• 농약과학회지
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• 제5권4호
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• pp.20-26
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• 2001

기질 물질로서 일련의3-phenyl-2,5-dihyoisoxazol-5-one(A) 및3-phenylisoxazole(B)유도체는 친핵성 첨가-제거반응($Ad_{N-E}$)으로 (A)가 (B)보다 높은 수율로 합성되었으며 정량적인 구조와 저항성(PRC) 및 감수성(SPC) 고추역병균(Phytophthora capsici)에 대한 살균 활성과의 관계(QSAR)를 검토하였다. 두 균주에 대한 살균활성은 공통적으로 benzoyl고리에 결합된 치환기의 폭인 $B_2$ 상수의 적정값(약$4.0{\AA}$)에 의존적(RPC: $(B_2)_{opt.}=3.74{\AA}$ 및 SPC: $(B_2)_{opt.}=3.99{\AA}$)이었으며 치환기가 RPC에는 전자끌게로 작용한 반면에 SPC에는 전자 끌게로 작용하지 않았다. Free-Wilson 분석결과, RPC 및 SPC, 두 균주에 대한 살균활성은 (A)가 (B)보다 컸으며 할로겐과 acetyl-치환체가 기여하였고, RPC에는 cyano, methoxy 및 methyl-치환체 등이 선택적으로 기여하였다.

• 인간식물환경학회지
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• 제24권1호
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• pp.1-16
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• 2021

Background and objective: People-nature experiences, which suggest that humans seek connections between nature and other forms of life, were presented by biologist E. O. Wilson in 1984. Biophilic design attributes support environments that can improve human connections to nature. A significant amount of literature on environmental psychology provides empirical evidence that nature benefits humans, and that practical landscape and built environments can be designed to link humans and nature (e.g., the 14 biophilic design patterns). To date, however, there has been no well-done research on reviewing the health benefits of biophilic design. Methods: The paper provides a narrative review on biophilic design and human health. The scope of this article is limited to biophilic-design books and peer-review articles related to "biophilic design," "evidence-based," "benefits," "health," rather than an attempt to identify universal issues with biophilia hypothesis. Results: A total of 45 papers were included in our review, which was related to the top five biophilic design patterns and design: the presence of natural images, the presence of plants, visual and non-visual connections to nature, and material connection with nature. These studies were related to physiology and psychology through direct or indirect connections with nature and experiences in space and place. Conclusion: This study presents two important comparisons of the empirical research on biophilic design and human health that can explain the relationship of people-nature experiences to biophilic design and human health and provides insights into related researches and recommendations for future application of our findings.

• Molecules and Cells
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• 제25권1호
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• pp.30-42
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• 2008

The disease-specific (dsp) region and the hypersensitive response and pathogenicity (hrp) genes, including the hrpW, $hrpN_{Ep}$, and hrpC operons have previously been sequenced in Erwinia pyrifoliae WT3 [Shrestha et al. (2005a)]. In this study, the remaining hrp genes, including the hrpC, hrpA, hrpS, hrpXY, hrpL and hrpJ operons, were determined. The hrp genes cluster (ca. 38 kb) was comprised of eight transcriptional units and contained nine hrc (hrp conserved) genes. The genetic organization of the hrp/hrc genes and their orientation for the transcriptions were also similar to and collinear with those of E. amylovora, showing ${\geq}80%$ homologies. However, ORFU1 and ORFU2 of unknown functions, present between the hrpA and hrpS operons of E. amylovora, were absent in E. pyrifoliae. To determine the HR active domains, several proteins were prepared from truncated fragments of the N-terminal and the C-terminal regions of $HrpN_{Ep}$ protein of E. pyrifoliae. The proteins prepared from the N-terminal region elicited HR, but not from those of the C-terminal region indicating that HR active domains are located in only N-terminal region of the $HrpN_{Ep}$ protein. Two synthetic oligopeptides produced HR on tobacco confirming presence of two HR active domains in the $HrpN_{Ep}$. The HR positive N-terminal fragment ($HN{\Delta}C187$) was further narrowed down by deleting C-terminal amino acids and internal amino acids to investigate whether amino acid insertion region have role in faster and stronger HR activity in $HrpN_{Ep}$ than $HrpN_{Ea}$. The $HrpN_{Ep}$ mutant proteins $HN{\Delta}C187$ (D1AIR), $HN{\Delta}C187$ (D2AIR) and $HN{\Delta}C187$ (DM41) retained similar HR activation to that of wild-type $HrpN_{Ep}$. However, the $HrpN_{Ep}$ mutant protein $HN{\Delta}C187$ (D3AIR) lacking third amino acid insertion region (102 to 113 aa) reduced HR when compared to that of wild-type $HrpN_{Ep}$. Reduction in HR elicitation could not be observed when single amino acids at different positions were substituted at third amino acids insertion region. But, substitution of amino acids at L103R, L106K and L110R showed reduction in HR activity on tobacco suggesting their importance in activation of HR faster in the $HrpN_{Ep}$ although it requires further detailed analysis.

