• Journal of Korean Institute of Industrial Engineers
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• v.24 no.2
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• pp.261-278
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• 1998

The paper represented the lower extremity muscle model as four rigid-body segments: trunk, shank, and foot. We transformed their tibial data into our shank data by rotating their tibial X and Y axes by 5.483 degrees, so the revised coordinate data used to translating the origin of their tibial reference frame to our shank reference frame. According to weight of subject, physiological cross-setional area(PCSA) of each lower extremity muscle was calculated by scaling those data by Brand. The objectives of this paper are to investigate the variations of the recruitment patterns of the lower extremity muscles, and to analyze the changes of the role assigned to each muscle during the seated foot operation. For exertion levels, the transition point of type F motor unit of each muscle is inferred by analyzing the electromyogram at the seated postures. Also, for predetermined seated foot operations exertion levels, the recruitment pattern and the changes of the role assigned are identified in the continuous exertion, by analyzing the electromyogram changes due to the accumulated muscle fatigue. This study can be used to design and to assess the pedals and foot-related equipments design.

• The Korean Journal of Physiology
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• v.23 no.1
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• pp.139-149
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• 1989

Although tail flick reflex (TFR) in rats has been used as a classic model of the nociceptive test to evaluate the action of analgesics, there have been few studies on the origin of the latent period of TFR. Present study was performed to elucidate the mechanism of increase in latency of TFR by morphine in anesthetized rats. Tail skin and dorsolateral tail nerve were stimulated electrically and EMG activities were recorded from abductor caudae dorsalis muscle participating in tail flick reflex. In the case of noxious radiant heat stimulation to tail, the tail flick tension was recorded before and after administration of morphine. Then changes in latency and conduction velocity of peripheral nerve were evaluated. The results obtained were as follows: 1) The latencies of TFR evoked by the electrical stimulation of tail skin and dorsolateral tail nerve were all within 40 ms and were elongated by several milliseconds from control after the administration of morphine. Peripheral conduction velocities of tail flick afferent nerve were within the range of 10-25 m/s. 2) The conduction velocity of peripheral nerve was significantly reduced after morphine administration, therefore the afferent time (utilization time+conduction time to spinal cord) was significantly increased. But the time for central delay and efferent time was not affected by morphine. 3) The conduction velocity under room temperature $(20-25^{\circ}C)$ was significantly reduced after morphine while that under vasodilation state $(40{\sim}42^{\circ}C)$ increased, 30 min and 45 min after morphine. The conduction velocity under vasodilation state without treatment of morphine increased continuously 4) The latency in tension response of TFR evoked by electrical stimulation was elongated by several milliseconds from control while the latency evoked by noxious radiant heat was elongated by several seconds compared with that of control. From the above results, it could be concluded that: 1) the increased latency of TFR evoked by electrical stimulation of the tail after morphine administration was due to the reducton in conduction velocity of peripheral nerve, which was the secondry effect of morphine on the peripheral vasomotion and 2) increased latency of TFR evoked by noxious radiant heat was also due to the same effect of morphine and the increase in cutaneous insulation to the noxious heat.

• Journal of Biomedical Engineering Research
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• v.22 no.1
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• pp.49-58
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• 2001

A new scale named LCL(Logically Classified Level) has been developed to judge the status of the spasticity quantitatively implementing a pcndulum test in this study. Total 30 parameters have been used to develop the new scale. One representative parameter that can represent the dominant characteristics of spasticity has been chosen through statistical analysis. 20 parameters among 30 parameters uscd in the statistical analysis were newly developed and 10 parameters were from previous studies. The new 20 parametcrs were developed using combinations of pcndulum test characteristics. ie anglc, angular velocity. musclo midel. and EMG. 11 parameters among 30 parameters have showed strong correlations each other, Finally. L11 that showed consistency at every case has been chosen to be a representative parameter among the 11 parameters. 28 patients data were separated into 4 groups. A regression equation to predict the trend of patients of L11 has been made. The paramcter L11 was tested to prove its usabilitics for various cases of patients. The new LCL scale is expected to be a quantitative scale, and to replace the MAS(Modified Ashworth Scale) that is not a quantitative scale. Especially it is also expected that the new scale could be used to plan a treatmcnt period. methods, and intensity. as it can evaluate the status of patient's in detail.

