• Journal of Korean Home Economics Education Association
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• v.28 no.1
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• pp.1-17
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• 2016

The purpose of this review was to introduce and examine 'development' and 'relations' as the core concepts of Home Economics in 2015 revised middle school curriculum in Korea. The 2009 and 2015 proclamation of the ministry of education on home economics curriculum and 26 published middle school textbooks were reviewed. The major findings were as follows. First, the components of human 'development' and family 'relations' were strongly associated with promoting four key competencies (i.e. the self-management competency, the communication competency, the aesthetic sensibility competency, the community competency) of 2015 revision. Also, four of cross-curricular learning topics (i.e. character education, multicultural education, safety and health education, human right education) in 2015 revision could be effectively discussed with human 'development' and family 'relations'. Second, when teaching and learning of the core concept, human 'development', continuous dynamic aspects of life-span development, the connectedness of different domains of development, systematic approach of various concepts in development, specificity and empirical evidence of information and variability of developmental patterns in adolescence should be considered. Third, when teaching and learning of the core concept, family 'relations', family trait such as generational relations, gender relations, role relations and power relations should be taken into account. In addition, exclusively focusing on normal family ideology or image of middle-class family and lecture-centered instruction methods should be changed for students to achieve the competencies relevant to family relations. The future directions for applying core concepts, 'development' and 'relations' in classroom will be discussed.

• Journal of Korean Medicine Rehabilitation
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• v.23 no.4
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• pp.39-57
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• 2013

Objectives The purpose of this study is to prove the effect of Kyejakjimotangkami(KMK) on osteoarthritis. Methods We checked antioxidant activity and measured production of $IL-1{\beta}$, IL-6, TNF-${\alpha}$ in RAW 264.7 cell after treat by KMK. Then we measured hind paw weight of Wister Rat with arthritis induced by MIA after KMK oral administration, checked Prostaglandin E2, IL-$1{\beta}$, IL-6, TNF-${\alpha}$, Osteocalcin, TIMP-1, MMP-9, LTB-4 in serum, ran histopathological test and ${\mu}CT$-arthrography. Results 1. DPPH radical Scavenging was increased depend on concentration of KMK ethanol extract in RAW 264.7 cell. 2. Production of NO was significantly decreased by KMK ethanol extract on concentration of $200{\mu}g/ml$ in RAW 264.7 cell. 3. Production of IL-$1{\beta}$ was significantly decreased by KMK ethanol extract on concentration of $200{\mu}g/ml$. And Production of IL-6, TNF-${\alpha}$ were significantly decreased KMK ethanol extract of every concentration in RAW 264.7 cell. 4. Result of checking hind paw weight when administered KMK ethanol extract to Wister Rat with arthritis induced by MIA was significantly higher than control group and similar to normal group. 5. Production of Prostaglandin E2, IL-$1{\beta}$, Osteocalcin, TIMP-1, MMP-9 and LTB-4 in serum was significantly decreased by KMK ethanol extract after administerd to Wister Rat with arthritis induced by MIA. 6. In Hematoxylin & Eosin staining and Safranin-O staining, we could find inflammation of synovial cell, infiltration of macrophage and granulocyte and degeneration of cartilage and bone were decreased in comparison with control group. 7. When checked cartilage volume to examine degree of cartilage degeneration using ${\mu}CT$-arthrography, volume of cartilage was increased in comparison with control group. Conclusions Comparison of the results for this study showed that KMK ethanol extract have anti-inflammatory effectiveness and can protect cartilage and bone. So we expect that KMK can be used as a effective drugs for osteoarthritis.

• The Journal of Pediatrics of Korean Medicine
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• v.22 no.2
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• pp.81-114
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• 2008