• 한국환경복원기술학회지
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• 제18권6호
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• pp.135-149
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• 2015

Korean fir(Abies koreana E.H.Wilson 1920), endemic tree species of Korean peninsula, is considered as vulnerable and endangered species to recent rapid environmental changes such as land use and climate change. There are limited activities and efforts to find natural habitats of Korean fir for conservation of the species and habitats. In this study, by applying SDMs (Species Distribution Models) based on climate and topographic factors of Korean fir, we developed Korean fir's predicted distribution model and explored novel natural habitats. In Mt. Shinbulsan, Youngnam region and Mt. Songnisan, we could find korean fir's two novel habitat and the former was the warmest($13^{\circ}C$ in annual mean temperature), the driest(1,200mm~1,600mm in annual rainfall) and relatively low altitude environment among Korean fir's habitats in Korea. The result of SDMs did not include mountain areas of Gangwon-do as habitats of A. nephrolepis, because there were different contributions of key habitat environment factors, summer rainfall, winter mean temperature and winter rainfall, between A. koreana and A. nephrolepis. Our results raise modification of other distribution models on Korean fir. Novel habitat of Korean fir in Mt. Shinbulsan revealed similar habitat affinity of the species, ridgy and rocky site, with other habitats in Korea. Our results also suggest potential areas for creation of Korea fir's alternative habitats through species reintroduction in landscape and ecosystem level.

• 한국우주과학회:학술대회논문집(한국우주과학회보)
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• 한국우주과학회 2011년도 한국우주과학회보 제20권1호
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• pp.21.2-21.2
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• 2011

2010년 11월 05일부터 11월 29일 중 총 12일간 진천 소재 충북대학교 천문대의 60cm 반사망원경과 ST-8 CCD 카메라를 이용하여 BD And의 BVR CCD 측광 관측을 수행하여 처음으로 BVR 광도 곡선을 완성하였다. 또한, 극심시각 결정을 위한 측광관측이 레몬산 천문대 1m 반사망원경과 충북대학교 천문대의 35cm 망원경으로 수행되었다. 우리의 관측과 SWASP 관측을 통하여 모두 31개의 극심시각을 새로이 결정하였다. 새로운 관측은 이 별의 공전주기가 이전까지 알려진 0.4629일이 아니라 그 두 배인 0.9258일이며, 기산점도 반주기 바뀌어야 함을 보여 준다. BD And의 광도요소를 Min I = HJD 2434962.8602 + 0.d9258054 E으로 새롭게 개정하였다. 이 광도요소로 작성한 우리의 BVR 광도곡선은 제1식과 제2식의 깊이가 거의 비슷하며, 식바깥 부분에 잘 발달된 파형 모양을 보인다. 이는 BD And가 짧은 주기의 RS CVn형 식쌍성임을 나타내는 것이다. 우리의 극심시각을 포함한 총 144개의 극심시각에 대한 (O-C)도를 작성한 결과, BD And의 공전주기가 규칙적으로 변화하는 것을 발견하였다. 이 변화를 보이지 않는 제3천체에 의한 광시간 효과로 가정하여, 궤도이심율이 0.78이며, 9.19년의 주기를 가진 광시간 궤도를 결정하였다.우리의 광도곡선을 2003년 Wilson-Devinney 쌍성 모형으로 분석하여 광도곡선 해를 질량비 q=1.1822, 궤도경사각 i=$86.^{\circ}16$, $T_1$=6358(K), $T_2$=6250(K), $r_1$=1.117(Rsun), $r_2$=1.321(Rsun)와 같이 산출하였다. 식바깥에서 나타나는 파형 모양의 변화는 주성의 표면에 매우 큰 흑점으로 잘 설명되며, BVR 광도곡선에서 각각 전체 광도의 각 6.4%, 8.1%, 9.9%에 해당되는 제3 광도가 검출되었다. 이는 주기연구에서 제안된 제3천체의 존재 가능성을 더 공고히 한다.

