• Journal of Acupuncture Research
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• v.23 no.6
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• pp.207-219
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• 2006

Objectives : This study was to investigate the effect of low frequency electro-acupuncture (EA) at ST36 acupoint on the Freund's Complete Adjuvant(FCA)-induced arthritis in rats. Methods : Arthritis was induced by intradermal injection of FCA into base of tail. Experimental groups were divided into 4 groups; Normal, Control, ST36 and Non-Acupoint(NA). ST36 group was treated by 2 Hz EA at ST36 acupoint. Body weight, paw edema volun1e and ankle joint thickness were measured after treatment. And we investigated the effects of 2 Hz EA via WBC count, segment neurophil, lymphocyte, PGE2 assay and NADPH-d histochemistry. Results and Conclusion : The mean of body weight and ankle joint thickness of ST36 group was increased compared with control group. The mean of paw edema volume, WBC count, segment neutrophil and lymphocyte of were not decreased with control group. The mean of PGE2 concentration and NADPH-d positive neurons were changed significantly compared with control group.

• International Journal of Internet, Broadcasting and Communication
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• v.8 no.2
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• pp.49-54
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• 2016

Data delivery is very challenging in VANETs because of its unique characteristics, such as fast topology change, frequent disruptions, and rare contact opportunities. This paper tries to explore the scope of 3G-assisted data delivery in a VANET within a budget constraint of 3G traffic. It is started from the simple S_Random (Srand) and finally reached the 3GSDD, i.e., the proposed algorithm. The performance evaluation of different algorithms is done through the two metrics delivery ratio and average delay. A third function utility is created to reflect the above two metrics and is used to find out the best algorithm. A packet can either be delivered via multihop transmissions in the VANET or via 3G. The main challenge is to decide which set of packets should be selected for 3G transmissions and when to deliver them via 3G. The aim is to select and send those packets through 3G that are most sensitive and requiring immediate attention. Through appropriate communication mechanism, these sensitive information are delivered via VANET for 3G transmissions. This way the sensitive information which could not be transmitted through normal VANET will certainly find its destination through 3G transmission unconditionally and with top priority. The delivery ratio of the packets can also be maximized by this system.

• Journal of the Korean Crystal Growth and Crystal Technology
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• v.22 no.1
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• pp.29-35
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• 2012

Special attention in the role of convection in vapor crystal growth has been paid since some single crystals under high gravity acceleration of $10g_0$ appear considerably larger than those under normal gravity acceleration ($1g_0$). With increasing the gravity acceleration from $1g_0$ up to $10g_0$, the total molar flux for ${\Delta}T$ = 30 K increases by a factor of 4, while for ${\Delta}T$ = 90, by a factor of 3. The maximum molar fluxes for three different gravity levels of $1g_0$, $4g_0$ and $10g_0$, appear approximately in the neighborhood of y = 0.5 cm, and the molar fluxes show asymmetrical patterns, which indicate the occurrence of either one single or more than one convective cell. As the gravitational level is enhanced form $1g_0$ up to $10g_0$, the intensity of convection is increased significantly through the maximum molar fluxes for ${\Delta}T$ = 30 K and 90 K. At $10g_0$, the maximum total molar flux is nearly invariant for for ${\Delta}T$ = 30 K and 90 K. The total molar flux increases with increasing the gravity acceleration, for $1g_0{\leq}g_y{\leq}10g_0$, and decreases with increasing the partial pressure of component B, a noble gas called as Kr (Krypton), $P_B$. The ${{\mid}U{\mid}}_{max}$ is directly proportional to the gravity acceleration for 20 Torr $P_B{\leq}300$ Torr. As the partial pressure of $P_B$ (Torr) decreases from 300 Torr to 20 Torr, the slopes of the ${{\mid}U{\mid}}_{max}s$ versus the gravity accelerations increase from 0.29 sec to 0.54 sec, i.e. by a factor of 2. The total molar flux of $Hg_2Cl_2$ is first order exponentially decayed with increasing the partial pressure of component B, $P_B$ (Torr) from 20 Torr up to 300 Torr.

