• Title/Summary/Keyword: EC performance

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Association of Serum HE4 with Primary Tumor Diameter and Depth of Myometrial Invasion in Endometrial Cancer Patients at Rajavithi Hospital

  • Prueksaritanond, Nisa;Cheanpracha, Patchara;Yanaranop, Marut
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.3
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    • pp.1489-1492
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    • 2016
  • Background: Although there are no biomarkers that are routinely used in endometrial cancer (EC) management, many studies have found that serum human epididymis protein 4 (HE4) is superior to cancer antigen 125 (CA125) in the detection of EC. The correlation of HE4 with two prognostic factors for EC, primary tumor diameter (PTD) and depth of myometrial invasion (DMI) may be useful in identifying EC patients at high risk of lymphatic dissemination. Objective: To evaluate the correlation of serum HE4 with PTD and DMI in patients with EC. Materials and Methods: A cross-sectional study was conducted on 70 EC patients who were scheduled for elective surgery at Rajavithi Hospital between 1st September 2013 and 30th May 2014. Preoperative serum levels of HE4 and CA125 were investigated, and then gross measurement of PTD was taken and postoperative pathologic slides were reviewed for DMI including histologic types, grading and staging. Results: Preoperative serum HE4 levels were strongly correlated with PTD (r=0.65, p<0.001) and moderately correlated with DMI (r=0.46, p<0.001). Moreover, serum HE4 levels were significantly elevated in EC patients with PTD >2 cm (p<0.001) and DMI > 50% (p=0.004). The performance of serum HE4 in identifying EC patients at low risk and high risk of lymph node metastasis was significantly better than that of CA125 (AUC 0.88 vs. 0.65, p=0.003). At an optimal cut-off value of 70 pM/L, serum HE4 had a sensitivity of 83.3% and a specificity of 80.0%. Conclusions: In EC patients, preoperative serum HE4 is significantly correlated with PTD and DMI. Serum HE4 levels could be useful in identifying endometrial cancer patients at high risk of lymphatic spread who would benefit from systemic lymphadenectomy at the cut-off value of 70 pM/L.

Basic Performance Evaluation of the Ecotoxicity Detection Device for Heavy Metals (중금속류 생태독성 검출장치의 기초성능 평가)

  • Kim, IlHo;Kim, Ji-Sung;Yoon, Young-Han;Ban, Hyo-Jin;Kim, Seok-Gu
    • Journal of Korean Society of Environmental Engineers
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    • v.34 no.12
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    • pp.828-834
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    • 2012
  • The ecotoxicity detection device for preliminary test (Test jig) was manufactured to develop the biological early warning system using Vibrio fischeri. In this study, the ecotoxicity detection charateristics of the Test jig was investigated for 6 heavy metals (Cr, Zn, Pb, Cd, Cu and Hg). It was observed that relative luminescence unit (RLU) of Vibrio fischeri constantly decreased by the concentrations of the tested heavy metals. In contrast with other heavy metals, RLUs of Pb and Hg constantly decreased even at low concentrations. RLU of Hg drastically decreased when its concentration increased from 0.13 mg/L to 0.25 mg/L. $EC_{50}$ values of Cr, Zn, Pb and Cd gradually decreased with exposure time, whereas there was no significant change in $EC_{50}$ values of Cu and Hg with time. On the other hand, $EC_{50}$ values between the Test jig and Reference device were compared to evaluate the ecotoxicity detection performance of the Test jig. No big difference was found in $EC_{50}$ vlaues between the two devices, indicating that the Test jig could be applied as the ecotoxicity detection device for heavy metals.

Refunds Reusable Electronic Check Payment System Using an EC-KCDSA Partially Blind Signature (EC-KCDSA 부분 은닉서명을 이용한 거스름 재사용 가능한 전자수표지불 시스템)

  • 이상곤;윤태은
    • Journal of the Korea Institute of Information Security & Cryptology
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    • v.13 no.1
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    • pp.3-10
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    • 2003
  • In this paper, a partially blind signature schemes baled on EC-KCDSA is proposed and we applied it to design an electronic check payment system. Because the proposed partially blind signature scheme uses elliptic curve cryptosystem, it has better performance than any existing schems using RSA cryptosystem. When issuing a refund check, one-time pad secret key is used between the bank and the customer to set up secure channel. So the symmetric key management is not required.

