• Journal of the Korean Society of Radiology
• /
• v.12 no.4
• /
• pp.475-480
• /
• 2018

In lower abdominal MRI scan, patients have been tested by physically contacting with the body array coil. In this study, we have designed the acrylic assistant equipment (ACR) which allows the contactless scan of the patient to the coil and evaluated the feasibility by comparing the acquired images with ACR to those obtained without ACR. We tested 10 cases (F: 5, m: 5) by using the Ingenia $3.0T^{TM}$ MR system and dStreamTM torso coil (Philips Healthcare, Netherlands). We implemented T1 AX TSE and eTHRIVE (GRE) techniques. The scanned images were quantitatively and qualitatively assessed. In qualitatively, the TSE shows 4.44 and 4.56 mean values with and without the ACR and 4.34 and 4.28 at the GRE, respectively. In quantitatively, the TSE shows 12.15 CNR, 17.95 SNR and 12.71 CNR, 18.96 SNR with and without the ACR. And GRE shows 17.72 CNR, 22.59 SNR and 18.26 CNR, 24.47 SNR with and without the ACR, respectively. We have designed and implemented the acrylic assistant equipment to lower abdominal patients. Our data indicate that it is possible to obtain similar image qualities to current lower abdominal MRI scan without the physical contact to the patient.

• Journal of Society of Preventive Korean Medicine
• /
• v.4 no.1
• /
• pp.32-50
• /
• 2000

On the process of research in the plan on oriental medical participation in the industrial health sponsored by BK21 project, we carried out the oriental medical health examination program for workers during former half-year We reached the conclusion as follows, 1. The oriental medical health examination program is contents and formalities that should be determined by present industrial health system, based on the oriental medical system and scholastic character, and included probability of the western and oriental medical cooperation. 2. The oriental medical health examination program can promote capability of individual health management and productive power of workers, and it is capable to manage on the self-conscious symptoms and macroschophically approach to their environment 3. The oriental medical health examination program that we have developed, is flow as questionare, understanding of working environment, information of result and later management. It is composed of three fields as follow , first, use of pulse diagnostic apparatus, understanding of the health promotion life style, and diagnosis of the oriental medical doctor, second, analysis of constitution, third, photographing for understanding of the musculoskeletal disorders, questionare for musculoskeletal self-conscious symptoms, and diagnosis of oriental medical doctor. 4. The oriental medical health examination program that we have developed, progressive from the view point of health, makes the oriental medical doctor's roll more important. It is the first trial at the western and oriental medical cooperation and characterized by excellence about musouloskeletal disorders. But it need to be improved in aspects of time and specialist on the health examination, diagnostic apparatus, control of examinant and later management. So we think that it needs research on the employment of health examination specialist, establishment of later management system, development of significantly diagnosable standard and assessable form on the health examination, and contents of health examination on the western and oriental medical cooperation.

• The Korean Journal of Physiology and Pharmacology
• /
• v.18 no.5
• /
• pp.411-418
• /
• 2014

Vascular remodelling is an adaptive mechanism, which counteracts pressure changes in blood circulation. Nicotine content in cigarette increases the risk of hypertension. The exact relationship between nicotine and vascular remodelling still remain unknown. Current study was aimed to determine the effect of clinically relevant dosage of nicotine (equivalent to light smoker) on aortic reactivity, oxidative stress markers and histomorphological changes. Twelve age-matched male Sprague-Dawley rats were randomly divided into two groups, i.e.: normal saline as control or 0.6 mg/kg nicotine for 28 days (i.p., n=6 per group). On day-29, the rats were sacrificed and the thoracic aorta was dissected immediately for further studies. Mean arterial pressure (MAP) and pulse pressure (PP) of nicotine-treated vs. control were significantly increased (p<0.05). Nicotine-treated group showed significant (p<0.05) increase tunica media thickness, and decrease in lumen diameter, suggesting vascular remodelling which lead to prior hypertension state. The phenylephrine (PE)-induced contractile response in nicotine group was significantly higher than control group ($ED_{50}=1.44{\times}10^5M$ vs. $4.9{\times}10^6M$) (p<0.05~0.001). However, nicotine-treated rat showed significantly lower endothelium-dependent relaxation response to acetylcholine (ACh) than in control group ($ED_{50}=6.17{\times}10^7M$ vs. $2.82{\times}10^7M$) (p<0.05), indicating loss of primary vascular function. Malondialdehyde (MDA), a lipid peroxidation marker was significantly higher in nicotine group. Superoxide dismutase (SOD) enzymatic activity and glutathione (GSH) were all reduced in nicotine group (p<0.05) vs. control, suggesting nicotine induces oxidative imbalance. In short, chronic nicotine administration impaired aortic reactivity, probably via redox imbalance and vascular remodelling mechanism.