Objectives : The purpose of this study is to investigate the effect of Jeseupwiryeongtang-gagam(JWTG) on atopic dermatitis by in vivo experiment using NC/Nga atopic dermatitis mouse, which has histological and clinical similarities to the atopic dermatitis of human. Methods : To investigate the effect of JWTG on AD, we evaluated atopic dermatitis-like skin lesions by clinical skin index and analyzed immunological parameters in peripheral blood mononuclear cells(PBMCs), splenocytes, draining lymph node(DLN) and performed skin histology in ears and dorsal skin of atopic dermatitis-like skin NC/Nga mouse in vivo. Results and Conclusions : In vivo, clinical skin severity score were significantly lower in JWTG group than control group. IgE, IL-6, $TNF-{\alpha}$, IgM, IgG2a and IgG2b levels in serum were decreased remarkably in JWTG group than control group and $IFN-{\gamma}$ production, secreted in Th1 cell were increased by JWTG. After experiment ended, we analyzed immunological cells ($CD3^+$, $CD19^+$, $CD4^+$, $CD8^+$, $CD3^+$$CD69^+$, $CD4^+$$CD25^+$ and $CD49b^+$) by flow cytometry. It resulted that total absolute number of $CD3^+$, $CD19^+$, $CD4^+$ and $CD8^+$ cells were recovered as normal and $CD3^+$$CD69^+$ were decreased significantly compared with control group in isolated DLN and PBMCs from NC/Nga mouse and total absolute number of $Gr-1^+$, $CD11b^+$ and $CD3^+$ in dorsal skin of NC/Nga mouse were decreased by JWTG. We analyzed ear, DLN, and neck-back skin after biopsy and dyeing by hematoxyline/eosin(H&E) and toluidine staining (mast cells marker) and obtained results that JWTG were effective to histological symptoms (dermal and epidermal thickening, hyperkeratosis and inflammatory cell infiltration). Ear thickness was decreased significantly than the control group and the size of inflammatory lymphocytes cells(ILC) and plasma cells(PC) in DLN were also decreased.

• Journal of Life Science
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• v.14 no.5
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• pp.847-854
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• 2004

Allergy is a multi-factorial disease influenced by genetic and environmental factors. As the number of allergy-affected people is increasing in developed countries, there is an increasing interest in genetic predisposition to the allergy. A number of genes and chromosomal region have been identified to be linked to allergy including rhinitis, asthma and atopy. In order to understand the genetic background for the allergy-affected people, we investigated genetic predisposition among students enrolled in Busan Science Academy. Among 138 students, about 30% students had some allergy-related disorder including rhinitis, asthma and atopy. We analyzed several single nucleotide polymorphisms (SNPs) within two genes, Inter-leukin-4(IL-4) and Interleukin-4 receptor(IL-4R), which are involved in the induction of allergy reaction with the Th2 immunity. For 96 samples obtained from students, we analyzed 9 SNPs including -590 C/T and -34 C/T in IL-4, and I75V, Q576R, E375A, e406R, 5411L, S761P and S727A in IL-4R. From the analysis, these SNPs showed slight differences among normal and allergy-affected students, but these differences was not enough to predict the predisposition to the allergy. In contrast to previous reports, we could not find SNP(s) related with allergy. These results suggest that genetic tests recently performed in Korea widely have to be reassessed for its validity of genetic predisposition. [Supported by grants from MOST]

• Journal of Korean Tunnelling and Underground Space Association
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• v.17 no.4
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• pp.473-485
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• 2015

The problems for non-rotating of a disc cutter proceed from the faults in inner parts of the disc cutter such as the leak of hydraulic fluid, the intrusion of tunnel mucks and water, overloading, overheating, poor assembly and substandard material. The rotating of a disc cutter is an indicator to show that the inner parts of disc cutter is operable, although the rotational torque depends on the extent of the damage. Therefore, the key in the problems for non-rotating of disc cutter is to maintain that the tapered roller bearings are working properly. This study aims to investigate the inner parts disassembled from disc cutters applied to the field tests in order to help decision for reuse of the disc cutters. As results, surface finishing to remove the scratch on the load zone of the hubs is needed, with the intent to reuse a hub. And the investigation of lapping surface by optical microscope of floating seals and the contamination test of oil need to be performed for reuse of a disc cutter. Especially, the analysis results show that the floating seals play a key role in the normal operation of bearings. There is nothing significant to report in the rest parts such as bearing, shaft, seal retainers.

