• 한국멀티미디어학회논문지
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• 제19권4호
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• pp.756-764
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• 2016

In this paper, we present electroencephalography (EEG)-based power spectra analysis and auditory stimuli methods as coping mechanisms for disgust affection and phobia. Disgust affection is a negative emotion generated from trying to eliminate something harmful to one. It is usually related to mental illnesses such as obsessive-compulsive disorder, specifically phobia and depression. In our experiments, participants watched videos on horrible body mutilation and disgusting creatures, with either the original sound track or relaxing and exciting music as auditory stimulation. After watching the videos with original sound track, the participants watched the same video with a different audio background, such as soothing or cheerful music. We analyzed the EEG data utilizing relative power spectra and examined survey results of the participants. The results demonstrated that disgust affection is decreased when participants watched the video with relaxing or exciting music instead of the original soundtracks. Moreover, we confirmed that human's brainwave reacts according to types of audio and sources of disgust affection.

• The Korean Journal of Physiology and Pharmacology
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• 제3권3호
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• pp.245-250
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• 1999

The effects of an antipsychotic, chlorpromazine, on the electroencephalogram (EEG) were observed while rats were awake but immobile. The time course and the dose-dependency of the EEG changes were examined. The method of the power spectrum analysis was used to examine the EEG changes by the drug. The bands were divided into delta $(1{\sim}3.5\;Hz),$ theta $(3.5{\sim}8\;Hz),$ alpha $(8{\sim}13\;Hz),$ beta1 $(13{\sim}21\;Hz),$ beta2 $(21{\sim}30\;Hz)$ and gamma $(30{\sim}50\;Hz).$ In rats, the low dose of chlropromazine (1 mg/kg, i.p.) produced a significant increase in the power of the beta1 band. The higher doses (5, 10 mg/kg, i.p.) produced a significant increase in the power of the delta, theta, alpha and beta1 bands, and the decrease in the power of the gamma band. The powers of the bands changed dose-dependently. Then, the authors discussed whether the EEG effects produced by a drug are associated with the accompanying behavioral changes specifically.

• 대한임상검사과학회지
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• 제47권1호
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• pp.46-50
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• 2015

The previous studies showed that the visual imagery activated the occipital and posterior inferior temporal area of the brain, and the damage to the occipital cortex impaired the visual mental imagery. We studied current-source distribution of electroencephalography (EEG) to observe neuronal activity during imagery tennis playing. Eleven healthy volunteers were enrolled. All volunteers were right-handed males and novices for tennis playing. The mean age of them was 24.9 years. The EEGs were recorded on the scalp electrodes located according to the International 10~20 System. The number of electrodes was 25 channels including subtemporal electrodes. The EEG recording session was 13 min including 5 segments: resting-I, scenery-slide show, resting-II, watching tennis-game video, and imagery-tennis playing. The recoding durations were 3, 2, 3, 2, and 3 min respectively. Five 'artifact free 3-sec segments' were selected in each segment of 'imagery-tennis playing' and 'resting-II'. We did the frequency domain analysis with the EEG segments using a distributed model of current-source analysis. The statistical-nonparametric maps (SnPMs) were obtained between the segments of 'imagery-tennis playing' and the segments of 'resting-II' (p<0.01). The significant change of current-source density was observed only in alpha-2 frequency band (10~12 Hz). The current-sourcedensity was increased in the hippocampus, parahippocampus, and occipital fusiform gyrus in the right cerebral hemisphere (p<0.01). Imaginary-tennis playing may activate the hippocampal-occipital alpha networks of nondominant hemisphere.

• Psychiatry investigation
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• 제15권11호
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• pp.1087-1093
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• 2018

Objective Posttraumatic stress disorder (PTSD) is distinct from anxiety disorders in its etiology and clinical symptomatology, and was reclassified into trauma- and stressor-related disorders in DSM-5. This study aimed to find neurophysiological correlates differentiating PTSD from anxiety disorders using resting-state quantitative electroencephalography (qEEG). Methods Thirty-six patients with either PTSD or acute stress disorder and 79 patients with anxiety disorder were included in the analysis. qEEG data of absolute and relative powers and patients' medication status on the day of qEEG examination were obtained. Electrodes were grouped into frontal, central, and posterior regions to analyze for regional differences. General linear models were utilized to test for group differences in absolute and relative powers while controlling for medications. Results PTSD patients differed from those with anxiety disorders in overall absolute powers [F(5,327)=2.601, p=0.025]. Specifically, overall absolute delta powers [F(1,331)=4.363, p=0.037], and overall relative gamma powers [F(1,331)=3.965, p=0.047] were increased in PTSD group compared to anxiety disorder group. Post hoc analysis regarding brain regions showed that the increase in absolute delta powers were localized to the posterior region [F(1,107)=4.001, p=0.048]. Additionally, frontal absolute gamma powers [F(1,107)=4.138, p=0.044] were increased in PTSD group compared to anxiety disorder group. Conclusion Our study suggests increased overall absolute delta powers and relative gamma powers as potential markers that could differentiate PTSD from anxiety disorders. Moreover, increased frontal absolute gamma and posterior delta powers might pose as novel markers of PTSD, which may reflect its distinct symptomatology.

