• Journal of the Korean Applied Science and Technology
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• 제40권3호
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• pp.385-391
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• 2023

This study aims to examine the relationship between Serum Vitamin E and metabolic syndrome, which is a health risk, and to analyze the effect of Serum Vitamin E on the body. The analysis data were downloaded and used for the 7th 3rd (2018) data of the National Health and Nutrition Survey, and in this study, 944 men and 1,080 women were finally analyzed. For the analysis of the data, The chi-square test and t-test were used for the different values according to collected general characteristics and serum vitamin E, and the risk of metabolic syndrome was analyzed by regression, and Pearson correlation was used to confirm the correlation with each variable. Regression for Metabolic syndrome among the sub items and Serum Vitamin E showed that HDL-cholesterol was higher in the normal group than in the excess group (OR:1.042, CI:1.028-1.056), and triglycerides were significantly higher than in the normal group (OR:1.010, CI:1.009-1.012) (p<0.01). Therefore, it is proposed to develop nutrition and health programs suitable for the age of patients through this study.

• Development and Reproduction
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• 제1권1호
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• pp.25-28
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• 1997

The present study was conducted to determine the effect of recombinant human follicle stimulating hormone (rhFSH) on the estrogen synthesis by human fetal ovarian tissues. Fetal ovaries were 18-19 weeks old (18 wks:n=1, 19 wks:n=2). One case of 19-week-old fetal ovaries were obtained from anencephalic fetus. Obtained ovarieswere cleaned and diced around $600\mu\textrm{m}$ pieces, and cultured in the sandwich agar bed system for 21-23 days. Estrone ($E_{1}$) and estradiol-17 $\beta$($E_{2}$) in the medium was measured by radioimmunoassay. Amount of $E_{2}$ synthesis was greater than $E_{1}$ in both normal cases. In contrast, fetal ovaries from anencephalic fetus did not produce neither $E_{1}$ nor $E_{2}$ in the presence or absence of rhFSH. Results suggest that the fetal ovaries have a capacity of estrogen production at 18-19 weeks of gestation Existence of FSH receptor is also supposed. Different results by anecephalic fetal ovaries suggest the difference in the development between normal and anencephalic fetal ovaries.

• Speech Sciences
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• 제7권2호
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• pp.51-70
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• 2000

Twenty normal and 20 severe-to-profound hearing-impaired subjects participated in the present study. The two groups are matched by their chronological age. Each subject made a recording of three vowels of /i/, /a/, and /u/, and nine $VC_{plosive}V$ (hereafter, VCV) disyllables of /epe/, /ep'e/, /$ep^{h}e$/, /ete/, /et'e/, /$et^{h}e$/, /eke/, /ek'e/, and /$ek^{h}e$/, each five times. Formant frequencies of $F_1,\;F_2,\;and\;F_3$ were measured for the three vowels and six measures were made for the nine disyllables. The six measures were (1) the total duration of the disyllable, (2) the duration of the first vowel, (3) the duration of the closed period, (4) the ratio of the first vowel over the first vowel plus the closure period of the consonant, (5) the duration of the aspiration, and (6) the duration of the second vowel. Results shows that the three formants and each of the measures were significantly different between the two groups of subjects.

• Journal of the Korean Mathematical Society
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• 제45권5호
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• pp.1393-1404
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• 2008

Let K be a nonempty closed convex subset of a Banach space E. Suppose $\{T_{n}\}$ (n = 1,2,...) is a uniformly asymptotically regular sequence of nonexpansive mappings from K to K such that ${\cap}_{n=1}^{\infty}$ F$\(T_n){\neq}{\phi}$. For $x_0{\in}K$, define $x_{n+1}={\lambda}_{n+1}x_{n}+(1-{\lambda}_{n+1})T_{n+1}x_{n},n{\geq}0$. If ${\lambda}_n{\subset}[0,1]$ satisfies $lim_{n{\rightarrow}{\infty}}{\lambda}_n=0$, we proved that $\{x_n\}$ weakly converges to some $z{\in}F\;as\;n{\rightarrow}{\infty}$ in the framework of reflexive Banach space E which satisfies the Opial's condition or has $Fr{\acute{e}}chet$ differentiable norm or its dual $E^*$ has the Kadec-Klee property. We also obtain that $\{x_n\}$ strongly converges to some $z{\in}F$ in Banach space E if K is a compact subset of E or there exists one map $T{\in}\{T_{n};n=1,2,...\}$ satisfy some compact conditions such as T is semi compact or satisfy Condition A or $lim_{n{\rightarrow}{\infty}}d(x_{n},F(T))=0$ and so on.

• Speech Sciences
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• 제9권4호
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• pp.27-38
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• 2002

The purpose of this article is to present the acoustic parameters (VOT, jitter, shimmer, vF0, vAm, NHR, SPI, VTI, DVB, DSH) for consonants (/pipi/, /$p^{h}ip^{h}i$/, /p'ip'i/) and sustained vowels (/a/, /e/, /i/) produced by normal subjects and dysphonia patients at two vocal effort(normal, high) by Lombard effect using 60dB white noise. Lombard effect indicates the vocal effort increase in noisy situation. At normal vocal effort, in general the acoustic parameter values of patients are greater than normal. And in noisy situation, significant decrease of acoustic values is seen in normal compared with in dysphonia patients. The clinical implication of this finding, the vocal quality in dysphonia is not compensated by vocal effort as well as normal subjects because of the inefficiency caused by abnormal vocal fold appearance and function. And with this result, we can counsel that the voice quality can not be improved as well as the patient expect.