• Proceedings of the ESK Conference
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• 1997.10a
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• pp.406-413
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• 1997

근전도(EMG:Electromyogram)를 사용하여 국부 근육 피로(Localized Muscle Fatigue)를 정량화으로 분석 하기 위해 널리 이용되고 있는 AR(Autoregressive)모델의 1차 계수, RMS(Root Mean Square), ZCR(Zero Crossing Rate), MPF(Mean Power Frequency), MF(Median Frequency)를 선택하여, 근육이 발휘하는 힘과 시간의 흐름에 따라 근육 피로의 정도를 민감하게 나타내는 매개변수를 규명하였다. 피실험자 10명의 좌우 척추세움근(Erector Spinae Muscle)을 대상으로 등장수축(Sustained Isometric Contraction)조건에서 허리의 신전(Extension)운동을 실시하였다. 이때 발휘해야 하는 힘의 수준은 15%, 30%, 45%, 60%, 75% MVC 로 정하였고 각 수준마다 20초 동안 근전도를 측정하 였다. 데이터 분석은 총20초 구간의 근전도를 0.5초 간격으로 나누어 매개변수들을 각각 구하고 분석을 실시하였다. 시간의 흐름에 대한 피로도 분석 결과, AR 모델의 1차 계수와 MPF가 유의한 차이를 보였으며, 낮은 수준의 %MVC에서는 AR 계수가, 높은 수준에서는 MPF가 민감한 반응 결과를 나타냈다. 그리고 근육이 발휘하는 힘의 정도를 분석하기 위해 주로 사용되고 있는 RMS 보다는 더 AR 계수가 모든 수준에서 뚜렷하게 차이를 보인 것이 확인되었다. 따라서 AR 모델의 1차 계수가 근육의 피로 정도와 힘의 수준을 다른 매개변수에 비해 더욱 민감하게 구별함이 입증되었다. 이러한 결과는 다른 분야에서도 근육 피로를 정량적으로 측정하는데 사용될 수 있을 것으로 생각되며, 개인적 변이도를 고려한 확률 기법을 사용한다면 보다 정확한 근전도 분석이 이루어질 것으로 기대된다.있음을 알 수 있었다. 사료된다.의 결과는 자전거 에르고노미터의 결과가 트레드밀의 결과에 87.60%정도 나타났다.음을 관찰하였다. 특히 vitamin C와 E의 병용투여는 상승적으로 적용하여 간세포손상을 더욱 억제시킴을 알 수 있었다.mance and on TFP(Total Factor Productivity) growth which is a pure measure of firm performance. To utilize the advantage of panel data, FEM(Fixed Effect Model) and REM(Random Effect Model) were used. The empirical result shows that the entropy index as a measurement of inter-business relatedness is not significant but technological relatedness index is significant. OLS estimates on pooled data were considerably different from FEM or REM estimates on panel data. By introducing interaction effect among the three variables for business portfolio properties, we obtained three findings. First, only VI (Vertical integration) has a significant positive correlation with ROS. Second, when using TFP growth as an dependent variable, both TR(Technological Relatedness) and f[ are signif

• The Journal of Korean Academy of Prosthodontics
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• v.37 no.3
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• pp.328-342
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• 1999

