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The Usefulness of Comprehensive Diagnosis of Yin-deficiency and Heart Rate Variability in Halitosis Patients (구취 환자에 대한 음허 변증과 심박변이도 검사의 유용성)

  • Son, Ji-Hee;Kim, Jin-Sung;Kang, Kyung;Kim, Ju-Yeon;Seon, Jong-Ki;Han, Ga-Jin;Oh, Seung-Whan;Ryu, Bong-Ha
    • The Journal of Korean Medicine
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    • v.32 no.4
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    • pp.100-110
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    • 2011
  • Objectives: The aim of this study was to investigate the usefulness of a comprehensive diagnosis of yin-deficiency and heart rate variability in halitosis patients. Methods: We surveyed 62 halitosis patients visiting the Halitosis Clinic in the Kyung Hee University Oriental Medicine Hospital from August 2010 to April 2011. The subjects were evaluated on self-assessed severity of halitosis and xerostomia using visual analogue scale (VAS) score and yin-deficiency condition (based on the 10-item Yin-deficiency Questionnaire). Salivary function was measured by the unstimulated salivary flow rate (USFR) and heart rate variability (HRV) parameters were recorded by SA-2000E (Medicore Co. Ltd., Korea). Results: There were substantial significant positive correlations between halitosis, xerostomia VAS scores and yin-deficiency scores. There was significant negative correlation between xerostomia VAS score and USFR. Compared to the normal USFR group (USFR>0.1$m{\ell}$/min), the decreased USFR group (USFR${\leq}0.1m{\ell}$/min) showed significant lower values of Total Power (TP), Lower Frequency (LF), and High frequency (HF). Conclusions: The results of this study suggest that the comprehensive diagnosis of yin-deficiency and HRV are useful in diagnosing of halitosis patients with xerostomia. Therefore, we assume that improvement of yin-deficiency condition can be a potentially effective way to treat halitosis with xerostomia.

Comparative Analysis of the Sediment Transport Region based on the Lagrangian Concept (Lagrangian 개념에 의한 부유토사 확산범위 비교분석)

  • Cho, Hong-Yeon;Kim, Chang-Il;Lee, Khil-Ha
    • Journal of Korean Society of Coastal and Ocean Engineers
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    • v.19 no.2
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    • pp.105-112
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    • 2007
  • Sediment transport model based on the Lagrangian concept considering the grain size distribution(GSD) was setup and the change of the sediment diffusion range was analysed in the condition of considering and not considering the GSD. The GSD curve is assumed as the Log-normal distribution function in order to consider the GSD with respect to the Lagrangian concept and the random numbers, i.e. sediment particles, are generated based on the distribution function. The sediment particles is assumed as the spherical type and the random numbers based on the sediment weight is converted to the sediment diameters. Sediment transport patterns are analysed by the settling simulation, in which the settling velocity is computed by the van Rijn formulae and the horizontal diffusion coefficient is used as the constant parameter. The diffusion patterns are very similar to the patterns with GSD condition. The diffusion range defined as the range including 90%, 99% sediment weight of the total sediment weight, however, is larger than without considering GSD condition in 90%-option and shorter than with considering GSD condition in 99-option, respectively. The diffusion range is defined as tile p-percentage of the cumulative sediment weight region with reference to the 50% region, 90%- option, 99%-option, respectively.

Variation Pattern Analysis on the Air and Surface Water Temperatures of the Yellow Sea Monitoring Buoy (황해중부부이에서 관측된 기온 및 표층수온의 변화양상 분석)

  • Cho, Hong-Yeon;Jeong, Jin-Yong;Shim, Jae-Seol;Kim, Seon-Jeong
    • Journal of Korean Society of Coastal and Ocean Engineers
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    • v.22 no.5
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    • pp.316-325
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    • 2010
  • Harmonic analyses are carried out in order to obtain the major frequency components of the air temperature (AT) and surface water temperature (SWT) data monitored in the Middle Area of the Yellow Sea (Yellow Sea monitoring buoy). The analysis shows the annual and semi-annual components are predominant and the higher frequency components are relatively weak with contribution to the short fluctuations, i.e. below $0.2{\sim}0.5^{\circ}C$, in the AT and SWT. The standard deviation of the AT residual is 2.4 times larger than that of the SWT residual and the occurrence frequency distributions of the AT and SWT residual components are both closely fitted to a normal-distribution function. The variation pattern on the AT-SWT plane forms the clear continuous hysteresis loop in anti-clockwise direction which is composed of the AT-SWT rising period, AT-SWT falling period, and the constant SWT period in winter season.