• Korean Journal of Fisheries and Aquatic Sciences
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• 제49권2호
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• pp.131-136
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• 2016

Marine organisms are sources of many bioactive compounds, such as essential fatty acids, essential amino acids, vitamins, and minerals, making them useful candidates for the production of safe bioactive substances. They also synthesize glutamic acid, which can be used to produce γ-aminobutyric acid (GABA), the major inhibitory neurotransmitter in the central nervous system (CNS), via fermentation with Lactobacillus brevis BJ-20. This study investigated the degree to which fermented sea tangle (FST) inhibits enzymes such as acetylcholine esterase (AChE) and prolyl endopeptidase (PEP) and affects memory of normal mice using the T-maze test. FST inhibited more than 90% of AChE at 1 mg/mL and 50% of PEP at 8 mg/mL. Oral FST (100 mg/kg) significantly improved performance of normal mice on the T-maze. Therefore, sea tangle fermented with L. brevis BJ20 effectively contributes to memory improvement and might be a useful functional food ingredient.

• Communications for Statistical Applications and Methods
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• 제26권5호
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• pp.431-443
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• 2019

Goodness-of-fit techniques are an important topic in statistical analysis. Censored data occur frequently in survival experiments; therefore, many studies are conducted when data are censored. In this paper we mainly consider test statistics based on the empirical distribution function (EDF) to test normal distributions with unknown location and scale parameters when data are randomly censored. The most famous EDF test statistic is the Kolmogorov-Smirnov; in addition, the quadratic statistics such as the $Cram{\acute{e}}r-von$ Mises and the Anderson-Darling statistic are well known. The $Cram{\acute{e}}r-von$ Mises statistic is generalized to randomly censored cases by Koziol and Green (Biometrika, 63, 465-474, 1976). In this paper, we generalize the Anderson-Darling statistic to randomly censored data using the Kaplan-Meier estimator as it was done by Koziol and Green. A simulation study is conducted under a particular censorship model proposed by Koziol and Green. Through a simulation study, the generalized Anderson-Darling statistic shows the best power against almost all alternatives considered among the three EDF statistics we take into account.

• Communications of the Korean Mathematical Society
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• 제27권4호
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• pp.689-699
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• 2012

(S, *) is a semigroup S equipped with a unary operation "*". This work is devoted to a class of unary semigroups, namely E-$inversive$ *-$semigroups$. A unary semigroup (S, *) is called an E-inversive *-semigroup if the following identities hold: $$x^*xx^*=x^*$$, $$(x^*)^*=xx^*x$$, $$(xy)^*=y^*x^*$$. In this paper, E-inversive *-semigroups are characterized by several methods. Furthermore, congruences on these semigroups are also studied.

• Journal of Life Science
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• 제24권3호
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• pp.260-265
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• 2014

Dried Citrus unshiu peels (Aurantii Nobilis Pericarpium; ANP) are used as a traditional folk medicine for the treatment of gastrointestinal (GI) motility disorders in East Asia, including Korea. In the present study, an ethanolic extract of ANP (ANP-E) exhibited no significant toxicity in mice, even at an oral dose of 5 g/kg. The effects of ANP-E on GI motor function were investigated by measuring the intestinal transit rate (ITR) of Evans blue in normal mice and mice with experimental GI motility dysfunction (i.e., peritoneal irritation by acetic acid; PIA). In normal mice, ANP-E significantly increased the ITR in a dose-dependent manner. The ITR in the PIA mice was significantly retarded compared to that in the normal mice. However, ANP-E significantly inhibited this retardation in a dose-dependent manner. Furthermore, in all the models, the potency of ANP-E appeared to be same or higher than that of cisapride, which was used predominantly for the treatment of various GI motility disorders in humans in the 1900s but was removed from the market in 2000 due to fatal side effects. The results suggest that ANP-E has potential as a new prokinetic agent that could be used as a substitute for cisapride.

• Biomedical Science Letters
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• 제16권1호
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• pp.1-9
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• 2010

In order to understand the effects of all-trans-RA on palate development, RA was injected into the abdominal cavity of pregnant mice and then the embryos were taken in the following days and analyzed morphologically as well as molecular biologically. When RA was administered at the stage of E11 or E15, the overall craniofacial development was retarded. The length from jaw to eye was shortened, compared to that of normal group. When the E11 embryos were exposed to RA, cleft lip was also found along with the cleft palate. In vitro palate culture experiment also revealed that RA caused cleft palate. When RT-PCR was performed, early stage administration of RA at E11 inhibited the upregulation of Hoxa7 expression at E15 through E17. Whereas in control group, high level of Hoxa7 expression was detected in the palate of E15 to E17. In the case of Bax, the expression was decreased from E16, while remaining constant in control group. When TUNEL analysis was performed following the RA treatment at E15, TUNEL positive cells were detected in the mesenchymal cells as well as epithelial cells of palatal shelves of E16 and in E17 embryos. Whereas in normal control, TUNEL positive cells were observed mostly at the epithelium around the nasal cavity and oral cavity where rugae is made. These results altogether indicate that exposure to RA during palate development causes facial deformity including cleft palate and cleft lip by modulating the expression of homeotic genes such as Hoxa7 as well as an apoptosis-related gene, Bax, and thus malregulating the apoptosis.