• 감성과학
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• 제11권3호
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• pp.357-364
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• 2008

본 연구에서는 반복적인 동작 행위에 따른 뇌파의 훈련효과를 규명하고자 한다. 훈련 효과를 검증하기 위해 반복적인 동작시의 뇌파 출현량 및 EMG와 EEG의 coherence의 변화를 분석하였다. 피실험자는 5명으로 실험 시간은 총 48분이며, 반복 일에 대한 훈련 효과를 살펴보기 위해 5일간 진행하였다. 반복적인 동작은 손을 오므렸다 폈다 하는 행위로, 5초간의 동작실행과 10초간의 휴식시간으로 나눠 실험하였다. 동작 유무와 반복 일에 따른 뮤파와 베타파량의 차이를 살펴 본 결과, 반복시간에 따라 뮤파 및 베타파량이 증가되는 경향이 있었다. 그러나 5일 동안의 반복 일에 따른 훈련효과는 보이지 않았다. 또한 EMG와 EEG의 coherence는 반복 시간과 반복 일에 대한 훈련 효과를 확인할 수 없었다.

• The Korean Journal of Physiology and Pharmacology
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• 제28권3호
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• pp.253-264
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• 2024

Chronic neuropathic pain (CNP) is a complex condition often arising from neural maladaptation after nerve injury. Understanding CNP complications involves the intricate interplay between brain-heart dynamics, assessed through quantitative electroencephalogram (qEEG) and heart rate variability (HRV). However, insights into their interaction in chronic pain are limited. Resting EEG and simultaneous electrocardiogram (lead II) of the participants were recorded for qEEG and HRV analysis. Correlations between HRV and qEEG parameters were calculated and compared with age, sex, and body mass index (BMI)-matched controls. CNP patients showed reduced HRV and significant increases in qEEG power spectral densities within delta, theta, and beta frequency ranges. A positive correlation was found between low frequency/high frequency (LF/HF) ratio in HRV analysis and theta, alpha, and beta frequency bands in qEEG among CNP patients. However, no significant correlation was observed between parasympathetic indices and theta, beta bands in qEEG within CNP group, unlike age, sex, and BMI-matched healthy controls. CNP patients display significant HRV reductions and distinctive qEEG patterns. While healthy controls exhibit significant correlations between parasympathetic HRV parameters and qEEG spectral densities, these relationships are diminished or absent in CNP individuals. LF/HF ratio, reflecting sympathovagal balance, correlates significantly with qEEG frequency bands (theta, alpha, beta), illuminating autonomic dysregulation in CNP. These findings emphasize the intricate brain-heart interplay in chronic pain, warranting further exploration.

• Annals of Clinical Neurophysiology
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• 제2권2호
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• pp.119-124
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• 2000

Background : We studied EEG changes during pilocarpine-induced status epilepticus(SE), a widely used model whose EEG characteristics have not been fully described previously. Methods : Male Sprague-Dawley rats weighing 250-350 grams were used as subjects. SE was induced 5-7 days after placement of chronic epidural electrodes, using 360-380 mg/Kg pilocarpine IP. Rats were observed with continuous EEG recording following pilocarpine injection until end of the SE episode. Results : SE occurred in 10/12 rats studied. SE began with a series of discrete seizures $11.1{\pm}3.93$ minutes after pilocarpine injection. $5.2{\pm}2.71$ seizures occurred over $10.9{\pm}4.62$ minutes, until the EEG converted to a waxing and waning pattern, during which the amplitude and frequency of epileptiform activity increased. After $1.4{\pm}1.82$ minutes, a pattern of continuous high amplitude rapid spiking was established. Continuous spiking continued for $3.4{\pm}0.48$ hours with a very gradual decline in amplitude and frequency, until periodic epileptiform discharges(PEDs) began to occur. The EEG consisted primarily of PEDs for another $7.4{\pm}3.09$ hours, until electrographic generalized seizures began to occur. These continued for $5.8{\pm}4.82$ hours until death. Duration of SE was $17.0{\pm}5.88$ hours. Flat periods were a prominent feature during all EEG patterns in this model. Conclusion : EEG features distinctive in pilocarpine SE(but not unique to it) include flat periods during all patterns and resumption of continuous spiking episodes after the onset of PEDs. The sequence of discrete seizures to waxing and waning to continuous spiking to PEDs was identical to that which has been described in humans and other animal models.