System Design and Performance Analysis of a Variable Frequency LED Light System for Plant Factory

  • Han, Jae Woong;Kang, Tae Hwan;Lee, Seong Ki;Han, Chung Su;Kim, Woong
    • Journal of Biosystems Engineering
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    • v.39 no.2
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    • pp.87-95
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    • 2014
  • Purpose: The purpose of this study was to design a variable frequency LED light system for plant factory which combined red, blue, green, white, and UV lights and controlled the ratio of the light wavelength. In addition, this study evaluated the performance of each combination of LED to verify the applicability. Methods: Four combinations of LED (i.e. Red+Blue, Red+Blue+Green, Red+Blue+White, Red+Blue+UV) were designed using five types of LED. The system was designed to control the duty ratio of each wavelength of LED by 1% interval from 0~100%, the pulse by 1Hz interval from 1~20kHz. Response characteristics of the control system, spectral distribution of each combination, light uniformity and uniformity ratio were measured to test the performance of the system. Results: Clean waveforms were measured from 10Hz to 10kHz regardless of duty ratio. Frequency distortion was observed within 5% of inflection point at frequencies above 10kHz regardless of duty ratio, but it was judged negligible. Spectra showed a normal distribution, and maximum PPF with duty ratio of 100% was $271.4{\mu}mol{\cdot}m^{-2}{\cdot}s^{-1}$ for the Red+Blue combination. PPF of the Red+Blue+Green combination was $258.9{\mu}mol{\cdot}m^{-2}{\cdot}s^{-1}$, and that of the Red+Blue+White combination was $273.9{\mu}mol{\cdot}m^{-2}{\cdot}s^{-1}$. PPF of the Red+Blue+UV combination was $267.7{\mu}mol{\cdot}m^{-2}{\cdot}s^{-1}$. Uniformity ratio for the area excepting border showed 0.90 for the Red+Blue and Red+Blue+White combinations, 0.87 for the Red+Blue+Green combination, and 0.88 for the Red+Blue+UV combination. The light was irradiated evenly at the area excepting border, so it was suitable for plant growing. Conclusions: From the results of this study, response characteristics of the control system, spectral distribution of each combination, light uniformity and uniformity ratio were suitable for applying into the plant factory.

Characterization of Pseudomonas putida 1K1 Capable of Growing on Extremely High Concentration of Toluene (고농도 Toluene에서 생육 가능한 Pseudomonas putida 1K1의 특성)

  • Cho, Kyung-Yun;Chun, Hyo-Kon;Han, Dong-Cho;Kho, Yung-Hee
    • Microbiology and Biotechnology Letters
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    • v.17 no.3
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    • pp.236-240
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    • 1989
  • The isolated bacterial strain 1K1 able to grow on extremely high concentration of toluene was morphologically and physiologically best described as Pseudomonas putida. This strain could grow on at least eight aromatic compounds, e.g., benzene, benzoate, phenol, o-cresol, m-cresol, toluene, m-tolunte, and xylene, but did not Brow on alkanes, such as hexane, octane, decane, and cyclohexane. Strain 1K1 could grow on above 95% toluene, but it could not grow on above 1% of other aromatic compounds. In the point of survival, strain 1K1 was resistant to high concentration of alkanes, appreciably resistant to toluene and xylene, and damaged by to other aromatic compounds. Strain 1K1 which grew on high concentration of toluene had irregular cell shape in comparing with normal cell shape of the genus Pseudomonas. Strain 1K1 was shown to have at least two aromatic compound dissimilation pathway, one for benzoate and the other for toluene.

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Histopathologic Changes of Articular Cartilage and Subchondral Bone in Cylindrical Biopsy Specimen from Talar Osteochondral Lesions (거골의 골연골 병변의 원주형 생검에서 관절 연골과 연골하 골의 조직병리학적 변화)