• 한국환경복원기술학회지
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• 제19권6호
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• pp.19-30
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• 2016

The projection of climate-related range shift is critical information for conservation planning of Korean fir (Abies koreana E. H. Wilson). We first modeled the distribution of Korean fir under current climate condition using five single-model species distribution models (SDMs) and the pre-evaluation weighted ensemble method and then predicted the distributions under future climate conditions projected with HadGEM2-AO under four $CO_2$ emission scenarios, the Representative Concentration Pathways (RCP) 2.6, 4.5, 6.0 and 8.5. We also investigated the predictive uncertainty stemming from five individual algorithms and four $CO_2$ emission scenarios for better interpretation of SDM projections. Five individual algorithms were Generalized linear model (GLM), Generalized additive model (GAM), Multivariate adaptive regression splines (MARS), Generalized boosted model (GBM) and Random forest (RF). The results showed high variations of model performances among individual SDMs and the wide range of diverging predictions of future distributions of Korean fir in response to RCPs. The ensemble model presented the highest predictive accuracy (TSS = 0.97, AUC = 0.99) and predicted that the climate habitat suitability of Korean fir would increase under climate changes. Accordingly, the fir distribution could expand under future climate conditions. Increasing precipitation may account for increases in the distribution of Korean fir. Increasing precipitation compensates the negative effects of increasing temperature. However, the future distribution of Korean fir is also affected by other ecological processes, such as interactions with co-existing species, adaptation and dispersal limitation, and other environmental factors, such as extreme weather events and land-use changes. Therefore, we need further ecological research and to develop mechanistic and process-based distribution models for improving the predictive accuracy.

• Journal of Astronomy and Space Sciences
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• 제32권2호
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• pp.127-136
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• 2015

We present a by-product of our long term photometric monitoring of cataclysmic variables. 2MASS J18024395 +4003309 = VSX J180243.9 +400331 was discovered in the field of the intermediate polar V1323 Her observed using the Korean 1-m telescope located at Mt. Lemmon, USA. An analysis of the two-color VR CCD observations of this variable covers all the phase intervals for the first time. The light curves show this object can be classified as an Algol-type variable with tidally distorted components, and an asymmetry of the maxima (the O'Connell effect). The periodogram analysis confirms the cycle numbering of Andronov et al. (2012) and for the initial approximation, the ephemeris is used as follows: Min I. BJD = 2456074.4904+0.3348837E. For phenomenological modeling, we used the trigonometric polynomial approximation of statistically optimal degree, and a recent method "NAV" ("New Algol Variable") using local specific shapes for the eclipse. Methodological aspects and estimates of the physical parameters based on analysis of phenomenological parameters are presented. As results of our phenomenological model, we obtained for the inclination $i=90^{\circ}$, $M_1=0.745M_{\odot}$, $M_2=0.854M_{\odot}$, $M=M_1+M_2=1.599M_{\odot}$, the orbital separation $a=1.65{\cdot}10^9m=2.37R_{\odot}$ and relative radii $r_1=R_1/a=0.314$ and $r_2=R_2/a=0.360$. These estimates may be used as preliminary starting values for further modeling using extended physical models based on the Wilson & Devinney (1971) code and it's extensions

• 식물분류학회지
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• 제36권3호
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• pp.227-255
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• 2006

