• Title/Summary/Keyword: E2F

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Effect of F$e_2$P Addition on Microstructures of Sintered 4600 Steel (4600계 소결강의 조직에 미치는 F$e_2$P첨가의 영향)

  • Kim, Dong-Uk;Lee, Wan-Jae
    • Korean Journal of Materials Research
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    • v.2 no.6
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    • pp.428-435
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    • 1992
  • AISI 4600 Iron powder was mixed with 0~1.0% phosphor as F$e_2$P powder and/or 0~0.8% carbon as graphite powder in rotating mixer. Mixed powder was pressed 800MPa in double-punch mould. Compacts were sintered at 115$0^{\circ}C$for 30 min. in vacuum or mixed hydrogen and nitrogen gas. Sintered compacts were ground and polished, and etched by 2% nital etchant. The microstructure was observed by image analyzer and optical microscope. Density and microhardness were tested by ASTM B3l2 and Microvickers hardness tester. The results obtained were as follows : (1) As the amount of F$e_2$P powder increased, sintered microstructure showed more densified effect and the grain size was larger. (2) The shape of pore was rounded and the number of pore was decreased by F$e_2$P addition. But mean pore size was larger with F$e_2$P content. (3) Simultaneous alloying addition of F$e_2$P and graphite brought about larger grain growth than respective addition. (4) Sintering atmosphere did not affect the microstructure. (5) Hardness of sintered compact increased with phosphrous and carbon content.

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The Ubiquitin-Proteasome System and F-box Proteins in Pathogenic Fungi

  • Liu, Tong-Bao;Xue, Chaoyang
    • Mycobiology
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    • v.39 no.4
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    • pp.243-248
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    • 2011
  • The ubiquitin-proteasome system is one of the major protein turnover mechanisms that plays important roles in the regulation of a variety of cellular functions. It is composed of E1 (ubiquitin-activating enzyme), E2 (ubiquitin-conjugating enzyme), and E3 ubiquitin ligases that transfer ubiquitin to the substrates that are subjected to degradation in the 26S proteasome. The Skp1, Cullin, F-box protein (SCF) E3 ligases are the largest E3 gene family, in which the F-box protein is the key component to determine substrate specificity. Although the SCF E3 ligase and its F-box proteins have been extensively studied in the model yeast Saccharomyces cerevisiae, only limited studies have been reported on the role of F-box proteins in other fungi. Recently, a number of studies revealed that F-box proteins are required for fungal pathogenicity. In this communication, we review the current understanding of F-box proteins in pathogenic fungi.

THREE RESULTS ON TRANSCENDENTAL MEROMORPHIC SOLUTIONS OF CERTAIN NONLINEAR DIFFERENTIAL EQUATIONS

  • Li, Nan;Yang, Lianzhong
    • Bulletin of the Korean Mathematical Society
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    • v.58 no.4
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    • pp.795-814
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    • 2021
  • In this paper, we study the transcendental meromorphic solutions for the nonlinear differential equations: fn + P(f) = R(z)eα(z) and fn + P*(f) = p1(z)eα1(z) + p2(z)eα2(z) in the complex plane, where P(f) and P*(f) are differential polynomials in f of degree n - 1 with coefficients being small functions and rational functions respectively, R is a non-vanishing small function of f, α is a nonconstant entire function, p1, p2 are non-vanishing rational functions, and α1, α2 are nonconstant polynomials. Particularly, we consider the solutions of the second equation when p1, p2 are nonzero constants, and deg α1 = deg α2 = 1. Our results are improvements and complements of Liao ([9]), and Rong-Xu ([11]), etc., which partially answer a question proposed by Li ([7]).

