatism, and 1.8% for simple hyperopia, 1.3% for hyperopia compound astigmatism, 1.9% for hyperopia simple astigmatism, respectively. 3. The axes of astigmatism were 78.7% for astigmatism with-the-rule, 13.9% for astigmatism against-the-rule, 7.4% for astigmatism oblique, respectively. 4. As for the astigmatic power, the 0.50 < cylinder < 1.00dptr was 60.0%, the 1.00 < cylinder < 2.00dptr was 29.2%, and anything over the 2.00cylinder dptr was 10.8%. 5. As for the equivalent spheric power of myopic abnormal refraction eyes, the -0.50 < spheric equivalent < -2.00 diopter was 64.6%, the -2.00 < spheric equivalent < -6.00 dptr was 29.1% and anything over the -6.00 dptr was 6%. 6. The equivalent spheric power of hyperopic abnormal refraction eyes was 50% anything under 2.00diopter and 50% for anything over the 2.00diopter.

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Effect of Various Parameters on Stress Distribution around Holes in Mechanically Fastened Composite Laminates (기계적으로 체결된 복합재료 평판에서 다양한 인자의 영향에 따른 원공 주위의 응력분포)

  • Choi Jae-Min;Chun Heoung-Jae;Byun Joon-Hyung
    • Composites Research
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    • v.18 no.6
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    • pp.9-18
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    • 2005
  • With the wide applications of fiber-reinforced composite material in aero-structures and mechanical parts, the design of composite joints have become a very important research area because the joints are often the weakest areas in composite structures. This paper presents an analytical study of the stress distributions in mechanically single-fastened and multi-fastened composite laminates. The finite element models which treat the pin and hole contact problem using a contact stress analysis are described. A dimensionless stress concentration factor is used to compare the stress distributions in composite laminates quantitatively In the case of single-pin loaded composite laminate, the effects of stacking sequence, the ratio of a hole diameter and the width of a laminate (W/D ratio), the ratio of hole diameter and distance from edge to hole (E/D ratio), friction coefficient and clamping force are considered. In the case of multi-pin loaded composite laminate, the influence of the number of pins, pitch distance, number of rows, row spacing and hole pattern are considered. The results show that P/D ratio and E/D ratio affect more on stress distributions near the hole boundary than the other factors. In the case of multi-pin loaded composite laminate, the stress concentration in the double column case is better than the other cases of multi-pin loaded composite laminate.

Analysis of VTS Operators' Situational Awareness Based on In-Field Observation and Subjective Rating Methods (현장관찰법과 자기보고법에 기초한 VTS 관제사의 상황인식 분석)

  • Lee, Jae-Sik;Kim, Jung-Ho;Jang, En-Kyu
    • Journal of Navigation and Port Research
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    • v.40 no.6
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    • pp.375-384
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    • 2016
  • This study aimed to specify Vessel Traffic System(VTS) operators' situational awareness(SA) tasks and examine differences in subjective ratings for three levels of SA. Data for relative frequencies of SA tasks were collected by using direct in field observation. Subjective rating scores were obtained using a questionnaire method and compared in terms of VTS operator's gender and length of service career. The results are as follows. First, it was found that the VTS operators perform information perception task elements more frequently than those for information integration and prediction. Second, VTS operators tended to show subjectively lower evaluation scores for prediction than information perception or integration. Third, male VTS operators rated their SA ability higher than females. Fourth, the male VTS operators more than 15 years of career service showed higher subjective rating scores than those with under 5 years of service. Female VTS operators with different levels of career service showed a similar level of subjective rating scores. These results suggest that the frequency of SA related tasks and subjective SA evaluation can differ in terms of SA levels and individual differences.