  • Lee, Ho-Seong;Jang, Jae-Suk;Lee, Jong-Suk;Cho, Kyung-Ja;Lee, Sang-Hoon;Jung, Hong-Keun;Kim, Yong-Min
    • Journal of Korean Foot and Ankle Society
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    • v.10 no.2
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    • pp.117-124
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    • 2006
  • Purpose: This study was aimed at elucidating the pathogenesis of talar osteochondral lesion by analyzing the histopathological findings. Materials and Methods: Twenty specimens from 20 patients who underwent surgical treatment for talus osteochondral lesions were studied. Preoperative MRI images including T1, T2, and stir images were taken and cases were classified according to modification of the Anderson's classification. There were 5 cases of MRI group 1, 6 cases of group 2, 7 cases of group 3 and 2 cases of group 4. A full thickness osteochondral plug including the osteochondral lesion of the talus was harvested from each patient and reviewed histopathologic changes of osteochondral fragment using H-E staining. Mean diameter of specimens was 8.5 mm and mean depth was 10.3 mm. Pathologic changes of articular cartilage and subchondral bone were observed. Subchondral bone was divided into superficial, middle and deep zones according to depth. Cartilage formation, trabecular thickening and marrow fibrosis were observed in each zone. Results: There were detachment of the joint cartilage at the tidemark in 16 cases of 20 cases and the separated cartilages were almost necrotic on the histopathologic findings. Cartilage formation within subchondral bone was discovered beneath the tidemark in 12 cases. Trabeculae were increased and thickened in 17 cases. These pathologic changes were similar to fracture healing process and these findings were more conspicuous near the tidemark and showed transition to normal bone marrow tissue with depth. No correlation between the pathological progression and MRI stages was found. A large cyst shown on MRI's was microscopically turned out to be multiple micro-cysts accompanied by fibrovascular structure and newly formed cartilage tissue. Conclusion: The histopathologic findings of osteochondral lesions are detachment of overlying cartilage at the tidemark and subsequent changes of subchondral bone. Subchondral bone changes are summarized as cartilage formation, marrow fibrosis and trabecular thickening that mean healing process following repeated micro fractures of trabecular. These osteochondral lesions should have differed from osteochondral fractures.

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Correlation Analysis between Groundwater Level and Baseflow in the Geum River Watershed, Calculated using the WHAT SYSTEM (금강 유역의 지하수위와 WHAT SYSTEM을 통하여 산정된 기저유출과의 상관관계 분석)

  • Yang, Jeong-Seok;Chi, Dong-Keun
    • The Journal of Engineering Geology
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    • v.21 no.2
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    • pp.107-116
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    • 2011
  • Groundwater level data and flowrate data were collected by considering the distance between the groundwater-level gauge station and flowrate gauge station (< 10 km) in the Geum River watershed, Baseflow was separated from the collected flowrate data using the WHAT SYSTEM, which is a Web- and GIS-based tool developed for hydrological applications, Correlation analysis was performed for the separated baseflow and groundwater-level data collected from a site close to the flowrate gauge station, Twenty regions were selected and data sets were collected from 2002 to 2008. Twelve regions yielded a correlation coefficient of > 0.5, When the data sets were analyzed for each year for all 20 regions, we obtained a correlation coefficient of 0.5-0.6 for 8 cases, 0.6-0.7 for 5 cases, and > 0.7 for 12 cases. For individual regions, the correlation coefficient varied from year to year. There was a tendency toward weak correlation in the case of drought or flood, Therefore, under normal conditions (i.e., neither flood nor severe drought), it is possible to estimate the baseflow from nearby groundwater-level data for regions with a high correlation coefficient.

Fine Structure on the Epidermis of the Scalp of the Head-Irradiated Rats (방사선 조사를 받은 흰쥐 머리피부 표피층의 미세구조)

  • Ko, Jeong-Sik;Kim, Jae-Ho;Yang, Nam-Gil;Ahn, E-Tay;Park, Kyung-Ho;Kim, Jin-Gook
    • Applied Microscopy
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    • v.24 no.2
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    • pp.63-77
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    • 1994
  • This experiment was performed to study the morphological responses of the epidermis of the rat scalp, following X-ray irradiation. Male rats were divided into normal and experimental groups. Rats anesthetized with sodium thiopental, were exposed only on their head areas with a single dose of 3,000rads or 6,000rads, respectively. Radiation was produced by Mitsubishi Linea Accelerator ML-4MV at the speed of 200rads/min. The target distance was 80cm. Animals were sacrificed on six hours, two days and six days following irradiation. By the perfusion fixation through the heart, rats were fixed with 1% glutaraldehyde-1% paraformaldehyde solution. Pieces of the tissue taken from the scalp were refixed in 2.5% glutaraldehyde-1.5% paraformaldehyde solution, followed by post-fixation with 1% osmium tetroxide, and embedded within araldite mixture. The sections were cut on a LKB-V ultratome, stained with uranyl acetate and lead citrate, and were observed with JEM 100CX-II electron microscope. The results were as follow; 1. Six hours after exposure to 3,000rads of X-ray. Disrupted intercellular spaces, within which some amorphous materials were filled, disrupted mitochondria, and vacuoles in the keratinocytes were frequently observed, but six days after exposure to 3,000rads of X-ray, Morphology of the keratinocytes was generally restored. 2. Many of the morphological changes were seen on the six days after exposure to 6,000rads of X-ray. 3. Widened intercellular spaces and thickened dense plaques of the desmosomes were frequently observed after exposure to 6,000rads of X-ray. 4. In the experimental groups, the Langerhans and the Merkel cells were damaged, similarly to the keratinocyte. Above results suggest that head irradiation with the dose of 3,000rads temporarily damaged the epidermis of the scalp, though most of the structures recover within six days, whereas with the dose of 6,000rads it severely damaged the epidermis without showing any recovering tendency.