A Study OH Mossbauer Spectra Of the $Li_{0.5}Fe_{2.5-x}Al_xO_4$ Ferrite System (Li_{0.5}Fe_{2.5-x}Al_xO_4 페라이트계의 Mossbauer 스펙트럼 연구)

  • 백승도
    • Journal of the Korean Magnetics Society
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    • v.11 no.2
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    • pp.58-62
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    • 2001
  • The L $i_{0.5}$F $e_{2.5-x}$A $l_{x}$ $O_4$ systems (x=0, 0.3, 0.6, 0.9, 1.2, 1.5) were investigated by X-ray diffraction and Mossbauer spectroscopy. The structure of all the samples is cubic spinel type and lattice constant decrease with increasing Al content x. The Moissbauer spectra reveal two sextet for 0$\leq$x$\leq$0.6, two sextet and a doublet for 0.9$\leq$x$\leq$1.2, and a doublet for x=1.5. The cation distribution of the samples is (L $i_{1-a}$$^{+}$F $e_{a}$ $^{3+}$)$^{A}$[L $i_{a-0.5}$$^{+}$A $l_{2.5-a-x}$$^{+}$F $e_{2.5-a-x}$$^{3+}$]$^{B}$ $O_4$$^{2-}$ and substituted $Al^{3+}$ ions decrease the covalency of F $e^{3+}$- $O^{2-}$ bond in B-sites and A-B super-exchange interactions.tions.s.tions.ons.s.

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On the Order of Growth of Solutions to Complex Non-homogeneous Linear Differential Equations

  • Habib, Habib;Belaidi, Benharrat
    • Kyungpook Mathematical Journal
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    • v.56 no.3
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    • pp.819-829
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    • 2016
  • In this paper, we study the order of growth of solutions to the non-homogeneous linear differential equation $$f^{(k)}+A_{k-1}e^{az}f^{(k-1)}+{\cdots}+A_1e^{az}f^{\prime}+A_0e^{az}f=F_1e^{az}+F_2e^{bz}$$, where $A_j(z)$ (${\not\equiv}0$) ($j=0,1,{\cdots},k-1$), $F_j(z)$ (${\not\equiv}0$) (j = 1, 2) are entire functions and a, b are complex numbers such that $ab(a-b){\neq}0$.

Effect of E-box and E2F Binding Site on Transcriptional Activity in MCM Promoter (MCM promoter에서 E-box와 E2F 결합부위가 전사활성에 미치는 영향)

  • 권현주
    • Journal of Life Science
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    • v.14 no.5
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    • pp.732-740
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    • 2004
  • MCM proteins are essential for eukaryotic DNA replication, playing roles in the initiation and elongation of DNA replication. MCM proteins expression is much higher in malignant tissues than normal tissues. Several reports have indicated the usefulness of MCM proteins as markers of cancer cells in histopathological diagnosis. However, the cause of enhanced expression of MCM proteins in cancer cells remain to be clarified. The purpose of this study is to examine the relative transcriptional activities of human mcm gene promoters in cancer and normal cells. The minimal promoter region required for transcription of a luciferase reporter gene was contained an E-box and one E2F site. In addition, luciferase activities from mcm7 and mcm2 promoter/luciferase gene reporter constructs were significantly increased in cancer cells at 8 times compared with normal cells. E-box and E2F binding site in the promoter of mcm genes are responsible for different mechanism of transcription regulation on the cellular environment.

EXISTENCE OF TRANSCENDENTAL MEROMORPHIC SOLUTIONS ON SOME TYPES OF NONLINEAR DIFFERENTIAL EQUATIONS

  • Hu, Peichu;Liu, Manli
    • Bulletin of the Korean Mathematical Society
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    • v.57 no.4
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    • pp.991-1002
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    • 2020
  • We show that when n > m, the following delay differential equation fn(z)f'(z) + p(z)(f(z + c) - f(z))m = r(z)eq(z) of rational coefficients p, r doesn't admit any transcendental entire solutions f(z) of finite order. Furthermore, we study the conditions of α1, α2 that ensure existence of transcendental meromorphic solutions of the equation fn(z) + fn-2(z)f'(z) + Pd(z, f) = p1(z)eα1(z) + p2(z)eα2(z). These results have improved some known theorems obtained most recently by other authors.