창녕군 증산리 지역 강변여과수 타당성 조사 및 시험 정호 설치

  • Kim Hyeong-Su;Won Lee-Jeong;Seok Hui-Jun;Park Cheol-Suk
    • Proceedings of the Korean Society of Soil and Groundwater Environment Conference
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    • 2006.04a
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    • pp.76-81
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    • 2006
  • 창녕군 증산리 지역은 신규 취수원 확보 일환으로 강변여과 방식 취수 가능성이 한국수자원공사에 의해서 평가되고 있는 지역이다. 강변여과 방식 취수의 타당성 평가를 위해 현장 지질조사, 시추조사, 전기 비저항 탐사 및 고해상도 탄성파 탐사를 수행하였다. 또한 대상 연구지역에서의 개략적 취수 가능량 산정을 위해 모델링 평가가 수행되었으며, 개별 정호에 대한 양수량 산정을 위해 시험 정호를 설치하였다. 현장 시추 조사와 시료에 대한 입도 분석 결과, 연구 지역의 충적층 두께는 35m 전후이며, 주 대수층 구간은 지표하 $25{\sim}35m$인 것으로 추정되었다. 또한 주 대수층 구간의 수리전도도는 $10^{-2}cm/sec$ 이상으로 주로 모래섞인 자갈층으로 구성되어있는 것으로 평가되었다. 또한 전기비저항 조사 결과는 부분적으로 매우 낮은 비저항 분포 지층을 보여주고 있으며, 이는 주로 실트 및 점토로 된 지층이 부분적으로 퇴적되어 있음을 지시하며, 고해상도 탄성파 탐사 결과는 전반적으로 지하수위는 지표하부 5m 전후에 분포하고, 충적층의 하부 경계는 35 내지 45m인 것으로 해석되었다. 지하수 모델링을 통해, 취수 목표량인 180,000톤/일은 주대수층까지의 지하수위 강하 없이 확보 가능할 것으로 평가되었다. 또한 개별 정호의 산출 특성을 평가하기 위해 시험 정호를 설치하여, 실제 2,700톤/일 예비 양수 시험을 수행하였다. 예비 양수 시험 결과, 양수정에서의 수위 강하는 개략 10m, 양수정관측정에서는 약 0.3m의 수위강하만이 관찰되었으며, 양수 영향권이 수 십 m를 넘지 않을 것으로 판단되었다.서의 S97과 JBR의 세포감염 억제율은 3.85%와 3.63%로 나타났다. $textsc{k}$-casein, CU는 로타바이러스 S97과 JBR에 대해 농도 2000UM에서 97%이상의 억제효과를 나타냈으며, sialic acid는 억제효과가 거의 없었다. K-casein, GMP는 송아지뿐만 아니라 유아의 로타바이러스에 의한 설사를 억제할 수 있을 것으로 기대된다.을 향상하기 위해서는 이러한 부위에 대한 미생물 오염을 낮출 수 있는 세심한 현장 품질관리가 필요하다.en and adolescents, analysed by country, age group and gender. The paper discusses the places young consumers can turn to in trying to fulfil their growing consumer needs. It also examines how much money is at their disposal. It then concludes by considering the influence of "financial socialization" on how young people deal with money.nsumption visions based on the various perspectives, consumers are influenced in the apparel buying decision-making. Many subjects reported experiencing positive affect when imagining positive outcomes of produc

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Text integration processing based on connectives in Aphasics (실어증 환자의 접속사 정보처리에 관한 연구)