Effects of future climate conditions on photosynthesis and biochemical component of Ulva pertusa (Chlorophyta)

  • Kang, Eun Ju;Kim, Kwang Young
    • ALGAE
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    • v.31 no.1
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    • pp.49-59
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    • 2016
  • Ulva pertusa, a common bloom-forming green alga, was used as a model system to examine the effects of elevated carbon dioxide (CO2) and temperature on growth and photosynthetic performance. To do this, U. pertusa was grown under four temperature and CO2 conditions; ambient CO2 (400 μatm) and temperature (16℃) (i.e., present), elevated temperature only (19℃) (ET; i.e., warming), elevated CO2 only (1,000 μatm) (EC; i.e., acidification), and elevated temperature and CO2 (ET and EC; i.e., greenhouse), and its steady state photosynthetic performance evaluated. Maximum gross photosynthetic rates (GPmax) were highest under EC conditions and lowest under ET conditions. Further, ET conditions resulted in decreased rate of dark respiration (Rd), but growth of U. pertusa was higher under ET conditions than under ambient temperature conditions. In order to evaluate external carbonic anhydrase (eCA) activity, photosynthesis was measured at 70 μmol photons m−2 s−1 in the presence or absence of the eCA inhibitor acetazolamide (AZ), which inhibited photosynthetic rates in all treatments, indicating eCA activity. However, while AZ reduced U. pertusa photosynthesis in all treatments, this reduction was lower under ambient CO2 conditions (both present and warming) compared to EC conditions (both acidification and greenhouse). Moreover, Chlorophyll a and glucose contents in U. pertusa tissues declined under ET conditions (both warming and greenhouse) in conjunction with reduced GPmax and Rd. Overall, our results indicate that the interaction of EC and ET would offset each other’s impacts on photosynthesis and biochemical composition as related to carbon balance of U. pertusa.

Preparation of Polymer-Metal Complexed Membranes using Ethylcellulose and Metal salts, and Their Characteristics of Gas Separation. (Ethylcellulose와 금속염을 이용한 고분자-금속 착체막의 제조 및 기체투과특성)

  • 변홍식;서성호;박병규;홍병표;백승욱;박영규
    • Membrane Journal
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    • v.13 no.3
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    • pp.200-209
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    • 2003
  • Polymer-metal complexed membranes were prepared by solvent evaporation method using ethylcellulose, platinum(II)acetylacetonate, and rhodium(III)acetylacetonate. The various composition of metal salt(0.3-4.0 wt%) were employed to obtain the optimum performance of final membrane. EC-metal complexed membranes were characterized by FTIR and scanning electron microscopy(SEM) to observe the morphology and the performance of oxygen, nitrogen, carbon dioxide, and methane gases was tested. It was shown that the metal salts enhanced the permeability of all gases without decrease of selectivity. However, it was found that Pt had more effects on the permeability of oxygen and nitrogen gases while Rh had more effects on the permeability of carbon dioxide and methane gases. EC-Pt complexed membrane(Pt 1.0 wt%) even showed the enhanced selectivity of oxygen/nitrogen(37%) due to the affinity characteristic of Pt to oxygen.

A Design of Real-Time QRS Detection in Physio-Module for Echocardiography (심초음파용 실시간 심전도 QRS 검출 모듈에 관한 연구)

  • Jang, Won-Seuk;Kim, Nam-Hyun;Kim, Eong-Sok;Jeon, Dae-Keun
    • Journal of the Institute of Electronics Engineers of Korea SC
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    • v.47 no.3
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    • pp.40-47
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    • 2010
  • In this study, we investigated the performance of real-time QRS complex detection algorithm in physio-module for echocardiography. The performance of QRS detection module in echocardiography was evaluated according to international standard, EC-13 and we compared with commercialized physio-module with QRS complex detection. In this study, we can get performance of QRS complex detection, pacer pulse detection, Tall t-wave rejection and arrhythmia detection within EC-13's criteria and we can get improved QRS trigger delay time and baseline wondering rejection times in compared with commercialized physio-module.

Performance Analysis of Error Classification running on Digital Carousel System of Home Network (홈 네트워크의 디지털 캐로절 시스템에서 오류분류 성능 분석)

  • Ko, Eung-Nam
    • Journal of Digital Contents Society
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    • v.8 no.4
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    • pp.587-592
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    • 2007
  • This paper explains the design and implementation of the EC_NH. EC_NH is a system that is suitable for detecting, sharing and recovering software error based on multimedia CSCW(Computer Supportes Cooperated Work). With error sharing system, a group cooperating users can share error applications. From the perspective of multimedia collaborative environment, an error application becomes another interactive presentation error is shared with participants engaged in a cooperative work. Our Digital Carousel enables user to share media objects through media synchronization mechanism. We implemented the Digital Carousel so that the users participated in collaborative work may refer shared media or error objects as the same view to others.