• Korean journal of applied entomology
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• v.10 no.1
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• pp.31-38
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• 1971

Tolerance test in plastic vat, pot and fold tests were carried out to investigate the selective herbicides for soybean culture in sandy loam. The soybean plants showed great tolerance against herbicides such as Tri-allate (Avadex-BW), Alachlor (Lasso), Butachlor (Machete), Propachlor (Ramrod), Nitrofen (TOK), MO, HE-314, Nitrofen/Dinoseb(TOK/DNBP), and Chlo.oxu.on (Tenoran), and the growth was normal even when each was treated with the herbicides up to 2ft3 times of the recommended concentrations. Soybean plants showed a slight tolerance against Prometryne (Gesagard), Propazine (Gegamil), Diuron (Karmex), Metabromuron (Patoran), Linuron (Lorox) and Swep when each was treated with herbicides up to 1-2 times of the recommended concentrations. Great injury or withering was noticed due to the high sensitivity of soybean to Simazine (CAT) and to Floumetron (Cotoran). In pot and field experiments with herbicides such as Butachlor (Machete), Alachlor (Lasso), Nitrofen (TOK), Kerb, Nitrofen/Dinoseb (TOK/DNBP), Swep, Linuron (Lorox), Simazine (CAT) and PCP, the following results were obtained: Great injuries were noticed with Simazine (CAT). Also, Linuron (Lorox) and Kerb showed a slight injury at early growth stage of soybean, Nitrofen (TOK) , Nitrofen/Dinoseb (TOK/DNEP), Alachlo. (Lasso), Butachlo. (Machete) and Swep had high selectivities for soybean and no injury was noticed. With respect to herbicidal effects there was a greatly significant difference between treated plots and non-treated plots with the exception of Simaaine (CAT) plot in field test. E. crusgalli and C. sanguinalis were tolerant against Simazine(CAT) and Linuron(Lorox). Cyperus and E. annuus were tolerant against Kerb. Great herbicidal effects on grasses were observed in Alachlor (Lasso) and Butachlor (Machete) plots. Among broad-leaf weeds, P. hydropiper and C. album were tolerant against Butachlor (Machete) and Alachlor (Lasso). When soybean was treated with the herbicides such as Alachlor (Lasso) (ai. 150g/10a), Butachlor (Machete) (ai. 300g/10a), Nitrofen (TOK) (ai. 250g/10a), Linuron (Lorox) (ai. 75g/10a) once after seeding, no additional wording was required till harvest.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.30 no.1
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• pp.79-83
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• 2004

In order to investigate the beneficial effects of parsely (Petroselinurn sativum) extract on skin, we measured the synthesis of total collagen and type I procollagen in cultured normal human fibroblast (NHF), the synthesis of prostaglandin E$_2$(PCE$_2$), interleukin 1 ${\alpha}$(IL -1 ${\alpha}$) and tumor necrosis factor ${\alpha}$ (TNF ${\alpha}$) in HaCaT cell and we also measured dermal thickness and density in hairless mouse (Female albino hairless mice, Skh:hr-1). As the results, the synthesis of total collagen and type I procollagen were increased 23％ and 18％ respectively, after 1 $\mu\textrm{g}$/mL parsley extract treatment. The producions of PGE$_2$ induced by UVB irradiation were decreased 60％ after 1 $\mu\textrm{g}$/mL parsley extract treatment. The treatment with 1 $\mu\textrm{g}$/mL parsley extract also decreased the synthesis of IL -1 ${\alpha}$ and TNF ${\alpha}$ induced by 10 uM RA, 100 $\mu\textrm{g}$/mL SLS and 30 mJ/$\textrm{cm}^2$ UVB irradiation, After 4 days treatment with 1％ parsley extract, the dermal thickness of hairless mouse was increased 1.5 times and the density of dermis was tighter than control. These results indicate that parsley extract have anti-aging and anti-irritation effects on skin.

