• Title/Summary/Keyword: EI24

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A Facile One-pot Synthesis of Fused 2-Thiouracils: Dipyrimidinopyridine, Pyrazolopyrimidine and Pyridazinopyrimidines

  • Youssif, Shaker;EI-Bahaie, Said;Nabih, Esam
    • Bulletin of the Korean Chemical Society
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    • v.24 no.10
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    • pp.1429-1432
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    • 2003
  • A novel fused thiouracil containing a heterocyclic ring system, dipyrimidinopyridine (3), has been prepared through the cyclization of compound 2. Compound 2 was formed by the formylation of 6-amino-2-thiouracil 1, pyrazolopyrimidines 8-10 via the heating of 6-arylhydrazono-2-thiouracils 5-7, compound 11, using Vilsmeier reagent with compound 4, pyrazolylpyrimidine 12, indolodiazinopyrimidine 14 and pyridazinopyrimidine 15. Pyridazino-pyrimidine 15 was formed by the condensation of compound 4 with acetylacetone, isatin and benzyl, respectively.

Evaluation of SWAT Prediction Error according to Accuracy of Land Cover Map (토지피복도 정확도에 따른 SWAT 예측 오류 평가)

  • Heo, Sunggu;Kim, Kisung;Kim, Namwon;Ahn, Jaehun;Park, Sanghun;Yoo, Dongseon;Choi, JoongDae;Lim, Kyoungjae
    • Journal of Korean Society on Water Environment
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    • v.24 no.6
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    • pp.690-700
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    • 2008
  • The Soil and Water Assessment Tool (SWAT) model users tend to use the readily available input dataset, such as the Ministry of Environment (MOE) land cover data ignoring temporal and spatial changes in land cover. The SWAT model was calibrated and validated with this land cover data. The EI values were 0.79 and 0.85 for streamflow calibration and validation, respectively. The EI were 0.79 and 0.86 for sediment calibration and validation, respectively. With newly prepared landcover dataset for the Doam-dam watershed, the SWAT model better predicts hydrologic and sediment behaviors. The number of HRUs with new land cover data increased by 70.2% compared with that with the MOE land cover, indicating better representation of small-sized agricultural field boundaries. The SWAT estimated annual average sediment yield with the MOE land cover data was 61.8 ton/ha/year for the Doam-dam watershed, while 36.2 ton/ha/year (70.7% difference) of annual sediment yield with new land cover data. Especially the most significant difference in estimated sediment yield was 548.0% for the subwatershed #2. Therefore it is recommended that one needs to carefully validate land cover for the study watershed for accurate hydrologic and sediment simulation with the SWAT model.

Water Quality Assessment at Coastal Area of the East Sea of Korea (한국 동해연안의 수질 평가)

  • Kim, Young-Sug;Lee, Yong-Hwa;Choi, Hee-Gu
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.18 no.1
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    • pp.15-24
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    • 2012
  • This study aims to investigate characteristics of water quality factors by using survey results of national marine environmental monitoring system from 2004 to 2010 at coastal area of the East Sea of Korea. In this study, we chose statistical methods to analyze the correlation among water quality parameters and principal component analysis for characteristics of each water environment. In addition to this, we evaluated each water's pollution level based on eutrophication standard of OECD, Eutrophication Index(EI), and Organic Pollution Index(OPI). Major factors were chlorophyll a and salt according to the analysis at coastal area of the East Sea. The sea was divided into the south and the central part by Jukbyeon. Also, Jukbyeon in the central part of the East Sea and Gampo in the southern sea coastal waters have been classified separately. The nutritional status of coastal area of East Sea presented Mesotrophic to Oligotrophic level and EI showed less than 1. OPI in all of the coastal area at the East Sea represented that the water quality condition was favorable.

Evaluation of Effects of Soil Erosion Estimation Accuracy on Sediment Yield with SATEEC L Module (SATEEC L모듈을 이용하여 토양유실량 산정 정확성이 유사량 예측에 미치는 영향 평가)