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Coordination Approach for Electronic Commerce Development (전자상거래 개발을 위한 코디네이션 접근 방식)

  • Kim, Hee-Woong;Malone, Thomas W.
    • Asia pacific journal of information systems
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    • v.10 no.4
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    • pp.133-152
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    • 2000
  • Successful Electronic Commerce(EC) requires not only a transformation of the supply chain but a redesign of organizational processes as well. Just as the organizations in a supply chain must cooperate with each other to achieve a collective goal, so too do the departments and groups that comprise an organization depend on each other to achieve the organization's goals. A lack of coordination at either of these levels can result in poor performance and high coordination costs. In addition, changes in inter-organizational dependencies can affect the dependencies within the affected organizations. The lack of coordination across two levels results in a transition gap in transforming the inter-organizational design to the intro-organizational design in EC deployments. The purpose of this research is to develop a modeling method for coordination, managing the linkage between inter- and intra-organizations in EC deployments. The method was applied to the EC development project of a cable TV home-shopping company. The coordination approach enabled us to manage dependencies among the coordination elements and identify the effect of a change on other elements, which became the basis for effective EC deployments. We will discuss the method and compare it with other dependency management methods.

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Experimental study on the effect of EC-TMD on the vibration control of plant structure of PSPPs

  • Zhong, Tengfei;Feng, Xin;Zhang, Yu;Zhou, Jing
    • Smart Structures and Systems
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    • v.29 no.3
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    • pp.457-473
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    • 2022
  • A high-frequency vibration control method is proposed in this paper for Pumped Storage Power Plants (PSPPs) using Eddy Current Tuned Mass Damper (EC-TMD), based on which a new type of EC-TMD device is designed. The eddy current damper parameters are optimized by numerical simulation. On this basis, physical simulation model tests are conducted to compare and study the effect of structural performance with and without damping, different control strategies, and different arrangement positions of TMD. The test results show that EC-TMD can effectively reduce the control effect under high-frequency vibration of the plant structure, and after the additional damping device forms EC-TMD, the energy dissipation is further realized due to the intervention of eddy current damping, and the control effect is subsequently improved. The Multi-Tuned Mass Damper (MTMD) control strategy broadens the tuning band to improve the robustness of the system, and the vibration advantage is more obvious. Also, some suggestions are made for the placement of the dampers to promote their application.

Effect of Dietary α-1,6-Galactosidase and β-1,4-Mannanase on Growth Performance and Nutrient Digestibility in Nursery and Growing Pigs (자돈 및 육성돈에 있어 α-1,6-galactosidase와 β-1,4-mannanase의 사료내 첨가가 성장 및 영양소 소화율에 미치는 영향)

  • Kwon, O. S.;Kim, I. H.;Lee, S. H.;Hong, J. W.;Kim, J. H.;Moon, T. H.;Lee, J. H.
    • Journal of Animal Science and Technology
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    • v.45 no.2
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    • pp.211-218
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    • 2003
  • For the Exp. 1, a total of sixty pigs (10.57$\pm$0.30kg average initial body weight) were used in a 15-d growth assay to determine the effect of dietary $\alpha$-1,6-galactosidase and $\beta$-1,4-mannanase on growth performance and nutrient digestibility. Dietary treatments included 1) CON (corn-dried whey-SBM based diet), 2) EC0.1 (CON diet+0.1% enzyme complex of $\alpha$-1,6-galactosidase and $\beta$-1,4-mannanase). Through the entire experimental period, gain/feed of pigs fed EC0.1 diet was higher (0.43 vs 0.52) than that of pigs fed CON diet (P<0.05). Pigs fed EC0.1 diet showed significant (P<0.05) improvement in dry matter (74.82% vs 82.41%) and nitrogen (70.59% vs 77.88%) digestibilities compared to pigs fed CON diet. For the Exp. 2, a total of thirty six pigs (22.30$\pm$0.45kg average initial body weight) were used in a 30-d growth assay to determine the effects of dietary $\alpha$-1,6-galactosidase and $\beta$-1,4-mannanase in low energy diet on growth performance and nutrient digestibility. Dietary treatments included 1) AME (adequate ME diet), 2) AME+EC0.1 (AME diet+0.1% enzyme complex) and LME+EC0.1 (low ME diet + 0.1% enzyme complex). Through the entire experimental period, average daily feed intake of pigs fed enzyme complex supplemented diets was higher than that of pigs fed CON diet (P<0.05). Also, pigs fed AME+EC0.1 diet showed significant (P<0.05) increase in ADFI (1,401g vs 1,733g) compared to pigs fed CON diet. Pigs fed enzyme complex supplemented diet showed significant (P<0.05) improvement in dry matter and nitrogen digestibilities compared to pigs fed CON diet. In conclusion, the results obtained from these feeding trials suggest that the supplementation of $\alpha$-1,6-galactosidase and $\beta$-1,4-mannanase was an effective means for improving growth performance and dry matter and nitrogen digestibilities in nursery and growing pigs.