• Proceedings of the Korean Society of Crop Science Conference
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• 2017.06a
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• pp.196-196
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• 2017

Oilseed crop Camelina (Camelina sativa L.) is a suitable for biodiesel production that has high adaptability under low-nutrient condition like marginal land and requires low-input cost for cultivation. Enhanced abiotic stress tolerance of Camelina is very important for oil production under the wide range of different climate. CsRCI2s (Rare Cold Inducible 2) are related proteins in various abiotic stresses that predicted to localized at plasma membrane (PM) and endoplasmic reticulum (ER). These proteins are consist of eight-family that can be divided into tail (CsRCI2D/E/F/G) and no-tail (CsRCI2A/B/E/H) type of C-terminal. However, it is still less understood the function of C-terminal tail. In this study, CsRCI2D/H genes were cloned through gateway cloning system that used pCB302-3 as destination vector. And we used agrobacterium-mediated transformation system for generation of overexpression (OX) transformants. Overexpression of target gene was confirmed using RT-PCR and segregation ratio on selection media. We analyzed physiological response in media and soil under abiotic stresses using CsRCI2D and CsRCI2H overexpression plant. To compare abiotic stresses tolerance, wild type and CsRCI2D/H OX line seeds were sown on agar plate treated with various NaCl and mannitol concentration for 7 days. In the test of growth rate under abiotic stress on media, CsRCI2H OX line showed similar to NaCl and mannitol stress. In the other hand, CsRCI2D OX line showed to be improved stress tolerance that especially increased in 200mM NaCl but was similar on mannitol media. In greenhouse, WT and CsRCI2D/H OX lines for physiological analysis and productivity under abiotic stresses were treated 100, 150, 200mM NaCl. Then it was measured various parameters such as leaf width and length, plant height, total seed weight, flower number, seed number. CsRCI2H OX line in greenhouse did not show any changes in physiological parameters but CsRCI2D OX line was improved both physiological response and productivity under NaCl stress. Among physiological parameters of CsRCI2D OX line under NaCl stress, leaf length and width were observed shorter than WT but it were slightly longer than WT in 200mM NaCl stress. Furthermore, total seed weight of CsRCI2D OX line under stress displayed to decrease than WT in normal condition, but it was gradually raised with increasing NaCl stress then more than WT relatively. These results suggested CsRCI2D might be contribute to improve abiotic stress tolerance. However, function of CsRCI2H is need to more detail study. In conclusion, overexpression of CsRCI2s family can generate various environmental stress tolerance plant and may improve crop productivity for bio-energy production.

• Journal of Korean Society of Steel Construction
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• v.27 no.2
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• pp.195-205
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• 2015

The rahmen bridge is well known common type of bridge in which all members are connected rigidly. The rahmen bridge is built for several situations because it has many advantages such as no need of bridge bearing system, easy of maintenance, reduction of the cross-sectional area of superstructure, and relatively low construction cost compared with other bridge types. Recently, to lengthen the span of rahmen bridge system, steel-concrete composite beam is used for superstructure of rahmen bridge instead of normal concrete girder with slab. However, member forces are increased because of extension of span length of superstructure and substructure is designed and constructed inefficiently when steel-concrete composite rahmen bridge is designed. In this study, new-type steel-concrete composite bridge is suggested. New-type steel-concrete composite rahmen bridge is adopted hinge connection between abutment and foundation for the reduction of the bending momemt at the foundation. In this study, we present the results of experiment conducted to estimate the load carrying capacity of new-type steel-concrete composite rahmen bridge and the structural characteristics of hinge connection.

• Fire Science and Engineering
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• v.20 no.3 s.63
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• pp.35-41
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• 2006

In this study, we presented the problems in the insulation cover of 22.9kV transformer bushing through investigating actual conditions. After thermal stress applied to the insulation cover, deterioration patterns, thermogravimetric and infrared characteristics were analyzed, and the results were applied to the cause analysis of accidents and judgement of safety. The insulation covers are used to protect exposed terminals of transformer, but they had improper size and length. Therefore, they could not show efficient insulation function. In case that thermal stress of $150^{\circ}C$ was applied to the insulation covers, plastic insulation covers(A, B, D, E) damaged severely, whereas rubber insulation cover(C) showed normal shapes. In the result of thermogravimetric analysis, the thermal gravity of plastic covers(A) decreased about 33.3% at $307.8^{\circ}C\;to\;405.9^{\circ}C$. and he thermal gravity of rubber covers (C) decreased about 53.7% at $258.8^{\circ}C\;to\;32.9^{\circ}C$. In the result of FT-IR analysis, plastic covers showed peaks characteristic of $CH_2,\;CH_3$, C=O and C=C bonds, whereas rubber covers showed peaks characteristic of OH, $CH_2,\;CH_3$, C=O, C=N and C=C bonds.