일본인 식물학자 T. Nakai는 1909년 이후 1940년까지 직접 한반도의 식물채집을 실시하였고 그의 저서 Flora Koreana 이후 한반도 식물 연구의 독보적인 학자였다. 특히, Nakai의 한반도 채집표본은 한반도 식물연구의 중요한 자료로서 활용되고 있다. 그러나, 연구문헌에 언급된 한반도내 채집지명이 Nakai의 표기방식으로 인하여 정확한 소재지가 불명확하거나 확인되지 않고 있어, 대부분 국내 학자들과 일본 학자들도 Nakai의 표기지명으로는 정확한 지명을 알 수가 없다. Nakai의 채집에 대한 정보가 매우 중요함에도 불구하고 지금까지 채집경로를 정리한 문헌이 없어 본 연구는 Nakai의 한반도 채집경로 및 일정을 정리하였다. 특히, 채집일과 장소를 날짜순으로 정리하였으며 Nakai가 표본레이블에 제시한 한자 지명을 동시에 제시하였다.

• Parasites, Hosts and Diseases
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• 제55권3호
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• pp.239-246
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• 2017

Strains of Toxoplasma gondii in Brazil are highly genetically diverse compared to strains from North America and Europe. Dogs are epidemiologically important because they act as sentinels for T. gondii infections in humans and are good indicators of environmental contamination. The aim of this study was to isolate and genetically characterize T. gondii strains from tissues of naturally infected Brazilian dogs. For this study, 21 blood samples were collected from dogs at the Zoonosis Control Centers of $Ilh{\acute{e}}us$ and Itabuna cities, Bahia, Brazil. The sera were examined for T. gondii antibodies using the indirect hemagglutination test. Brains and hearts of seropositive dogs were bioassayed in mice to isolate and characterize T. gondii parasites by PCR-RFLP using 10 genetic markers (SAG1, newSAG2, SAG3, BTUB, c22-8, c29-2, GRA6, PK1, APICO, and L358). However, T. gondii was isolated from only 4 (57.1%) dogs, designated TgDgBr6, 13, 17, and 21. All strains were virulent, causing clinical changes (rough hair coat, lethargy, and abdominal distention) and the death of all mice within 8-20 days after inoculation. Genetic analysis of these 4 T. gondii isolates revealed 4 distinct genotypes with different clonal lineage combinations (types I, II, and III) and 2 atypical alleles. Using PCR-RFLP with several markers, this study contributes to evaluations of the genetic diversity of strains circulating in Brazil.

• Journal of Ginseng Research
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• 제40권2호
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• pp.141-150
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• 2016

Background: Adipocyte-macrophage communication plays a critical role regulating white adipose tissue (WAT) inflammatory gene expression. Because WAT inflammation contributes to the development of metabolic diseases, there is significant interest in understanding how exogenous compounds regulate the adipocyte-macrophage crosstalk. An aqueous (AQ) extract of North American (NA) ginseng (Panax quinquefolius) was previously shown to have strong inflammo-regulatory properties in adipocytes. This study examined whether different ginseng extracts influence adipocyte-macrophage crosstalk, as well as WAT inflammatory gene expression. Methods: The effects of AQ and ethanol (EtOH) ginseng extracts ($5{\mu}g/mL$) on adipocyte and macrophage inflammatory gene expression were studied in 3T3-L1 and RAW264.7 cells, respectively, using real-time reverse transcription polymerase chain reaction. Adipose tissue organ culture was also used to examine the effects of ginseng extracts on epididymal WAT (EWAT) and inguinal subcutaneous WAT (SWAT) inflammatory gene expression. Results: The AQ extract caused significant increases in the expression of common inflammatory genes (e.g., Mcp1, Ccl5, Tnf-${\alpha}$, Nos2) in both cell types. Culturing adipocytes in media from macrophages treated with the AQ extract, and vice versa, also induced inflammatory gene expression. Adipocyte Ppar-${\gamma}$ expression was reduced with the AQ extract. The AQ extract strongly induced inflammatory gene expression in EWAT, but not in SWAT. The EtOH extract had no effect on inflammatory gene expression in either both cell types or WAT. Conclusion: These findings provide important new insights into the inflammo-regulatory role of NA ginseng in WAT.