  • Kim, Soo-Jeong;Moon, Young-Sun;Kim, Mi-Ra;Kim, Yoo-Jeong;Nam, Ki-Chun
    • Annual Conference on Human and Language Technology
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    • 1999.10e
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    • pp.441-446
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    • 1999
  • 본 연구는 접속사를 통한 텍스트 통합 과정이 논리적 추론 종류에 따라 다른 정보처리 과정 혹은 다른 종류의 단원적 구조(modular structure in language processing)에 의해 처리되는지를 조사하기 위해 실시되었다. 또한, 접속사를 통한 추론 과정이 실어증의 증상 종류에 따라 다른 종류의 언어정보처리 손상이 있는지를 평가하기 위해 실시되었다. 실험에 참가한 환자는 이해성 실어증환자(Wernicke aphasic), 전반성 실어증 환자(Global aphasic), 표현성 실어증 환자(Broca aphasic) 등이었다. en 종류의 과제를 이용하였다. 한 과제는 앞 뒤 문장을 논리적 관계성을 표현하는 접속사를 채워 넣는 과제였고 다른 과제는 접속사가 포함된 텍스트가 옳은지를 판단하는 정오 판단 과제였다. 실험재료 문장에 사용된 접속사는 추가적인 정보를 제공하는 '그리고'와 대등 관계를 나타내는 '그러나' 및 인과 관계를 표현하는 '그래서' 였다. 이 세 종류의 접속사는 각기 다른 논리적 관계성을 나타낸다. 실험 결과는 실어증 환자가 전반적으로 채워 넣기 과제에서 보다는 정오 판단 과제에서 더 많은 실수를 보였으며, 표현성 실어증 환자보다는 이해성 실어증 환자가 더 많은 오류를 보였다. 또한, 세 종류의 접속사 중에 '그리고'가 표함된 텍스트에서 더 많은 실수를 보였다. 이 연구에서 나타난 흥미 있는 결과는 표현성 실어증 환자는 '그러나' 접속사가 포함된 텍스트에서의 수행이 '그래서'가 포함된 경우에서보다 좋은 반면에 전반성 실어증 환자는 '그래서'를 포함하는 텍스트에서의 수행이 '그러나'를 포함하는 텍스트에서의 수행이 더 우수해서 이중해리(double dissociation)가 나타난다는 사실이다. 이 결과는 선후 문장이 어떤 종류의 논리적 관계성을 지니는가에 따라 다른 종류의 정보처리가 진행된다는 것을 암시하는 결과이다.>$\textrm{cm}^2$.。C로 비교적 양호한 초전박막의 전기적 특성을 나타내었다.(Mg+Fe)비를 갖고 전자에 비해 Al이 풍부한 환경에서 생성되었으며, 따라서 활석과 연관되지 않은 녹니석은 생성시 광체와 인접한 화강아질 편마암에 의해 주로영향을 받았을 것으로 생각된다. 녹니석의 이러한 2가지 화학조성상의 경향은 녹니석과 공존하는 운모류나 각섬석류들의 화학분석결과와도 잘 일치한다. 이러한 결과는 이 지역의 활석 광상이 초염기성암 기원의 사문암이 열수변질작용을 받아 생성되었음을 명확하게 지시하며, 따라서 활석 광석내에 존재하는 녹니석은 활석의 근원 광물로서 녹니석편암 및 녹니석 편마암 매의 녹니석이 활석화되고 남은 잔존광물이 아니라, 주변암에 의해 성분상의 영향을 받은 열수와 사문암과의 변질교대작용에 의한 활석화과정 중에 주로 생성된 것으로 추정된다. 이러한 결과는 연구지역의 활석광상이 초염기성암의 사문암화 작용과 활석화 작용의 두 가지 변질작용에 의해 형성되어졌음을 알려준다.농도 증가 없이 폐 조직에 약 50배 정도의 고농도 cisplatin을 투여할 수 있었으며, 또한 분리 폐 관류 시 cisplatin에 의한 직접적 폐 독성은 발견되지 않았다이 낮았으나 통계학적 의의는 없었다[10.0%(4/40) : 8.2%(20/244), p>0.05]. 결론: 비디오흉강경술에서 재발을 낮추기 위해 수술시 폐야 전체를 관찰하여 존재하는 폐기포를 놓치지 않는 것이 중요하며, 폐기포를 확인하지 못한 경우와 이차성 자연기흉에 대해서는 흉막유착술에 더 세심한 주의가 필요하다는 것을 확인하였다. 비디오흉강경수술은 통증이 적고, 입원기간이 짧고, 사회로의 복귀가 빠르며, 고위험군에 적용할 수 있고, 무엇보다도 미용상의 이점이 크다는 면에서 자연기흉에 대해 유용한 치료방법임에는 틀림이 없으나 개흉술에 비해 재발율이 높고 비용이 비싸다는 문제가 제기되고 있는 만큼

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EFFECTS OF ER:YAG LASER ABLATION ON THE DENTIN (Er:YAG 레이저를 이용한 치아삭제 효과)