Evaluation of the virulence genes and Shiga toxin-producing abilities of Escherichia coli field isolates causing edema disease in pigs (국내 분리 돼지 부종병 대장균의 병원성 유전자 및 시가독소 생성 검증)

  • Seo, Byoung-Joo;Jeong, Chang-Gi;Kang, A-Rum;Cho, Ho-Seong;Kim, Won-Il
    • Korean Journal of Veterinary Service
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    • v.39 no.2
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    • pp.87-92
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    • 2016
  • Porcine edema disease (ED) is a communicable disease of pigs caused by infection with Shiga toxin (Stx)-producing Escherichia coli (STEC) which expresses F18 fimbriae and/or Stx type 2e (Stx2e). While STEC causes a severe illness including hemorrhagic colitis and hemolytic-uremic syndrome in humans, it induces damage to the vascular endothelium, which results in edema, hemorrhage, and microthrombosis, leading in high mortality in pigs. In the present study, we cultured Stx2e-producing E. coli field isolates from conventional pig farms that experienced sudden deaths previously with symptoms similar to porcine edema disease, which were further investigated with Shiga toxin profiles. A total of 43 strains were identified from the collected samples by F18 or Stx2e specific PCR. Based on the PCR, 42 isolates out of 43 isolates were proved to carry one of F18 or Stx2e genes and 14 isolates to carry both F18 and Stx2e genes. All of the 30 isolates that harbored Stx2e gene induced the cytopathic effect (CPE) in vero cells and especially, the isolate 150229 produced the highest level of Shiga toxin. Therefore, we identified the virulence genes (F18 and Stx2e) and demonstrated Shiga toxin-producing abilities from porcine edema disease causing E. coli filed isolates. These results suggested that one of the isolates could be a vaccine antigen candidate against STEC through further investigating to elicit an immune response.

$SiO_2$ Etching in $C_4F_{8}$ Plasma by E-ICP ($C_4F_{8}O_2$ 공정기체와 E-ICP를 이용한 산화막 식각)

  • 송호영;조수범;이종근;오범환;박세근
    • Proceedings of the IEEK Conference
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    • 2001.06b
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    • pp.197-200
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    • 2001
  • Novel Enhanced Inductively Coupled Plasma is applied to etch $SiO_2$. Effect of $O_2$ or Ar addition to $C_{4}F_{8}$ gas is monitored by Optical Emission Spectroscopy and Quadrupole Mass Spectrometer. It is fund that Ar or $O_2$ dilution to $C_{4}F_{8}$ increases F emission intensity and decreases $CF_2$ intensity. However, the ac frequency to the Helmholtz coil decreases the F intensity and thus increases $CF_2$/F ratio. By adjusting the ac frequency, the optimum etch rate and PR to $SiO_2$ selectivity can be obtained in E-lCP.

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Theoretical study on the structures and the electron affinities of cyclic perfluoroalkanes (c-PFA) (Cyclic perfluoroalkanes(c-PFA)의 분자구조 및 분광학적 성질에 관한 이론 연구)

  • Jeong, Sung-Yup;Shin, Chang-Ho;Kim, Seung-Joon
    • Analytical Science and Technology
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    • v.26 no.1
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    • pp.51-60
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    • 2013
  • The geometrical parameters, vibrational frequencies, and adiabatic electron affinities (AEAs) for c-$C_nF_{2n}$ (n=8, 9) and $C_{10}F_{18}$ (perfluorodecalin) have been investigated using various quantum mechanical techniques. The possible structures for the neutrals and anions of c-PFA are fully optimized and electron affinities are predicted using energy difference between the neutral and anion. The harmonic vibrational frequencies are also determined and zero-point vibrational energies (ZPVEs) are considered for the better prediction of the electron affinities. The electron affinities are predicted to be 1.18 eV for c-$C_8F_{16}$ (ortho), 1.37 eV for c-$C_9F_{18}$, and 1.38 eV for $C_{10}F_{18}$ (perfluorodecalin) at the MP2 level of theory after ZPVE correction.