This study was performed to investigate the factors related to tooth wear. For this study, 78 patients with temporomandibular disorders and 76 dental students without any signs and symptoms of temporomandibular disorders were selected as the patients group and as the normal group, respectively. Preferred chewing side, Angle's classification, lateral guidance pattern, head and shoulder posture were observed clinically. Electromyographic activity of anterior temporalis and masseter muscle were recorded with $BioEMG^{(R)}$ and occlusal status were recorded with $T-Scan^{(R)}$. Wear facet area of each tooth was measured from working model of upper arch corresponding to the occlusal status from T-Scan. Wear facet area were measured with planimeter in $mm^2$. Total area were divided into incisal, canine, posterior tooth area. Anterior wearfacet area was incisor area plus canine area, and unilateral area was anterior area plus posterior area. The data collected were analyzed by SAS statistical program and the results of this study were as follows: 1. There was no significant difference between the two groups in total werafacet area, and male subjects showed tendency to have larger area in the normal group but female subjects showed tendency vice versa. 2. There was no significant difference related to preferred chewing side and Angle's classification, however some difference was observed by lateral guidance pattern. Anterior wear facet area in subjects of canine guidance was the largest in the three subgroups. 3. Subjects with head tilting to right side had larger posterior and total area, and subjects with higher shoulder in right side had larger canine and anterior area than any other subgrous. 4. Electromyographic activity of masseter muscle was more correlated with wear facet area than anterior temporalis muscle, and tooth contact number and force were significantly correlated with wear facet area, but the most important factor affecting tooth attrition was age.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.37 no.4
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• pp.72-81
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• 2014

Even though two-hands lifting/lowering activity of manual materials handling tasks are prevalent at the industrial site, many manual materials handling tasks which require the worker to perform one-hand lifting/lowering are also very common at the industrial site, forestry, farming, and daily life. The objective of this study was to compare one-hand lowering activity to lifting activity in terms of biomechanical stress for the range of lowering heights from knuckle height to 10cm above floor level with two workload 7.5kg and 15.0kg. Eight male subjects with LMM were asked to perform lifting/lowering tasks using both a one-handed (left-hand and right-hand) as well as a two-handed technique. Spinal loading was estimated through an EMG-assisted free-dynamic biomechanical model. The biomechanical stress of one-hand lowering activity was shown to be 43% lower than that of one-hand lifting activity. It was claimed that the biomechanical stress for one-hand lifting/lowering activity is almost twice (194%) of the one for two-hands lifting/lowering activity. It was also found that biomechanical stress by one-hand lowering/lifting activity with the half workload of two-hands lowering/lifting activity was greater than that of the two-hands lowering/lifting activity. Therefore, it might be a risk to consider the RWL of one-hand lowering/lifting activity to simply be a half of the RWL of two-hands lowering/lifting activity recommended by NIOSH.

• Journal of the Ergonomics Society of Korea
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• v.30 no.5
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• pp.597-603
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• 2011

Objective: The objective of this study was to compare one-hand and two-hands lifting activity in terms of biomechanical stress for the range of lifting heights from 10cm above floor level to knuckle height. Background: Even though two-hands lifting activity of manual materials handling tasks are prevalent at the industrial site, many manual materials handling tasks which require the worker to perform one-hand lifting are also very common at the industrial site and forestry and farming. Method: Eight male subjects were asked to perform lifting tasks using both a one-handed as well as a two-handed lifting technique. Trunk muscle electromyographic activity was recorded while the subjects performed the lifting tasks. This information was used as input to an EMG-assisted free-dynamic biomechanical model that predicted spinal loading in three dimensions. Results: It was shown that for the left-hand lifting tasks, the values of moment, lateral shear force, A-P shear force, and compressive force were increased by the average 43%, as the workload was increased twice from 7.5kg to 15.0kg. For the right-hand lifting task, these were increased by the average 34%. For the two-hands lifting tasks, these were increased by the average 25%. The lateral shear forces at L5/S1 of one-hand lifting tasks, notwithstanding the half of the workload of two-hands lifting tasks, were very high in the 300~317% of the one of two-hands lifting tasks. The moments at L5/S1 of one-hand lifting tasks were 126~166% of the one of two-hands lifting tasks. Conclusion: It is concluded that the effect of workload for one-hand lifting is greater than two-hands lifting. It can also be concluded that asymmetrical effect of one-hand lifting is much greater than workload effect. Application: The results of this study can be used to provide guidelines of recommended safe weights for tasks involved in one-hand lifting activity.