  • Choi, Nam-Ki;Yang, Kyu-Ho;Park, Sang-Won;Kim, Ok-Joon
    • Journal of the korean academy of Pediatric Dentistry
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    • v.28 no.4
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    • pp.683-693
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    • 2001
  • The purpose of this study was to evaluate the effects of Er:YAG laser on cutting efficacy and its histologic findings. Dentin specimens of human premolars and molars were used and irradiated by Er:YAG laser with noncontact handpiece type delivery system under different treatment condition of irradiation time. Cavity pattern and volume were evaluated to determine the cutting efficacy and following results were obtained. 1. Cutting volume of sound dentin was getting larger with time immersed in water increase 2. With the condition of irradiation (150mJ, 10Hz, 30sec), surface irregularity was more increased in sound dentin comparing to carious dentin. For the light microscopic examination, dentinal tubules were opened and ash flecks and cracks were noted with inconsistence of dentinal tubules. 3. In case of 30 sec. irradiation in carious dentin, dark zone was limited to small focus whereas 1 min. irradiation, more wider, and cracks were noted in the perpendicular to direction of dentinal tubules. For the 2 min. irradiation, cavity was the widest and more cracks were found.

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Lethal Effects of Radiation and Platinum Analogues on Multicellular Spheroids of HeLa Cells (HeLa 세포의 Spheroid에 대한 방사선과 Platinum 유사체의 치사 효과)

  • Hong, Seong-Eon
    • Radiation Oncology Journal
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    • v.7 no.2
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    • pp.149-156
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    • 1989
  • Multicellular tumor spheroids of HeLa cells have been grown in a static culture system. Samples of spheroids were exposed for 2 h to graded concentration of cis-platinum and its analogue, carboplatin, and then response assayed by survival of clonogenic cells. The purpose of present experiment is to clarify the effectiveness of these platinum compounds and to evaluate intrinsic radiosensitivity of cells using spheroids of HeLa cells as an experimental in vitro model. Variations of the drug sensitivity of monolayers as well as spheroids were also evaluated in cell-survival curves. In cis-platinum concentration-survival curve, there was a large shoulder extending as far as $Cq=3.4{\mu}M$, after which there was exponential decrease in survival curve having a Co Value of $1.2{\mu}M$ in spheroids. While the Co for the spheroids was essentially no significant change, but Cq value was larger than that of monolayers. This suggest that the effect of cis-platinum is greater En the monolayer with actively proliferaing cells than hypoxic one. In the carboplatin concentration-survival curves, the Co value of spheroids was $15.0{\mu}M$ and the ratio with the Co from monolayer cell $(32.5{\mu}M)$ was 0.40, thus indicating that the spheroids had a greater sensitivity to carboplatin than monolayers. Therefore, the effect of carboplatin is mainly on the deeper layers of spheroids acting as hypoxic cell sensitizer. The enhanced effect was obtained for monolayer cells using combined X-ray and carboplatin treatment 2 hours before irradiation. The result shown in isobologram analysis for the level of surviving fraction at 0.01 indicated that the effect of two agents was trusty supra-additive. From this experimental data, carboplatin has excited much recent interest as one of the most promising, since it is almost without nephrotoxicity and causes less gastrointestinal toxicity than cis-platinum. Interaction between carboplatin and radiation might play an important role for more effective local tumor control.

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Method of Measurement of Electromagnetic Emission from Trains (철도 차량의 전자파 방사 측정 방법)

  • Chae, Eun-Kyung;Ryu, Joon-Hyoung;Baik, Kwang-Sun;Yoon, Yong-Ki
    • Proceedings of the KSR Conference
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    • 2011.10a
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    • pp.2037-2042
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    • 2011
  • The railway electromagnetic environment is much more severe than most commercial and domestic environments. There are concerns about electromagnetic emissions from railways and their potential to interfere with the operation of commercial radio service and other equipment. EMC standards for railway applications are referenced as EN 50121 series and these standards describe the measurement method and specify limits for emission. However standard provide precise description of the general aspect of the measurement procedure and requirement of test equipments, making a reliable measurement of the radiated emissions from a train is a problem of balance between available observation time and the measurement time required by the characteristics of the measurement system. This paper focuses on the problem of measurement.

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