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Study on Radioprotection of Alliin and Damage Mechanism in Hepatocyte After Irradiation (방사선 피폭 시 간세포의 손상 기전과 알리인의 방어효과)

  • Ji, Tae-Jeong;Kim, Won-Tae
    • Journal of radiological science and technology
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    • v.39 no.4
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    • pp.623-630
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    • 2016
  • Liver tissue damage by a radiation exposure caused a jaundice and ascitic fluid e form harden atrophy. The reason for this lies in morphological damage of a liver cells. This study tried that observe damage mechanism of the cell organelles. It was especially observed mitochondria, endoplasmic reticulum and nuclear membrane associated with energy metabolizable. also, This study had with a radio-protector development research at the same time. Radio-protector was used to alliin that has an blood flow increase. Cell observation make used of transmission electron microscope(TEM). The result of an experiment, 7Gy of whole body irradiation was caused an inflammation in cell organelles and hypertrophy of the nucleus membrane. After 20 days, The hepatocyte has been observed in a damaged membrane on peroxisome, mitochondria and vacuole of the cell organelles. After 30 days, The hepatocyte has been observed in disconnected ribosomes on a rough endoplasmic reticulum. There was looked a giant lipoblast. There was clearly normal observed a mitochondria and nucleus membrane in the hepatocyte after alliin injection. aslo, It was no damaged the nucleus membrane. therefore, It was identified portion a radio-protector effect from alliin.

EFFECT OF SOIL mOISTURE CONDITiON ON THE GROWTH AND EVAPOTRANSPIRATION OF THE TOBACCO PLANT (토양수분의 과, 부족이 연초의 생장과 증발산량에 미치는 영향)

  • 홍순달;이윤환;김재정;조성진
    • Journal of the Korean Society of Tobacco Science
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    • v.7 no.1
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    • pp.15-23
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    • 1985
  • Growth response and evapotranspiration of tobacco as to each soil moisture condition treated with different height of ground water table such as 30cm, 100cm, 170cm, and 230cm were investigated. The results obtained were as follows; 1. Soil water potential in the rhizosphere (25cm depth from surface) treated with ground water table (G.W.T) of 230 cm was less than -6.5 bar at 60 days after transplanting. 2. Dry weight of leaves per plant was the highest in the pot treated with 100 cm G.W.T and was the lowest in the pot treated with 230 cm G.W.T.. Leaves/Stem ratio of dry weight was the lowest in the pot treated with 230 cm G.W.T. This would show that extension of leaves as compared with elongation of stem was suppressed. .3. In the roster stress condition of 230 cm G.W.T., extension of leaves was continued until the latter growth stage, Relative growth rate of leaf area per plant of the pot with 30 cm G.W.T. was the highest through all growth period after fixation of G.W.7., but owing to lower density of leaf, the dry weight of leaves per plant was less rather than that of the pot with 170 cm G.W.T. at 64 days after transplanting. 4. The highest evapotranspiration per plant per day was shown at the 45th day after transplanting in the pots with 30cm and 100cm G.W.T. and at 60 days in the pots with 170cm and 230cm G.W.T respectively. 5. In the soil moisture conditions with 30cm and 100cm G.W.T., evapotranspiration per plant per hour was much higher in the daytime that at night as well as in clear day than in rain-cloudy day owing to loner relative humidity , but in the water stress condition with 230 cm G.W.T., that was much lower. 6. Total evapotranspiration per plant during the whole growing period of 64 days was in order of 30cm > 100 cm > 170 cm > 230 cm G.W.T.. Total evapotranspiration for 34 days after fixation of G.W.T was much higher at night than in the daytime in case of water stress conditions i.e 170cm and 230cm G.W.T. but in normal condition of the pots with 30cm and 100cm G.W.T. that was much higher in the daytime than at night. 7. Leaf water potential of the 3rd and 6th leaf from top at 64 days after transplanting was in order of 100cm > 30 cm > 170cm > 230cm G.W.T. The reason why leaf water potential in the pot with 30cm was less than that in the pot with 100cm G.W.T. would be the abnormal turgidity with low density of cell substrates by the excess water absorption in the pot with 30cm G.W.T..

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