• Journal of the Ergonomics Society of Korea
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• v.32 no.5
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• pp.413-420
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• 2013

Objective: The objective of this study was to compare one-hand and two-hands lowering activity in terms of biomechanical stress for the range of lowering heights from knuckle height to 10cm above floor level. Background: Even though two-hands lifting/lowering activity of manual materials handling tasks are prevalent at the industrial site, many manual materials handling tasks which require the worker to perform one-hand lifting/lowering are also very common at the industrial site and forestry and farming. Method: Eight male subjects were asked to perform lowering tasks using both a one-handed as well as a two-handed lowering technique. Trunk muscle electromyographic activity was recorded while the subjects performed the lowering tasks. This information was used as input to an EMG-assisted free-dynamic biomechanical model that predicted spinal loading in three dimensions. Results: It was shown that for the left-hand lowering tasks, the values of moment, lateral shear force, A-P shear force, and compressive force were increased by the average 6%, as the workload was increased twice from 7.5kg to 15kg. For the right-hand lowering task, these were increased by the average 17%. For the two-hands lowering tasks, these were increased by the average 14%. Conclusion: Even though the effect of workload on the biomechanical stress for both one-hand and two-hands lowering tasks is not so significant for the workload less than 15kg, it can be claimed that the biomechanical stress for one-hand lowering is greater than for two-hands lowering tasks. Therefore, it can be concluded that asymmetrical lowering posture would give greater influence on the biomechanical stress than the workload effect for one-hand lowering activity. Application: The result of this study may be used to provide guidelines of recommended safe weights for tasks involved in one-hand lowering activity.

• Journal of the Korean Society of Physical Medicine
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• v.5 no.2
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• pp.223-231
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• 2010

Purpose : The Purpose of this study was to compare muscle activation and foot pressure on baby carrier and sling for baby care. Methods : Thirty one women subjects (mean age 23.2 years) participated in four static conditions : unloaded quite standing, carrying an anterior baby carrier, carrying a posterior baby carrier, and sling. The baby carrier and sling were loaded with baby model that filled 7.6kg loads. Surface electromyography was used to measure activity in the internal oblique, T4, L3, L5 paraspinal muscle, vastus medialis, biceps femoris, tibialis anterior, and gastrocnemius for four conditions. And foot pressure was measured by using MatScan system(Tekscan, USA). Results : The activation of Biceps femoris, T4, L3, and L5 paraspinal muscle were significant differences(p<.05), but other muscles were no significant differences in four conditions(p>.05). Right foot contact area and peak pressure of right mid foot area were significant differences in four conditions(p<.05). Conclusion : The results of this study indicate that the use of baby carrier of sling for baby care were influenced postural responses of young women. Further work is recommended to find out the influences of various assistive devices for baby care.

• Biomolecules & Therapeutics
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• v.27 no.6
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• pp.584-590
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• 2019

Luteolin, a widespread flavonoid, has been known to have neuroprotective activity against various neurologic diseases such as epilepsy, and Alzheimer's disease. However, little information is available regarding the hypnotic effect of luteolin. In this study, we evaluated the hypnotic effect of luteolin and its underlying mechanism. In pentobarbital-induced sleeping mice model, luteolin (1, and 3 mg/kg, p.o.) decreased sleep latency and increased the total sleep time. Through electroencephalogram (EEG) and electromyogram (EMG) recording, we demonstrated that luteolin increased non-rapid eye movement (NREM) sleep time and decreased wake time. To evaluate the underlying mechanism, we examined the effects of various pharmacological antagonists on the hypnotic effect of luteolin. The hypnotic effect of 3 mg/kg of luteolin was not affected by flumazenil, a GABAA receptorbenzodiazepine (GABAAR-BDZ) binding site antagonist, and bicuculine, a GABAAR-GABA binding site antagonist. On the other hand, the hypnotic effect of 3 mg/kg of luteolin was almost completely blocked by caffeine, an antagonist for both adenosine A1 and A2A receptor (A1R and A2AR), 8-Cyclopentyl-1,3-dipropylxanthine (DPCPX), an A1R antagonist, and SCH-58261, an A2AR antagonist. From the binding affinity assay, we have found that luteolin significantly binds to not only A1R but also A2AR with $IC_{50}$ of 1.19, $0.84{\mu}g/kg$, respectively. However, luteolin did not bind to either BDZ-receptor or GABAAR. From these results, it has been suggested that luteolin has hypnotic efficacy through A1R and A2AR binding.