• Proceedings of the Korean Society of Developmental Biology Conference
• /
• 2003.10a
• /
• pp.121-121
• /
• 2003

The standard protocol for the production of transgenic mouse from ES-injected embryo has to process via chimera producing and several times breeding steps, In contrast, tetraploid-ES cell complementation method allows the immediate generation of targeted murine mutants from genetically modified ES cell clones. The advantage of this advanced technique is a simple and efficient without chimeric intermediates. Recently, this method has been significantly improved through the discovery that ES cells derived from hybrid strains support the development of viable ES mice more efficiently than inbred ES cells do. Therefore, the objective of this study was to generate transgenic mice overexpressing human resistin gene by using tetrapioid-ES cell complementation method. Human resistin gene was amplified from human fetal liver cDNA library by PCR and cloned into pCR 2.1 TOPO T-vector and constructed in pCMV-Tag4C vector. Human resistin mammalian expression plasmid was transfected into D3-GL ES cells by lipofectamine 2000, and then after 8~10 days of transfection, the human resistin-expressing cells were selected with G418. In order to produce tetraploid embryos, blastomeres of diploid embryos at the two-cell stage were fused with two times of electric pulse using 60 V 30 $\mu$sec. (fusion rate : 93.5%) and cultured upto the blastocyst stage (development rate : 94.6%). The 15~20 previously G418-selected ES cells were injected into tetraploid blastocysts, and then transferred into the uterus of E2.5d pseudopregnant recipient mice. To investigate the gestation progress, two El9.5d fetus were recovered by Casarean section and one fetus was confirmed to contain human resistin gene by genomic DNA-PCR. Therefore, this finding demonstrates that tetraploid-ES mouse technology can be considered as a useful tool to produce transgenic mouse for the rapid analysis of gene function in vivo.

• Journal of the Korean Society of Clothing and Textiles
• /
• v.11 no.3 s.25
• /
• pp.41-55
• /
• 1987

The purpose of this study is to investigate the effects of napping of knitted fabric on wear sensation and physiological responses. Experimental garments were four types of warm-ups made of either $100\%$ PET or $65/35\%$ P /C and either napped or unnapped respectively. Two healthy young female adults were chosen as subjects for the experiment. Experimental room conditions were as follows: Temp., $22\pm0.5^{\circ}C$ R.H., $54\pm3\%$ and Air Velocity, 0.25m/ sec or 2. 86m/sec. The subjects exercised on bicycle ergometer and rested alternatively for totally 45-min. The results are summarized as follows. 1) With napped Warm-up, chest, back, mean skin temp. and microclimates, i.e., temp., relative humidity and water vapor pressure inside the clothing, were higher than with unnapped warm-up. And there was no difference in pulse rate between napped and unnapped warm-ups. 2) Wear sensations of thermal, humidity, tactile and comfort were 'more hot' and 'more uncomfortable' in 0.25m/sec air velocity. but in 2.86m/sec condition the tactile sensation was 'better' and 'more comfortable' with napped warm-ups. According to Pearson's Correlation, among various kinds of wear sensations, tactile is most related with comfort. From these results, it can be concluded that napped fabric decreases the rate of heat trans? mission and moisture diffusion through the clothing. Therefore skin and body temp. and temp., R.H., Vapor Pressure inside the clothing are increased.

• Journal of the Korean Society of Costume
• /
• v.36
• /
• pp.25-41
• /
• 1998

The purpose of this research was to study four impulse buying dimensions and planned buying, marketing stimulus factors in store, buying im-pulse and impulse buying of female consumer. The female consumers were divided into three groups, i.e., college students, housewives and workingwomen. 408 women living in Kyung Nam were selected as respondents by convenience sampling methods. The results of this research can be summarized as follows. 1. The overall impulses were stronger for college students and workingwomen than house-wives. The impulse buying dimensions were different according to the status of women. 2. Buying impulse and impulse buying of clothing were more likely to be for college students and working women than housewives. 3. The display in the store gave the information to the three groups equally. These infor-mations helped to make the impulse buying. 4. The marketing stimulus factors were different according to the status of respondents. Sensitive and aesthetic factors were important for college students and workingwomen, and the utility of clothing were important for house-wives. The color of clothing, the discount of regular price and the low price had the same meanings to the three groups. 5. Impulse buying dimensions were effected by the marketing stimulus factors. 6. The fashionable products, the use of credit card, famous brand, gracious display of clothing and the kind services of salesman were the common factors that stimulate the consumer to buy the clothings. But the color and design of products had more effect on the college students, and the discount of regular price and the utility of clothing were more important for the workingwomen. The color and the utility of clothing were stimulus factors for the housewives.

