• Journal of Microbiology and Biotechnology
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• 제24권2호
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• pp.287-294
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• 2014

The transcription factor E2F1 is active during G1 to S transition and is involved in the cell cycle and progression. A recent study reported that increased E2F1 is associated with DNA damage and tumor development in several tissues using transgenic models. Here, we show that E2F1 expression is regulated by tristetraprolin (TTP) in prostate cancer. Overexpression of TTP decreased the stability of E2F1 mRNA and the expression level of E2F1. In contrast, inhibition of TTP using siRNA increased the E2F1 expression. E2F1 mRNA contains three AREs within the 3'UTR, and TTP destabilized a luciferase mRNA that contained the E2F1 mRNA 3'UTR. Analyses of point mutants of the E2F1 mRNA 3'UTR demonstrated that ARE2 was mostly responsible for the TTP-mediated destabilization of E2F1 mRNA. RNA EMSA revealed that TTP binds directly to the E2F1 mRNA 3'UTR of ARE2. Moreover, treatment with siRNA against TTP increased the proliferation of PC3 human prostate cancer cells. Taken together, these results demonstrate that E2F1 mRNA is a physiological target of TTP and suggests that TTP controls proliferation as well as migration and invasion through the regulation of E2F1 mRNA stability.

• 한국안전학회지
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• 제18권3호
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• pp.46-53
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• 2003

For the tensile tests of the F.E.M., microvoids are created by the boundary separation process at the martensite boundary or neighborhood and at inclusions within the fracture. to grow to the ductile dimple fracture. For the case of the M.E.F., microvoids created at the discontinuities of the martensite phase which exists at the grain boundary of the primary ferrite are grown to coalescence with the cleavage cracks induced at the interior of the ferrite, which as a result show the discontinuous brittle fracture behavior. In spite of their similar tensile strengths, the fatigue limit and the notch sensitivity of the M. E.F. is superior to those of the F.E.M., The M.E.F. is much more insensitive to notch than F.E.M. from the stress concentration factor($\alpha$).

• 호남수학학술지
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• 제28권2호
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• pp.197-204
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• 2006

For the evaluation algebra $F[e^{{\pm}{\chi}}]_M$, if M={$\partial$}, the automorphism group $Aut_{non}$($F[e^{{\pm}{\chi}}]_M$) and $Der_{non}$($F[e^{{\pm}{\chi}}]_M$) of the evaluation algebra $F[e^{{\pm}{\chi}}]_M$ are found in the paper [12]. For M={${\partial}^n$}, we find $Aut_{non}$($F[e^{{\pm}{\chi}}]_M$) and $Der_{non}$($F[e^{{\pm}{\chi}}]_M$) of the evaluation algebra $F[e^{{\pm}{\chi}}]_M$ in this paper. We show that a derivation of some non-associative algebra is not inner.

• 대한수학회보
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• 제44권2호
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• pp.241-246
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• 2007

For the evaluation algebra $F[e^{{\pm}x}]_M\;if\;M=\{{\partial}\}$, then $$Der_{non}(F[e^{{\pm}x}]_M)$$ of the evaluation algebra $(F[e^{{\pm}x}]_M)$ is found in the paper [15]. For $M=\{{\partial},\;{\partial}^2\}$, we find $Der_{non}(F[e^{{\pm}x}]_M))$ of the evaluation algebra $F[e^{{\pm}x}]_M$ in this paper. We show that there is a non-associative algebra which is the direct sum of derivation invariant subspaces.

• Kyungpook Mathematical Journal
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• 제58권4호
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• pp.747-759
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• 2018

A graph G = (V (G), E(G) of order n = |V (G)| and size m = |E(G)| is said to be odd harmonious if there exists an injection $f:V(G){\rightarrow}\{0,\;1,\;2,\;{\ldots},\;2m-1\}$ such that the induced function $f^*:E(G){\rightarrow}\{1,\;3,\;5,\;{\ldots},\;2m-1\}$ defined by $f^*(uv)=f(u)+f(v)$ is bijection. While a bipartite graph G with partite sets A and B is said to be bigraceful if there exist a pair of injective functions $f_A:A{\rightarrow}\{0,\;1,\;{\ldots},\;m-1\}$ and $f_B:B{\rightarrow}\{0,\;1,\;{\ldots},\;m-1\}$ such that the induced labeling on the edges $f_{E(G)}:E(G){\rightarrow}\{0,\;1,\;{\ldots},\;m-1\}$ defined by $f_{E(G)}(uv)=f_A(u)-f_B(v)$ (with respect to the ordered partition (A, B)), is also injective. In this paper we prove that odd harmonious graphs and bigraceful graphs are equivalent. We also prove that the number of distinct odd harmonious labeled graphs on m edges is m! and the number of distinct strongly odd harmonious labeled graphs on m edges is [m/2]![m/2]!. We prove that the Cartesian product of strongly odd harmonious trees is strongly odd harmonious. We find some new disconnected odd harmonious graphs.