• KSBB Journal
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• v.16 no.6
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• pp.579-591
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• 2001

The cell growth inhibitor effect of cervical cancer cells was investigated by liposome mediated transfection (pRcCMVp53/lipofectin) and by transfection using adenovirus (AdCMVp57). The papilloma virus cancer cell lines we used in this study were HPV16 positive, having inhibiter gene, wild p53 gene, CaSki, SiHa, HPV18 positive HeLa, HeLaS3 and HPV negative C33A, HT3. LacZ gene of E.coli was used as the marker gene for the transfection efficiency. The effect on the inhibition of tumor cell growth was measured by cell count and cell viability though ELISA analysis and MTT assay. The inhibition of tumor cell growth was confirmed by measuring each assay for six days, comparing with the normal control cell growth. The cell growth of cervical cancer calls by transfection was significantly reduced and showed tittle differences among the cell lines. To eliminate the potential problem of Ad(adenovirus) contamination during rAAV production, rAAV can be produced by a triple transfection of vector plasmic, packaging plasmid, and adenovirus helper plasmid. To examine the helper functions of Ad plasmids on the production of rAAV vector, we carried out cotransfection of three plasmids, AAV vector, packaging construct, and Ad helper plasmids. The optimized transfection condition for calcium phosphate method is 25ug of total DNA per 10-cm-diameter plate of 293 cell. We found that rAAV yields peaked at 48hr after Ad infection. The titer of rAAV was measured by the dot blot analysis to measure the number of particles/ml based on the quantification of viral DNA. Recent1y, Kombucha(fungi) was identified as a very potent antileukefic agent. In the present study, effect of natural toxin(plankton) and Kombucha is PSP(GTXI-3, neoSTX), on various MTT assay cervical cancer cell line. Toxin(GTX 1-3, neoSTX) also inhibited the proliferation in primary cervical cancer calls in a dose-dependent toxin concentration. These results showed that toxin was very potent in inhibiting the proliferation of cervical cancer calls in vitro. Toxins and Kombuoha exhibited a dose dependent inhibition of cellular proliferation in cancer cell line.

• Journal of the Korea Concrete Institute
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• v.17 no.3 s.87
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• pp.445-454
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• 2005

Cracks due to low tensile strength in prestressed concrete (PC) beams may decrease rigidity and structural performance, resulting in excessive deflection. In an effort to solve this problem, in this research, prestressed dual concrete (PDC) has been proposed, consisting of normal strength concrete in compression zone, and high performance steel fiber reinforced concrete(HPSFRC) with a partial depth in tensile zone. Three PDC beams with different depths of HPSFRC and two PC beams were cast for experiments. Analytical models at each stage, i.e., precracking, postcracking, and ultimate, were proposed for analysis of flexural behavior in PDC beams. The experimental results agree well to the analytical ones. Crack formation and its propagation are controlled by the HPSFRC in PDC beams. The initial cracking and service limit loads are increased along with the load carrying capacity and flexural stiffness.

• Journal of the Korea Concrete Institute
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• v.25 no.3
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• pp.331-338
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• 2013

Under the paradigm of sustainable green growth at the national level, various researches and applications for energy saving in the construction field has been attempted. As a part of energy saving efforts, lightweight concrete was investigated for thermal insulation concrete with phase change material (PCM) which has high heat storage capacity. As a part of energy saving efforts, thermal insulation concrete was investigated and evaluated with lightweight aggregate impregnated by PCM which has high heat storage capacity. As a result, it is found that concrete with lightweight aggregate impregnated by PCM is effective to prevent its quality deterioration by reducing water absorption rate of lightweight aggregate. In addition, it has shown that concretes using lightweight aggregate and impregnated lightweight aggregate improve heat insulation property 33% and 40~43% compared with using normal aggregate, respectively. It is that the lightweight aggregate concrete with impregnated lightweight aggregate has 12~14% lower thermal conductivity than unimpregnated.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.29 no.4
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• pp.226-231
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• 2003

The contour of mandibular angle is important for facial esthetics in the oriental population, because the wide and square face is thought to have had an unhappy life. A prominent mandibular angle produces a characteristics quardrangle, coase, and muscular appearance. So, uni- or bi-lateral mandibular angle reduction is usually performed. However, there is little guideline for bi-lateral angle reduction. So, this study was to investigate the pattern of Korean mandibular angle for bi-lateral mandibular angle reduction as guideline. This study was included 66 adult men and women over 19 years old who are having the normal mandibular angle. We measured the posterior border, angle, and inferior border of mandible using cephalometric view. The results of study was as followed : 1. The ratio of posterior mandible was 96.6, 97.3% in male, and 103.0, 106.0% in female. 2. The ratio of mandibular angle(R1-Go/R1-R2) was 120.2% in male, and 117.3% in female. 3. The ratio of inferior mandible(D5, 6, 7, E, F, G/D4) was 97.3, 90.9, 79.5, 65.2, 57.8, 46.9% in male, and 98.5, 91.2, 80.5, 67.6, 59.1, 50.2% in female. The results of this study should be useful to decide accurate amount of reduction.