• 한국전산유체공학회:학술대회논문집
• /
• 2008.03b
• /
• pp.54-60
• /
• 2008

The atomization characteristics of the dual air supplying twin-fluid nozzle were investigated experimentally using PIV and PDA systems. The two-fluid nozzle is composed of three main parts: the feeding injector to supply fluid that is controlled by a PWM (pulse-width modulation) mode, the adaptor as a device with the ports for supplying the carrier and assist air and the main nozzle to produce the spray. The main nozzle has the swirl tip with four equally spaced tangential slots, which give the injecting fluid an angular momentum. The angle of the swirl tip varied with 0$^{\circ}$ 30$^{\circ}$, 60$^{\circ}$ and 90$^{\circ}$, and the ratios of carrier air to assist air and ALR(total air to liquid) were 0.55 and 1.23, respectively. The macroscopic behavior of the spray was investigated using PIV system, and the mean velocity, turbulent intensity and SMD distributions of the sprays were measured using PDA system. As the results, the mean axial velocity at the spray centerline decrease with the increase of the swirl angle. The turbulent intensities of the axial and radial velocity were increased with the increase of the swirl angle. The mean SMD (Sauter mean diameter) of the radial direction along the axial distance shows the lowest value at the swirl angle of 60$^{\circ}$.

• Journal of Acupuncture Research
• /
• v.27 no.2
• /
• pp.23-30
• /
• 2010

Objectives : The second derivative of photoplethysmogram waveform(SDPTG) is a simple, convenient and non-invasive technique for pulse wave analysis. This study was designed to investigate the differences in the SDPTG between the affected side and the unaffected side in hemiparetic patients after stroke, and the effects of acupuncture at Palsa(BaXie) in hemiparetic patients after stroke. Methods : To evaluate the differences between the affected side and the unaffected side in hemiparetic patients after stroke, their SDPTG were recorded by using a Cardio Peri SA6000. To evaluate the effects of acupuncture at Palsa(BaXie) in 20 hemiparetic patients after stroke and 20 healthy subjects, their SDPTG were recorded 2 times(pre-acupuncture and post-acupuncture). The SDPTG consists of an a, b, c and d wave in systole and an e wave in diastole. Sano aging index was defined as (b-c-d)/a. Results : 1. The affected side in hemiparetic patients after stroke had higher average b/a ratio(p<0.05)and Sano aging index(p<0.05) than the unaffected side 2. In a comparison of pre-acupuncture and post-acupuncture at the Palsa(BaXie), b/a ratio(p<0.05) and Sano aging index(p<0.05) was decreased significantly in both hemiparetic patients and healthy subjects. Conclusions : These findings suggest that acupuncture at Palsa(BaXie) may be effective method of reverting some of the deleterious effects on vascular function produced by stroke.

• Journal of Biomedical Engineering Research
• /
• v.23 no.6
• /
• pp.437-449
• /
• 2002

Coronary arteries are subjected to very different flow conditions compared to other arteries in systemic blood circulation. We Performed a computational fluid dynamic research to investigate influence of such flow conditions in coronary arteries on development and progress of atherosclerosis in the same. The results showed big differences in the flow field of the coronary artery compared to the abdominal and femoral arteries. The coronary artery showed higher wall shear stresses due to the small vessel diameter. On the other hand, it showed only one vortex distal to the stenosis throat during a whole pulse cycle. However. several vortices were observed in the abdominal and femoral arteries in both proximal and distal sides of the stenosis throat The wall shear stresses and extent of recirculation area were increased with impedance phase angle increasing toward more negative values. Therefore, cardiac contraction and the negative impedance phase angle as large as -110。 may induce a flow field that accelerates atherosclerosis.

• Science of Emotion and Sensibility
• /
• v.1 no.2
• /
• pp.13-22
• /
• 1998

The sense of touch has both objective and subjective characteristics. During hand evaluation of the fabrics. psycho physiological processes such as emotion and stimulation. On other site, the mode of touch (passive vs. active) is also capable to modulate somatosensory responses. I.e., suppress somatocensory perception during active electrocortical responses to passive and active touch of the textiles with different subjective emotional preference. The study was carried out on 36 female college students. Physiological signals were acquired by Grass and BIOPAC 100 systems with AcqKnowledge variables, namely heart rate (HR), respiratory sinus arrhythmia (RSA), pulse transit time (PTT), respiration rate (RSP) and skin conductance parameters (SCL, amplitude, risetime and number of SCRs) were analyzed for baseline and stimulation conditions. Analysis was manifested in a form of moderate HR acceleration. RSP increase, RSA decrease (lowered vagal tone), decreased PTT and increased electrodermal activity (increased SCL, several SCRs) that reflects general sympathetic activation. Parietal EEG effects (on contra-lateral side to stimulated hand)were featured by short-term alpha-blocking, slightly reduced theta, significantly increased delta and enhanced fast beta activity with few variations across stimuli. The main finding of the study was that most and least preferred textures exhibited significant differences in autonomic (HR, RSP, PTT, SCR, and at less extent in RSA and SCL) and electrocortical responses (delta, slow and fast alpha, fast beta relative power). These differences were recorded both in passive and active stimulation modes, thus demonstrating reproducibility of distinction between most and least emotionally preferred tactile stimuli, suggesting influence of psychological factors, such as emotional property of stimulus, on physiological outcome.