• Kyungpook Mathematical Journal
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• 제45권2호
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• pp.293-299
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• 2005

Let ${\cal{L}}$ be a commutative subspace lattice on a Hilbert space ${\cal{H}}$ and X and Y be operators on ${\cal{H}}$. Let $${\cal{M}}_X=\{{\sum}{\limits_{i=1}^n}E_{i}Xf_{i}:n{\in}{\mathbb{N}},f_{i}{\in}{\cal{H}}\;and\;E_{i}{\in}{\cal{L}}\}$$ and $${\cal{M}}_Y=\{{\sum}{\limits_{i=1}^n}E_{i}Yf_{i}:n{\in}{\mathbb{N}},f_{i}{\in}{\cal{H}}\;and\;E_{i}{\in}{\cal{L}}\}.$$ Then the following are equivalent. (i) There is an operator A in $Alg{\cal{L}}$ such that AX = Y, Ag = 0 for all g in ${\overline{{\cal{M}}_X}}^{\bot},A^*A=AA^*$ and every E in ${\cal{L}}$ reduces A. (ii) ${\sup}\;\{K(E, f)\;:\;n\;{\in}\;{\mathbb{N}},f_i\;{\in}\;{\cal{H}}\;and\;E_i\;{\in}\;{\cal{L}}\}\;<\;\infty,\;{\overline{{\cal{M}}_Y}}\;{\subset}\;{\overline{{\cal{M}}_X}}$and there is an operator T acting on ${\cal{H}}$ such that ${\langle}EX\;f,Tg{\rangle}={\langle}EY\;f,Xg{\rangle}$ and ${\langle}ET\;f,Tg{\rangle}={\langle}EY\;f,Yg{\rangle}$ for all f, g in ${\cal{H}}$ and E in ${\cal{L}}$, where $K(E,\;f)\;=\;{\parallel}{\sum{\array}{n\\i=1}}\;E_{i}Y\;f_{i}{\parallel}/{\parallel}{\sum{\array}{n\\i=1}}\;E_{i}Xf_{i}{\parallel}$.

• 대한수학회논문집
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• 제23권2호
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• pp.153-159
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• 2008

For $\mathbb{F}[e^{{\pm}x}]_{\{{\partial}\}}$, all the derivations of the evaluation algebra $\mathbb{F}[e^{{\pm}x}]_{\{{\partial}\}}$ is found in the paper (see [16]). For $M=\{{\partial}_1,\;{\partial}_1^2\},\;Der_{non}(\mathbb{F}[e^{{\pm}x}]_M))$ of the evaluation algebra $\mathbb{F}[e^{{\pm}x},\;e^{{\pm}y}]_M$ is found in the paper (see [2]). For $M=({\partial}_1^2,\;{\partial}_2^2)$, we find $Der_{non}(\mathbb{F}[e^{{\pm}x},\;e^{{\pm}y}]_M))$ of the evaluation algebra $\mathbb{F}[e^{{\pm}x},\;e^{{\pm}y}]_M$ in this paper.

• Journal of Plant Biology
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• 제29권1호
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• pp.53-65
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• 1986

The montane forests of Ulreung Island, Korea, were investigated by the ZM school method. By comparing the montane forests of this island with those of Korean Peninsula and of Japan, a new order, F a g e t a l i a m u l t i n e r v i s, a new alliance, F a l g i o n m u l t i n e r v i s, a new association, H e p a t i c o-F a g e t u m m u l t i n e r v i s and Rhododendron brachycarpum-Pinus parviflora community were recognized. The H e p a t i c o - F a g e t u m m u l t i n e r v i s was further subdivided into four subassociations; Subass. of Sasa kurilensis, Subass. of Rumohra standishii, Subass. of Rhododendron brachycarpum and Subass. of typicum. Each community was described in terms of floristic, structural and environmental features.

• Korean Journal of Mathematics
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• 제16권3호
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• pp.323-334
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• 2008

We define injective and projective representations of quivers with two vertices with n arrows. In the representation of quivers we denote n edges between two vertices as ${\Rightarrow}$ and n maps as $f_1{\sim}f_n$, and $E{\oplus}E{\oplus}{\cdots}{\oplus}E$ (n times) as ${\oplus}_nE$. We show that if E is an injective left R-module, then $${\oplus}_nE{\Longrightarrow[50]^{p_1{\sim}p_n}}E$$ is an injective representation of $Q={\bullet}{\Rightarrow}{\bullet}$ where $p_i(a_1,a_2,{\cdots},a_n)=a_i,\;i{\in}\{1,2,{\cdots},n\}$. Dually we show that if $M_1{\Longrightarrow[50]^{f_1{\sim}f_n}}M_2$ is an injective representation of a quiver $Q={\bullet}{\Rightarrow}{\bullet}$ then $M_1$ and $M_2$ are injective left R-modules. We also show that if P is a projective left R-module, then $$P\Longrightarrow[50]^{i_1{\sim}i_n}{\oplus}_nP$$ is a projective representation of $Q={\bullet}{\Rightarrow}{\bullet}$ where $i_k$ is the kth injection. And if $M_1\Longrightarrow[50]^{f_1{\sim}f_n}M_2$ is an projective representation of a quiver $Q={\bullet}{\Rightarrow}{\bullet}$ then $M_1$ and $M_2$ are projective left R-modules.

• 대한수학회보
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• 제32권2호
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• pp.211-214
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• 1995

Let M and N be compact Riemannian manifolds and $f : M \to N$ be a smooth map. Following J. Eells, f is exponentially harmonic if it represents a critical point of the exponential energy integral $$ E(f) = \int_{M} exp(\left\$\mid$ df \right\$\mid$^2) dM $$ where $(\left\ df $\mid$\right\$\mid$^2$ is the energy density defined as $\sum_{i=1}^{m} \left\$\mid$ df(e_i) \right\$\mid$^2$, m = dimM, for orthonormal frame $e_i$ of M. The Euler- Lagrange equation of the exponential energy functional E can be written $$ exp(\left\$\mid$ df \right\$\mid$^2)(\tau(f) + df(\nabla\left\$\mid$ df \right\$\mid$^2)) = 0 $$ where $\tau(f)$ is the tension field along f. Hence, if the energy density is constant, every harmonic map is exponentially harmonic and vice versa.