  • Woo, Won-Hee;Jang, Won-Seok;Kim, Ik-Jae;Kim, Ki-Sung;Ok, Yong-Sik;Kim, Nam-Won;Jeon, Ji-Hong;Lim, Kyoung-Jae
    • Journal of The Korean Society of Agricultural Engineers
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    • v.53 no.2
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    • pp.19-26
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    • 2011
  • SATEEC ArcView GIS system was developed using the Universal Soil Loss Equation (USLE) and sediment delivery ratio (SDR) modules. In addition, time-variant R and C modules and $R_5$ module were developed and integrated into the SATEEC system in recent years. The SATEEC ArcView GIS 2.1 system is a simple-to-use system which can estimate soil erosion and sediment yield spatially and temporarily using only USLE input data, DEM, and daily rainfall dataset. In this study, the SATEEC 2.1 system was used to evaluate the effects of USLE LS input data considering slope length segmentation on soil erosion and sediment yield estimation. Use of USLE LS with slope length segmentation due to roads in the watershed, soil erosion estimation decreased by 24.70 %. However, the estimated sediment yield using SATEEC GA-SDR matched measured sediment values in both scenarios (EI values of 0.650 and EI 0.651 w/o and w/flow segmentation). This is because the SATEEC GA-SDR module estimates lower SDR in case of greater soil erosion estimation (without flow length segmentation) and greater SDR in case of lower soil erosion estimation (with flow length segmentation). This indicates that the SATEEC soil erosion need to be estimated with care for accurate estimation of SDR at a watershed scale and for accurate evaluation of BMPs in the watershed.

Analysis of Soil Erosion Reduction Ratio with Changes in Soil Reconditioning Amount for Highland Agricultural Crops (고랭지 농업의 작물별 객토량 변화에 따른 토양유실 저감 분석)

  • Heo, Sunggu;Jun, ManSig;Park, Sanghun;Kim, Ki-sung;Kang, SungKeun;Ok, YongSik;Lim, Kyoung Jae
    • Journal of Korean Society on Water Environment
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    • v.24 no.2
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    • pp.185-194
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    • 2008
  • There is increased soil erosion potential at highland agricultural crop fields because of its topographic characteristics and site-specific agricultural management practices performed at these areas. The agricultural upland fields are usually located at the sloping areas, resulting in higher soil loss, pesticides, and nutrients in case of torrential rainfall events or typhoon, such as 2002 Rusa and 2003 MaeMi. At the highland agricultural fields, the soil reconditioning have been performed every year to decrease damage by continuous cropping and pests. Also it has been done to increase crop productivity and soil fertility. The increased amounts of soil used for soil reconditioning are increasing over the years, causing significant impacts on water quality at the receiving water bodies. In this study, the field investigation was done to check soil reconditioning status for potato, carrot, and cabbage at the Doam-dam watershed. With these data obtained from the field investigation, the Soil and Water Assesment Tool (SWAT) model was used to simulate the soil loss reduction with environment-friendly and agronomically enough soil reconditioning. The average soil reconditioning depth for potato was 34.3 cm, 48.3 cm for carrot, and 31.2 cm for cabbage at the Doam-dam watershed. These data were used for SWAT model runs. Before the SWAT simulation, the SWAT ArcView GIS Patch, developed by the Kangwon National University, was applied because of proper simulation of soil erosion and sediment yield at the sloping watershed, such as the Doam-dam watershed. With this patch applied, the Coefficient of Determination ($R^2$) value was 0.85 and the Nash-Sutcliffe Model Efficiency (EI) was 0.75 for flow calibration. The $R^2$ value was 0.87 and the EI was 0.85 for flow validation. For sediment simulation, the $R^2$ value was 0.91 and the EI was 0.70, indicating the SWAT model predicts the soil erosion processes and sediment yield at the Doam-dam watershed. With the calibrated and validated SWAT for the Doam-dam watershed, the soil erosion reduction was investigated for potato, carrot, and cabbage. For potato, around 19.3 cm of soil were over applied to the agricultural field, causing 146% of more soil erosion rate, approximately 33.3 cm, causing 146% of more soil erosion for carrot, and approximately 16.2 cm, causing 44% of more soil erosion. The results obtained in this study showed that excessive soil reconditioning are performed at the highland agricultural fields, causing severe muddy water issues and water quality degradation at the Doam-water watershed. The results can be used to develop soil reconditioning standard policy for various crops at the highland agricultural fields, without causing problems agronomically and environmentally.