• 한국정보통신학회:학술대회논문집
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• 한국정보통신학회 2016년도 춘계학술대회
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• pp.513-514
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• 2016

최근 뇌파에 대한 연구가 아주 활발하게 진행되고 있다. 이러한 뇌파를 분석하기 위해서는 뇌파센서를 이용하여 뇌파를 수집하고 뇌파의 주파수 분석 등을 이용하여 뇌파를 분석할 수 있다. 이러한 분석을 위하여 본 논문에서는 NeuroSky 사의 mindwave mobile 뇌파 센서를 이용하여 뇌파를 수집하고 수집된 뇌파의 주파수 분석을 이용하여 delta, theta, alpha, SMR, beta 파를 분석하고 이러한 주파수별 뇌파가 집중도와 어떤 상관관계를 갖고 있는지 분석하고자 한다. 이러한 분석을 통하여 일반적으로 알려진 집중도와 beta파의 밀접한 관계뿐만 아니라 다른 주파수 성분과의 상관관계도 분석할 수 있을 것이다. 이러한 기초연구를 통하여 보다 발전된 형태의 뇌파를 연구할 수 있을 것이다.

• 한국정보과학회논문지:소프트웨어및응용
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• 제27권1호
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• pp.24-32
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• 2000

인간의 생각만으로 기계를 작동할 수 있게 하는 인터페이스 시스템에 관한 연구 분야인 BCI (Brain-Computer Interface)에서는 피험자의 두피로부터 EEG(Electroencephalograph)를 측정하고 인식하여 뇌 상태를 알아내고 그 결과를 기계의 조종에 응용하는 방법을 사용한다. 본 연구에서는 각 개인으로부터 고유의 뇌파인 EEG를 얻고 신호처리하여 인식하는 인식모델을 제안하였다. 제안된 모델은 특정 작업을 수행하고 있을 때의 EEG 신호로부터 인식에 중요한 영향을 미치는 특징들을 추출해 내고, 이를 인식에 이용한다. 제안된 모델은 인식할 EEG 패턴들을 두개씩 분류하여 각각을 인식한 후, 그 결과를 종합하여 최종적인 인식결과를 얻도록 하였다. 본 연구의 실험에서는 피험자가 4가지의 작업을 수행하는 동안 얻어지는 4가지 EEG 패턴을 인식하였다. 제안된 모델은 90%이상의 높은 인식율을 보였고, 각 피험자에게 독특하게 존재하는 특징들을 인식 결과로서 제공하였다. 제안된 모델의 높은 인식율과 빠른 처리속도는 실시간 BCI 시스템에 응용될 수 있는 가능성을 보여주고 있다.

• 한국정보과학회:학술대회논문집
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• 한국정보과학회 2012년도 한국컴퓨터종합학술대회논문집 Vol.39 No.1(B)
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• pp.414-416
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• 2012

고차 주성분 방법으로는 텐서 분석이 있었다. Electroencephalography(EEG) 데이터나 Social Network 데이터에 텐서 분석이 적용되어 주요한 성분들을 찾는 연구들이 있었다. 그러나 텐서 분석은 직관적으로 이해하기에 어려움이 있으며 중요한 노드를 찾는데에는 다소 어려움이 있다. 본 논문에서는 고차 하이퍼에지로 이차원 행렬을 만들고 주성분분석법을 이용하여 중요한 노드를 찾는 새로운 방법론을 제시한다. 데이터로는 Multimodal Memory Game(MMG) 수행시 촬영한 EEG 데이터를 사용하였다. MMG는 TV 드라마 기반의 기억인출게임이다. 베타파의 Power Spectrum Density(PSD)는 각 위치의 채널들의 활성도를 나타내는 지표이다. 우리는 Random Sampling을 바탕으로 PSD 상위 50%의 채널들간의 전이행렬을 구하였다. 그 후 고유치와 고유벡터를 구하였다. 가장 큰 고유치의 고유벡터는 주성분을 나타내며 고유벡터의 각 원소들은 중요도를 나타내는 centrality 이다. 세 명의 피험자에 대한 centrality 상위 30개의 중요한 채널들을 구하였고 세명에 공통적으로 포함되는 채널을 확인하였다.