• Preventive Nutrition and Food Science
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• v.16 no.4
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• pp.283-290
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• 2011

The recent increase of colon, breast, and prostate cancer incidence in Korea has been attributed to a diet pattern change to a more Western style, in which the foods eaten are higher in protein and fat. Whether high protein intake itself stimulates tumor cell growth and exacerbates disease status has been investigated, however, many epidemiological studies have inconsistent results between meat intake and the risk of certain cancers. These inconsistent results are partly because of the difficulty of studying the effects of just the meat intake. Other factors, such as overall meal context, could not be completely excluded in the study. To address the question of whether high protein itself is independently associated with carcinogenesis, we initiated ICR mice with 200 nmol ($50{\mu}g$) 7,12-dimethylbenz[a]anthracene (DMBA) and fed animals either a normal diet (ND, 14% casein) or a high protein diet (HPD, 50% casein) for 15 weeks with 12-O-tetradecanoylphorbol-13-acetate (TPA) promotion in two-stage skin carcinogenesis protocol. There was no significant difference between ND and HPD group in food intake and body weight throughout the experiment. However, tumor multiplicity of the HPD group was decreased by 75.5% compared to that of the ND group. In addition, HPD inhibited skin hyperplasia and epidermal cell proliferation. Western analyses with whole skin lysates showed that HPD inhibited TPA-induced Akt (S473), S6K (T389), 4E-BP1 (Thr 37/46) and Erk1/2 (Thr202/Tyr204) phosphorylation as well as COX-2 expression. Taken together, these data suggest that a high protein diet has an anticarcinogenic effect by inhibiting the TPA-induced Akt signaling pathway.

• Journal of the Korean Home Economics Association
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• v.45 no.4
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• pp.113-122
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• 2007

The purpose of this study was to investigate weight control and the relative influence of individual variables affecting children's attempts to control weight. The study subjects were 319 elementary school children. First, the average body height and weight of the children who participated in this study was somewhat larger in boys and similar in girls, as compared with the normal body shape of Korean children. More boys were classified as overweight than girls, based on BMI. Both boys and girls were dissatisfied with their body shape, and especially the girls showed higher dissatisfaction rate than the boys did. Almost half of the children were concerned about weight control and girls had higher concern than boys. Of the children, 38.8% had controlled their weight; however there was no difference between their sexes. There were significant differences between children who had and had not experienced weight control in the following variables: stress caused by obesity, body satisfaction, BMI, subjective body shape perception and concern about weight control. Therefore, discriminant function analysis was performed to determine the discrimination of these variables between the two groups. From the analysis results, the most critical factor was BMI in the boys and concern about weight control in the girls. This finding should be reflected in the design of weight control programs for children i.e., boys should be encouraged to perceive correctly their own body shape and to control weight by maintaining a well-balanced diet and moderate exercise over a long period of time, rather than by skipping meals, while girls should be inspired with sound values and attitudes regarding their body shape, rather than provided with the concrete information on how to control weight.

• Biomedical Science Letters
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• v.14 no.3
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• pp.179-186
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• 2008

Matrix metalloproteinases (MMPs), also designated matrixins, hydrolyze components of the extracellular matrix. These proteinases playa central role in many biological processes, such as embryogenesis, normal tissue remodeling, wound healing, and angiogenesis, and in diseases such as atheroma, arthritis, cancer, and tissue ulceration. In previous data, disruption of the actin cytoskeleton by cytochalasin D (CD) inhibited NO-induced apoptosis, dedifferentiation, cyclooxygenase (COX)-2 expression, and prostaglandin $E_2$ production in chondrocytes cultured on plastic or during cartilage explants culture. In this study, we investigated the effects of the actin cytoskeleton architecture on MMP-2 expression and dedifferentiation by CD in rabbit articular chondrocytes. Rabbit articular chondrocytes were prepared from cartilage slices of 2-weeks-old New Zealand white rabbits by enzymatic digestion. CD was used as a disruptor of actin cytoskeleton. In this experiments measuring CD dose response, primary chondrocytes were treated with various concentrations of CD for 24h. The actin disruption was determined by immunostaining. MMP-2 expression levels were determined by immunoblot analysis and Reverse transcriptase-Polymerase chain reaction (RT-PCR) and MMP-2 activity was determined by gelatin zymography. We found that cell morphological change and up-regulation of MMP-2 expression by CD as determined via immunostaining, gelatin zymography and immunoblotting. Moreover, CD induced MMP-2 transcription was detected by RT-PCR. Also, CD-induced type II collagen expression was inhibited by MMP-2 inhibitor I treatment. Our results indicate that CD up-regulated MMP-2 activation causes dedifferentiation of articular chondrocyte.