Changes of Fruit Characteristics and Cell Wall Component during Maturation and Ripening in Asian Pear 'Hanareum', 'Manpungbae', and 'Niitaka' (Pyrus pyrifolia Nakai) ('한아름', '만풍배' 및 '신고' 배의 성숙 기간 중 과실특성 및 세포벽 관련물질의 변화)

  • Vu, Thi Kim Oanh;Lee, Ug-Yong;Choi, Jin-Ho;Lee, Han-Chan;Chun, Jong-Pil
    • Horticultural Science & Technology
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    • v.30 no.4
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    • pp.345-356
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    • 2012
  • We investigated the changes of fruit quality parameters, polysaccharide contents and cell wall components during maturation and ripening of two Korean pear cultivar 'Hanareum' and 'Manpungbae' compared with 'Niitaka' pear (Pyrus pyrifolia Nakai) which showed different physiological maturity based on days after full bloom (DAFB). Flesh firmness decreased continuously with fruit development and maturation, reaching a final level of 29.4, 33.5, and 27.4N at maturity in 'Hanareum' (127 DAFB), 'Manpungbae' (163 DAFB), and 'Niitaka' (170 DAFB), respectively. The level of ethylene production was very low in early season 'Hanareum' pear which showed at most 0.39 ${\mu}L{\cdot}L^{-1}$ at maturity and no ethylene was detected in 'Manpungbae' and 'Niitaka' at maturity. Fructose was the most abundant soluble sugar during fruit maturation in the pears tested and an increase of sucrose was observed during fruit ripening in the Asian pears commonly. Ethanol insoluble solids (EIS) content decreased gradually with different levels among the pear cultivars as fruit ripens consisted of 10.79, 12.72, and 12.75 $mg{\cdot}g^{-1}$ FW. The amount of total soluble polyuronides was higher in early season cultivars 'Hanareum' than those of mid-season cultivar 'Manpungbae' and 'Niitaka'. In 'Niitaka' which harvested most late season, the level of 4% KOH soluble hemicelluloses was lower than 'Hanareum' and 'Manpungbae' and maintained constantly during fruit ripening period. Cellulosic residues were determined high level in 'Niitaka' which showed 612.33 ${\mu}g{\cdot}mg^{-1}$ EIS at maturity when compared with 'Hanareum' (408.0 ${\mu}g{\cdot}mg^{-1}$ EIS) and 'Manpungbae' (538.67 ${\mu}g{\cdot}mg^{-1}$ EIS). The main constituents of cell wall neutral sugars which consisted of arabinose, xylose, galactose, and glucose were decreased gradually with onset of fruit ripening regardless of cultivar. Arabinose which was predominant in 'Hanareum' pear decreased at the last stage of ripening, but the changes of cell wall neutral sugar during ripening were not occurred in 'Niitaka' pear. The change of molecular mass distribution in water soluble pectin observed dominantly at the early stage of fruit development. Depolymerization of 4% KOH-soluble hemicelluloses and degradation of xyloglucan showed in early-season cultivar 'Hanareum' during fruit maturation, and degradation of those fractions were detected only at the early stage fruit development in mid-season cultivar 'Manpungbae' and 'Niitaka'. The molecular mass profile of CDTA soluble pectin, $Na_2CO_3$-SP and 24% KOH soluble hemicelluloses showed no significant change during fruit maturation regardless of cultivar.

Insects Diversity in Urban Green Space (도시 녹지공간의 곤충다양성)

  • Park, Seong-Joon;Lee, Min-Ho;Kim, Jae-Won;Hong, Yong-Sik;Kim, Do-Sung
    • Korean Journal of Environment and Ecology
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    • v.29 no.3
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    • pp.374-390
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    • 2015
  • This study aimed to identify the insect diversity and forest in urban green space, which can determine the current status of the ecosystem and provide basic data and information required for conservation planning and sustainable use of the environment. For this study, we have surveyed insect diversity by habitat types in the botanic garden of Wonkwang University, Iksan, from September, 2010 to September, 2011. During the research period, a total of 209 species, 78 families and 10 orders were observed, including 10 exportable species, 1 species of Korean Red List, 2 climate-sensitive indicator species and 70 designated species. Among these taxonomic groups, Coleoptera (36.36 %) showed the highest diversity with 76 species, followed by Hemiptera (25.36 %) with 46 species, Diptera (11.48 %) with 24 species and Hymenoptera (7.66 %) with 16 species. As for the diversity by survey time, the largest number of species were observed in September 2010 (52 families, 105 species), followed by May 2011 (37 families, 87 species), July 2011 (50 families, 86 species), June 2011 (40 families, 80 species) and August 2011 (43 families, 73 species). Relatively low diversity was observed in September 2011 (38 families, 60 species), October 2010 (36 families, 52 species) and April 2011 (19 families, 29 species). As for the diversity by survey point, the highest diversity was observed in S4 (75 families, 186 species, 88.99 %), followed by S1 (41 families, 70 species, 33.49 %), S2 (41 families, 63 species, 30.14 %), and S3 (36 families, 59 species, 28.22 %). According to the community analysis, the survey area S4 (H'=3.344, RI=9.257) showed the highest numbers in diversity index (H') and richness index (RI) of insects and S1 (0.985) showed the highest species evenness index (EI). On the other hand, S3 showed the lowest numbers (H'=2.428, RI=4.307, EI=0.832) in every index. The insect fauna is closely associated with the plants and vegetation structure in the green space. Therefore, it is necessary to manage and maintain the urban green space to make it similar to the natural environment.

A 3D User Interface for Mobile SNS Applications (모바일 소셜 네트워크 서비스 응용프로그램을 위한 3D 사용자 인터페이스)

  • Jeong, Han-Gil;Jeon, Jae-Woong;Sohn, Ei-Sung;Choy, Yoon-Chul
    • Proceedings of the Korean Information Science Society Conference
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    • 2012.06d
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    • pp.24-26
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    • 2012
  • 오늘날 전 세계적으로 스마트폰 사용자가 증가하면서 SNS(Social Network Service)를 활용한 어플리케이션의 이용이 더욱 보편화 되고 있는 추세이다. 이에 따라 모바일 환경의 SNS 어플리케이션에 맞는 사용자 인터페이스에 대한 수요 역시 증가하고 있다. 따라서 본 논문에서는 SNS 어플리케이션에 적용할 수 있는 사용자에게 더 높은 몰입감과 편의성을 제공하기 위한 직관적인 3D 사용자 인터페이스를 제안한다. 제안하는 시스템은 Facebook Open API를 기반으로 소셜 네트워크 구성원의 프로필 사진을 3D 방식으로 배치하는 인터페이스 기법과 효과를 구현하며, 이를 통해 사용자의 SNS 어플리케이션 사용성을 제고한다.

Urinary Metabolism and Excretion of Carbinoxamine after Oral Administration to Man

  • Jung, Byung-Hwa;Chung, Bong-Chul;Park, Jong-Sei
    • Biomolecules & Therapeutics
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    • v.4 no.3
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    • pp.251-256
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    • 1996
  • The metabolism of carbinoxamine, 2-[(4-chlorophenyl)-2-pyridinyl-methoxy]-N, N-dimethylethaneamine, was studied in adult male volunteers after an oral dose of 15 mg. Solvent extracts of urine obtained with or without enzyme hydrolysis were analyzed by gas chromatography-mass spectrometry after derivatization with MSTFA/TMSCl (N-methyl-N-trimethylsilyltrifluoroacetamide/trimethyl chlorosilane). The structures of metabolites were determined based on the electron impact (EI) and chemical ionization (CI) mass spectra. Nonconjugated metabolites identified in the urine were carbinoxamine, nor-carbinoxamine, and bits-nor-carbinoxamine. Parent drug, nor-carbinoxamine, and bits-nor-carbinoxamine were also detected as conjugated forms. These metabolites observed in human urine were different from those previously reported in the rat. Urinary excretions of carbinoxamine were reached to maxima in 4 hours after drug administration with 4.9%-8.1% and 2.5-4.2% of the dose excreted during 24 h as carbinoxamine and its glucuronide, respectively.

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Aspergillus candidusF1484 균주가 생산하는 항진균 화합물의 분리 및 특성

  • Kim, Sung-Uk;Lee, So-Young;Kim, Sung-Kyu;Son, Kwang-Hee;Kim, Young-Kook;Moon, Surk-Sik;Bok, Song-Hae
    • Microbiology and Biotechnology Letters
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    • v.24 no.5
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    • pp.574-578
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    • 1996
  • In the course of screening for the antifungal compounds against Candida albicans, an antifungal compound (F1480) was isolated from the culture broth of Aspergillus candidus F1484. Isolation and purification of compound F1484 were performed using ethyl acetate extraction, silica gel column chromatography, ODS column chromatography, and preparative HPLC. The structure of compound F1484 was determined by the spectroscopic analyses of EI-MS, $^{13}$C, $^{1}$H-NMR, DEPT, HMQC, and HMBC. This compound appeared to have a structure of antifungal agent, chloroflavonin. In addition to antifungal activities against the yeast phase of Candida species, compound F1484 showed cytotoxic effect against various human tumor cell lines.

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